Cisplatin and etoposideSCLCCancersCarboplatin and etoposideIncidence of lung cancerPaclitaxelCyclophosphamideConcurrentIfosfamide and etoposideNSCLCLymph nodesEfficacyAtezolizumabTumorsRadiationPlatinum-Based ChemotherapyDevelop lung cancer50mgCombinationAnlotinibExposureDoxorubicinEtiologyIntravenouslyMortalityMetastasisSmallIncreasesMelanomaDecreasesType of lung cancerDeaths from lung cancerTreatment of lung cancerAssociated with lung cancerSignificantlyProstate cancerOralDrugsExtensive-stageBiopsySmokers
Cisplatin and etoposide3
- All those enrolled were treated with 3 initial cycles of cisplatin and etoposide (PE) chemotherapy. (oncolink.org)
- He was started on a combination of cisplatin and etoposide in a neoadjuvant fashion. (ispub.com)
- He was started on cisplatin and etoposide and had a partial response to chemotherapy. (ispub.com)
SCLC25
- 63.2% had non-small-cell lung cancer (NSCLC), and 36.8% had small-cell lung cancer (SCLC). (lungevity.org)
- Treatment for extensive stage small cell lung cancer (SCLC) usually involves combination treatment. (healthline.com)
- Anlotinib plus chemotherapy as first-line treatment for extensive-stage small- cell lung cancer (ES-SCLC) achieves good efficacy , but there is still room for improvement. (bvsalud.org)
- This clinical study examined the effectiveness of anlotinib plus etoposide for maintenance therapy in ES-SCLC. (bvsalud.org)
- Maintenance anlotinib plus etoposide achieves promising PFS and OS in clinical ES-SCLC. (bvsalud.org)
- Thirty-three chemotherapy-naive patients with limited-stage small cell lung cancer (LS-SCLC) were treated with etoposide 100mg/m(2) on days 1-3 and cisplatin 80mg/m(2) on day 1. (ogologos-giassas.com)
- Histologically or pathologically confirmed extensive stage small cell lung cancer (ES-SCLC). (swog.org)
- Here, we describe the development of ABBV-011, a novel SEZ6-targeted, calicheamicin-based ADC for the treatment of small cell lung cancer (SCLC). (aacrjournals.org)
- 'Unprecedented' 3-Year Sustained Survival in SCLC With New Combo The combination of durvalumab plus etoposide and cisplatin/carboplatin should now become the standard of care for the first-line treatment of extensive-stage small cell lung cancer (ES-SCLC). (medscape.com)
- There are two broad classes of lung cancers - non-small cell lung cancer (NSCLC), which represents the vast majority of lung tumors, and small cell lung cancer (SCLC), which accounts for less than 20 percent of lung cancers. (aacr.org)
- Does Small-Cell Lung Cancer (SCLC) Respond to Chemotherapy? (healthline.com)
- Small-cell lung cancer (SCLC) tends to be more aggressive and more difficult to treat than the other main type of lung cancer, non-small cell lung cancer (NSCLC) . (healthline.com)
- Although I was not involved in the development of the original NCCN Guidelines for Small Cell Lung Cancer (SCLC) 20 years ago, I have now been a member of the panel for 16 years and have served as panel chair since 2006. (jnccn.org)
- The treatment combination of benmelstobart and anlotinib with Vepesid (etoposide) plus Paraplatin (carboplatin) as first-line treatment significantly improved survival outcomes for patients with extensive-stage small cell lung cancer (ES-SCLC), according to data from a phase 3 trial. (curetoday.com)
- Small cell lung cancer (SCLC) is characterized by rapid growth and early dissemination. (medscape.com)
- Several platinum-based and non-platinum-based chemotherapy regimens have been used in the treatment of small cell lung cancer (SCLC) with varying results. (medscape.com)
- Small cell lung cancer (SCLC), previously known as oat cell carcinoma, is considered distinct from other lung cancers, which are called non-small cell lung cancers (NSCLCs) because of their clinical and biologic characteristics. (medscape.com)
