• By analysing tum/RacGAP50C mutant Drosophila embryos we show that cells lacking Tum do not form furrows and fail to localise the key cytokinetic components Pebble (a RhoGEF), Aurora B kinase, Diaphanous, Pav-KLP and Anillin. (biologists.com)
  • We have previously found empirical evidence for antagonistic coevolution between the sex chromosomes in Drosophila melanogaster (see Lund-Hansen et al 2021, https://www.pnas.org/doi/full/10.1073/pnas.2003359118 ) and are now interested in determining how expression is altered in males with mis-matched sex chromosomes. (lu.se)
  • We expect that spotted wing drosophila populations will build rapidly in the coming weeks as more food becomes available for the flies, especially if conditions remain warm and we get more rain. (umaine.edu)
  • Start protective sprays on any berries that have begun to ripen, when more than six spotted wing drosophila flies are caught in a trap, or any larvae are noticed in the fruit. (umaine.edu)
  • To understand the basic neural pathway underlying the modulation of this innate behavior, we established a behavioral assay in Drosophila melanogaster and investigated the relationship between sexual experience and aggression. (nih.gov)
  • used a series of genetic experiments and high speed-videos to assess how mutations in male yellow fruit flies affected their mating behavior. (elifesciences.org)
  • Another circadian behavior in Drosophila is courtship between the male and female during mating. (wikipedia.org)
  • In Drosophila , InsP 3 R activity is required in aminergic interneurons during pupal development for normal flight behavior. (jneurosci.org)
  • Fruitless AS isoforms have been shown to influence male courtship behavior, but the underlying mechanisms are unknown. (princeton.edu)
  • Using genome-wide approaches and quantitative behavioral assays, we show that the P-element somatic inhibitor (PSI) and its interaction with the U1 small nuclear ribonucleoprotein complex (snRNP) control male courtship behavior. (princeton.edu)
  • The PSI&AB mutant results in significant changes in the AS patterns of ∼1,200 genes in the Drosophila brain, many of which have been implicated in the regulation of male courtship behavior. (princeton.edu)
  • This study reinforces the importance of AS in the control of gene activity in neurons and integrated neuronal circuits, and provides a surprising link between a pleiotropic pre-mRNA splicing pathway and the precise control of successful male mating behavior. (princeton.edu)
  • Drosophila has proven to be a useful model system for analysis of behavior, including flight. (jove.com)
  • Drosophila has long been used to study the genetic basis of behavior 1 , and researchers have devised a number of ways to analyze various types of behavior 2-6 . (jove.com)
  • BMP-regulated exosomes from Drosophila male reproductive glands reprogram female behavior. (ox.ac.uk)
  • Here we show that male identity of the blood-brain barrier is necessary and that male-specific factors in the bbb are physiologically required for normal male courtship behavior. (utmb.edu)
  • These data identify sex-specific factors and signaling processes in the bbb as important regulators of male mating behavior. (utmb.edu)
  • Drosophila micromelanica Patterson is a member of the subgenus Drosophila, related both to D. melanica and to D. mulleri. (caltech.edu)
  • In the presence of mating partners, adult male flies exhibited elevated levels of aggression, which was largely suppressed by prior exposure to females via a sexually dimorphic neural mechanism. (nih.gov)
  • The suppression involved the ability of male flies to detect females by contact chemosensation through the pheromone-sensing ion channel ppk29 and was mediated by male-specific GABAergic neurons acting on the GABAA receptor RDL in target cells. (nih.gov)
  • he noted that yellow mutant males, named for their loss of black pigment that gives their body a more yellow appearance ( Figure 1A ), mated successfully with wild-type females much less often than wild-type males. (elifesciences.org)
  • In Drosophila, males instinctively pursue females with a lengthy and elaborate courtship ritual triggered by activation of sexually dimorphic P1 interneurons. (cdc.gov)
  • We gave uninfected females the opportunity to copulate twice in no-choice trials: either with two uninfected males, or with one male infected with sigma virus followed by an uninfected male. (uky.edu)
  • We assessed whether females respond behaviorally to male infection, determined whether male infection affects either female or male reproductive success, and measured offspring infection rates. (uky.edu)
