• TI-1 antigen, which has an activity that can directly activate B cells and TI-2 antigen, which has highly repetitive structure and causes simultaneous cross-linking of specific B cell receptors (BCR) on B lymphocyte. (wikipedia.org)
  • TI-1 antigens activate B-cells via Toll like receptors, which are expressed in humans on the surface of B lymphocytes after BCR stimulation. (wikipedia.org)
  • The activation of B lymphocytes is caused by cross-linking of a critical number of B cell receptors, which leads to accumulation of BCRs and cross activation of these receptors. (wikipedia.org)
  • Cluster of differentiation 8 (CD8), a type I transmembrane glycoprotein of the immunoglobulin family of receptors, plays an integral role in signal transduction, and T cell differentiation and activation. (thermofisher.com)
  • Ly6C high MC presented downregulated co-stimulatory receptors (CD2, GITR, and TIM1) which direct immune cell proliferation, and upregulated co-stimulatory ligands (LIGHT and SEMA4A) which trigger antigen priming and differentiation. (frontiersin.org)
  • CTLs can recognize malignant cells by interacting tumor antigens with the T cell receptors (TCR), and release cytotoxins as well as cytokines to kill malignant cells. (psu.edu)
  • discuss the role of integrins in T cell- mediated immunity, with a focus on how these receptors participate in lymphocyte recirculation and T cell activation, how antigen stimulation regulates integrin activity, and how integrins define functionally unique subsets of T cells and APCs. (scielo.br)
  • Molecules on the surface of lymphocytes called homing receptors interact specifically with HEV and play a central role in the migration. (wdv.com)
  • [4] BAFF is the natural ligand of three unusual tumor necrosis factor receptors named BAFF-R (BR3), TACI (transmembrane activator and calcium modulator and cyclophilin ligand interactor), and BCMA (B-cell maturation antigen), all of which have differing binding affinities for it. (wikidoc.org)
  • These receptors are expressed mainly on mature B lymphocytes and their expression varies in dependence of B cell maturation (TACI is also found on a subset of T-cells and BCMA on plasma cells ). (wikidoc.org)
  • CD3+ CD56+ T lymphocytes comprise a unique subset of cytotoxic T lymphocytes that mediates non-major histocompatibility complex (MHC)-restricted cytotoxicity. (bdbiosciences.com)
  • Ligation of MHC-I/peptide complexes presented by antigen-presenting cells (APCs), triggers the recruitment of lymphocyte-specific protein tyrosine kinase (Lck), which leads to lymphokine production, motility and cytotoxic T lymphocyte (CTL) activation. (thermofisher.com)
  • Adoptive cell transfer (ACT) of antigen-specific CD8 + cytotoxic T lymphocytes (CTLs) is a promising treatment for a variety of malignancies 1 . (psu.edu)
  • Intracellular antigens (eg, viruses) can be processed and presented to CD8 cytotoxic T cells by any nucleated cell because all nucleated cells express class I MHC molecules. (msdmanuals.com)
  • Kinetics and t lymphocyte dependence of the primary and secondary in vitro immune responses to the hapten 4-hydroxy-3-iodo-5-nitrophenylacetic acid presented on the carrier polymerised bacterial flagellin. (jax.org)
  • Although plasmacytoid dendritic cells (pDCs) express major histocompatibility complex class II (MHCII) molecules, and can capture, process, and present antigens (Ags), direct demonstrations that they function as professional Ag-presenting cells (APCs) in vivo during ongoing immune responses remain lacking. (unige.ch)
  • The function of the adaptive immune system is to recognize, remember and destroy invading pathogens through their antigens, and relieve pathogen-associated toxicities. (frontiersin.org)
  • Lymph nodes, in conjunction with the spleen, tonsils, adenoids, and Peyer patches, are highly organized centers of immune cells that filter antigen from the extracellular fluid. (medscape.com)
  • The immune system must distinguish not only between self and non-self, but also between innocuous and pathological foreign antigens to prevent unnecessary or self-destructive immune responses. (nature.com)
  • Van Parijs, A. & Abbas, A. K. Homeostasis and self-tolerance in the immune system: turning lymphocytes off. (nature.com)
  • Finally, we established 3 groups of transcriptional models to describe Ly6C high to Ly6C low MC subset differentiation, immune checkpoint regulation, Ly6C high MC to MΦ subset differentiation and Ly6C low MC to lymphocyte functional adaptation. (frontiersin.org)
