Major depression. Medical search. Frequent questions

The MDI differs from many other self-report inventories, such as the Beck Depression Inventory (BDI), because it is able to generate an ICD-10 or DSM-IV diagnosis of clinical depression in addition to an estimate of symptom severity. (wikipedia.org)
To ascertain how effective the Beck Depression Inventory for Primary Care (BDI-PC) was for differentiating medical inpatients who were and were not diagnosed with DSM-IV major depression disorders (MDD), this 7-item self-report instrument composed of cognitive and affective symptoms was administered to 50 medical inpatients along with the Depression subscale (HDS) from the Hospital Anxiety and Depression Scale (Zigmond & Snaith, 1983, Acta Psychiatrica Scandinavica, 67, 361-370). (nih.gov)
Patients were assessed at baseline using the HAM-D as the primary outcome assessment with the Beck Depression Inventory (BDI) and Clinical Global Impression Change (CGI/C) scores for secondary outcome measurements. (naturalmedicinejournal.com)
We evaluated 94 participants with MDD from the Beck Depression Inventory (BDI-II). (bvsalud.org)
The Beck Depression Inventory (BDI) is the most widely used self-rating scale, developed in 1961 by Aaron Beck based on symptoms he observed to be common among depressed patients. (medscape.com)

A diagnosis of major depressive disorder can be made if at least five of the following DSM criteria are met. (mentalhealth.com)
The severity of MDD, which was defined at the time of diagnosis by the self-rating Montgomery-Åsberg Depression Rating Scale, was identified as the most important prognostic factor for TRD (C index = 0.69). (medpagetoday.com)
The research of E. Redei is simple and valid enough so that anyone can easily get the test for depression which will provide "a scientific diagnosis in the same way someone is diagnosed with high blood pressure or high cholesterol" (as cited in Paul, 2014, n.p. (wepapers.com)
Based on claims submitted with a major depression diagnosis, 9 million people have that diagnosis in the United States. (phillyvoice.com)
According to the study, the overall depression diagnosis rate for all Blue Cross Blue Shield members increased by 33 percent. (phillyvoice.com)
For instance, it is not clear from the data, whether other chronic health conditions led to depression or if depression was the primary diagnosis and other chronic conditions came afterwards. (phillyvoice.com)
Major depression has a diagnosis rate of 4.4% for BCBS members. (managedhealthcareexecutive.com)
Members diagnosed with major depression use healthcare services more than those without a depression diagnosis. (managedhealthcareexecutive.com)
A general problem of reports on the effects of exercise on depression is the lack of information about the psychiatric diagnosis of participants according to standard references-for example, the Diagnostic and Statistic Manual of the American Society of Psychiatry (DSM IV). (bmj.com)
The PHQ-9 is a potentially valuable tool for diagnosis and management of depression because it can generate a diagnosis of major depression, as well a continuous score to monitor treatment. (annfammed.org)
Diagnosis of major depression was based on the Structured Clinical Interview for DSM-IV. (ucla.edu)
[ 4 ] An initial screen must be followed by a clinical interview to make the diagnosis of depression. (medscape.com)
To describe treatment patterns in patients with treatment -resistant depression (TRD) and major depressive disorder (MDD) stratified by depression severity and year of diagnosis . (bvsalud.org)
SSRIs and SNRIs were part of most combinations of treatment , regardless of depression severity, year of diagnosis , or presence of TRD. (bvsalud.org)
Irrespective of patient characteristics and year of diagnosis , SSRIs and SNRIs are the most used treatments for depression , even after patients met the criteria for TRD. (bvsalud.org)
On the other hand, the diagnosis of depression, post-traumatic stress disorder, HIV could be distressing enough to cause symptoms generalized anxiety disorder, alcohol and substance such as fear, depressed mood, feeling of guilt, abuse/dependence modules. (who.int)