  • Thus viral infection may provide males an advantage in sperm competition, or, possibly, females may preferentially use infected sperm. (uky.edu)
  • Males differ in the external genitalia, while trained observers can separate females using colour characteristics. (wikipedia.org)
  • D. melanogaster females crossed to D. simulans males produce sterile F1 females and no F1 males. (wikipedia.org)
  • D. simulans will mate with these sister species to form fertile females and sterile males, a fact that has made D. simulans an important model organism for research into speciation. (wikipedia.org)
  • D. simulans are monomorphic in their pheromone profiles where both males and females largely produce the cuticular hydrocarbon pheromone 7-tricosene (7-T). The ability of males within the D. melanogaster subgroup to discriminate between conspecific and heterospecific females is due in part to the differential valence of the cuticular hydrocarbon 7,11-heptacosadiene (7,11-HD), which is produced by D. melanogaster and D. sechellia females. (wikipedia.org)
  • Among Drosophila simulans inbred males, two fitness characteristics, fertility and attractiveness to females, are especially susceptible to inbreeding depression. (wikipedia.org)
  • We determined the levels of 400 different lipids in the non-gonadal soma of D. melanogaster females and males. (usuhs.edu)
  • We found higher levels of saturated cholesterol esters and lysophosphatidylcholine in males, and higher levels of polyunsaturated cholesterol esters in females. (usuhs.edu)
  • We also determined the levels of these lipids in females and males without a germline to determine if the absence of gamete "sinks" for metabolic products, such as yolk and lipid deposits in eggs, altered somatic lipid profiles. (usuhs.edu)
  • This signaling is involved in blocking the rapid remating of mated females, which contributes to the reproductive advantage of the first male to mate. (ox.ac.uk)
  • Drosophila females are larger than males. (greatgreenwedding.com)
  • The male fruit fly is smaller than the female, the amount of pigment in the tip of the male abdomen is greater than the one in the females, the male has fewer abdominal segments than females, and male have sex combs. (greatgreenwedding.com)
  • Males have dark, rounded genitalia at the tip of their abdomen, whereas females have light, pointed genitalia. (greatgreenwedding.com)
  • When they mate, the males introduce sperm into female bodies, and females develop and lay eggs to create the next generation of flies. (greatgreenwedding.com)
  • Generally, the abdomens of males tend to be stubbier and more darkly pigmented than females (Fig. 3). (greatgreenwedding.com)
  • Ejaculate chemicals transferred from males to females during mating cause significant changes in female behaviour and physiology, but the causes of phenotypic variation in these responses is little understood. (uea.ac.uk)
  • We exposed adult females to five different diets and kept them continuously with males that did or did not transfer SP. (uea.ac.uk)
  • Importantly, diet also significantly affected whether exposure to SP transferring males was beneficial or costly to females, with beneficial effects occurring more often than expected. (uea.ac.uk)
  • We found that dietary yeast deconsolidated the sleep-wake behaviour of flies by promoting arousal from sleep in males and shortening periods of locomotor activity in females. (bournemouth.ac.uk)
  • Increasing the dietary sucrose concentration from 5% to 35% had no effect on total sucrose ingestion per day nor any affect on arousal, however it did lengthen the time that males and females remained active. (bournemouth.ac.uk)
  • Beaded Minute males are not intersexual, but are often aberrant because of incomplete development of the anal and genital imaginal discs-as are also Beaded Minute females. (caltech.edu)
  • These matings included at least 500 mass cultures, of which 74 produced hybrid offspring -- a total of 532 females and 635 males, all wild type for the sex -- linked mutant characters used. (caltech.edu)
  • It was shown by Lancefield (1929) that D. pseudoobscura A-B hybrid females, when back-crossed either to A or to B males, give sex-ratios among their offspring that may deviate widely (in either direction) from 1:1. (caltech.edu)
  • Race B females of Drosophila pseudoöbscura crossed to race A males produce sterile F1 hybrid males having visibly small testes. (caltech.edu)
  • Before fertilization, the cytoplasm of the eggs deposited by race B females is so influenced by the chromosomes present in it, that an interaction between this cytoplasm and the autosomes of race A (introduced by the spermatozoon) results in the development of small testes in males arising from such eggs. (caltech.edu)