  • The adaptive immune response, primarily comprised of T and B lymphocytes, has important implications in the fracture healing process as well [ 3 , 4 ]. (hindawi.com)
  • Dysfunction in a myriad of overlapping signalling pathways can promote endothelial cell (EC) proliferation and differentiation, smooth muscle cell (SMC) proliferation, migration and vasoconstriction, pericyte proliferation, migration and differentiation, endothelial-to-mesenchymal transition, immune cell infiltration and extracellular matrix (ECM) remodelling in the pulmonary artery. (ersjournals.com)
  • Antigens are foreign molecules that initiate an immune response, they have inherent immunogenicity (Tortora & Grabowski, 1996). (referat.ru)
  • Lymphokines are cytokines, regulators of the immune reactions which are produced by lymphocytes. (referat.ru)
  • A key mechanism of immune evasion deployed by tumour cells is to reduce neoantigen presentation through down-regulation of the antigen presentation machinery. (portlandpress.com)
  • Although T lymphocyte immunodeficiency is typically associated with P. jiroveci infection, the integrity of B lymphocyte function is also crucial to the immune response against this infection. (ijpsonline.com)
  • Sedimentation velocity and buoyant density characterization of virgin antibody-forming cell progenitors in the adoptive immune response of unprimed CBA mice to 4-hydroxy-3-iodo-5-nitrophenylacetic acid-polymerized bacterial flagellin antigen. (silverchair.com)
  • Here, we present methods for the generation of T lymphocytes from iPS cells in vitro, and in vivo programming of antigen-specific CTLs from iPS cells for promoting cancer immune surveillance. (psu.edu)
  • Молекулярні компоненти імунної системи The immune system consists of cellular components and molecular components that work together to destroy antigens (Ags). (msdmanuals.com)
  • Although some antigens (Ags) can stimulate the immune response directly, T cell-dependent acquired immune responses typically require antigen-presenting cells (APCs) to present antigen-derived peptides within major histocompatibility complex (MHC) molecules. (msdmanuals.com)
  • Antigens are the molecules that are recognized and stimulate the cells of immune system. (medscape.com)
  • The body's immune system can react adaptively against the antigen via 2 pathways: cellular or humoral. (medscape.com)
  • Epitopes are a component of the antigen that are recognized by the immune system and determine whether the cellular or the humoral arm of the immune system shall be activated against that particular antigen. (medscape.com)
  • Two days demonstrated by the present case, where the later, due to lack of clinical improvement, patient is infected with HIV, the fungus can an aliquot of the admission CSF was tested cause an infection regardless of the immune and found to have a cryptococcal antigen status of the patient. (who.int)
  • Human peripheral blood lymphocytes were stained with CD19 (clone SJ25C1) Brilliant Violet 650™ (filled histogram) or mouse IgG1, κ Brilliant Violet 650™ isotype control (open histogram). (biolegend.com)
  • CD19 is involved in B cell development, activation, and differentiation. (biolegend.com)
  • Obese adipocytes overexpress MHC class II molecules and costimulators to act as antigen-presenting cells (APCs) and promote the activation of CD4 + T cells. (frontiersin.org)
  • Several cells are known to initiate the process of plasma cell differentiation and are known collectively as antigen presenting cells (APCs) (Waller & Renwick, 1994). (referat.ru)
  • Efficient recognition of foreign pathogens by T cells requires adhesive interactions between T cells and other cell types, such as endothelial cells and antigen-presenting cells (APCs), and with components of the extracellular matrix. (scielo.br)
  • Extracellular antigens (eg, from many bacteria) must be processed into peptides and complexed with surface class II MHC molecules on professional APCs (which specialize in presenting antigens to T cells) to be recognized by CD4 helper T (Th) cells. (msdmanuals.com)
  • Dendritic cells in the skin act as sentinel APCs, taking up antigen, then traveling to local lymph nodes where they can activate T cells. (msdmanuals.com)