Major depression is a common and complex disorder of gene-environment interactions. (nature.com)
The economic burden of adults with major depressive disorder in the United States (2010 and 2018). (nature.com)
Major depressive disorder (MDD) is a mood disorder characterized by a continuous low mood. (mentalhealth.com)
Situational depression, clinically known as adjustment disorder with depressed mood , is when an individual shows signs of depression following a stressful life event or circumstance. (mentalhealth.com)
At least 10% of people in the U.S. will experience major depressive disorder at some point in their lives. (stanford.edu)
How are major depression and bipolar disorder related? (stanford.edu)
We use the term bipolar disorder (or manic-depression) for this pattern. (stanford.edu)
Major depressive disorder and bipolar disorder are the two "major mood disorders. (stanford.edu)
Most people with major depression do not have close relatives with bipolar disorder, but the relatives of people with bipolar disorder are at increased risk of both major depression and bipolar disorder. (stanford.edu)
There are probably genetic changes that can increase the predisposition to both major depression and to certain anxiety disorders including generalized anxiety disorder, panic disorder and social phobia. (stanford.edu)
Researchers in Sweden found that 1 in 9 patients with unipolar major depressive disorder experienced an episode that fulfilled the criteria for treatment-resistant depression, a condition associated with greater rates of anxiety, stress, sleep disorders, and substance use disorder versus patients without TRD. (medpagetoday.com)
In this population-based, observational cohort study, Dr. Lundberg and his colleagues used data from the Stockholm Major Depressive Disorder (MDD) Cohort for episodes of MDD recorded between January 1, 2012, and December 31, 2017, that fulfilled the predefined criteria for TRD-at least three consecutive pharmacologic antidepressant treatments. (medpagetoday.com)
We used multivariate structural equation modeling to identify common genetic risk factors for major depression, generalized anxiety disorder, panic disorder, agoraphobia, social phobia and neuroticism (N) in a sample of 9270 adult subjects from the population-based Virginia Adult Twin Study of Psychiatric and Substance Use Disorders. (nature.com)
According to the authors of an invited article in Annual Review of Clinical Psychology , an urgent research goal for major depressive disorder (MDD) should be to advance understanding of the variable lifetime course of the disorder and to determine how to best predict whether someone will follow a clinical trajectory of recurrent or nonrecurrent depression. (medpagetoday.com)
esketamine, an enantiomer, has received FDA approval for rapid reduction in suicidal ideation in major depressive disorder (MDD). (psychiatrist.com)
Mr Blythe" is a 29-year-old AfricanAmerican male with a history of recurrent, sever major depressive disorder (MDD) without psychosis. (psychiatrictimes.com)
Participants with a major comorbid psychiatric disorder or suicide risk were excluded. (psychiatrictimes.com)
Major Depression (MD) is a common and debilitating psychiatric disorder, affecting about 7.5% of adolescents. (uni-muenchen.de)
Major depressive disorder - also known as clinical depression - is a mental disorder characterized by prolonged depressed mood and accompanied by a number of symptoms that interfere with normal human life. (wepapers.com)
Major Depressive Disorder is diagnosed by qualified mental health experts through interviewing, according to the criteria listed in the Diagnostic and Statistical Manual of Mental Disorders - DSM-5. (wepapers.com)
At 12 months, there was a statistically significant difference in the incidence of major depressive disorder between groups (11 percent in the mindfulness group compared to 27 percent in usual care). (medicalxpress.com)
These data indicate that persistent stress-system dysfunction in melancholic depression is independent of the conscious stress of the disorder. (biopsychiatry.com)
Thus, major depression and a Bipolar disorder are differently diagnosed. (differencebetween.net)
On the other hand, a Bipolar disorder was once considered as a manic depression. (differencebetween.net)
Major depressive disorder (MDD) is a psychiatric disease that affects 10-15% of people worldwide at least once in their lifetime ( Lépine and Briley, 2011 ). (frontiersin.org)
Rhodiola rosea versus sertraline for major depressive disorder: A randomized placebo-controlled trial. (naturalmedicinejournal.com)
Exclusions included severe major depression, bipolar disorder, substance abuse, dependence disorder, or primary anxiety at time of assessment. (naturalmedicinejournal.com)
Depression is a psychiatric disorder that is characterized by extreme feelings of sadness, anehedonia (or loss of pleasure), guilt, helplessness or hopelessness, an inability to concentrate, an increase or decrease of appetite, and thoughts of death. (dual-diagnosis.net)
Bipolar disorder is characterized by swift mood changes which range from mania or severe highs and depression or lows. (dual-diagnosis.net)
Persistent depressive disorder (PDD) is a long-term, chronic type of depression. (bridgestorecovery.com)
Persistent depressive disorder is a milder but more chronic and lasting form of depression. (bridgestorecovery.com)
Seasonal affective disorder causes depression in a seasonal pattern, most often in winter but in rare cases in spring and summer. (bridgestorecovery.com)
The clinical term depression most often refers to major depression, also known as major depressive disorder . (bridgestorecovery.com)
This study investigated the impact of recent life events & social adjustment on suicide attempter status in 34 patients with major depression, 24 patients with borderline personality disorder, & 22 patients with co-morbid major depression and borderline personality disorder. (suicideinfo.ca)
Major depression is a mood disorder characterized by depressive episodes and extreme feelings of sadness. (marijuanadoctors.com)
In the context of major depressive disorder (MDD), depersonalization symptoms are associated with greater depressive severity as indexed by treatment resistance, inpatient visits, and duration of depressive episodes. (diva-portal.org)
Our results indicate that depersonalization/derealization disorder symptoms in patients with depression are related to reduced functional connectivity between brain regions that are proposed to support processing of body-related (extrastriate body area) and autobiographical (DMN) information. (diva-portal.org)
Do genetic risk profiles for drug use disorder (DUD), major depression (MD), and attention-deficit hyperactivity disorder (ADHD) differ substantially as a function of sex, age at onset (AAO), recurrence, mode of ascertainment, and treatment? (lu.se)
article{761dc44d-9492-4dfa-8ca1-83dbd500559e, abstract = {{Do genetic risk profiles for drug use disorder (DUD), major depression (MD), and attention-deficit hyperactivity disorder (ADHD) differ substantially as a function of sex, age at onset (AAO), recurrence, mode of ascertainment, and treatment? (lu.se)
Major depressive disorder is a relatively common but severe illness associated with significant impairment in functioning. (family-institute.org)
Major depression is an episodic disorder - that is, individuals suffering from depression typically have one or more periods of depression (called episodes) that may fluctuate in duration or severity. (family-institute.org)
In Brazil, little is known about the maintenance of results after treatment of cognitive-behavioral therapy (CBT) for major depressive disorder (MDD). (bvsalud.org)
Major depressive disorder (MDD) is known for being a common clinical condition that generates a big economic impact on health policies due to its high prevalence and its debilitating nature (Greenberg, Fournier, Sisitsky, Pike, & Kessler, 2015). (bvsalud.org)
The antidepressant vortioxetine (Trintellix) improved cognition, memory, and depressive symptoms in patients with comorbid major depressive disorder (MDD) and dementia. (medscape.com)
Treatment patterns in patients with treatment-resistant depression in Danish patients with major depressive disorder. (bvsalud.org)
Major depression was the most common (11%) psychiatric disorder. (who.int)
Stress can lead to disorders such as major depression, chronic anxiety, and post-traumatic stress disorder (PTSD). (cdc.gov)
Bipolar I disorder is defined by the occurrence of mania, and yet 90% of people with this condition will experience depression. (medscape.com)
Depression Depression is a feeling of sadness and/or a decreased interest or pleasure in activities that becomes a disorder when it is intense enough to interfere with functioning. (msdmanuals.com)