  • There was support for this hypothesis in the male response to selection, but not for selected-line females. (unl.edu)
  • Females also moved less than males, perhaps due to behaviors related to oviposition whereas elevated male activity might be due to behaviors associated with seeking females and courtship. (unl.edu)
  • In the present study, the occurrence or not of associative learning in A. obliqua females and males of different ages and nutritional states concerning sucrose (carbohydrate) and brewer´s yeast (protein source) was observed. (bvsalud.org)
  • Associative learning for sucrose was demonstrated in young and old females and males only when deprived of food for 2 days after the experience period. (bvsalud.org)
  • Franceschetti and Jadassohn distinguished Naegeli syndrome from incontinentia pigmenti (Bloch-Sulzberger syndrome) by the equal frequency of the disorder in males and females and by the presence of palmar and plantar hyperkeratosis, hypohidrosis, and dental abnormalities. (medscape.com)
  • My main interest is in the evolutionary genetics of sex differences, especially sexually antagonistic genetic variation-in other words, when the same gene has opposite effects on the fitness of males and females. (lu.se)
  • Circadian clock disruption promotes the degeneration of dopaminergic neurons in male Drosophila. (cdc.gov)
  • Sperm competition between Drosophila males involves both displacement and incapacitation. (uchicago.edu)
  • We found significant differences in recovery rate, organ sizes, sperm production and other key reproductive traits among males from our different temperature treatments. (authorea.com)
  • Epigenetic maintenance of telomere identity in Drosophila: buckle up for the sperm ride. (ens-lyon.fr)
  • Home / Teams / Epigenetics and Zygote Formation - B. Loppin / Publications / Epigenetic maintenance of telomere identity in Drosophila: buckle up for the sperm ride. (ens-lyon.fr)
  • Analysis of Bub3 and Nup75 in the Drosophila male germline lineage. (bvsalud.org)
  • Extensive communication at the stem cell -niche interface and asymmetric stem cell division is key for the homeostasis of the Drosophila male germline stem cell system. (bvsalud.org)
  • In sum, our analysis shows that Bub3 and Nup75 are required for male germline development and maintenance . (bvsalud.org)
  • In particular, HEG gene drive could be particularly effective if activity was restricted to the male germline to target genes required for female fertility/viability or engineered to destroy the X-chromosome by cutting at multiple X-specific sites [5] , [6] . (plos.org)
  • The available experimental data support the hypothesis that the cap cells(CpCs) at the anterior tip of the germarium form an environmental niche for germline stem cells (GSCs) of the Drosophila ovary. (biologists.com)
  • Drosophila circadian rhythm have paved the way for understanding circadian behaviour and diseases related to sleep-wake conditions in other animals, including humans. (wikipedia.org)
  • Drosophila circadian rhythm was discovered in 1935 by German zoologists, Hans Kalmus and Erwin Bünning. (wikipedia.org)
  • Drosophila melanogaster males perform a series of courtship behaviors that, when successful, result in copulation with a female. (elifesciences.org)
  • Greenspan, 2008 ), Margaret Bastock compared courtship of yellow mutant and wild-type males and concluded that despite all courtship actions being present, loss of yellow function likely reduces courtship vigor or drive, leading to copulation inhibition ( Bastock, 1956 ). (elifesciences.org)
  • Courtship involves a song accompanied by a ritual locomotory dance in males. (wikipedia.org)
  • Perfuming a D. simulans female with 7,11-HD is sufficient to suppress D. simulans male courtship. (wikipedia.org)
  • Feminization of the bbb of adult males significantly reduces male courtship. (utmb.edu)
  • We show that the bbb-specific G-protein coupled receptor moody and bbb-specific Go signaling in adult males are necessary for normal courtship. (utmb.edu)
  • Drosophila willistoni (Sturtevant, 1916) is a species of the willistoni group of Drosophila having wide distribution from the South of USA (Florida) and Mexico to the North of Argentina. (scielo.br)
  • Drosophila willistoni (Sturtevant, 1916) é uma espécie do grupo willistoni de Drosophila que apresenta ampla distribuição geográfica desde o sul dos Estados Unidos (Flórida) e México até o norte da Argentina. (scielo.br)