  • But when the concentration of TI-1 is lower, it can activate only B lymphocytes with specific binding of TI-1 on their BCR, and leads to production of monoclonal antibodies. (wikipedia.org)
  • Immunophenotyping relies on detecting specific antigenic determinants on the surface of WBCs by antigen-specific monoclonal antibodies that have been labeled with a fluorescent dye or fluorochrome, such as phycoerythrin (PE) or fluorescein isothiocyanate (FITC). (cdc.gov)
  • 1983) showed that the antigens defined by monoclonal antibodies A3D8 and A1G3 are determined by genes on 11p. (wdv.com)
  • Thymocytes were fractionated using a range of monoclonal antibodies specific for a range of lymphocyte surface antigens using complement mediated cytotoxicity (CMC) and fluorescence activated cell sorting (FACS). (gla.ac.uk)
  • The adipocyte was reported as an antigen-presenting cell (APC) which expresses CD1d and MHC class I and II molecules. (frontiersin.org)
  • To establish whether these cells were differentiated into iDCs, we analysed the expression of cell surface molecules on these cells and the capacity to capture antigens using flow cytometry. (eur.nl)
  • These experiments show that the thymocytes which can form junctions lack expression of Lyt-2 and la antigens, but express Lyt-1 molecules. (gla.ac.uk)
  • Follicular dendritic cells are a distinct lineage, do not express class II MHC molecules, and therefore do not present antigen to Th cells. (msdmanuals.com)
  • Immunoglobulins (Igs), the term is sometimes used interchangeably with "antibodies," are glycoprotein molecules produced by B lymphocytes and plasma cells in response to an immunogen or after recognition of specific epitopes on the antigen. (medscape.com)
  • Variable region constitutes the antibody binding region of the molecule to the different antigens as it consists of about 110 amino acids that vary widely among the different antibody molecules. (medscape.com)
  • CBL-1, a murine monoclonal antibody, recognises an antigen on activated T cells, B cells, and natural killer cells. (nih.gov)
  • T independent antigen elicits antibody production by B lymphocytes without T lymphocyte involvement. (wikipedia.org)
  • Human peripheral blood mononuclear cell (PBMC) lymphocytes were stained with Mouse Anti-Human CD3e PE-conjugated Monoclonal Antibody (Catalog # FAB100P ) and either (A) Mouse Anti-Human CD8a Alexa Fluor® 647-conjugated Monoclonal Antibody (Catalog # FAB1509R) or (B) Mouse IgG 2B Alexa Fluor 647 Isotype Control (Catalog # IC0041R ). (rndsystems.com)
  • METHODS: Single and double immunoenzymatic staining procedures, immunoperoxidase, and immunoalkaline phosphatase were used with Ki-67, a monoclonal antibody that recognises a nuclear antigen present in proliferating cells, with markers expressed in B and T lymphocytes and monocytes. (bmj.com)
  • HUMORAL IMMUNITYHumoral or antibody-mediated immunity is associated with B-lymphocyte cells. (referat.ru)
  • The role of complement & antibody-antigen complexesAntibodies have two distinct functions: to recognise and combine with an antigen, and to activate a defence mechanism for example by activating the complement sequence (Dale et. (referat.ru)
  • 1994). This sequence involves more than thirty proteins (Mollnes & Harboe, 1996) and has the function of the destruction and removal of invading micro-organisms and subcellular debris and to promote clearance of antigen-antibody complexes (Dale et. (referat.ru)
  • The interaction of antibody with specific antigen results in the formation of the antibody-antigen complex. (referat.ru)
  • A monoclonal antibody called rituximab can bind to the B lymphocyte's Clusters of Differentiation (CD) 20 antigen and eliminate B lymphocytes from the bloodstream. (ijpsonline.com)
  • A receptor for antibody on B lymphocytes. (wikidata.org)
  • Relationship between antigen and antibody-induced suppression of immunity. (wikidata.org)
  • The mouse monoclonal antibody Hermes-3 recognizes the 85-95 kD human lymphocyte homing receptor. (wdv.com)
  • 1983) used a murine monoclonal antibody (A3D8) to identify an erythrocyte antigen inhibited by the In(Lu) gene. (wdv.com)
  • Belimumab (Benlysta) is a monoclonal antibody developed by Human Genome Sciences and GlaxoSmithKline , with significant discovery input by Cambridge Antibody Technology , which specifically recognizes and inhibits the biological activity of B-Lymphocyte stimulator (BLyS) and is in clinical trials for treatment of Systemic lupus erythematosus and other autoimmune diseases. (wikidoc.org)
