• Centers for Diseas
  • Centers for Disease Control and Prevention: National Institute for Occupational Safety and Health. (wikipedia.org)
  • Of cases reported to the United States Centers for Disease Control and Prevention (CDC), the rate of Lyme disease infection is 7.9 cases for every 100,000 persons. (wikipedia.org)
  • Although LD is now the most common arthropod-borne illness in the U.S. (more than 150,000 cases have been reported to the Centers for Disease Control and Prevention [CDC] since 1982), its diagnosis and treatment can be challenging for clinicians due to its diverse manifestations and the limitations of currently available serological (blood) tests. (aldf.com)
  • Alzheimer's
  • They include: Alzheimer's disease Acute disseminated encephalomyelitis Viral meningitis Multiple sclerosis Bell's palsy Neuroborreliosis presenting with symptoms consistent with amyotrophic lateral sclerosis has been described. (wikipedia.org)
  • We and others have examined patients with various neurodegenerative and behavioral neurological conditions, such as Amyotrophic Lateral Sclerosis (ALS), Multiple Sclerosis (MS), Alzheimer's disease (AD) and Autistic Spectrum Disorders ([ASD], including Autism, Attention Deficit Disorder, Asperger Syndrome), and found evidence for systemic intracellular bacterial and viral infections in a majority of patients. (townsendletter.com)
  • Abstract
  • Pediatr Res, 1993 Jan,33(1Suppl):S90-4 Dept. Neurology, University Pennsylvania School of Medicine In this abstract, Guillain-Barre disease is the topic with Lyme mentioned as well. (borrelioosi.net)
  • neuropsychiatric
  • Thus the value of careful evaluation that often includes neuropsychiatric testing, SPECT and MRI brain scans, CSF analysis when appropriate, regular input from Lyme-aware neurologists, pain clinics, and occasionally specialists in psychopharmacology. (ariplex.com)
  • Neuroinflammation
  • Observed in many central nervous system diseases, neuroinflammation (NI) proceeds from peripheral immune cell infiltration into the parenchyma, from cytokine secretion and from oxidative stress. (readbyqxmd.com)
  • antibiotics
  • In the US, neuroborreliosis is typically treated with intravenous antibiotics which cross the blood-brain barrier, such as penicillins, ceftriaxone, or cefotaxime. (wikipedia.org)
  • However, about 10-15% of patients with Lyme arthritis fail the initial course of antibiotics, and some of those develop a chronic inflammatory arthritis optimally treated with local or systemic immunosuppressive agents. (springer.com)
  • 11 In contrast, if the SF-36 was used to determine Quality of Life (QOL) in post-Lyme patients, the average SF-36 physical component summary (40±9, range 29-44) and mental component summary (39±14, range 23-46) of the QOL assessment were worse than the general USA population, and they could be significantly improved by anti-Lyme antibiotics (46% versus 18%, p =0.007). (blogspot.com)
  • In addition to the general indications for all members of the tetracycline antibiotics group, doxycycline is frequently used to treat Lyme disease, chronic prostatitis, sinusitis, pelvic inflammatory disease, acne, rosacea, and rickettsial infections. (wikipedia.org)
  • bacteria
  • In Europe and Asia, the bacteria Borrelia afzelii and Borrelia garinii are also causes of the disease. (wikipedia.org)
  • Typhus Several diseases caused by Rickettsia bacteria (below) Rocky Mountain spotted fever Organism: Rickettsia rickettsii Vector: Wood tick (Dermacentor variabilis), D. andersoni Region (US): East, Southwest Vector: Amblyomma cajennense Region (Brazil): São Paulo, Rio de Janeiro, Minas Gerais. (wikipedia.org)
  • Thirteen distinct genomic classifications of Lyme disease bacteria have been identified worldwide. (wikipedia.org)
  • Doxycycline kills the symbiotic Wolbachia bacteria in the reproductive tracts of parasitic filarial nematodes, making the nematodes sterile, and thus reducing transmission of diseases such as onchocerciasis and elephantiasis. (wikipedia.org)
  • progression
  • The onset of neuroborreliosis is usually subacute with progression over weeks. (biomedcentral.com)
  • Patients with neurodegenerative diseases and behavioral disorders often have systemic bacterial, viral, and/or fungal infections that are important in disease progression and severity. (townsendletter.com)
  • 8 Such infections may also cause disease progression, and since they are usually systemic, they could affect the immune system and other organ systems, resulting in systemic signs and symptoms. (townsendletter.com)
  • Generally, LD in its later stages can also be treated effectively, but because the rate of disease progression and individual response to treatment varies from one patient to the next, some patients may have symptoms that linger for months or even years following treatment. (aldf.com)
  • findings
  • Ocular Lyme disease has also been reported, as has neuroborreliosis affecting the spinal cord, but neither of these findings are common. (wikipedia.org)
  • In the first part of this review we considered neurodegenerative and neurobehavioural diseases and the findings that these diseases commonly are associated with systemic and central nervous system bacterial and viral infections. (blogspot.com)
  • endemic
  • Lyme disease is most endemic in Northern Hemisphere temperate regions, but sporadic cases have been described in other areas of the world. (wikipedia.org)
  • antibodies
  • The invention is also directed to a method of diagnosing Lyme disease by detecting the antigens in a biological sample taken from a host using the antibodies in conventional immunoassay formats. (freepatentsonline.com)
  • antibiotic treatment
  • When interpreting immunodiagnostic test results it has to be considered that there are a lot of variability as the phenotype characteristics of borrelia, different antigenic structures, different geographical distribution, phase varies in duration of the disease, characteristics of individual immune responses, presence of other diseases as well as the applied antibiotic treatment, which all can affect the outcome. (md-medicaldata.com)
  • neurodegenerative
  • The tumor necrosis factor-like weak inducer of apoptosis (TWEAK)/Fn14 pathway has been involved in chronic human inflammatory pathologies such as neurodegenerative, autoimmune, or malignant diseases. (readbyqxmd.com)
  • Neurodegenerative diseases are chronic degenerative diseases of the central nervous system (CNS) that often cause dementia in the aging population. (townsendletter.com)
  • There appears to be a genetic link to neurodegenerative diseases, but the genetic changes that occur and the changes in gene expression that are found in these diseases are complex and not related to simple genetic mutations, deletions, or amplifications. (townsendletter.com)
  • 1 In addition to genetic changes and changes in gene expression, it is thought that nutritional deficiencies, head trauma, environmental toxins, chronic bacterial and viral infections, autoimmune immunological responses, vascular diseases, accumulation of fluid in the brain, changes in neurotransmitter concentrations, and other causes are involved in various neurodegenerative diseases. (townsendletter.com)
  • juvenile
  • It was first identified in 1975 in the town of Old Lyme, CT after an outbreak of juvenile rheumatoid arthritis. (davidson.edu)
  • Orczyk K, Swidrowska-Jaros J, Smolewska E. When a patient suspected with juvenile idiopathic arthritis turns out to be diagnosed with an infectious disease - a review of Lyme arthritis in children. (springer.com)
  • Epidemic
  • Lyme arthritis: an epidemic of oligoarticular arthritis in children and adults in three connecticut communities. (springer.com)