• enzymology
  • In enzymology, a chorismate lyase (EC 4.1.3.40) is an enzyme that catalyzes the chemical reaction chorismate ⇌ {\displaystyle \rightleftharpoons } 4-hydroxybenzoate + pyruvate Hence, this enzyme has one substrate, chorismate, and two products, 4-hydroxybenzoate and pyruvate. (wikipedia.org)
  • In enzymology, a xanthan lyase (EC 4.2.2.12) is an enzyme that catalyzes the chemical reaction of cleaving the beta-D-mannosyl-beta-D-1,4-glucuronosyl bond on the polysaccharide xanthan. (wikipedia.org)
  • In enzymology, a pectin lyase also known as pectolyase is a naturally occurring pectinase a type of enzyme that degrades pectin. (wikipedia.org)
  • In enzymology, a mandelonitrile lyase (EC 4.1.2.10, (R)-HNL, (R)-oxynitrilase, (R)-hydroxynitrile lyase) is an enzyme that catalyzes the chemical reaction mandelonitrile ⇌ {\displaystyle \rightleftharpoons } hydrogen cyanide + benzaldehyde Hence, this enzyme has one substrate, mandelonitrile, and two products, hydrogen cyanide and benzaldehyde. (wikipedia.org)
  • In enzymology, a selenocysteine lyase (EC 4.4.1.16) is an enzyme that catalyzes the chemical reaction L-selenocysteine + reduced acceptor ⇌ {\displaystyle \rightleftharpoons } selenide + L-alanine + acceptor Thus, the two substrates of this enzyme are L-selenocysteine and reduced acceptor, whereas its 3 products are selenide, L-alanine, and acceptor. (wikipedia.org)
  • In enzymology, an oligogalacturonide lyase (EC 4.2.2.6) is an enzyme that catalyzes the chemical reaction 4-(4-deoxy-beta-D-gluc-4-enuronosyl)-D-galacturonate ⇌ {\displaystyle \rightleftharpoons } 2 5-dehydro-4-deoxy-D-glucuronate Hence, this enzyme has one substrate, 4-(4-deoxy-beta-D-gluc-4-enuronosyl)-D-galacturonate, and one product, 5-dehydro-4-deoxy-D-glucuronate. (wikipedia.org)
  • In enzymology, a lactoylglutathione lyase (EC 4.4.1.5) (also known as glyoxalase I) is an enzyme that catalyzes the isomerization of hemithioacetal adducts, which are formed in a spontaneous reaction between a glutathionyl group and aldehydes such as methylglyoxal. (wikipedia.org)
  • In enzymology, a hyaluronate lyase (EC 4.2.2.1) is an enzyme that catalyzes the chemical reaction Cleaves hyaluronate chains at a beta-D-GalNAc-(1->4)-beta-D-GlcA bond, ultimately breaking the polysaccharide down to 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. (wikipedia.org)
  • PMID
  • When the backbone of pectin is methylated it is known as pectin, and can be cleaved by pectin lyase, a microbial virulence factor [ PMID: 9195887 ]. (ebi.ac.uk)
  • When the backbone of pectin is demethylated it is known as pectate, and can be cleaved by pectate lyase virulence factors, or hydrolysed by polygalacturonases [ PMID: 12324535 , PMID: 11518536 ]. (ebi.ac.uk)
  • Adenylosuccinase, EC:4.3.2.2 (adenylosuccinate lyase) [ PMID: 1574589 ], which catalyses the eighth step in the de novo biosynthesis of purines, the formation of 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide and fumarate from 1-(5-phosphoribosyl)-4-(N-succino-carboxamide). (ebi.ac.uk)
  • enzyme that catalyzes
  • In biochemistry, a lyase is an enzyme that catalyzes the breaking (an "elimination" reaction) of various chemical bonds by means other than hydrolysis (a "substitution" reaction) and oxidation, often forming a new double bond or a new ring structure. (wikipedia.org)
  • Pectin lyase is an enzyme that catalyzes the chemical reaction Eliminative cleavage of (1->4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their non-reducing ends This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. (wikipedia.org)
