• proteins
  • In the February issue of Nature Genetics , Ballif and his colleagues report on their discovery of two proteins on red blood cells responsible for these lesser-known blood types. (uvm.edu)
  • Only 30 proteins have previously been identified as responsible for a basic blood type," Ballif notes, "but the count now reaches 32. (uvm.edu)
  • The last new blood group proteins to be discovered were nearly a decade ago, Ballif says, "so it's pretty remarkable to have two identified this year. (uvm.edu)
  • With this machine, he analyzed proteins purified by his longtime collaborator, Lionel Arnaud at the French National Institute for Blood Transfusion in Paris, France. (uvm.edu)
  • There Arnaud and his team conducted cellular and genetic tests confirming that these proteins were responsible for the Langereis and Junior blood types. (uvm.edu)
  • With the findings from this new research, health care professionals will now be able to more rapidly and confidently screen for these novel blood group proteins, Ballif wrote in a recent news article. (uvm.edu)
  • If our own blood cells don't have these proteins, they're not familiar to our immune system," Ballif says, so the new blood doesn't "look like self" to the complex cellular defenses of the immune system. (uvm.edu)
  • The cell membrane is composed of proteins and lipids, and this structure provides properties essential for physiological cell function such as deformability and stability while traversing the circulatory system and specifically the capillary network. (wikipedia.org)
  • Having oxygen-carrying proteins inside specialized cells (as opposed to oxygen carriers being dissolved in body fluid) was an important step in the evolution of vertebrates as it allows for less viscous blood, higher concentrations of oxygen, and better diffusion of oxygen from the blood to the tissues. (wikipedia.org)
  • Plasma, which constitutes 55% of blood fluid, is mostly water (92% by volume), and contains dissipated proteins, glucose, mineral ions, hormones, carbon dioxide (plasma being the main medium for excretory product transportation), and blood cells themselves. (wikipedia.org)
  • cell
  • In our blood the dominant thing in there are cells and red blood cell are the most abundant. (lifepositivism.com)
  • This can lead to hemolytic anemia, in which the body destroys the transfused blood, leading to low red blood cell counts. (wikipedia.org)
  • As red blood cells approach the renal medulla (where there is a high concentration of urea), the urea transporter allows for rapid uptake of urea and prevents cell shrinkage in the hypertonic environment of the medulla. (wikipedia.org)
  • Red blood cells (RBCs), also called erythrocytes, are the most common type of blood cell and the vertebrate's principal means of delivering oxygen (O2) to the body tissues-via blood flow through the circulatory system. (wikipedia.org)
  • Red blood cells are also known as RBCs, red cells, red blood corpuscles, haematids, erythroid cells or erythrocytes (from Greek erythros for "red" and kytos for "hollow vessel", with -cyte translated as "cell" in modern usage). (wikipedia.org)
  • Oxygen can easily diffuse through the red blood cell's cell membrane. (wikipedia.org)
  • red blood cell width is on average about 25% larger than capillary diameter, and it has been hypothesized that this improves the oxygen transfer from red blood cells to tissues. (wikipedia.org)
  • However, there are some exceptions concerning shape in the artiodactyl order (even-toed ungulates including cattle, deer, and their relatives), which displays a wide variety of bizarre red blood cell morphologies: small and highly ovaloid cells in llamas and camels (family Camelidae), tiny spherical cells in mouse deer (family Tragulidae), and cells which assume fusiform, lanceolate, crescentic, and irregularly polygonal and other angular forms in red deer and wapiti (family Cervidae). (wikipedia.org)
  • Estimation
  • Korop O.A. Integral estimation of efficiency of development of system of the specialized medicare in the conditions of introduction and functioning of general practice - domestic medicine. (ozizdrav.ru)
  • carbon dioxide
  • most waste carbon dioxide, however, is transported back to the pulmonary capillaries of the lungs as bicarbonate (HCO3−) dissolved in the blood plasma. (wikipedia.org)
  • In animals with lungs, arterial blood carries oxygen from inhaled air to the tissues of the body, and venous blood carries carbon dioxide, a waste product of metabolism produced by cells, from the tissues to the lungs to be exhaled. (wikipedia.org)
  • transfusions
  • Although minor erythrocyte antigens are not considered clinically significant in sporadic transfusions, they may be relevant for multi-transfusion patients. (readbyqxmd.com)
  • This will leave them better prepared to have blood ready when blood transfusions or other tissue donations are required," he notes. (uvm.edu)
  • arterial blood
  • Pulse oximetry takes advantage of the hemoglobin color change to directly measure the arterial blood oxygen saturation using colorimetric techniques. (wikipedia.org)
  • cells of mammals
  • The red blood cells of mammals are typically shaped as biconcave disks: flattened and depressed in the center, with a dumbbell-shaped cross section, and a torus-shaped rim on the edge of the disk. (wikipedia.org)
  • donors
  • RBC genotyping of 419 blood donors was performed using a Lifecodes RBC/RBC-R typing kit (Immucor, Norcross, GA). (readbyqxmd.com)
  • And Junior-negative blood donors are extremely rare too. (uvm.edu)
  • erythrocyte
  • The aim of this study was to evaluate the utility of blood group genotyping and compare the molecular typing of erythrocyte antigens with the established serological methods. (readbyqxmd.com)
  • Human blood fractioned by centrifugation: Plasma (upper, yellow layer), buffy coat (middle, thin white layer) and erythrocyte layer (bottom, red layer) can be seen. (wikipedia.org)
  • RBCs
  • The blood cells are mainly red blood cells (also called RBCs or erythrocytes), white blood cells (also called WBCs or leukocytes) and platelets (also called thrombocytes). (wikipedia.org)
  • If all human hemoglobin were free in the plasma rather than being contained in RBCs, the circulatory fluid would be too viscous for the cardiovascular system to function effectively. (wikipedia.org)
  • vessels
  • This distinctive biconcave shape optimises the flow properties of blood in the large vessels, such as maximization of laminar flow and minimization of platelet scatter, which suppresses their atherogenic activity in those large vessels. (wikipedia.org)
  • Blood is circulated around the body through blood vessels by the pumping action of the heart. (wikipedia.org)
  • Compatibility
  • Compatibility of ABH antigens has important impacts on the prognoses of transplants of kidneys, livers and hearts, but less so on marrow, bone or cornea transplantation prognoses. (wikipedia.org)
  • Many people never took into considerations the risky implications of getting married and giving birth to children without first testing to ascertain the compatibility of their blood types and genotype. (lifepositivism.com)
  • genetic
  • Although the antigens for the Junior and Langereis (or Lan) blood types were identified decades ago in pregnant women having difficulties carrying babies with incompatible blood types, the genetic basis of these antigens has been unknown until now. (uvm.edu)
  • presence
  • Diagnosis is by the presence of erythroblasts, high reticulocyte count and a positive direct antiglobulin test (DAT) in cord blood and a positive indirect antiglobulin test (IAT) in maternal blood. (ndtv.com)
  • Cont Nou use Stochastic Approaches for Systems of small presence blastomeres and vital, main method cancer. (ecombinatii.ro)
  • In terms of anatomy and histology, blood is considered a specialized form of connective tissue, given its origin in the bones and the presence of potential molecular fibers in the form of fibrinogen. (wikipedia.org)