AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and Equipment
Histiocytic SarcomaHistiocytic Disorders, MalignantSarcomaLymphomaHistiocytesHyalinSplenic NeoplasmsDog DiseasesLymphoma, B-CellSarcoma, ExperimentalLymphoma, Non-HodgkinLymphoma, T-CellAntigens, Differentiation, MyelomonocyticLymphoma, Large B-Cell, DiffuseDogsMuramidaseSarcoma, EwingLymphoma, FollicularSarcoma, KaposiSarcoma, Synovial
TumorsNeoplasmsHemangiosarcomaLangerhansHistiocytosisCancersHodgkinTumorSmall lymphocyDisordersReticulumFollicular lymphomasLymphocyticCarcinomaMediastinalIndolentInterdigitatingLymphoproliferative DiseasesHigher incidence of lymphomaLymph nodesCancerNodular lymphomaProliferationCellKaposiPCNSLLymphoblasticClassificationClinical TrialsHodgkin'sDisease
Tumors10
  • PCNSL occurs at an incidence of 0.47 per 100,000 person-years, accounting for 4%-6% of extranodal lymphomas and 4% of newly diagnosed CNS tumors. (medscape.com)
  • Interestingly, these tumors exhibited characteristics of transdifferentiation and acquired expression of histiocytic/dendritic cell markers. (jci.org)
  • This phase II Pediatric MATCH trial studies how well ensartinib works in treating patients with solid tumors, non-Hodgkin lymphoma, or histiocytic disorders with ALK or ROS1 genomic alterations that have come back (recurrent) or does not respond to treatment (refractory) and may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced). (ucsf.edu)
  • This phase II Pediatric MATCH trial studies how well ivosidenib works in treating patients with solid tumors that have spread to other places in the body (advanced), lymphoma, or histiocytic disorders that have IDH1 genetic alterations (mutations). (ucsf.edu)
  • This phase II pediatric MATCH treatment trial studies how well selpercatinib works in treating patients with solid tumors that may have spread from where they first started to nearby tissue, lymph nodes, or distant parts of the body (advanced), lymphomas, or histiocytic disorders that have activating RET gene alterations. (ucsf.edu)
  • This Pediatric MATCH screening and multi-sub-study phase II trial studies how well treatment that is directed by genetic testing works in pediatric patients with solid tumors, non-Hodgkin lymphomas, or histiocytic disorders that have progressed following at least one line of standard systemic therapy and/or for which no standard treatment exists that has been shown to prolong survival. (ucsf.edu)
  • Patients with genetic changes or abnormalities (mutations) may benefit more from treatment which targets their tumor's particular genetic mutation, and may help doctors plan better treatment for patients with solid tumors or non-Hodgkin lymphomas. (ucsf.edu)
  • Unfortunately, they have a short life expectancy and are more likely to develop cancers such as mast cell tumors and malignant histiocytosis (histiocytic sarcomas). (vmsg.com)
  • However, when it comes to cancer they have a higher than average risk of developing a number of different cancers including soft tissue sarcomas, osteosarcoma (bone cancer), lymphoma, mast cell tumors, transitional cell carcinomas (bladder cancer) and hemangiosarcomas (cancer of the blood vessels). (vmsg.com)
  • reticulum cell sarcomas, cutaneous nodular amyloidosis) are relatively common cutaneous tumors. (merckvetmanual.com)
Neoplasms1
Hemangiosarcoma3
Langerhans2
  • [ 5 , 6 ] Although several histiocytic disorders are briefly discussed in this article (see History ), the primary focus is on Langerhans cell histiocytosis. (medscape.com)
  • Recently, transformation of CLL into histiocytic/dendritic/Langerhans cell sarcoma (all are myeloid origin), dubbed as "transdifferentiation", has also been reported. (najms.com)
Histiocytosis2
  • CD68 is expressed by interdigitating reticulum cells in tonsil and some histiocytic lymphoma or histiocytosis, acute myeloid leukemia (AML), and granulocytic sarcoma. (thermofisher.com)