  • Identification with a monoclonal antibody of a predominantly B lymphocyte-specific determinant of the human leukocyte common antigen. (wikidata.org)
  • ALCL was recognized in 1985, when tumor cells consistently demonstrated labeling by the monoclonal antibody Ki-1, a marker later shown to recognize the CD30 antigen. (medscape.com)
  • For most protein antigens, the production of antibodies by B lymphocytes is dependent on stimulation of helper T cells. (wikipedia.org)
  • The non-protein microbial antigens cannot stimulate classical T cell response by themselves, but they are able to elicit the production of antibodies, so that is why we call them T cell or thymus independent antigens. (wikipedia.org)
  • In higher concentrations, TI-1 antigens bind to BCR and TLR of various clones of B lymphocytes, which leads to production of multiclonal antibodies. (wikipedia.org)
  • It results in proliferation and differentiation of B lymphocytes and production of antibodies. (wikipedia.org)
  • That may explain why children up to 5 years are not capable of producing effective antibodies against polysaccharide antigens, as the majority of their B cell population is immature. (wikipedia.org)
  • cells are activated by interaction with antigens and obtain T indicated that the cell lines representing a defined cell help, they mature into terminally differentiated plasma stage generally presented a high similarity in over- cells secreting large amounts of antibodies [10 -12]. (lu.se)
  • Antibodies are immunoglobulins, modified blood proteins with a specific action against antigens. (referat.ru)
  • The cellular response is mainly a lymphocyte-mediated reaction, whereas the humoral response includes production of antibodies against the antigen by the plasma cells. (medscape.com)
  • The antibodies then specifically bind to only those particular antigens. (medscape.com)
  • Antibodies can be found on the surface of lymphocytes as an integral part of the cell membrane protein or can be freely circulating in the blood or be part of one of the body's gland secretion. (medscape.com)
  • The area of Lymphocyte Development and Differentiation has been the target for several publications in previous volumes of this scientific series. (scielo.br)
  • This study aims to explore molecule signaling mediating MC subset differentiation in HHcy and control mice. (frontiersin.org)
  • CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. (biolegend.com)
  • TI-1 antigens have an intrinsic B cell activating activity, that can directly cause proliferation and differentiation of B lymphocytes without T cell stimulation and independently of their BCR specificity. (wikipedia.org)
  • In addition, various adipokines secreted by adipocytes regulate the proliferation and differentiation of T cells. (frontiersin.org)
  • It has been also shown to play an important role in the proliferation and differentiation of B cells. (wikidoc.org)
  • In the skin, nAChRs regulate the activity of genes involved in the growth and division (proliferation), maturation (differentiation), and survival of cells. (medlineplus.gov)
  • CD45 is a 180-240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. (biolegend.com)
  • CD44 is an integral cell membrane glycoprotein with a postulated role in matrix adhesion lymphocyte activation and lymph node homing. (wdv.com)
  • 1989) demonstrated that the lymphocyte homing receptor is identical to the human leukocyte surface glycoprotein called CDw44, on the basis of studies at the Third International Workshop on Human Leukocyte Differentiation Antigens. (wdv.com)
  • 1989)' 'demonstrated' 'sameness' 'the human leukocyte surface glycoprotein' 'is called' 'CDw44' 'studies' 'were conducted at' 'the Third International Workshop on Human Leukocyte Differentiation Antigens. (wdv.com)
  • the lymphocyte homing receptor' 'also appears to be identical'' to the Pgp-1 glycoprotein of Omary et al. (wdv.com)
  • Objectives: As dendritic cells (DCs) present in these skin lesions play a key role in the activation of Th lymphocytes, we investigated the effects of MMF on monocyte-derived DC differentiation. (eur.nl)
  • Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1. (wikidata.org)
  • The CD56 antigen is expressed on approximately 10% to 25% of peripheral blood lymphocytes. (bdbiosciences.com)
