AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsInformation ScienceHealth Care
Liver NeoplasmsLiver Neoplasms, ExperimentalLymphomaLymphoma, B-CellLymphoma, Non-HodgkinCarcinogensCarcinoma, HepatocellularRats, Inbred F344Lymphoma, T-CellLymphoma, Large B-Cell, DiffuseLymphoma, FollicularBurkitt LymphomaLiver DiseasesLymphoma, B-Cell, Marginal ZoneLiverLiver TransplantationLymphoma, Mantle-CellLymphoma, T-Cell, CutaneousLiver CirrhosisLymphoma, T-Cell, PeripheralLymphoma, AIDS-RelatedLymphoma, Large-Cell, AnaplasticMicrosomes, LiverLiver RegenerationFatty LiverHodgkin DiseaseNeoplasmsPancreatic NeoplasmsLymphoma, Large-Cell, ImmunoblasticSkin NeoplasmsLiver Function TestsMitochondria, LiverDrug-Induced Liver InjuryImmunohistochemistryVincristineNeoplasms, Cystic, Mucinous, and SerousNeoplasms, Multiple PrimaryAntibodies, Monoclonal, Murine-DerivedDNA, NeoplasmPrednisoneEye NeoplasmsNeoplasms, Second PrimaryTranslocation, GeneticNose NeoplasmsThymus NeoplasmsAntigens, CD20Liver ExtractsLiver CirculationTreatment OutcomeRetrospective StudiesLymphoma, Extranodal NK-T-CellPrognosisCyclophosphamideNeoplasm StagingDoxorubicinImmunophenotypingLiver Failure, AcuteAntineoplastic Combined Chemotherapy ProtocolsGastrointestinal NeoplasmsFatal OutcomeNeoplasm ProteinsChromosomes, Human, Pair 14Liver AbscessB-LymphocytesTumor Markers, BiologicalLiver Diseases, AlcoholicKidney NeoplasmsIntestinal NeoplasmsAntigens, CD30Neoplasms, ExperimentalCentral Nervous System NeoplasmsHerpesvirus 4, HumanAntibodies, MonoclonalParotid NeoplasmsChromosomes, Human, Pair 18HepatectomyThyroid NeoplasmsLung NeoplasmsMediastinal NeoplasmsTime FactorsAntigens, NeoplasmGene RearrangementHepatocytesNeoplasms, Radiation-InducedLymph NodesTomography, X-Ray ComputedMyeloproliferative DisordersSurvival RateProto-Oncogene Proteins c-bcl-6Polymerase Chain ReactionRNA, MessengerNeoplasms, Plasma CellStomach NeoplasmsAdenocarcinoma, MucinousSurvival AnalysisBase SequenceAntineoplastic AgentsCombined Modality TherapyHematologic NeoplasmsReed-Sternberg Cells
Cervical NeoplasmsTumorMalignantLeukemiaTumors and lymphomasMyeloproliferative neoplasmFollicularHepatocellular carcinomaLeukaemiasCausative agentCancerSolid tumorsInvasivenessBurkitt'sPancreasNodulesLymphoid tissuesGastrointestinalNeoplasticCancersDiagnosisLungKidneyGastricMiceAcuteAutoimmunePrimaryTractPatientsEpidemiologicalDisordersBenignBloodDuctalCentral nervouStudyCellDiseaseStudiesSignificantly
Cervical Neoplasms1
  • Towards an automated procedure for the quantitative cytological screening of cervical neoplasms. (bmj.com)
Tumor9
  • Lymphoma-dependent mortality was not significantly altered by maternal consumption of any of the diet and little effect on lung tumor burden in mice surviving to 10 months of age was observed. (nih.gov)
  • Methods: We analyzed the findings from a recent Pathology Working Group (PWG) review of RI procedures and tumor diagnoses, evaluated consistency of RI and other laboratory findings for chemicals identified by the RI as positive for lymphoma/leukemia, and examined evidence for a number of other issues raised regarding RI bioassays. (nih.gov)
  • Discussion: Although the PWG identified close agreement with RI diagnoses for most tumor types, it did not find close agreement for lymphoma/leukemia of the respiratory tract or for neoplasms of the inner ear and cranium. (nih.gov)
  • Therefore, patients with refractory advanced/metastatic HCC referred for experimental therapies, who had adequate tumor tissue available, had targeted next generation sequencing (NGS) of their tumor samples using the Illumina HiSeq 2000 platform (Foundation One, Foundation Medicine, MA) and their treatment outcomes were analyzed. (nih.gov)
  • 17. Intrathecal 131I-labeled antitenascin monoclonal antibody 81C6 treatment of patients with leptomeningeal neoplasms or primary brain tumor resection cavities with subarachnoid communication: phase I trial results. (nih.gov)