In addition to depression, this technology has the potential for exploring the causes of a number of other disorders including chronic pain, obesity or even cancer. (kcl.ac.uk)
Dr Breen, jointly leading the Institute of Psychiatry at King's involvement, said: "We can now analyse millions of genetic variations in the human genome but it is only studies like that that will allows usto track down those that are important in disorders such as depression. (kcl.ac.uk)
But many common disorders like depression, diabetes and high blood pressure are also influenced by genes. (stanford.edu)
What about major depression and anxiety disorders? (stanford.edu)
Subject to confirmation in an independent sample, our study suggests that variations in the GAD1 gene may contribute to individual differences in N and impact susceptibility across a range of anxiety disorders and major depression. (nature.com)
Using a meta-analysis of data of the effectiveness of antidepressants, it has recently been shown that all antidepressants are more effective than placebo in adults with major depressive disorders [3]. (scirp.org)
Conclusions -Aerobic exercise can produce substantial improvement in mood in patients with major depressive disorders in a short time. (bmj.com)
These markers can be used not only to assist the development of new treatment compounds, but also for a personalized approach to treat patients with depression and related disorders by individual dose titration with an active medication, which targets this system. (karger.com)
As a result of depression, patient may have problems with sleep disorders, as well as with memory and a slowdown of psychomotor reactions. (happinessonline.org)
The Diagnostic and Statistical Manual of Mental Disorders ( DSM-5 ) criteria for major depression are reviewed below. (medscape.com)
Psychiatric disorders are common in PLWHA, with major depression being the commonest. (who.int)
Physical disorders, life experiences, and heredity can contribute to depression. (msdmanuals.com)

However, the syndrome reliability of depression itself-when you accumulate the symptoms we have just talked about, whereby the patient has at least five symptoms and at least one is depressed mood or anhedonia-was poor. (medscape.com)

PURPOSE Although screening for unipolar depression is controversial, it is potentially an efficient way to find undetected cases and improve diagnostic acumen. (annfammed.org)
Unipolar depression is second only to stroke as the leading cause of disability-adjusted life years. (annfammed.org)
In seven pages this paper examines various treatment approaches for adolescent major or unipolar depression. (echeat.com)

A psychological treatment known as behavioural activation can help prevent older people with mild symptoms of depression from developing more severe, clinical, depression, a study has found. (leeds.ac.uk)
The trial, called CASPER, involved 705 people aged 65 and older with mild symptoms of depression who were at high risk of becoming clinically depressed. (leeds.ac.uk)
Outpatients who showed symptoms of depression were recruited in the studies at the Department of Psychiatry of Showa University Northern Yokohama Hospital. (scirp.org)
When in the depressive phase, the individual can have all of the symptoms of depression. (dual-diagnosis.net)
The symptoms of depression most commonly affect an individual's mood and ability to handle daily activities , including sleeping and eating properly. (marijuanadoctors.com)
Getting regular exercise and following other healthy habits can give you an edge in fighting depression and often improves symptoms of depression. (medlineplus.gov)

According to the American Psychiatric Association ("Depression", n.d.), the most common treatments for MDD include antidepressants, psychotherapy, and electroconvulsive therapy (in cases when the patient is resistant to other medications). (wepapers.com)
Major depression is a psychiatric disease associated with physical inactivity, which in turn affects mental and physical health. (frontiersin.org)
Physically inactive, adult in-patients diagnosed with major depression were recruited from four Swiss psychiatric clinics between January 2019 and December 2020. (frontiersin.org)

