• Patients
  • This study will evaluate HIV-negative patients with unusually low levels of CD4+ T lymphocytes (a type of white blood cell) to learn more about the clinical symptoms, cause, immunology, and biology of this problem. (clinicaltrials.gov)
  • Researchers discover that lymphocyte count indicates prognosis of patients with renal cell. (bio-medicine.org)
  • Now, researchers at Fox Chase Cancer Center have discovered that the lymphocyte countwhich is routinely measured in laboratory testsis a simple and effective prognostic indicator in patients with renal cell carcinoma (RCC). (bio-medicine.org)
  • RCC patients generally have a worse prognosis if they have a suppressed immune system, which is indicated by low lymphocyte levels. (bio-medicine.org)
  • By evaluating data from more than 500 patients with the most common form of RCCcalled clear cell RCCwho had their kidneys surgically removed at Fox Chase between 1994 and 2009, Al-Saleem and his colleagues found a clear relationship between low lymphocyte counts within three months prior to surgery and a poor prognosis. (bio-medicine.org)
  • For example, about half of RCC patients are over 60 years old, and if one of these patients has other health problems and a normal lymphocyte count, a doctor may decide to monitor the patient rather than perform surgery. (bio-medicine.org)
  • Results More than half (54.9%, 485/883) of all HIV positive patients presented with CD4 count of less than 250 cells/mm3. (bmj.com)
  • Less than a quarter (18.8%, 116/883) of patients came with CD4 count of 500 cells/mm3 or more. (bmj.com)
  • Routine cryptococcal antigen screening for HIV-infected patients with low CD4+ T-lymphocyte counts: time to implement in South Africa? (scielo.org.za)
  • 7 However, despite recent progress in expanding access to ART in South Africa, 8 the median CD4+ T-cell count of patients initiating ART remains low, and a high risk of new AIDS events and mortality persists during the first months of ART. (scielo.org.za)
  • To date, preventive strategies have consisted of routine fluconazole primary prophylaxis for all patients with low CD4+ T-cell counts. (scielo.org.za)
  • This study was undertaken to determine the prevalence of cryptosporidiosis in relation to CD4+ T- lymphocyte counts of people living with HIV/AIDS (PLWHA) in Jos, Plateau State, Nigeria using formol ether concentration and saturated sodium chloride floatation techniques, modified Ziehl-Neelsen staining method, history as well as clinical records of patients. (alliedacademies.org)
  • Based on CD4+ count, the highest prevalence of 54.8% (23/42) was observed among patients with CD4+ count of ≤100. (alliedacademies.org)
  • The study, however, did find an increased number of patients with higher intraepithelial lymphocytes (IELs, a type of white bloodcell) in the oat-eating cohort. (wikipedia.org)
  • antigen
  • Regardless, the MHC antigen system that our lymphocytes recognize appears to have existed during early primate evolution, before the branching of modern taxa (Kennedy 1997, Bontrop 2006). (anthropogeny.org)
  • Effector lymphocytes function to eliminate the antigen, either by releasing antibodies (in the case of B cells), cytotoxic granules (cytotoxic T cells) or by signaling to other cells of the immune system (helper T cells). (wikipedia.org)
  • tumor
  • They also found that low counts were associated with a lower overall survival rate, even when they accounted for patient age, tumor stage and metastasis. (bio-medicine.org)
  • cells
  • They are short-lived cells resembling bursa-derived lymphocytes of birds in their production of immunoglobulin upon appropriate stimulation. (fpnotebook.com)
  • Lymphocytes are made up of NK cells (natural killer cells), T cells and B cells. (reference.com)
  • Lymphocytes should make up approximately 20 to 40 percent of the white blood cells in a sample. (reference.com)