  • We report a rather peculiar case of cutaneous T cell lymphoma with pathological features simulating malignant histiocytosis. (tau.ac.il)
Cancers3
  • Lymphoma is any of a diverse group of cancers that originate in lymphocytes of the lymphatic system , a secondary (but open) circulatory system in vertebrates . (newworldencyclopedia.org)
  • It is those cancers that originate in the lymphatic system that are referred to as lymphomas. (newworldencyclopedia.org)
  • Non-Hodgkin's Lymphoma is actually a collection of many different lymph cancers. (ecureme.com)
Hodgkin10
  • Lymphoma commonly is categorized broadly as Hodgkin's lymphoma (HL) and non-Hodgkin lymphoma (NHL, all other types of lymphoma). (newworldencyclopedia.org)
  • Hodgkin lymphoma, as well as other minor groups. (newworldencyclopedia.org)
  • Also see Non-Hodgkin Lymphoma . (medscape.com)
  • Expert Consensus on the prevention and treatment of indolent B-cell non-Hodgkin lymphoma with novel coronavirus infection]. (bvsalud.org)
  • Indolent B-cell non-Hodgkin lymphoma (B-iNHL) is a group of mature B-cell lymphomas that develop slowly. (bvsalud.org)
  • Richter's Transformation of chronic lymphocytic leukemia (CLL) to diffuse large B-cell lymphoma or Hodgkin lymphoma (both are B-cell origin) are well described in literature. (najms.com)
  • Bockorny B, Codreanu I Dasanu CA. Hodgkin lymphoma as Richter transformation in chronic lymphocytic leukaemia: a retrospective analysis of world literature. (najms.com)
  • Michelis FV, Kourti G, Skertsou M. Richter transformation of chronic lymphocytic leukemia into composite diffuse large B-cell and Hodgkin lymphoma. (najms.com)
  • IgVH mutational status and clonality analysis of Richter's transformation: diffuse large B-cell lymphoma and Hodgkin lymphoma in association with B-cell chronic lymphocytic leukemia (B-CLL) represent 2 different pathways of disease evolution. (najms.com)
  • non-Hodgkin lymphoma, other and unspecified types (C85. (who.int)
Tumor5
  • This classification attempts to classify lymphomas by cell type (i.e. the normal cell type that most closely resembles the tumor). (newworldencyclopedia.org)
  • PURPOSE: This is a 2-part study of pembrolizumab (MK-3475) in pediatric participants who have either advanced melanoma or a programmed cell death ligand 1 (PD-L1)-positive advanced, relapsed or refractory solid tumor or lymphoma. (cincinnatichildrens.org)
  • Using an A20 transplantable lymphoma model, we found that the CSP-STAT3 siRNA conjugate significantly inhibited tumor growth and weight. (bvsalud.org)
  • These findings indicate that specifically targeting STAT3 siRNA to B cell lymphoma cell lines can significantly decrease STAT3 activity and inhibit tumor progression in vitro and in vivo, suggesting its potential utilization for cancer treatment. (bvsalud.org)
  • The main differentials for this mass lesion include meningioma, histiocytic sarcoma, granular cell tumor and lymphoma, with meningioma being the most common possibility. (hallmarq.net)
Small lymphocy2
  • Transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma to interdigitating dendritic cell sarcoma: Evidence for transdifferentiation of the lymphoma clone. (najms.com)
  • Shao H, Xi L, Raffeld M, Feldman AL, Ketterling RP, Knudson R. Clonally related histiocytic/dendritic cell sarcoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: A study of seven cases. (najms.com)
Disorders2
  • Over the last several decades, the nomenclature used to describe histiocytic disorders has substantially changed to reflect the wide range of clinical manifestations and the variable clinical severities of some disorders that have the same pathologic findings. (medscape.com)
  • Improved understanding of the pathology of histiocytic disorders requires knowledge of the origins, biology, and physiology of the cells involved. (medscape.com)