  • However, the fastest growing tumor is probably Burkitt's lymphoma, with a mean doubling time of less than 3 days. (allassignmenthelp.com)
  • The application of molecular biological techniques in the field of tumor virology, cytogenetic, and cell biology led to the discovery of the transforming genes of tumor viruses, the genes activated at the breakpoints of non-random chromosomal translocations of lymphomas and leukemia (Carlos and Harlan, 1994). (allassignmenthelp.com)
  • Traditional screening of tumor markers has low efficiency due to the long experimental period. (impactaging.com)
  • In patients with tumor fever, diseases commonly detected by 18 F-FDG PET include Hodgkin's disease and aggressive non-Hodgkin's lymphoma but also colorectal cancer and sarcoma. (snmjournals.org)
Malignant5
  • Glioblastoma multiforme is the most common malignant primary central nervous system neoplasm in adults. (hindawi.com)
  • 11) Malignant neoplasm. (who.int)
  • Cancer (malignant tumors or neoplasm) is a generic term for a large group of diseases that can affect any part of the body. (allassignmenthelp.com)
  • In malignant tumours, the high level of EGF correlates with the size and invasiveness of the neoplasm. (iiarjournals.org)
  • Despite the constant development of diagnostic methods and targeted treatments, malignant neoplasms continue to rank as one of the main causes of human and animal death. (iiarjournals.org)
Leukemia6
  • The European Food Safety Authority (EFSA) and others have suggested that study design and protocol differences between the RI and other laboratories by may contribute to controversy regarding cancer hazard findings, principally findings on lymphoma/leukemia diagnoses. (nih.gov)
  • Conclusions: We concluded that a ) issues related to respiratory tract infections have complicated diagnoses at that site (i.e., lymphoma/leukemia), as well as for neoplasms of the inner ear and cranium, and b ) there is consistency and value in RI studies for identification of other chemical-related neoplasia. (nih.gov)
  • Leukemia and Lymphoma. (tau.ac.il)
  • T-cell lymphoma in a savanna monkey (Cercopithecus aethiops) probably related to simian T-cell leukemia virus infection. (lookformedical.com)
  • The neoplastic cells, which were highly pleomorphic, resembled those in adult T-cell lymphoma-leukemia in humans. (lookformedical.com)
  • This virus serologically cross-reacts with simian T-cell leukemia virus, which may be the causative agent of the present neoplasm. (lookformedical.com)
Tumors and lymphomas2
  • Cyclophosphamide (CPO) is an alkylating cytotoxic agent that has been effectively used in patients for the last century for the curing of neoplastic maladies, such as solid tumors and lymphomas, as well as non-neoplastic maladies, such as rheumatoid arthritis and systemic lupus erythrematosus [ 1 ]. (biomedcentral.com)
  • Compared with other mouse strains, the observed incidences of tumors in FVB/N mice suggest a higher than usual rate of lung tumors and a lower than usual incidence of liver tumors and lymphomas. (jax.org)
Myeloproliferative neoplasm1
  • The sessions I found most beneficial were the myeloproliferative neoplasm (MPN) and the myeloma ones. (b-s-h.org.uk)
Follicular2
  • Overexpression of bcl-2 proteins , due to a translocation of the gene, is associated with follicular lymphoma. (lookformedical.com)
  • Fakan F, Boudov L, Sk lov A. [Immunohistochemical detection of follicular dendritic cells in the diagnosis of small B-cell lymphomas]. (patologie.cz)
Hepatocellular carcinoma1
  • Nonalcoholic steatohepatitis (NASH) is an advanced form of NAFLD can progress to liver cirrhosis and hepatocellular carcinoma (HCC). (bvsalud.org)
Leukaemias1
  • The haematological neoplasms originate by the myeloid or the lymphoid cell lines, historically named leukaemias or lymphomas, based on the prevalent location in the blood or the lymph nodes, respectively. (hindawi.com)
Causative agent1