  • Low CD4+ T-cells in the absence of known etiology has been called idiopathic CD4+ T lymphocytopenia, and a case definition was established by the CDC as a CD4 count less than 300 cells/mL on 2 consecutive samples in a patient uninfected by HIV and with no other disease or treatment that might provide a reasonable alternative explanation for CD4 lymphocytopenia. (clinicaltrials.gov)
  • 20.7% (183/883) reported with CD4 count less than 50 cell/mm3, 9.5% (84/883) with CD4 count of less than 100 cells/mm3, 24.7% (218/883) with CD4 count of less than 250 cells/mm3, 16.0% (141/883) with CD4 count of less than 350 cells/mm3, 10.3% (91/883) with CD4 count of less than 500. (bmj.com)
  • 70.9% came with CD4 count of less than 350 cells/mm3. (bmj.com)
  • Low White blood cell count is not a big deal as long as the white blood cells you have are healthy. (healthboards.com)
  • Similar to ALL, the word "lymphocytic" in CLL describes that the lymphocytes are the white blood cells this disease impacts. (face2016.ru)
  • Lymphocytes are divided into B-cells, which are responsible for antibody production (humoral immunity) and T-cells, which are responsible for cell-mediated immunity. (anthropogeny.org)
  • T-PLL has the immunophenotype of a mature (post-thymic) T-lymphocyte, and the neoplastic cells are typically positive for pan-T antigens CD2, CD3, and CD7 and negative for TdT and CD1a. (wikipedia.org)
  • Lymphocytes normally represent 20 to 40% of circulating white blood cells. (wikipedia.org)
  • The loss of S1P leads to a decrease in the total lymphocyte count in circulation, specifically CD4+ CCR7+ and CD8+ CCR7+ T cells. (wikipedia.org)
  • The three major types of lymphocyte are T cells, B cells and natural killer (NK) cells. (wikipedia.org)
  • Leukapheresis may be performed to decrease a very high white blood cell count, to obtain autologous (i.e., the patient's own) blood cells for later transplant back into the patient, or to obtain cells for research purposes. (wikipedia.org)
  • Leukocytosis is white cells (the leukocyte count) above the normal range in the blood. (wikipedia.org)
  • Lymphocytes can be further classified as T cells, B cells, and natural killer cells. (wikipedia.org)
  • Leukocytosis
  • and leukocytosis in which eosinophil count is elevated is eosinophilia. (wikipedia.org)
  • An extreme form of leukocytosis, in which the WBC count exceeds 100,000/µL, is leukostasis. (wikipedia.org)
  • For lung diseases such as pneumonia and tuberculosis, WBC count is very important for the diagnosis of the disease, as leukocytosis is usually present. (wikipedia.org)
  • thousand
  • In this study, we report a robust approach based on unique molecular identifiers that allows profiling Ag receptors for several hundred to thousand lymphocytes while preserving qualitative and quantitative information on clonal composition of the sample. (sigmaaldrich.com)
  • Medication
  • The purpose of this study is to test the safety of an investigational medication, TXA127, and its ability to increase T-lymphocyte counts, specifically CD4+ T-lymphocytes, in persons infected with human immunodeficiency virus who are taking highly active anti-retroviral therapy. (clinicaltrials.gov)
  • cell
  • CD4+ T lymphocyte (CD4) cell count testing is the standard method for determining eligibility for antiretroviral therapy (ART), but is not widely available in sub-Saharan Africa. (cdc.gov)
  • important
  • Immunologically important lymphocyte that is not thymus-dependent, is either short-lived and naive or long-lived and of memory phenotype, and resembles the bursa-derived lymphocyte of birds in that it is responsible for the production of immunoglobulins. (fpnotebook.com)
  • Levels
  • The study determined the CD4 lymphocytes count levels of HIV positive patient at first presentation at STI/HIV Clinic at Suntreso Government Hospital in Kumasi, Ghana. (bmj.com)
  • bacterial
  • Current hypotheses speculate that lymphocytes acquired their impressive recombinant abilities from a bacterial transposon or retrovirus which infected a vertebrate ancestor. (anthropogeny.org)
  • specific
  • There is no treatment for this specific symptom and the ideal management counts on dealing with the underlying cause. (face2016.ru)