Reticulum1
  • Primary central nervous system lymphoma (PCNSL) has been known by many other names, including reticulum cell sarcoma, diffuse histiocytic lymphoma, and microglioma. (medscape.com)
Follicular lymphomas2
  • These transformed follicular lymphomas (t-FL) are essentially incurable. (wikipedia.org)
  • Feldman AL, Arber DA, Pittaluga S, Martinez A, Burke JS, Raffeld M. Clonally related follicular lymphomas and histiocytic/dendritic cell sarcomas: Evidence for transdifferentiation of the follicular lymphoma clone. (najms.com)
Lymphocytic1
  • [ 6 ] Additionally, a biopsy of lymphoma pre-treated with corticosteroids may reveal only gliosis or lymphocytic and histiocytic infiltrates without identifiable neoplastic cells. (medscape.com)
Carcinoma1
  • Quinoline administered by intraperitoneal injection in CD-1 mice induced lymphoma in females and hepatocellular carcinoma in males. (cdc.gov)
Mediastinal1
  • Nasal cavity sarcoma, nasal esthesioneuroepithelioma, and mediastinal sarcoma were increased in male rats. (cdc.gov)
Indolent2
  • the remaining 10% are T-cell, mantle cell, Burkitt, or indolent B-cell lymphomas. (medscape.com)
  • Wang E, Hutchinson CB, Huang Q, Sebastian S, Rehder C, Kanaly A. Histiocytic sarcoma arising in indolent small b-cell lymphoma: Report of two cases with molecular/genetic evidence suggestive of a 'transdifferentiation' during the clonal evolution. (najms.com)
Interdigitating2
  • Interdigitating dendritic cell sarcoma subtotally replacing lymph node shows that the neoplasm tends to spare lymphoid follicles. (basicmedicalkey.com)
  • Interdigitating dendritic cell sarcoma involving lymph node shows that the neoplastic cells are spindled and epithelioid with abundant eosinophilic cytoplasm. (basicmedicalkey.com)
Lymphoproliferative Diseases1
  • Kaposi sarcoma herpesvirus (KSHV) is specifically associated with Kaposi sarcoma (KS) and 2 B cell lymphoproliferative diseases, namely primary effusion lymphoma (PEL) and multicentric Castleman disease (MCD). (jci.org)
Higher incidence of lymphoma2
  • Because the lymphatic system is part of the body's immune system , patients with weakened immune system, such as from HIV infection or from certain drugs or medication, also have a higher incidence of lymphoma. (newworldencyclopedia.org)
  • Standard Poodles, Golden Retrievers and Australian Shepherds are a few of the breeds with higher incidence of lymphoma. (newportharborvets.com)
Lymph nodes2
  • Generalized reticular cell sarcoma of lymph nodes associated with lymphatic leukemia. (najms.com)
  • Occasionally, lymphoma can affect lymph nodes that are not visible from outside the body, such as those inside the chest or in the abdomen. (newportharborvets.com)
Cancer6
  • According to the U.S. National Institutes of Health, lymphomas account for about five percent of all cases of cancer in the United States. (newworldencyclopedia.org)
  • Hodgkin's lymphoma accounts for less than one percent of all cases of cancer in the United States. (newworldencyclopedia.org)
  • Follicular lymphoma (FL) is a cancer that involves certain types of white blood cells known as lymphocytes. (wikipedia.org)
  • However, each year 2-3% of FL cases progress to a highly aggressive form often termed stage 3B FL, to an aggressive diffuse large B-cell lymphoma, or to another type of aggressive B-cell cancer. (wikipedia.org)
  • Unfortunately, Bernese Mountain Dogs do have a relatively high rate of cancer in comparison to other breeds, including mast cell tumours, lymphoma, and histiocytic sarcoma. (petinsuranceaustralia.com.au)
  • Lymphoma is a cancer of the lymph glands. (ecureme.com)
Nodular lymphoma1
  • There are several synonymous and obsolete terms for FL such as CB/CC lymphoma (centroblastic and centrocytic lymphoma), nodular lymphoma, Brill-Symmers Disease, and the subtype designation, follicular large-cell lymphoma. (wikipedia.org)