  • Our experiments began with the study of the fundamental mechanisms by which Epstein-Barr Virus (EPV), an important causative agent of lymphomas, Hodgkin's Disease and Naso-pharyngeal carcinoma, uniquely and efficiently causes the uncontrolled proliferation and survival of normal human B lymphocytes. (nih.gov)
Cancer7
  • We have previously documented that a single dose of 15 mg/Kg DBP to pregnant mice late in gestation (GD 17) produces an aggressive T-cell lymphoma as well as lung and liver cancer in offspring. (nih.gov)
  • Agency (EPA) (IRIS 2010), and International Agency for Research on Cancer (IARC 2019) concluded that the data suggested an association between pentachlorophenol exposure and increased risk of non-Hodgkin lymphoma based on the consistent findings across epidemiological studies. (cdc.gov)
  • Polyamines in colorectal cancer--a clinical and experimental approach. (bmj.com)
  • The most common causes of cancer death are cancers of lung (1.59 million deaths), liver (745 000 deaths), stomach (723 000 deaths), colorectal (694 000 deaths), breast (521 000 deaths) and esophageal cancer (400 000 deaths) (Cancer, 2015). (allassignmenthelp.com)
  • The National Cancer Institute nominated phenolphthalein for study because of its widespread use as a component in numerous laxative preparations and the lack of adequate testing for carcinogenicity in experimental animals. (nih.gov)
  • This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. (cancerindex.org)
  • In particular, the RNA sequencing gene expression experimental technique stands out for case-control studies on cancer, which can be addressed with supervised machine learning techniques able to extract human interpretable models composed of genes, and their relation to the investigated disease. (biomedcentral.com)
Solid tumors2
  • This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have progressed following at least one line of standard treatment or for which no agreed upon treatment approach exists. (ucdavis.edu)
  • Identifying these genetic abnormalities first may help doctors plan better treatment for patients with solid tumors, lymphomas, or multiple myeloma . (ucdavis.edu)
Invasiveness1
  • Liver biopsy remains the gold standard, but it has several issues that must be addressed, including its invasiveness, cost, and inter-observer diagnosis variability. (bvsalud.org)
Burkitt's1
  • 11. Therapy with unlabeled and 131I-labeled pan-B-cell monoclonal antibodies in nude mice bearing Raji Burkitt's lymphoma xenografts. (nih.gov)
Pancreas3
  • The systemic nature of TDI carcinogenicity was demonstrated by the appearance of tumors at multiple sites (pancreas, liver, skin, mammary glands, and circulatory system). (cdc.gov)
  • The presence of infectivity and PrP res in inflamed liver, pancreas, and kidney tissues has been recently observed in transgenic and spontaneous mouse models of chronic inflammation on infection with the Rocky Mountain Laboratory strain of scrapie ( 6 ), and PrP res has been shown in mammary glands of scrapie-infected sheep with mastitis ( 7 ). (cdc.gov)
  • However, there have been reported rare cases in the gallbladder, pancreas, liver and urinary bladder. (biomedcentral.com)
Nodules1
  • Boudov L, Torlakovic E, Delabie J, Reimer P, Pfistner B, Wiedenmann S, Diehl V, M ller-Hermelink HK, R diger T. Nodular lymphocyte-predominant Hodgkin lymphoma with nodules resembling T-cell/histiocyte-rich B-cell lymphoma:differential diagnosis between nodular lymphocyte-predominant Hodgkin lymphoma and T-cell/histiocyte-rich B-cell lymphoma. (patologie.cz)
Lymphoid tissues2
  • Afterwards, more than 70 nosological entities were identified, classified according to the 2008 World Health Organization (WHO) classification of neoplasms of the hematopoietic and lymphoid tissues, on the basis of the recognition of distinctive features in terms of morphology, clinical picture, immunophenotype, and genetic and molecular characteristics [ 68 ]. (hindawi.com)