Scientists have launched a groundbreaking £1.1M study into the causes of clinical depression.Depression will affect up to 25% of the population at some point in their lives. (kcl.ac.uk)
At the four-month follow-up, 17.2% of the Collaborative Care group had clinical depression, compared to 23.5% in the control group. (leeds.ac.uk)
Intensive, repetitive stress situations, trauma or loss of someone of something significant may also trigger the symptoms of the clinical depression. (wepapers.com)
Even though the majority of people face these symptoms from time to time, we can assume the fact of clinical depression if they last more than two weeks. (wepapers.com)
In 2014, the researchers from the Northwestern University of Chicago created the test to diagnose clinical depression based on nine levels of RNA biomarkers in the blood (Redei et al. (wepapers.com)
The most effective talk therapy for clinical depression is cognitive-behavioral or interpersonal psychotherapy. (wepapers.com)
In the test were involved 32 patients from Northwestern General Internal Medicine clinics aged from 21 to 79 years, who had previously been diagnosed with clinical depression by the usual method, and 32 not depressed control participants "matched by age, race and sex" (Redei et al. (wepapers.com)
1. Clinical depression occurs when there is already a disruption in the normal functioning and an individual displays inability to cope with depression. (differencebetween.net)
This scale is a commonly used method for objective measurement of clinical depression. (cdc.gov)

Now University of Aberdeen researchers have joined forces with the University of Liverpool and the Institute of Psychiatry, King's College London to try to find the genetic causes of depression.They believe the answers could lie with short DNA sequences which act as 'genetic switches' controlling key genes in an area of the brain that influences mood. (kcl.ac.uk)
Scientists at the Institute of Psychiatry at King's, led by Dr Gerome Breen and Professor Peter McGuffin, will look at common variations found in these sequences using DNA samples taken from thousands of patients with chronic depression. (kcl.ac.uk)
We were surprised to find a genetic risk overlap between cannabis dependence and major depression," said Dr. Joel Gelernter, the Foundations Fund Professor of Psychiatry, professor of genetics and of neuroscience, and senior author of the study. (scitechdaily.com)
five men, seven women) with a major depressive episode according to the Diagnostic and Statistical Manual of the American Society of Psychiatry (DSM IV) criteria participated. (bmj.com)

The investigators recruited adult outpatients aged 18 years or older with TRD, defined as a depressive episode without psychotic features, a Hamilton Depression Rating Scale (HAM-D) ≥ 18, and failure to respond to an adequate dose and duration (≥ 8 weeks) of 2 to 4 pharmacological treatments for the current episode, including their current SSRI. (psychiatrictimes.com)
GlobalData's clinical trial report, 'Psychotic Major Depression Global Clinical Trials Review, H2, 2015' provides an overview of Psychotic Major Depression clinical trials scenario. (clickpress.com)
This report provides top line data relating to the clinical trials on Psychotic Major Depression. (clickpress.com)
Psychotic depression is a severe episode of depression that causes delusions and hallucinations. (bridgestorecovery.com)

Major depression and situational depression are both mental health conditions characterized by persistent feelings of sadness and loss of interest in activities. (mentalhealth.com)
What is situational depression? (mentalhealth.com)
Major depression and situational depression share many of the same symptoms. (mentalhealth.com)
Mental health professionals also recognize other types of depression, such as situational depression, which occurs in response to a major life event, like a death. (bridgestorecovery.com)

Tropical Depression No. 15 formed in the Atlantic Ocean on Friday and is expected to become the fourth major hurricane of 2023. (scrippsnews.com)

Suicidal ideation (SI) was measured using the standard Hamilton Depression Rating Scale (HDRS) 5 suicide item (item 3) at 2 and 24 hours post-inhalation. (psychiatrist.com)
The Hamilton Depression Rating Scale is the most widely used interview scale, developed in 1960 to measure severity of depression in an inpatient population. (medscape.com)