Proliferation1
  • It decreased the STAT3 expression in B cell lymphoma cell lines (A20, SU-DHL-2 and OCI-Ly3), resulting in reduced proliferation of lymphoma cells featured with lower S-phase and higher apoptosis. (bvsalud.org)
Cell17
  • DNA-microarray analysis of Burkitt's lymphoma and diffuse large B-cell lymphoma (DLBCL) showing differences in gene expression patterns. (newworldencyclopedia.org)
  • In the US and Europe, this disease is the second most common form of non-Hodgkin's lymphomas, exceeded only by diffuse large B-cell lymphoma. (wikipedia.org)
  • In situ follicular lymphoma is an accumulation of monoclonal B cells (i.e. cells descendent from a single ancestral cell) in the germinal centers of lymphoid tissue. (wikipedia.org)
  • This translocation juxtaposes the B-cell lymphoma 2 (BCL2) gene on chromosome 18 at position q21.33 near to the immunoglobulin heavy chain locus (IGH@) on chromosome 14 at position q32. (wikipedia.org)
  • Lymphoma may be slow growing or aggressive, depending on the cell type. (ecureme.com)
  • METHODS: Here, we studied the combination of CD19-specific CAR T-cell therapy with pharmacological blockade of MCT-1 against B-cell lymphoma. (bvsalud.org)
  • Treatment with Chimeric Antigen Receptor-T cell (CAR-T) therapy is revolutionizing the management of patients with relapsed/refractory aggressive B-cell lymphoma by providing an effective alternative to the standard of care. (bvsalud.org)
  • Histiocytic/dendritic cell sarcoma arising from follicular lymphoma involving the bone: A case report and review of literature. (najms.com)
  • Baer MR, Krantz SB, Cousar JB, Glick AD, Collins RD. Malignant histiocytoses developing in patients with b-cell lymphomas. (najms.com)
  • 38= Cutaneous T-cell lymphoma, NOS (C44. (cancercentrum.se)
  • The patient suffered 7 years previously from cutaneous T cell lymphoma (mycosis fungoides). (tau.ac.il)
  • T-cell/histiocyte-rich large B-cell lymphoma - a distinct clinicopathologic entity or a variant of diffuse large B cell lymphoma? (llu.edu)
  • The diagnosis and differential diagnosis of 'small' B cell lymphomas. (llu.edu)
  • Diffuse large cell lymphomas and their mimics. (llu.edu)
  • B-cell lymphomas. (llu.edu)
  • Monoclonal gammopathies which do not meet the criteria of plasma cell myeloma, plasmocytoma or B-Cell lymphoma with plasmacytic differentiation. (muni.cz)
  • mature T/NK-cell lymphomas (C84. (who.int)
Kaposi1
PCNSL2
  • The DLBCL type of primary central nervous system lymphoma (PCNSL) is composed of immunoblasts or centroblasts that have a predilection for blood vessels and thus demonstrate a typical angiocentric growth pattern. (medscape.com)
  • Primary central nervous system lymphoma (PCNSL) is defined as lymphoma limited to the cranial-spinal axis without evidence of systemic disease and its incidence has risen threefold during the last fifteen years among apparantly healthy population. (e-crt.org)
Lymphoblastic1
  • This phase III trial studies how well blinatumomab works in combination with chemotherapy in treating patients with newly diagnosed, standard risk B-lymphoblastic leukemia or B-lymphoblastic lymphoma with or without Down syndrome. (policylab.us)
Classification3
Clinical Trials1
  • A listing of 13 Lymphoma clinical trials in Vermont actively recruiting volunteers for paid trials and research studies in various therapeutic areas. (policylab.us)
Hodgkin's2
  • FL accounts for 10-20% of non-Hodgkin's lymphomas with ~15,000 new cases of it being newly diagnosed each year in the US and Europe. (wikipedia.org)
  • Lymphoma is divided into two major types, Hodgkin's disease and non-Hodgkin's Lymphoma . (ecureme.com)
Disease1
  • For intermediate/high-grade Lymphoma , radiation treatment for local areas of the disease is sometimes given. (ecureme.com)