• Alzheimer's
  • They include: Alzheimer's disease Acute disseminated encephalomyelitis Viral meningitis Multiple sclerosis Bell's palsy Neuroborreliosis presenting with symptoms consistent with amyotrophic lateral sclerosis has been described. (wikipedia.org)
  • We and others have examined patients with various neurodegenerative and behavioral neurological conditions, such as Amyotrophic Lateral Sclerosis (ALS), Multiple Sclerosis (MS), Alzheimer's disease (AD) and Autistic Spectrum Disorders ([ASD], including Autism, Attention Deficit Disorder, Asperger Syndrome), and found evidence for systemic intracellular bacterial and viral infections in a majority of patients. (townsendletter.com)
  • Neurology
  • The American Academy of Neurology (AAN) published a practice parameter in 2001 stating that steroids are probably effective and acyclovir (with prednisone) is possibly effective for the treatment of Bell palsy. (medscape.com)
  • species
  • Prevalence of antibodies against Borrella species in patients with unclassified uveitis in regions in with Lyme disease is endemic' Clin.Diag.Labo.Immunol.2. (nii.ac.jp)
  • Neuroinflammation
  • Observed in many central nervous system diseases, neuroinflammation (NI) proceeds from peripheral immune cell infiltration into the parenchyma, from cytokine secretion and from oxidative stress. (readbyqxmd.com)
  • antibiotics
  • In the US, neuroborreliosis is typically treated with intravenous antibiotics which cross the blood-brain barrier, such as penicillins, ceftriaxone, or cefotaxime. (wikipedia.org)
  • 11 In contrast, if the SF-36 was used to determine Quality of Life (QOL) in post-Lyme patients, the average SF-36 physical component summary (40±9, range 29-44) and mental component summary (39±14, range 23-46) of the QOL assessment were worse than the general USA population, and they could be significantly improved by anti-Lyme antibiotics (46% versus 18%, p =0.007). (blogspot.com)
  • In addition to the general indications for all members of the tetracycline antibiotics group, doxycycline is frequently used to treat Lyme disease, chronic prostatitis, sinusitis, pelvic inflammatory disease, acne, rosacea, and rickettsial infections. (wikipedia.org)
  • bacteria
  • Typhus Several diseases caused by Rickettsia bacteria (below) Rocky Mountain spotted fever Organism: Rickettsia rickettsii Vector: Wood tick (Dermacentor variabilis), D. andersoni Region (US): East, Southwest Vector: Amblyomma cajennense Region (Brazil): São Paulo, Rio de Janeiro, Minas Gerais. (wikipedia.org)
  • Thirteen distinct genomic classifications of Lyme disease bacteria have been identified worldwide. (wikipedia.org)
  • Doxycycline kills the symbiotic Wolbachia bacteria in the reproductive tracts of parasitic filarial nematodes, making the nematodes sterile, and thus reducing transmission of diseases such as onchocerciasis and elephantiasis. (wikipedia.org)
  • Africa
  • With so many vectors, the underlying assumption behind this checklist is that Lyme is not rare in North America, Europe, South America, Russia, Africa or Asia. (lymebook.com)
  • Newly discovered genospecies have also been found to cause disease in humans: B. lusitaniae in Europe (especially Portugal), North Africa and Asia. (wikipedia.org)
  • The disease is rarely detected in northern Africa and Mediterranean countries ( 3 , 6 , 7 ). (cdc.gov)
  • endemic
  • Lyme disease is most endemic in Northern Hemisphere temperate regions, but sporadic cases have been described in other areas of the world. (wikipedia.org)
  • This might be due to the very low incidence in an endemic region (0.2%, CI 95% 0.0% to 1.1%) as demonstrated in 517 patients hospitalized for psychiatric diseases. (blogspot.com)
  • antibodies
  • The invention is also directed to a method of diagnosing Lyme disease by detecting the antigens in a biological sample taken from a host using the antibodies in conventional immunoassay formats. (freepatentsonline.com)
  • neurodegenerative
  • The tumor necrosis factor-like weak inducer of apoptosis (TWEAK)/Fn14 pathway has been involved in chronic human inflammatory pathologies such as neurodegenerative, autoimmune, or malignant diseases. (readbyqxmd.com)
  • Patients with neurodegenerative diseases and behavioral disorders often have systemic bacterial, viral, and/or fungal infections that are important in disease progression and severity. (townsendletter.com)
  • Neurodegenerative diseases are chronic degenerative diseases of the central nervous system (CNS) that often cause dementia in the aging population. (townsendletter.com)