To assess the information processing capabilities in 25 patients with primary fibromyalgia (FM) by comparing them with 22 patients with major depression and 18 healthy controls. (nih.gov)
It may not come as a surprise that treatment-resistant depression (TRD) is costly to patients. (medpagetoday.com)
The therapy, which carries a slight risk of seizures, is meant for patients with major treatment-resistant depression who do not respond to at least one medication. (inquirer.com)
Among patients experiencing first-onset depression, research has shown that some will have recurrences over their lifetime, while others will never experience another episode. (medpagetoday.com)
Two competing theories-stress sensitization and dual pathway models-may help elucidate which patients eventually experience additional bouts of depression. (medpagetoday.com)
Psilocybin has demonstrated antidepressant properties in patients with MDD and treatment-resistant depression ( TRD ). (psychiatrictimes.com)
Among primary care patients with subthreshold depression, mindfulness meditation training reduces the incidence of major depression and improves depression symptoms. (medicalxpress.com)
The authors suggest that, for patients with subthreshold depression who have not had a major depressive episode in the past six months, mindfulness training is a feasible method of preventing major depression . (medicalxpress.com)
Because norepinephrine (NE) and corticotropin-releasing hormone (CRH) can produce these physiological and behavioral changes, we measured the cerebrospinal fluid (CSF) levels each hour for 30 consecutive hours in controls and in patients with melancholic depression. (biopsychiatry.com)
In contrast to the significant negative correlation between plasma cortisol and CSF CRH levels seen in controls, patients with depression showed no statistical relationship between these parameters. (biopsychiatry.com)
No research has been done for the determination of plasma levels of tryptophan metabolites in patients of monopolar and bipolar depression. (scirp.org)
In patients of major monopolar depression age and gender differences of plasma levels of tryptophan metabolites disappear although significant differences are observed in healthy volunteers. (scirp.org)
Tomioka, H. , Masuda, J. , Takada, A. and Iwanami, A. (2020) Comparison of Age and Gender Differences of Tryptophan Metabolites in Patients of Major Monopolar and Bipolar Depression. (scirp.org)
Some people doubt roles of 5-HT in etiology of depression because 5-HT concentration was not decreased in the brains of depressive patients [4]. (scirp.org)
We analyzed plasma levels of patients of major monopolar depression and preliminarily reported that plasma levels of 5-HT, but not 5-HIAA, were lower in depressive patients [6]. (scirp.org)
However, since there are significant gender and age differences in plasma levels of TRP metabolites in healthy volunteers, we decided to analyze differences of TRP metabolites in patients of major monopolar depression and bipolar depression. (scirp.org)
The aim of this study was to find out whether data gathered before and during/after the lockdown among in-patients with major depression differ with regard to psychosocial health, physical activity and related attitudes and to establish whether baseline data have been affected by the lockdown. (frontiersin.org)
Baseline data gathered in in-patients suffering from major depression who are physically inactive upon admission to in-patient treatment in Switzerland seem to be unaffected by the COVID-19-induced lockdown. (frontiersin.org)
If patients were assessed to be at less than 50% reduction of the Hamilton Depression Rating (HAM-D) scale, the dosage was moved up to 2 capsules daily for weeks 3 and 4. (naturalmedicinejournal.com)
Objective -To evaluate the short term effects of a training programme on patients with moderate to severe major depression. (bmj.com)
For selected patients with moderate to severe major depression, aerobic exercise may result in a substantial improvement in symptoms in a short time. (bmj.com)
Major depression (MDE) does not only exert a profound effect on the quality of life, but also on the physical health of affected patients. (karger.com)
In particular, an increase in the plasma concentration of cortisol in patients with melancholic depression has consistently been reported. (karger.com)
METHODS Consecutive adult patients attending Auckland family practices completed the PHQ-9, after which they completed the Composite International Diagnostic Interview (CIDI) depression reference standard. (annfammed.org)
A PHQ-9 score of 10 or higher appears to detect more depressed patients than the originally described PHQ-9 scoring for major depression. (annfammed.org)
Patients with major depression may exhibit an endocannabinoid deficiency that causes them to feel heightened feelings of stress, sadness and anxiety. (marijuanadoctors.com)
In a study conducted by the University of Southern California, patients who smoked marijuana exhibited fewer signs of depression than nonusers. (marijuanadoctors.com)
Because patients with depression are seeking a way to regulate their moods, it's essential for them to find a form of marijuana that does not produce hallucinogenic effects. (marijuanadoctors.com)
The association between major depression and levels of soluble intercellular adhesion molecule 1, interleukin-6, and C-reactive protein in patients with recent acute coronary syndromes. (ucla.edu)
This study was conducted to determine whether or not depression is associated with higher levels of inflammatory markers in patients recovering from acute coronary syndromes. (ucla.edu)
The USPSTF published a level B recommendation for screening for depression in the general adult population (18 years and older), including older patients and pregnant and postpartum women. (medscape.com)
The study confirms earlier findings of improvement in both depressive symptoms and cognitive performance with vortioxetine in patients with depression and dementia and adds to this research that these clinical effects also extend to improvement in health-related quality of life and patients' daily functioning," Christensen said. (medscape.com)
It also demonstrates that patients with depression and comorbid dementia can be safely treated with 20 mg vortioxetine - starting dose of 5 mg for the first week and up-titration to 10 mg at day 8," he added. (medscape.com)
We further measured this outcome and found that 31% of patients reported new-onset depression and 75% of these had Center for Epidemiologic Studies Depression scores indicative of mild-to-severe depression. (cdc.gov)
A year after the outbreak of WNV in New York City, 38% of patients subjectively reported depression ( 4 ). (cdc.gov)
Another 1-year follow-up in Colorado noted that 23% of patients reported anxiety and depression ( 5 ). (cdc.gov)
We describe the subjective and objective evaluations of depression in these patients. (cdc.gov)
In all of these interviews, a higher than expected proportion of patients reported depression immediately after their illness. (cdc.gov)
In addition to the objective measurement using the CES-D scale, we also asked patients if they were experiencing depression since their illness and if they had a previous history of depression, with yes/no responses elicited. (cdc.gov)

A randomized controlled trial of adults with subthreshold depression compared a usual care group in which there was no psychological intervention (n=116) with a behavioral activation group focused on mindfulness training (n=115). (medicalxpress.com)
Treating Subthreshold Depression in Primary Care: A Randomized Controlled Trial of Behavioral Activation With Mindfulness, The Annals of Family Medicine (2018). (medicalxpress.com)