- Also, see the Clinical Presentations of Lung Cancer: Slideshow and Lung Cancer Staging -- Radiologic Options slideshows for additional information on SCLC staging and treatment. (medscape.com)
- SCLC is an aggressive subtype of lung cancer. (medscape.com)
- Small cell lung carcinoma (SCLC) arises in peribronchial locations and infiltrates the bronchial submucosa. (medscape.com)
- The predominant cause of small cell lung cancer (SCLC) (and non-SCLC) is tobacco smoking. (medscape.com)
- Of all histologic types of lung cancer, SCLC and squamous cell carcinoma have the strongest correlation to tobacco. (medscape.com)
- All types of lung cancer occur with increased frequency in uranium miners, but SCLC is the most common. (medscape.com)
- The incidence of small cell lung cancer (SCLC) has declined over the last few years. (medscape.com)
- 1. Non-small cell lung cancer (NSCLC) or combined SCLC and NSCLC. (who.int)
Cancers16
- Celoside 100 Injection is used to treat different cancers of lung, and testicles. (pmaoverseas.com)
- Daxotel 120mg Injection is an anti-cancer medication used for the treatment of breast cancer, non-small cell lung cancer, prostate cancer and cancers of head and neck. (pmaoverseas.com)
- Blockade of pathways involving PD-1 and its ligand is a promising treatment for cancers (melanoma, nonsmall cell lung cancer, metastatic renal cell carcinoma, head and neck carcinomas, Hodgkin lymphoma, and urothelial carcinoma) ( 4 ), although the role of PD1/programmed death ligand 1 in immune suppression and the mechanism of action of antibodies remain to be better defined. (cdc.gov)
- In 2016, there will be an estimated 224,390 new cases of lung cancer accounting for about 14 percent of all cancers: an estimated 117,920 cases will be diagnosed in men and 106,470 in women. (healthywomen.org)
- Scientists have shown that some cancers (e.g., breast cancer) involve genes that are passed down from parents to their children, and the link between such genetic mutations and lung cancer is also becoming more probable. (healthywomen.org)
- While genetic mutations may play a role, we know that smoking is the number one cause of lung cancer-about 80 percent of lung cancers are thought to be the result of smoking, according to the American Lung Association. (healthywomen.org)
- Lung cancer - one of the most commonly diagnosed cancers in the United States - is an area of intense research and clinical development. (aacr.org)
- As detailed extensively in a recent review article published in Cancer Epidemiology, Biomarkers & Prevention , lung cancers have a host of different risk factors. (aacr.org)
- There are, however, non-tobacco risk factors for developing lung cancers. (aacr.org)
- lung cancer already has a lower survivability rate after five years than other prominent cancers such as prostate ( 98% ) and breast ( 90% ), at only 19% . (biospace.com)
- Among the kinds of lung cancer, non-small cell lung cancer (NSCLC) accounts for about 85% of the total number of lung cancers. (biomedcentral.com)
- He has authored or co-authored papers and book chapters regarding the management of lung and head and neck cancers. (mdanderson.org)
- Dr. Blumenschein's area of focus is in new drug development, adoptive T-cell therapy and multimodality therapy for the treatment of lung and head and neck cancers. (mdanderson.org)
- He is leading the Adoptive T-cell Program with the goal of developing this class of therapeutics for the treatment of Lung and Head and Neck Cancers. (mdanderson.org)
- it now comprises only about 15% of all lung cancers. (medscape.com)
- Chronic inflammation increases the risk of many cancers, including lung cancer. (msdmanuals.com)
Carboplatin and etoposide2
- Adebrelimab or placebo plus carboplatin and etoposide as first-line treatment for extensive-stage small-cell lung cancer (CAPSTONE-1): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial. (nih.gov)
