Tumor Necrosis Factor-alphaReceptors, Tumor Necrosis FactorReceptors, Tumor Necrosis Factor, Type IReceptors, Tumor Necrosis Factor, Type IIInterleukin-1CytokinesLipopolysaccharidesInterleukin-6Cells, CulturedNecrosisNF-kappa BRNA, MessengerInterferon-gammaMacrophagesCell LineLymphotoxin-alphaMice, Inbred C57BLMonocytesRecombinant ProteinsSignal TransductionGene Expression RegulationApoptosisInflammationMice, Inbred BALB CTumor Necrosis FactorsAntibodies, MonoclonalArthritis, RheumatoidReverse Transcriptase Polymerase Chain ReactionTransforming Growth Factor alphaInterleukin-10Molecular Sequence DataInterleukin-8Base SequenceGene ExpressionDose-Response Relationship, DrugMice, KnockoutTumor Necrosis Factor Decoy ReceptorsTime FactorsAntirheumatic AgentsAntigens, CDDisease Models, AnimalMacrophage ActivationUp-RegulationCell Line, TumorSynovial MembraneTumor Cells, CulturedTransfectionLeukocytes, MononuclearInterleukin-1betaEnzyme-Linked Immunosorbent AssayTranscription, GeneticMembrane GlycoproteinsBlotting, WesternDown-RegulationNeutrophilsInflammation MediatorsFibroblastsFlow CytometryEndotoxinsMacrophages, PeritonealPromoter Regions, GeneticCell SurvivalImmunohistochemistryDrug SynergismCell DivisionT-LymphocytesI-kappa B ProteinsAnti-Inflammatory AgentsEnzyme ActivationLiverPentoxifyllineBlotting, NorthernEndothelium, VascularNitric OxideMice, Inbred C3HI-kappa B KinaseKineticsInterleukin-12TNF Receptor-Associated Factor 2Transcription Factor RelAPolymerase Chain ReactionImmunoglobulin GIntercellular Adhesion Molecule-1Receptors, Cell SurfacePhosphorylationGranulocyte-Macrophage Colony-Stimulating FactorTumor Markers, BiologicalDNA PrimersAmino Acid SequenceRats, Sprague-DawleyTumor Necrosis Factor Receptor-Associated Peptides and ProteinsAntigens, CD14LungSpleenInterleukinsTNF-Related Apoptosis-Inducing Ligandp38 Mitogen-Activated Protein KinasesAntibodiesCell DifferentiationProtein Binding