- Acute myeloid leukemia Chronic myelogenous leukemia Hematopoietic stem cell Kawamoto H, Minato N (2004). (wikipedia.org)
- The expansion of acute myeloid leukemia (AML) blasts not only suppresses normal hematopoiesis, but also alters the microenvironment. (bvsalud.org)
- The high frequency of a unique neonatal preleukaemic syndrome, transient abnormal myelopoiesis (TAM), and subsequent acute myeloid leukaemia in early childhood in patients with trisomy 21 (Down syndrome) points to a specific role for trisomy 21 in transforming foetal haematopoietic cells. (ox.ac.uk)
- The word myelopoiesis has several senses in a way that parallels those of myeloid, and myelopoiesis in the narrower sense is the regulated formation specifically of myeloid leukocytes (myelocytes), allowing that sense of myelopoiesis to be contradistinguished from erythropoiesis and lymphopoiesis (even though all blood cells are normally produced in the marrow in adults). (wikipedia.org)
- Recent work using primary human foetal liver and bone marrow cells, human embryonic stem cells and iPS cells shows that prior to acquisition of GATA1 mutations, trisomy 21 itself alters human foetal haematopoietic stem cell and progenitor cell biology causing multiple abnormalities in myelopoiesis and B-lymphopoiesis. (ox.ac.uk)
- The flt3+fraction within the bone marrow Lin-Sca plus kit plus stem cell compartment efficiently reconstitutes B and T lymphopoiesis but lacks ability to long-term reconstitute myelopoiesis. (ox.ac.uk)
- in these senses the terms are usually used synonymously, as for example with chronic myeloid/myelogenous leukemia. (wikipedia.org)
- it contains short gastric vessels and associated lymphatics and sympathetic nerves. (medscape.com)
- Those cells' differentiation (that is, lymphopoiesis) is not complete until they migrate to lymphatic organs such as the spleen and thymus for programming by antigen challenge. (wikipedia.org)
- The process of lymphopoiesis (lymphocyte origination and differentiation into functional effector cells) begins in the yolk sac and continues later in life in the thymus gland, liver, spleen, and finally the bone marrow, which is the primary site of lymphopoiesis in the full-term neonate. (medscape.com)
- Previously, we showed that ATRA in combination with Lysine-specific demethylase 1 (LSD1) inhibition by tranylcypromine (TCP) can induce myeloid differentiation in AML blasts. (bvsalud.org)
- Thus, although all blood cells, even lymphocytes, are normally born in the bone marrow in adults, myeloid cells in the narrowest sense of the term can be distinguished from lymphoid cells, that is, lymphocytes, which come from common lymphoid progenitor cells that give rise to B cells and T cells. (wikipedia.org)
- Thus, among leukocytes, the term myeloid is associated with the innate immune system, in contrast to lymphoid, which is associated with the adaptive immune system. (wikipedia.org)
- Similarly, myelogenous usually refers to nonlymphocytic white blood cells, and erythroid can often be used to distinguish "erythrocyte-related" from that sense of myeloid and from lymphoid. (wikipedia.org)
- MYELOPOIESIS , in which leukocytes in the blood are derived from MYELOID STEM CELLS , and LYMPHOPOIESIS , in which leukocytes of the lymphatic system ( LYMPHOCYTES ) are generated from lymphoid stem cells. (bvsalud.org)
- There are two significant pathways to generate various types of leukocytes: MYELOPOIESIS, in which leukocytes in the blood are derived from MYELOID STEM CELLS, and LYMPHOPOIESIS, in which leukocytes of the lymphatic system (LYMPHOCYTES) are generated from lymphoid stem cells. (bvsalud.org)
- This property of specificity is what differentiates the lymphoid cell from the myeloid cell, which can react with any antigen. (medscape.com)
- Primary lymphoid tissue consists of "central" organs that serve as major sites of lymphopoiesis (Figure 10). (medscape.com)
- Once in secondary lymphoid tissues, lymphocytes may migrate from one lymphoid structure to another by vascular and lymphatic channel systems. (medscape.com)
- 6. Adult T-cell progenitors retain myeloid potential. (nih.gov)
- The word myelopoiesis has several senses in a way that parallels those of myeloid, and myelopoiesis in the narrower sense is the regulated formation specifically of myeloid leukocytes (myelocytes), allowing that sense of myelopoiesis to be contradistinguished from erythropoiesis and lymphopoiesis (even though all blood cells are normally produced in the marrow in adults). (wikipedia.org)
- The spleen is the largest ductless gland and largest single lymphatic organ in the human body. (lecturio.com)