- Phase I Study of Entinostat, Atezolizumab, Carboplatin, and Etoposide in Previously Untreated Extensive-Stage Small Cell Lung Cancer, ETCTN 10399. (cdc.gov)
Incidence of lung cancer5
- The incidence of lung cancer in women has climbed at an alarming rate. (healthywomen.org)
- In the United States, the incidence of lung cancer among never smokers (LCANS) is increasing, and roughly 10-20 percent of lung cancer diagnoses occur in those who have never smoked. (aacr.org)
- The increasing incidence of lung cancer in my country is the main cause of the death of malignant tumors [ 1 ]. (biomedcentral.com)
- The incidence of lung cancer is increased further in these individuals if they also smoke tobacco. (medscape.com)
- Although the incidence of lung cancer has been falling in the US, it is increasing at a staggering pace in developing countries due to the rising prevalence of tobacco use. (medscape.com)
Paclitaxel2
- Leading 100% Export Oriented Unit of etoposide (100mg) celon laboratories ltd celoside 100mg injection, packaging: 1 vial, daxotel 120 mg injection, erlocip 150 erlotinib tablets ip 150 mg, gemtero 1g injection, pemetrexed pemetero 500 mg injection, hetero, 1 vial and paclitaxel nab paclitero 100mg, vial, prescription from Nagpur. (pmaoverseas.com)
- Cisplatin is mainly used in treatment of non-small cell lung carcinoma, in combination with gemcitabine, paclitaxel, docetaxel, etoposide or vinorelbine [ 9 ]. (ijpsonline.com)
Cyclophosphamide1
- Sure, there were some minor changes, such as no longer recommending cisplatin/etoposide alternating with CAV (cyclophosphamide/doxorubicin/vincristine) for extensive-stage disease, but the basic approaches had remained remarkably unchanged. (jnccn.org)
Concurrent4
- Conclusion: Relative to conventional etoposide/cisplatin and concurrent AHTRT, chemoradiation with PlEo produced similar median and 2-year survival rates and a higher rate of acute esophageal toxicity. (psu.edu)
- I was a 40+ pack year smoker until my dx in 01/07, at which time I quit preparatory to undergoing concurrent radiation and cisplatin/etoposide therapy. (lungevity.org)
- The recommended treatment paradigms have remained virtually unchanged: surgery for stage I disease, cisplatin/etoposide plus concurrent thoracic radiation for limited-stage disease, combination chemotherapy for extensive-stage disease, and prophylactic cranial irradiation (PCI) for those with good response to initial therapy. (jnccn.org)
- We previously reported the efficacy of concurrent cisplatin (Platinol)/etoposide (PE) and radiotherapy in stage IIIB non-small-cell lung cancer in which biopsy confirmation of T4 (noneffusion) or N3 status was required (S9019). (cancernetwork.com)
Ifosfamide and etoposide1
- Her drs are going to use ifosfamide and etoposide. (cancer.org)
NSCLC4
- Many studies have been tried to define the efficacy of combination of oral etoposide with other chemotherapeutic drugs such as cisplatin, 5-FU, and ifosfamide in patients with advanced non-small cell lung cancer (NSCLC). (e-crt.org)
- In this study, we evaluated the effectiveness and toxicities of combination chemotherapy of oral etoposide with intravenous cisplatin and ifosfamide in advanced NSCLC patients. (e-crt.org)
- This study will seek to investigate the efficacy of "Microbiota modulation of the Gut-Lung Axis" combined with chemotherapy in patients with advanced NSCLC. (biomedcentral.com)
- Based on the theoretical basis of "intestinal and lung axis microecological adjustment", combined with traditional platinum-containing two-drug chemotherapy, the efficacy of the new therapy on patients with advanced NSCLC was observed. (biomedcentral.com)
Lymph nodes7
- By 12/07, however, all were growing again and by 07/08 I had mets to my liver, more distant lymph nodes and my 'good' lung. (lungevity.org)