Distinguishing individuals who will have no or very few MDD recurrences from those who will have multiple episodes over their lifetimes "forces a reevaluation of almost everything presently believed about depression, from etiology through acute phase treatments and recurrence prevention, to questioning the utility of extant research on predicting and preventing recurrences," the authors wrote. (medpagetoday.com)
Serotonin, one of important metabolites of TRP has been implicated to play roles of patho-etiology of depression, there debates about roles of serotonin. (scirp.org)
As researchers continue to study the significance of the endocannabinoid system and its role in ensuring the body's daily functionality, studies are beginning to uncover the importance this system places in the etiology of depression. (marijuanadoctors.com)

5 The 9-item Patient Health Questionnaire (PHQ-9) 6 has been recommended for depression screening in primary care. (annfammed.org)

Another major health challenge was on my agenda in India - a challenge which will unfold into the 21st century and one which requires new methods - but the same determination and dedication. (who.int)

For the PHQ-9 a score of 10 or higher detected more cases of major depression than the PHQ determination of major depression originally described by Spitzer et al in 1999. (annfammed.org)

We hope to link differences in the switches that control these genes with susceptibility to distressing conditions such as depression and chronic anxiety. (kcl.ac.uk)
In addition, the Blue Cross Blue Shield report found that major depression diagnoses are often linked to other chronic health conditions. (phillyvoice.com)
Eighty-five percent of people who are diagnosed with major depression also have one or more serious chronic health conditions and, nearly 30 percent of these have four or more other health conditions. (phillyvoice.com)
It shows how major depression diagnoses are linked to other chronic health conditions. (managedhealthcareexecutive.com)
Chronic physical conditions and major depression are interrelated, as 85% of people who are diagnosed with major depression also have one or more serious chronic health conditions. (managedhealthcareexecutive.com)
Anyone with a chronic condition, such as heart disease or diabetes, should be aware about the strong link to major depression as a comorbidity and discuss with their provider available screening and possible treatment options should they be at risk. (managedhealthcareexecutive.com)
It is a chronic, long-term type of depression that lasts for at least two years. (bridgestorecovery.com)

Still, psychologists have different theories of what contributes to each type of depression. (mentalhealth.com)
Only when this happens that a professional is needed to diagnose and assess the type of depression the person has. (differencebetween.net)

Participants were also excluded if they were already undergoing antidepressant or herbal therapies or had other major illness that may affect mood or cognition. (naturalmedicinejournal.com)
Depression is a mental illness, a description of a mood, and a clinical term that encompasses several subtypes. (bridgestorecovery.com)
Depression can appear for a variety of reasons, including post-partum pregnancy, illness, abuse and genetics. (marijuanadoctors.com)

The situation is a little different if the parent or sibling has had depression more than once ("recurrent depression"), and if the depression started relatively early in life (childhood, teens or twenties). (stanford.edu)
Life stress and the long-term treatment course of recurrent depression: III. (family-institute.org)

Major depression diagnoses are skyrocketing in millennials and adolescents, according to a new study by the Blue Cross Blue Shield Association. (phillyvoice.com)
The study, " Major Depression: The Impact on Overall Health ," f ound a 47-percent increase in such diagnoses in millennials (ages 18 to 34) and a 63-percent increase in adolescents (ages 12 to 17) from 2013 to 2016. (phillyvoice.com)
Because the report is based on claims data, there is some limitations to what can be inferred from the surge in depression diagnoses. (phillyvoice.com)
Major depression diagnoses have risen, according to a study of medical claims by the Blue Cross Blue Shield Association. (managedhealthcareexecutive.com)
Substance abuse, other mental health diagnoses, and homelessness were identified as major risk factors. (cdc.gov)

Most people who suffer from depression do not have episodes of mania. (stanford.edu)
Research on predicting which individuals will experience MDD recurrence needs to start with the initial clinical episode of major depression, before multiple episodes occur, since recurrences and corresponding treatments confound comparisons. (medpagetoday.com)
Many people with dysthymia also experience major depressive episodes at some time in their lives. (dual-diagnosis.net)
Seasonal depression usually hits in the fall/winter time and is diagnosed if the individual has recurrent episodes, at least two times where they fall into depression and come out of it at the same time. (dual-diagnosis.net)
Major life events and major difficulties are differentially associated with history of major depressive episodes. (family-institute.org)

This could mean that in most cases of depression, around 50% of the cause is genetic, and around 50% is unrelated to genes (psychological or physical factors). (stanford.edu)
There are also atypical cases of depression that don't follow all the same patterns of other types. (bridgestorecovery.com)
For the PHQ-2 a score of 2 or higher detected more cases of depression than a score of 3 or higher. (annfammed.org)

One of the important points of the report is how many Americans are impacted by major depression," said Dr. Virgina Calega, a physician and vice president of medical management and policy for Independence Blue Cross. (phillyvoice.com)
Screening, prevention and treatment options for major depression should be openly discussed as a way to help de-stigmatize it," says Ginny Calega, vice president for medical management and policy, Independence Blue Cross. (managedhealthcareexecutive.com)