  • As a result, the yellow males would court female flies but were then unable to grab and mount them. (elifesciences.org)
  • Drosophila CHCHD2 ( dCHCHD2 ) knockout flies exhibit PD-like phenotypes in an age-dependent manner, which include dysfunction in motor ability, DA neuron loss, increased oxidative stress and mitochondrial cristae degeneration 2 . (nature.com)
  • What are the differences between male and female fruit flies quizlet? (greatgreenwedding.com)
  • Are male fruit flies smaller? (greatgreenwedding.com)
  • Why is it important to be able to differentiate between male and female flies? (greatgreenwedding.com)
  • To ensure that you have the appropriate mix of male and female flies in your cross. (greatgreenwedding.com)
  • If you are unable to correctly separate male and female flies, your cross may only contain a single sex or have the incorrect genotype. (greatgreenwedding.com)
  • Are all flies male? (greatgreenwedding.com)
  • Higher dietary sucrose led to reduced total sleep by male but not female flies. (bournemouth.ac.uk)
  • I have studied sexually antagonistic genetic variation in fruit flies ( Drosophila melanogaster ) for a number of years, and have added a new study organism to my lab since I started working in Lund: the hermaphroditic flatworm Macrostomum lignano . (lu.se)
  • Drosophila simulans is a species of fly closely related to D. melanogaster, belonging to the same melanogaster species subgroup. (wikipedia.org)
  • Drosophila simulans was found later to be closely related to two island endemics, D. sechellia and D. mauritiana. (wikipedia.org)
  • Infections of Wolbachia, a commonly infectious strain of bacteria observed in many insects such as Trichogramma and Muscidifurax uniraptor wasps, are transmitted between generations of Drosophila simulans. (wikipedia.org)
  • Drosophila simulans has also played an important role in sequencing the genomes for certain Wolbachia strains. (wikipedia.org)
  • Seven mutant genes of Drosophila simulans have been shown to be allelomorphic to previously known mutant genes of D. melanogaster. (caltech.edu)
  • One species of Drosophila in particular, D. melanogaster , has been heavily used in research in genetics and is a common model organism in developmental biology . (wn.com)
  • Why are Drosophila melanogaster used in genetics? (greatgreenwedding.com)
  • The emphasis, in this essay, is on the development of sound basic approaches to the study of the genetics of man, with little attention to the numerous Utopian schemes that have always been so conspicuous in the literature of eugenics. (caltech.edu)
  • There is now in progress in several laboratories a comparative study of the genetics of the species of Drosophila. (caltech.edu)
  • In the presence of two sets of X-chromosome signal elements (XSEs), Sex-lethal (Sxl) is activated in female (XX) but not male (XY) animals. (greatgreenwedding.com)
  • If there is but one X chromosome in a diploid cell (1X:2A), the fly is male. (greatgreenwedding.com)
  • Under ordinary conditions there is so little crossing over in the fourth chromosome of Drosophila melanogaster that the usual method of constructing a map is not practicable. (caltech.edu)
  • part but not all of this influence is due to the Y-chromosome carried by such a male. (caltech.edu)
  • In a series of papers, Serebrovsky (1930), Dubinin (1929), Agol (1930) and their colleagues have described an extremely interesting group of bristle-reducing mutant genes lying at the scute locus of the X-chromosome of Drosophila melanogaster. (caltech.edu)
  • In September, 1913, a wild female Drosophila of a stock from Liverpool, Nova Scotia, was crossed to a male bearing the second chromosome mutant characters vestigial and speck. (caltech.edu)
  • This meant that males could have matching autosomes and Y chromosome with a mismatched X, or matching autosomes and X chromosome with a mismatched Y. For this specific experiment we picked eight of the novel genotypes, which have previously been shown to exhibit phenotypic differences, as well as their corresponding wild type populations for RNA pooled sequencing. (lu.se)
  • During the process of eclosion by which an adult fly emerges from the pupa, Drosophila exhibits regular locomotor activity (by vibration) that occurs during 8-10 hours intervals starting just before dawn. (wikipedia.org)
  • Drosophila male GSCs exhibit perturbations in nucleolar morphology with age. (elifesciences.org)
  • The anatomy of the germarium of the Drosophila ovariole is consistent with the existence of a niche that maintains the GSCs( Fig. 1A ). (biologists.com)
  • Specifically, yellow males were far less successful at mating than normal males, demonstrating for the first time that some behaviors had a genetic basis. (elifesciences.org)
