The Interaction of Lisuride, an Ergot Derivative, with Serotonergic an. (erowid.org)
Hydrogen3
Lisuride is described as the free base and as the hydrogen maleate salt. (wikipedia.org)
Direct Dopaminergic Action Of Lisuride Hydrogen Maleate, An Ergot Deri. (erowid.org)
The hallucinogenic chemicals (+/-)-2,5-dimethoxy-4-iodoamphetamine (DOI) and lysergic acid diethylamide (LSD) stimulated a head-twitch behavioral response that was not observed with the nonhallucinogenic lisuride hydrogen maleate (LHM) and was absent in receptor null-mutant mice. (thevespiary.org)
Dopaminergic2
Lisuride dose-dependently suppresses prolactin levels due to its dopaminergic activity. (wikipedia.org)
Lisuride and LSD: Dopaminergic and Serotonergic Interactions in the "S. (erowid.org)
Serotonergic1
Minute amounts of lisuride suppress the firing of dorsal raphe serotonergic neurons, presumably due to agonist activity at 5-HT1A receptors. (wikipedia.org)
Symptoms1
The use of lisuride as initial antiparkinsonian medication for Parkinson's disease has been advocated, delaying the need for levodopa until lisuride becomes insufficient for controlling the parkinsonian symptoms. (wikipedia.org)
Response1
Response of central monoaminergic neurons to lisuride: comparison with. (erowid.org)
Effects8
Side effects of lisuride include nausea and vomiting, dizziness, headache, fatigue or drowsiness, insomnia or sleep, gastrointestinal disturbances such as abdominal pain or diarrhea, nasal congestion or runny nose, and hypotension, hallucinations or confusion (particularly at higher doses). (wikipedia.org)
Side effects of lisuride include nausea and lowered blood pressure, among others. (wikipedia.org)
Research suggests that the lack of psychedelic effects with lisuride arises from biased agonism of the 5-HT2A receptor. (wikipedia.org)
Lisuride and D-LSD: Effects on the monoaminergic system in the rat bra. (erowid.org)
Effects of lisuride and LSD on cerebral monamine systems and hallucino. (erowid.org)
Pharmacological Effects Of Lisuride In Rodents Mediated By Dopaminergi. (erowid.org)
Lisuride-Induced Mounting Behavior and Effects on the Monoaminergic Sy. (erowid.org)
Pharmacological Effects of Lisuride and Their Potential Role in Furthe. (erowid.org)
Acts1
Lisuride acts as a mixed agonist and antagonist of dopamine, serotonin, and adrenergic receptors. (wikipedia.org)
Hydrogen maleate2
Lisuride is described as the free base and as the hydrogen maleate salt. (wikipedia.org)
The hallucinogenic chemicals (+/-)-2,5-dimethoxy-4-iodoamphetamine (DOI) and lysergic acid diethylamide (LSD) stimulated a head-twitch behavioral response that was not observed with the nonhallucinogenic lisuride hydrogen maleate (LHM) and was absent in receptor null-mutant mice. (thevespiary.org)
Prolactin levels3
Lisuride, sold under the brand name Dopergin among others, is a monoaminergic medication of the ergoline class which is used in the treatment of Parkinson's disease, migraine, and high prolactin levels. (wikipedia.org)
Lisuride dose-dependently suppresses prolactin levels due to its dopaminergic activity. (wikipedia.org)
Effect of Lisuride on serum prolactin levels during puerperium. (nih.gov)
Pergolide1
As an antagonist of the 5-HT2B receptor, lisuride has no risk of cardiac valvulopathy in contrast to related ergolines like pergolide and cabergoline. (wikipedia.org)
Effectiveness2
The effectiveness of lisuride in Parkinson's disease and hyperprolactinemia is thought to be mostly due to activation of dopamine D2 receptors. (wikipedia.org)
Lactation inhibition with various dosages of lisuride--prolactin secretion and effectiveness]. (nih.gov)
Treatment3
additional citation(s) needed] Evidence is insufficient to support lisuride in the treatment of advanced Parkinson's disease as an alternative to levodopa or bromocriptine. (wikipedia.org)
Treatment with 600 or 900 micrograms lisuride over 14 days (each test group n = 25) caused an immediate drop of elevated prolactin (PRL) levels in all patients in comparison to values seen in normal, nonpregnant women (less than 30 ng/ml). (nih.gov)
Severe side effects were not observed during lisuride treatment with these dosages. (nih.gov)
Similar1
The postsuckling PRL increase was abolished by a single oral dose of lisuride (100, 200, 300 micrograms), similar to that seen with bromocrytine (2.5 mg). (nih.gov)
Side2
Side effects of lisuride include nausea and vomiting, dizziness, headache, fatigue or drowsiness, insomnia or sleep, gastrointestinal disturbances such as abdominal pain or diarrhea, nasal congestion or runny nose, and hypotension, hallucinations or confusion (particularly at higher doses). (wikipedia.org)
Side effects of lisuride include nausea and lowered blood pressure, among others. (wikipedia.org)
Oral1
Absorption of lisuride from the gastrointestinal tract with oral administration is complete. (wikipedia.org)