  • Boudov L, Vanecek T, S ma R, Bouda J, Hes O, Fakan F. [Role of p27Kip1 protein in the cell cycle and its appearance in lymphoid tissues, particularly non-Hodgkin's B-cell lymphomas. (patologie.cz)
Gastrointestinal3
  • Systemic mastocytosis, often termed systemic mast cell disease (SMCD), is characterized by infiltration of clonally derived mast cells in different tissues, including bone marrow (see the image below), skin, the gastrointestinal (GI) tract, the liver, and the spleen. (medscape.com)
  • AIDS-KS is characterized by dermal lesions but may progress and result in visceral involvement in the gastrointestinal tract, lungs, and liver. (nih.gov)
  • The term was first coined by Mazur and Clark, in 1983, in order to describe a heterogeneous group of gastrointestinal non-epithelial neoplasms. (biomedcentral.com)
Neoplastic2
  • RESEARCH OBJECTIVES Background Patients infected with the human immunodeficiency virus (HIV) are at high risk for the development of opportunistic infections and neoplastic sequelae, particularly Kaposi's sarcoma (KS) and lymphoproliferative diseases such as non-Hodgkin's lymphomas (NHL). (nih.gov)
  • The Experimental Therapeutics (ET) Program contributes to more effective treatment of neoplastic diseases through a spectrum of basic and translational research. (grantome.com)
Cancers2
  • To evaluate the proportion of patients with objective response (OR) to targeted study agent(s) in patients with advanced refractory cancers/lymphomas/multiple myeloma. (ucdavis.edu)
  • To evaluate the proportion of patients alive and progression free at 6 months of treatment with targeted study agent in patients with advanced refractory cancers/lymphomas/multiple myeloma. (ucdavis.edu)
Diagnosis2
  • Dysmyelopoiesis - Signs of myelodysplasia or myeloproliferation in non-mast cell lineage(s) but insufficient criteria for definitive diagnosis of an associated hematologic neoplasm , with the blood picture normal or only slightly abnormal. (medscape.com)
  • We analysed the whole SSc patients' cohort, recruited in our Rheumatology Centre, including 454 cases referred to our university-based hospital from 1 January 2003 to 31 December 2016, in order to find the patients who presented haematological neoplasms in their clinical history, after SSc diagnosis. (hindawi.com)
Lung2
  • Experimental Lung Research. (wikipedia.org)
  • All tumors in males and most in females at this time were alveolar-bronchiolar (AB) neoplasms of the lung. (jax.org)
Kidney4
  • 8) Concomitant chronic disease such as chronic renal failure (CKD), nephrotic syndrome, acute or chronic liver disease, chronic obstructive pulmonary disease (COPD), decompensated ischemic heart disease, hypertensive encephalopathy, cerebrovascular disease (CVA), diabetes mellitus with metabolic decompensation, arterial insufficiency acute peripheral and complications in other organs such as kidney (Kinmestiel - Wilson, Necrotizing papillitis). (who.int)
  • In kidney, liver, and heart transplant patients Cyclosporine Capsules USP MODIFIED may be administered with other immunosuppressive agents. (nih.gov)
  • Kidney, liver, and heart transplantation: Neoral (Cyclosporine) is indicated for the prophylaxis of organ rejection in kidney, liver, and heart allogeneic transplants. (nmdpresearch.org)
  • With a marked diminish in liver and kidney function biomarkers. (biomedcentral.com)
Gastric1
  • It induces epidermal keratosis and proliferation, multiplication and differentiation of pulmonary alveolar epithelium, facilitates corneal epithelium regeneration, causes hypertrophy and hyperplasia of liver cells, inhibits the secretion of gastric juice, retards ovary development and hair growth ( 7 ). (iiarjournals.org)
Mice4
  • When rats and mice were exposed orally to TDA, tumors were induced in the livers, skin, and mammary glands of both species. (cdc.gov)