  • ASL (argininosuccinate lyase, also known as argininosuccinase) is an enzyme that catalyzes the reversible breakdown of argininosuccinate (ASA) producing the amino acid arginine and dicarboxylic acid fumarate. (wikipedia.org)
  • pectin lyase
  • This entry covers proteins that are closely related to the pectolytic enzyme, pectin lyase, which act as virulence factors. (ebi.ac.uk)
  • Two crystal structures of pectin lyase A from Aspergillus reveal a pH driven conformational change and striking divergence in the substrate-binding clefts of pectin and pectate lyases. (ebi.ac.uk)
  • The first report on retting of sunn hemp (Crotalaria juncea) by pectin lyase produced by Aspergillus flavus MTCC 7589 was published in 2008 but this aspect of pectin lyases needs to be extensively investigated further. (wikipedia.org)
  • Application of mass spectrometry to determine the activity and specificity of pectin lyase A". Carbohydr. (wikipedia.org)
  • Protein
  • Delta-crystallin shares around 90% sequence identity with arginosuccinate lyase, showing that it is an example of a 'hijacked' enzyme - accumulated mutations have, however, rendered the protein enzymatically inactive. (ebi.ac.uk)
  • The protein encoded by this gene belongs to the HMG-CoA lyase family. (nih.gov)
  • synthase
  • Methylisocitrate lyase is used in the methylcitrate cycle, a modified version of the Krebs cycle that metabolizes propionyl coenzyme A instead of acetyl coenzyme A. The enzyme 2-methylcitrate synthase adds propionyl coenzyme A to oxaloacetate, yielding methylcitrate instead of citrate. (wikipedia.org)
  • catalyses
  • This enzyme catalyses the following chemical reaction S-(2E,6E)-farnesyl-L-cysteine + O2 + H2O ⇌ {\displaystyle \rightleftharpoons } (2E,6E)-farnesal + L-cysteine + H2O2 Farnesylcysteine lyase is a flavoprotein (FAD). (wikipedia.org)
  • A combination of both an elimination and a Michael addition is seen in O-succinylhomoserine (thiol)-lyase (MetY or MetZ) which catalyses first the γ-elimination of O-succinylhomoserine (with succinate as a leaving group) and then the addition of sulfide to the vinyl intermediate, this reaction was first classified as a lyase (EC 4.2.99.9), but was then reclassified as a transferase (EC 2.5.1.48). (wikipedia.org)
  • proteins
  • These proteins include pectate lyase, iota-carrageenase, and glycoside hydrolases from family 28 (such as galacturonases). (ebi.ac.uk)
  • include
  • Other names in common use include alpha-hydroxyglycine amidating dealkylase, peptidyl-alpha-hydroxyglycine alpha-amidating lyase, HGAD, PGL, PAL, and peptidylamidoglycolate peptidylamide-lyase. (wikipedia.org)
  • Other names in common use include selenocysteine reductase, and selenocysteine beta-lyase. (wikipedia.org)
  • Other names in common use include oligogalacturonate lyase, unsaturated oligogalacturonate transeliminase, and OGTE. (wikipedia.org)
  • other names include methylglyoxalase, aldoketomutase, ketone-aldehyde mutase, and (R)-S-lactoylglutathione methylglyoxal-lyase (isomerizing). (wikipedia.org)
  • activity
  • Influence of multiple cysteines on human 3-hydroxy-3-methylglutaryl-CoA lyase activity and formation of inter-subunit adducts. (nih.gov)
  • known
  • Pectin lyases are the only known pectinases capable of degrading highly esterified pectins (like those found in fruits) into small molecules via β-elimination mechanism without producing methanol (which is toxic), in contrast with the combination of PG and PE, which are normally found in commercial products. (wikipedia.org)