  • One epithelial cell type in the adult male AGs, the secondary cell (SC), grows selectively in response to bone morphogenetic protein (BMP) signaling. (ox.ac.uk)
  • Tissue specificity of alternative splicing products of mouse mRNA encoding new protein hampin homologous to the Drosophila MSL-1 protein]. (nih.gov)
  • In Drosophila melanogaster, where sexual conflict over female mating rate is well established, we investigated how a common, non-lethal virus (sigma virus) might affect this conflict. (uky.edu)
  • Further studies are needed to demonstrate whether virus-induced changes in reproductive success affect male and female lifetime fitness, and whether virus-induced changes are under male, female, or viral control. (uky.edu)
  • The reciprocal cross produces sterile F1 males and no female progeny. (wikipedia.org)
  • Conclusions: Overall lipid compositions are similar between the sexes, although there are differences in saturation states of two lipid classes, where saturated fatty acids were male-biased and polyunsaturated fatty acids were female-biased. (usuhs.edu)
  • In Drosophila, male and female gametes begin development when a stem cell divides to produce a cyst precursor. (johnshopkins.edu)
  • McKearin, DM & Spradling, AC 1990, ' bag-of-marbles: A Drosophila gene required to initiate both male and female gametogenesis ', Genes & development , vol. 4, no. 12 B, pp. 2242-2251. (johnshopkins.edu)
  • The female is slightly larger than the male (Patterson, et al 1943). (greatgreenwedding.com)
  • Are female Drosophila bigger than males? (greatgreenwedding.com)
  • What is the difference between a male and female fruit fly? (greatgreenwedding.com)
  • However, the abdomen of the male fruit fly is shorter in contrast to that of the female fruit fly. (greatgreenwedding.com)
  • What makes a Drosophila male and what makes it a female? (greatgreenwedding.com)
  • An intriguing hypothesis therefore, is that female Drosophila are larger than males because elevated levels of insulin signaling increases growth rate. (greatgreenwedding.com)
  • What are three ways you can distinguish between male and female Drosophila? (greatgreenwedding.com)
  • The anatomy of male and female D. melanogaster varies in several ways. (greatgreenwedding.com)
  • How to tell the difference between male and female D.melanogaster? (greatgreenwedding.com)
  • Furthermore, the abdomen of the male fruit fly is rounded at the bottom while the abdomen of the female fruit fly is pointed at the bottom. (greatgreenwedding.com)
  • We tested here the effect of adult female nutrition on the response of female Drosophila melanogaster to a specific ejaculate component, the sex peptide (SP), which is of interest because of its effects on female egg laying, sexual receptivity, feeding rate, immune responses and potential role in mediating sexual conflict. (uea.ac.uk)
  • Male mating a second female after the first (male remating) is a common feature particularly in mass culture of Drosophila. (journalcra.com)
  • Female remating is not frequent as that of male remating, but yet it is reported in few species here we report that males of D.gangotri and D.nagarholensis, remounting the same female for second and subsequent times immediately after first mount. (journalcra.com)
  • Even during female remating, the repeated male mounting occurred. (journalcra.com)
  • Males of D.nagarholensis remounted the same female for three times, whereas D.gangotri mounted the same female twice, immediately after first mount. (journalcra.com)
  • He showed that in the female there was a considerable amount of crossing over between these two genes, but in the male there was none at all so far as the data showed. (caltech.edu)
  • Liver weights were increased in male rats exposed at 100ppm or higher and in all exposed female rats. (cdc.gov)
  • Different to the other D. willistoni strains maintained in the laboratory, the 17A2 strain spontaneously produced mutant males white-like (white eyes) and sepia-like (brown eyes) in stocks held at 17°C. In order to discover if this strain is potentially hypermutable, we submitted it to temperature stress tests. (scielo.br)
  • I have, however, never found a significant excess of male offspring unless the father was descended from certain of the older mutant stocks. (caltech.edu)
  • However, male infection did affect male reproductive success: first males sired a significantly greater proportion of offspring, as well as more total offspring, when they were infected with sigma virus. (uky.edu)