Any changes in these can cause imbalances in the amount of critical proteins in the brain that may increase susceptibility to depression.Unlike genes, little is known of these switches, technically known as enhancers, because up until now they have been very hard to find. (kcl.ac.uk)
Comparing the genomes of different species has helped them to identify the switches responsible for controlling genes known to be involved in depression, as well as addiction, obesity and inflammatory pain. (kcl.ac.uk)
How do we know that genes play a role in causing depression? (stanford.edu)
We don't yet know how many genes are involved in depression, but it is very doubtful that any one gene causes depression in any large number of people. (stanford.edu)
A new study links genes to marijuana dependence and major depression. (scitechdaily.com)

Major depression causes serious, persistent feelings of sadness and other symptoms that make functioning or enjoying life very difficult. (bridgestorecovery.com)

The median time from the start of a major depressive episode to TRD was 552 days, and selective serotonin reuptake inhibitors were the most common class of antidepressant treatment in all treatment steps. (medpagetoday.com)
As a treatment, it has been very effective in major depression, which is where it has FDA approval. (inquirer.com)
In the present analysis, we examined N 2 O's ability to reduce suicidal ideation in a pooled secondary analysis of data from 3 crossover trials investigating N 2 O in subjects with treatment-resistant major depression (TRMD). (psychiatrist.com)
We postulate that alpha-noradrenergic blockade, CRH antagonists, and treatment with antiglucocorticoids may act at different loci, alone or in combination, in the treatment of major depression with melancholic features. (biopsychiatry.com)
Antidepressants are widely used for the treatment of major depression. (scirp.org)
But the study also raises important questions about whether trials on biologics-pharmaceutical or herbal-alone truly address the multiple layers of depression treatment. (naturalmedicinejournal.com)
ECT is a safe and effective treatment for severe depression. (medlineplus.gov)
Due to these characteristics, in the last decade, a substantial increase in the search for alternatives to the treatment of depression occurred, mainly on psychotherapeutic interventions. (bvsalud.org)
Among psychotherapeutic alternatives, cognitive behavioral therapy (CBT) is regarded as being the most suitable and the most researched for the treatment of depression in adults. (bvsalud.org)
In a meta-analysis carried out with 115 studies, which verified the effects of CBT compared to control groups, other psychotherapies, and pharmacologic intervention, it was shown that CBT is an effective treatment for depression in adults when compared to the control group (Cuijpers et al. (bvsalud.org)
Use of patient-administered screening tools has increased as a quick and reliable option in the first step of depression assessment or as a treatment monitor. (medscape.com)
Commenting for Medscape Medical News , Claire Sexton, DPhil, senior director of scientific programs and outreach at the Alzheimer's Association, said the study "reflects a valuable aspect of treatment research because of the close connection between depression and dementia. (medscape.com)

The analysis also suggests that the genetic risk for dependence on marijuana is associated with a higher inherited risk of major depression. (scitechdaily.com)

A second common problem with depression is that it is perhaps the most common comorbid condition in all of medicine. (medscape.com)

Doctors do not know exactly what causes depression, but chemical abnormalities in the brain are probably involved. (msdmanuals.com)

Some years ago, people have difficulty discerning between Major Depression and Manic Depression. (differencebetween.net)

Greenberg and colleagues reported estimates showing that the incremental economic burden of adults with depression in the US alone was $326 billion in 2018, 38 percent higher than in 2010. (nature.com)

Bipolar depression alternates with periods of mania, an elevated and dangerously high-energy mood. (bridgestorecovery.com)

Meta-analysis has shown that in cases of mild to moderate depression, pharmaceuticals generally do not work any better than placebo, 1 which boasts a 25%-to-30% effectiveness rate. (naturalmedicinejournal.com)

Nor it is clear why so many more millennials and adolescents are being diagnosed with major depression. (phillyvoice.com)
Depression includes a feeling of sadness (or, in children and adolescents, irritability), and/or loss of interest in activities. (msdmanuals.com)
For adolescents with depression, a combination of psychotherapy and antidepressants is usually most effective, but for younger children, psychotherapy alone is usually tried first. (msdmanuals.com)
Depression occurs in as many as 2% of children and 5% of adolescents. (msdmanuals.com)

According to the National Institute of Mental Health ("Depression", n.d.), at about 6.7% of US adults annually recorded cases of MDD. (wepapers.com)
Depression comes in many different varieties recognized by mental health professionals. (bridgestorecovery.com)
One way to look at the differences between these two types of depression is to see how mental health professionals diagnose them. (bridgestorecovery.com)