  • It is present on essentially all resting and activated CD16+ natural killer (NK) lymphocytes and approximately 5% of CD3+ peripheral blood lymphocytes. (bdbiosciences.com)
  • The demonstration that a proportion of normal blood lymphocytes are in cell cycle raises the issue of whether immunophenotypic analysis of Ki-67 positive cells in haemopoietic malignancies with peripheral blood disease should be carried out to define more precisely the proportion of normal and neoplastic cells in cycle. (bmj.com)
  • Peripheral blood lymphocytes (PBL) were examined, to resolve the conflict in the literature as to the ability of PBL to form communicating junctions. (gla.ac.uk)
  • CD4+ T-cells and other lymphocyte subsets in persons infected with human immunodeficiency virus (HIV). (cdc.gov)
  • The guidelines describe single-platform technology (SPT), a process in which absolute counts of lymphocyte subsets are measured from a single tube by a single instrument. (cdc.gov)
  • With CD45 gating, the relative numbers of beads and lymphocyte subsets are enumerated, and their absolute numbers and percentage values are calculated. (cdc.gov)
  • Murine MC are divided into three subsets based on surface expression of lymphocyte antigen 6 complex, locus C (Ly6C) ( 3 , 4 ). (frontiersin.org)
  • Background: CD20 is a differentiation-related antigen exclusively on the membrane of B lymphocytes. (bvsalud.org)
  • Anaplastic large cell lymphomas (ALCLs) are distinguished from other lymphomas by their anaplastic cytology and constant membrane expression of the CD30 antigen (an activation marker for B or T cells). (medscape.com)
  • Subsequent differentiation allows for rear- analysis of a set of mouse B lineage cell lines rep- rangements of the Ig light-chain (IgL) genes that replace the resenting defined stages of B cell development us- surrogate light-chain genes on the surface of the B cell [8]. (lu.se)
  • It is expressed by all lymphocytes mediating non-MHC restricted cytotoxicity and is present on some neural tissues and tumors. (bvsalud.org)
  • LymphokinesThe antigen on the surface of the APC triggers TH-cells to produce hormone-like lymphokines (Lessof, 1993). (referat.ru)
  • CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. (biolegend.com)
  • The implications of the immature surface antigen expression and the ability to form junctions are discussed and the position of thymocytes which can form junctions in intrathymic lymphocyte differentiation and development are explored. (gla.ac.uk)
  • the differentiation is based on the percentage of body surface area of skin detachment. (medscape.com)
  • The deepest structure within the lymph node is the medulla, consisting of cords of plasma cells and small B lymphocytes that facilitate immunoglobulin secretion into the exiting lymph. (medscape.com)
  • 1994). The nature of lymphocyte stimulation will determine which class of immunoglobulin will be produced (Waller & Renwick, 1994). (referat.ru)
  • Ly6C high MC exhibited activated neutrophil degranulation, lysosome, cytokine production/receptor interaction and myeloid cell activation pathways, and Ly6C low MC presented features of lymphocyte immunity pathways in both mice. (frontiersin.org)
  • Ly6C low MC manifested activated T-cell signaling pathways and potentially can adapt the function of lymphocytes. (frontiersin.org)
  • Their expression in tumour cells is modulated by a complex interplay of genomic, transcriptomic and post translational factors involving multiple intracellular antigen processing pathways. (portlandpress.com)
  • Next, we summarize various cytokines produced by adipocytes that regulate the survival, activation and differentiation of B cells. (frontiersin.org)
  • B cell activation and differentiation. (biolegend.com)
  • Stimulation in vitro with a Notch ligand drives T cell differentiation from iPS cells, and TCR gene transduction results in iPS cells differentiating into antigen-specific T cells in vivo, which prevents tumor growth. (psu.edu)
  • Although the use of hematopoietic stem cells (HSCs) for therapeutic purposes has been widely applied in clinic 11-13 , HSCs have reduced differentiation and proliferative capacities, and HSCs are difficult to expand in in vitro cell culture 14-16 . (psu.edu)
  • In a very interesting review, P. MARRACK & J. KAPPLER focus on naïve, activated, and memory T cells survival separately, and discuss experiments done in vitro and in mice lacking or containing normal populations of lymphocytes. (scielo.br)