  • There appears to be a genetic link to neurodegenerative diseases, but the genetic changes that occur and the changes in gene expression that are found in these diseases are complex and not related to simple genetic mutations, deletions, or amplifications. (townsendletter.com)
  • 1 In addition to genetic changes and changes in gene expression, it is thought that nutritional deficiencies, head trauma, environmental toxins, chronic bacterial and viral infections, autoimmune immunological responses, vascular diseases, accumulation of fluid in the brain, changes in neurotransmitter concentrations, and other causes are involved in various neurodegenerative diseases. (townsendletter.com)
  • In the first part of this review we considered neurodegenerative and neurobehavioural diseases and the findings that these diseases commonly are associated with systemic and central nervous system bacterial and viral infections. (blogspot.com)
  • patients
  • Not all patients with Lyme disease have all symptoms, and many of the symptoms are not specific to Lyme disease, but can occur with other diseases, as well. (wikipedia.org)
  • showed that patients with neuroborreliosis demonstrate a blood brain barrier disturbance with 62 % showing an elevated albumin ratio and 60 % revealing an increased IgG index, indicative of intrathecal IgG synthesis. (upmc.edu)
  • Generally, LD in its later stages can also be treated effectively, but because the rate of disease progression and individual response to treatment varies from one patient to the next, some patients may have symptoms that linger for months or even years following treatment. (aldf.com)
  • In working with a number of patients with Lyme/tick-borne diseases it is apparent to many clinicians these conditions can cause reduced frustration tolerance, irritability, depression , cognitive impairments and mood swings, but more significantly, in a few patients, suicidal and aggressive tendencies. (psychologytoday.com)
  • this rash occurs in 75% of patients infected with Lyme disease and tends to resolve from the inside-out, leaving a bull's eye mark on the skin (Frey 2002). (davidson.edu)
  • Use of bisphosphonates in patients with conditions or diseases affecting renal function is not recommended. (issuu.com)
  • Dr. Jemsek s Clinic sees more new patients for Lyme Disease than any other facility in the country. (lymediseaseaction.org.uk)
  • More recently he became involved in the care of patients with Lyme Disease and he is a member of the International Lyme and Associated Diseases Society (ILADS). (lymediseaseaction.org.uk)
  • amyotrophic lateral s
  • Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND) and Lou Gehrig's disease, is a specific disease which causes the death of neurons controlling voluntary muscles. (wikipedia.org)
  • ALS is a motor neuron disease, also spelled "motor neurone disease", which is a group of neurological disorders that selectively affect motor neurons, the cells that control voluntary muscles of the body, including amyotrophic lateral sclerosis (ALS), primary lateral sclerosis, progressive muscular atrophy, progressive bulbar palsy, pseudobulbar palsy, and spinal muscular atrophy. (wikipedia.org)
  • Cognitive
  • Cognitive processing speed in Lyme disease. (borrelioosi.net)
  • Can microbes and immune reactions to them actually contribute to cognitive decline, degenerative neurological disease, developmental disabilities, mental illness, personality changes and, at the most extreme, even violent and criminal behavior? (psychologytoday.com)
  • 2016
  • Lyme Disease Differential Diagnoses: Diagnostic Considerations Updated: Mar 14, 2016 CDC Two-step Laboratory Testing Process Page last reviewed: March 4, 2015. (wikipedia.org)
  • infections
  • An attractive model for neurodegeneration resulting in neurological disease involves the action of toxic products produced as a result of chronic bacterial and/or viral infections. (townsendletter.com)
  • 8 Such infections may also cause disease progression, and since they are usually systemic, they could affect the immune system and other organ systems, resulting in systemic signs and symptoms. (townsendletter.com)
  • multisystem
  • LD manifests itself as a multisystem inflammatory disease that affects the skin in its early, localized stage, and spreads to the joints, nervous system and, to a lesser extent, other organ systems in its later, disseminated stages. (aldf.com)