This new study funded by the Medical Research Council will allow them to build on their earlier work and also analyse common sequence differences found in the general population which can result in increased risk of developing depression. (kcl.ac.uk)
Neuroticism, major depression and gender: a population-based twin study. (nature.com)
The study indicates that training the brain to block out negative thoughts could improve symptoms of anxiety, depression, and PTSD. (medicaldaily.com)
A study reveals that those who suffer from depression have a smaller hippocampus than non-suffering individuals. (medicaldaily.com)
Outpatients of depression were recruited in this study. (scirp.org)
A total of 57 subjects with mild to moderate major depression (MDD) were recruited for this study. (naturalmedicinejournal.com)
This study pitting Rhodiola rosea against sertraline is consistent with a greater body of research that shows minimal but measurable effects for monotherapeutic approaches to mild and moderate depression. (naturalmedicinejournal.com)
Major depression is a combination of the symptoms listed above and the interference of these symptoms with the individual's ability to work, study, eat, sleep, and generally, just live an enjoyable and fully functioning life. (dual-diagnosis.net)
One study found that this herbal remedy worked no better than a sugar pill for treating major depression. (medlineplus.gov)
A study in Alsen, Louisiana, (9) revealed high levels of near-clinical anxiety and depression in an African-American community located near a hazardous waste facility. (cdc.gov)
One recent study (10) conducted in a California community following an evacuation because of a toxic railroad spill reported significantly higher levels of depression and anxiety syndromes in the evacuated population versus the control population. (cdc.gov)

Studies show that the procedure, called Transcranial Magnetic Stimulation (TMS), works better than sham treatments to reduce depression with few apparent side effects. (inquirer.com)

Another advantage is the ability to detect individual predisposition to another depression episode after the patient achieves remission. (wepapers.com)

All types of depression affect mood and the ability to function. (bridgestorecovery.com)

A disabling episode of depression may occur only once but usually occurs several times in a lifetime. (dual-diagnosis.net)
Perinatal and postpartum depression occurs during and after pregnancy and giving birth, and causes symptoms ranging from moderate to severe and potentially life-threatening. (bridgestorecovery.com)

The Major Depression Inventory (MDI) is a self-report mood questionnaire developed by the World Health Organization. (wikipedia.org)
Arabic version of the Major Depression Inventory as a diagnostic tool: reliability and concurrent and discriminant validity. (wikipedia.org)
Bech P, Rasmussen N-A, Olsen LR, Noerholm V, Abildgaard W. The sensitivity and specificity of the Major Depression Inventory, using the Present State Examination as the index of diagnostic validity. (wikipedia.org)
66: 159-164 PMID 11578668 Olsen LR, Jensen DV, Noerholm V, Martiny K, Bech P. The internal and external validity of the Major Depression Inventory in measuring severity of depressive states. (wikipedia.org)

The association between midlife living arrangement and psychiatrist-diagnosed depression in later life: who among your family members reduces the risk of depression? (nature.com)
For example, if one of your close family members has depression, your chance of also being a sufferer is three to four times the general population risk. (kcl.ac.uk)
Being depressed can also make health problems worse and older people with depression are at an increased risk of dying, the researchers added. (leeds.ac.uk)
We can also look at adoption studies, to see whether an adopted person's risk of depression is greater if a biological parent had depression. (stanford.edu)
There are probably many non-genetic factors that increase risk of depression, many of which are probably not yet known. (stanford.edu)
If someone has a family history of depression, are they at very high risk? (stanford.edu)
Participants who consumed nine or more portions of ultra-processed foods daily had a 49% increased risk of depression compared to those who consumed less than four portions a day. (medicaldaily.com)
Publication II addresses the role of polygenic risk scores (PRS) for depression, as well as experiences of maltreatment. (uni-muenchen.de)
Athletes can also be at risk of depression, especially in the situation of losing a competition or insufficient sports results. (happinessonline.org)
Depression is a known risk factor for dementia, including Alzheimer's disease, and those who have dementia may experience depression. (medscape.com)
Major risk and protective factors within the subgroups of homeless veterans and veterans who served in Iraq and Afghanistan were broadly similar to those in the general VA population. (cdc.gov)
About 7% of people are affected with depression annually, and there is somewhere around a 17% lifetime risk to perhaps as high as 1 in every 5 people. (medscape.com)

Anatomy15

Organisms1

Diseases18

Chemicals and Drugs37

Analytical, Diagnostic and Therapeutic Techniques and Equipment53

Psychiatry and Psychology91

Phenomena and Processes20

Disciplines and Occupations4

Anthropology, Education, Sociology and Social Phenomena14

Humanities6

Information Science7

Named Groups8

Health Care54

Geographicals5

Beck Depressio5

Diagnosis16

Disorder49

Disorders12

Depressed mood1

Unipolar3

Symptoms of depression6

Psychiatric3

Clinical depression9

Psychiatry4

Psychotic4

Situational Depression4

20231

Hamilton Depre2

Patients39

Subthreshold Depression2

Etiology3

Health Questionnaire1

Methods1

Score of 101

Chronic7

Type of depression2

Illness3

Recurrent depression2

Diagnoses5

Episodes5

Cases of depression3

Calega2

Genes5

Persistent feelings of sadness1

Treatment12

Genetic-risk1

Comorbid1

Causes depression1

Manic-depression1

20181

Bipolar depression1

Mild to moderate depression1

Adolescents4

Mental Health3

Study11

Treatments1

Predisposition1

Types of Depression1

Occurs2

Inventory4

Risk12