  • Lymphoreticular accumulation of infectivity and PrP res occur early after scrapie infection in sheep and in various experimental animal models of transmissible spongiform encephalopathies, including mice infected with the vCJD agent ( 5 ). (cdc.gov)
  • Experimental studies in mice were approved by the institutional animal care and use committee of the American Red Cross Holland Laboratory. (cdc.gov)
  • The biological activity of glatiramer acetate is determined by its ability to block the induction of experimental autoimmune encephalomyelitis (EAE) in mice. (rxlist.com)
Acute1
  • Lymphoma-like presentation of acute monocytic leukaemia. (bmj.com)
Autoimmune1
  • Most patients with FUO have autoimmune or collagen vascular disease or a neoplasm-responsible for up to 54% of all cases. (snmjournals.org)
Primary1
  • Glioblastoma multiforme (GBM) is a common primary central nervous system (CNS) neoplasm in adults with a very aggressive natural history and grim prognosis [ 1 , 2 ]. (hindawi.com)
Tract2
  • Bile is produced by the liver and is channeled by the biliary ductal system into the intestinal tract for the emulsification and absorption of fats. (medscape.com)
  • GISTs are a subset of mesenchymal tumors and represent the most common mesenchymal neoplasms of GI tract. (biomedcentral.com)
Patients3
  • Detection of immunoglobulins G and A on the cell membrane of hepatocytes from patients with alcoholic liver disease. (bmj.com)
  • Increased susceptibility to infection and the possible development of lymphoma and other neoplasms may result from the increase in the degree of immunosuppression in transplant patients. (nih.gov)
  • Often patients will be randomized between an established 'standard' treatment and a new 'experimental' treatment - it is not known which is the better treatment. (mthelpinghand.com)
Epidemiological1
  • Supporting activities include the development of epidemiological, experimental laboratory, and risk-assessment methods that could produce internationally comparable results, and the development of manpower in the field of toxicology. (inchem.org)
Disorders1
Benign2
  • Preclinical studies showed the development of benign liver tumors in rats treated with extremely high doses of the drug for prolonged periods. (nih.gov)
  • Following these guidelines will eliminate from consideration most short-lived viral pyrexias and other benign transient causes of fever. (snmjournals.org)
Blood1
  • In these lights, the known association between SSc and haematological malignancies should be better characterized, especially as regards eventual associations between SSc features and specific type of blood neoplasms. (hindawi.com)
Ductal1
  • In a patient with persistent elevation of liver-associated enzymes, the contrast medium entering the biliary ductal system preferentially enters the cystic duct. (medscape.com)
Central nervou1
  • The drug does not enter the central nervous system in experimental animals in significant amounts, and it does not affect CNS function in man. (nih.gov)
Study1
  • Middle Eastern intestinal lymphoma: a morphological and immunohistochemical study. (bmj.com)
Cell1
  • Fakan F, Chlumsk A, Krijt J, Kocov L. Cytoplasmic liver cell inclusions--atypical feature of porphyria cutanea tarda--are absent in porphyria-related hepatic neoplasias. (patologie.cz)
Disease2
  • Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease. (bvsalud.org)
  • Chlumsk A, Cur k R, Boudov L, Mukensnabl P, Klvana P. Chlorpromazine-induced cholestatic liver disease with ductopenia. (patologie.cz)
Studies3
  • Experimental studies in animals have demonstrated that toluene diisocyanate (TDI) is a carcinogen. (cdc.gov)
  • Experimental studies in animals have also demonstrated that 2,4-toluenediamine (TDA), a hydrolysis product of 2,4-TDI, is a carcinogen. (cdc.gov)
  • The initial experimental studies of carcinogenesis were conducted in animals. (cancerquest.org)
Significantly1
  • Absolute and relative liver weights of 25,000 and 50,000 ppm males were significantly greater than those of the controls. (nih.gov)