  • Viral reproductive success (the number of infected offspring) was strongly correlated with male reproductive success. (uky.edu)
  • Male reproductive glands secrete signals into seminal fluid to facilitate reproductive success. (ox.ac.uk)
  • We challenged males during development and either allowed them to recover or not in early adulthood, while measuring several determinants of male reproductive success. (authorea.com)
  • The nature of genetic variation for male sex traits continues to be an important unresolved issue in evolutionary biology. (mcmaster.ca)
  • The book's appendices include key aspects of Drosophila biology, essential solutions, buffers, and recipes. (cshlpress.com)
  • Male infection status did not influence time to copulation, or time to re-mating. (uky.edu)
  • Association learned as concerns partners for copulation in Drosophila melanogaster (Dukas, Clark & Abbott, 2006), and the choice of hosts for oviposition through colors learned by some Tephritidae genders (Papaj & Prokopy, 1989) and by Pieris brassicae (Smallegange, Everaarts & Van Loon, 2006) were already shown and can cause fitness intensification. (bvsalud.org)
  • Additionally, inbred males have elevated testicular oxidative stress which may underlie their reduced fertility. (wikipedia.org)
  • Here we investigate temperature induced changes in reproductive tissues and the fertility reduction in male Drosophila melanogaster. (authorea.com)
  • Correct completion of this histone to protamine switch (H-P switch) is essential to male fertility. (uni-marburg.de)
  • for example, some strains can protect against DCV (Drosophila C virus) while other strains cannot. (wikipedia.org)
  • Genetic studies showed several years ago that the third chromosomes of wild strains of Drosophila pseudoobscura often carry suppressors of crossing-over. (caltech.edu)
  • Drosophila serido was described in 1977 by VILELA & SENE, and in the following years populations of this species from several regions were studied by means of several genetic markers. (scielo.br)
  • To improve our understanding of these processes, we analysed the function of the mitotic checkpoint complex (MCC) component Bub3 and the nucleoporin Nup75, a component of the nuclear pore complex realizing the transport of signalling effector molecules to the nucleus, in the Drosophila testis . (bvsalud.org)
  • In this study, we introduced a light-driven proton transporter, Delta-rhodopsin (dR), to Drosophila mitochondria, where the mitochondrial proton-motive force (Δp) and mitochondrial membrane potential are maintained in a light-dependent manner. (nature.com)
  • Drosophila sechellia has significantly distinct mitochondrial DNA, further emphasizing the evolutionary differences between the three species. (wikipedia.org)
  • Mutants in the gene encoding the InsP 3 R ( itpr ) in Drosophila exhibit a range of defects including altered wing posture, increased spontaneous firing, and loss of rhythmic flight patterns in response to an air puff stimulus. (jneurosci.org)
  • Back-crossing to males from wild stocks or to males whose ancestry could be traced wholly to recently collected wild stocks has never resulted in significantly more than 50 per cent male offspring. (caltech.edu)
  • Since Rcd-1 is a regulator of differentiation in other species, it suggests that Rcd-1r may serve a similar role during spermatogonial differentiation in Drosophila . (plos.org)
  • Qualitative assessment of signal intensity in both treatment groups indicates that fit expression increased in mated male heads (panel C). (biomedcentral.com)
  • We show that homing in Drosophila responds to increased expression of HEGs specifically during the spermatogonia stage and this could be achieved through improved construct design. (plos.org)
  • Drosophila repleta Wollaston and D. neorepketa Patterson and Wheeler are closely similar species, the former widely distributed and the latter known from Guatemala. (caltech.edu)
  • Genetic studies in Drosophila have shown that CSP is critical for viability and regulated neurotransmitter release. (jneurosci.org)
  • Here we describe a method for rapid and accurate measurement of flight performance in Drosophila , enabling high-throughput screening. (jove.com)
  • Most species are within three major groups, the virilis-repleta radiation, the immigrans-tripunctata radiation and the Hawaiian Drosophila . (wn.com)
  • An evolution of Michael Ashburner's 1989 classic Drosophila: A Laboratory Manual, this book is an essential addition to the personal library of Drosophila investigators and an incomparable resource for other research groups with goals likely to require fly-based technical approaches. (cshlpress.com)