  • In vitro MMF selectively induced type 2 cytokine production by primed Th lymphocytes, whereas type 1 cytokine production by and profileration of T lymphocytes were unaffected. (eur.nl)
  • therefore, this study aimed to establish non-hematopoietic stable cell lines overexpressing full-length human CD20 antigen as an in vitro model for CD20-related studies. (bvsalud.org)
  • The analysis was extended to immature lymphocytes of the thymus, and population of thymocytes was identified which was able to form junctions with murine fibroblasts, Swiss 3T3 and a BALB/c 3T3 and the hypoxanthine guanine phosphoribosyl transferase mutant (HGPRT-) subline of BHK/C13 baby hampster kidney fibroblast line TG2. (gla.ac.uk)
  • Our findings identify an endogenous receptor-mediated event that drives Tr1 differentiation and suggest that the complement system has a previously unappreciated role in T-cell-mediated immunity and tolerance. (nature.com)
  • Figure 1: CD3/CD46 stimulation induces IL-10 production in human peripheral blood CD4 + T lymphocytes. (nature.com)
  • CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. (biolegend.com)
  • Antigens, CD20" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ucdenver.edu)
  • This graph shows the total number of publications written about "Antigens, CD20" by people in this website by year, and whether "Antigens, CD20" was a major or minor topic of these publications. (ucdenver.edu)
  • Below are the most recent publications written about "Antigens, CD20" by people in Profiles. (ucdenver.edu)
  • Immunophenotyping analysis of stable clones demonstrated expression of CD20 antigen. (bvsalud.org)
  • Conclusion: This study is the first report on using second-generation lentiviral vectors for the establishment of a non-hematopoietic cell-based system, which stably expresses full-length human CD20 antigen. (bvsalud.org)
  • Results of stable CHO cell lines with different levels of CD20 antigen are well suited to be used for CD20-based investigations, including binding and functional assays. (bvsalud.org)
  • Other, less common etiologies responsible for adenopathy include nodal accumulation of inflammatory cells in response to an infection in the node ( lymphadenitis ), neoplastic lymphocytes or macrophages (lymphoma), or metabolite-laden macrophages in storage diseases ( Gaucher disease ). (medscape.com)
  • Ly6C high MC expressed higher levels of macrophage (MΦ) markers, whereas, Ly6C low MC highly expressed lymphocyte markers in both mice. (frontiersin.org)
  • TI-2 antigens can activate only mature B lymphocytes. (wikipedia.org)
  • Adipocytes can directly activate CD4 + T cells through antigen:MHCII complex in a contact-dependent manner. (frontiersin.org)
  • For this purpose we measured cytokine production by these LPS-stimulated cells (MMF-DCs) using enzyme-linked immunosorbent assays as well as their ability to activate naive Th lymphocytes. (eur.nl)
  • However bacterial polysaccharides and lipopolysaccharides, and some polymeric proteins, can stimulate B lymphocytes without involvement of helper T cells. (wikipedia.org)
  • MHC-I and MHC-II proteins are key components of the antigen presentation machinery responsible for neoantigen presentation to CD8 + and CD4 + T lymphocytes, respectively. (portlandpress.com)
  • the gene expression profile during B lymphoid differentiation. (lu.se)
  • For example, Omenn syndrome, a typical case of impaired T-cell differentiation with abnormal self-reactive cells, is invariably characterized by autoimmune features such as generalized scaly exudative erythroderma, enlarged lymphoid tissues, and peripheral expansion of oligoclonal T-cells, in addition to increased susceptibility for severe infections [ 3 , 4 ]. (hindawi.com)
  • A CD4 + T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. (nature.com)
  • the regulation of the proliferation, differentiation and activity of leukocytes (Dale et. (referat.ru)
  • MicroRNAs not only participate in determining DCs phenotype and then naive T lymphocyte differentiation, but also participate in the regulation of airway inflammation and airway remodeling in asthma. (cdc.gov)
  • CONCLUSIONS: The methodology described is useful for the simultaneous detection of nuclear and cytoplasmic antigens. (bmj.com)
  • Conclusions: MMF inhibited the monocyte-derived DC differentiation resulting in cells that cannot be appropriately matured to DCs. (eur.nl)