- In 2016, a positron emission tomography scan showed new locations of lymphoma (lymph nodes, spine, and lungs). (cdc.gov)
- Wilms Tumor can spread to lymph nodes in the abdomen and to the lung, and rarely to the liver, but does not spread to the bones, bone marrow, or brain. (hopkinsmedicine.org)
- A subsequent thoracic CT scan was performed to complete the extension report, which showed a polylobed mass extending to the three lobes of the right lung measuring 6 cm, with right interbronchial lymph nodes (Figure 2 ). (hindawi.com)
- CT scan image of the right lung tumor (red arrow) extending to the three lobes with interbronchial lymph nodes. (hindawi.com)
- It may have reached lymph nodes on the same side as your affected lung. (healthline.com)
- Surgery may sometimes be combined with radiation therapy and chemotherapy if the cancer is limited to one lung and nearby lymph nodes. (healthline.com)
Efficacy2
- The combination of irinotecan and cisplatin (IP) has shown at least comparable efficacy to that of etoposide/cisplatin (EP) in patients with extensive-stage small cell lung cancer. (ogologos-giassas.com)
- We conducted a phase II study to evaluate the efficacy and tolerance of EP regimen followed by thoracic radiotherapy (TRT) and IP consolidation chemotherapy in patients with limited-stage small cell lung cancer. (ogologos-giassas.com)
Atezolizumab2
Tumors6
- That wild reproduction causes the formation of tumors that may block air passages in the lung and prevent it from functioning as it should. (healthywomen.org)
- Most solid tumors including lung cancer cells are believed to contain poorly differentiated cancer stem-like cells (CSCs) that initiate tumorigenesis and confer resistance to chemotherapy. (cdc.gov)
- 19 ] Immunohistochemistry and electron microscopy are invaluable techniques for diagnosis and subclassification, but most lung tumors can be classified by light microscopic criteria. (cancer.gov)
- Recent studies have shown a significant relationship between the gut-lung axis microecology and malignant tumors. (biomedcentral.com)
- Lung cancer is one of the malignant tumors with the highest morbidity and mortality in the world. (biomedcentral.com)
- In recent years, a very close relationship between the gut-lung axis microecology and malignant tumors have been found in some studies. (biomedcentral.com)
Radiation2
- Purpose: The combination of cisplatin, ifosfamide, and oral etoposide (PlEo) given concurrently with accelerated hyperfractionated thoracic radiation was studied in patients with limited small-cell lung cancer in a phase II trial to assess response, survival, and toxicity. (psu.edu)
- It had occurred to me some time ago that those of us who were heavy or long time smokers already had compromised lungs and were thus less likely to benefiit from chemo or radiation, but this may go beyond that. (lungevity.org)
Platinum-Based Chemotherapy2
- PURPOSE: To evaluate the impact of the cigarette burden (CB) on the response rate to platinum-based chemotherapy (CT) in patients with lung cancer (LC). (lungevity.org)
- The response rate of platinum-based chemotherapy plus etoposide is more than 60% , and a complete response occurs in about 10% of people. (healthline.com)
Develop lung cancer2
- Class-action lawsuits for employees who develop lung cancer or mesothelioma are neither alien to public awareness, nor are they addressed as seriously as they ought to be. (biospace.com)
- About 15 to 20% of people who develop lung cancer have never smoked or have smoked minimally. (msdmanuals.com)
50mg1
- Radiotherapy was given 3 weeks after the first treatment cycle concurrently with weekly cisplatin 20mg/m(2) on day 1 and etoposide 50mg/m(2) on day 4 within 5-6 weeks, followed by three courses of irinotecan 60mg/m(2) on days 1, 8, and 15 and cisplatin 60mg/m(2) on day 1 of a 4-week cycle. (ogologos-giassas.com)
Combination5
- The combination of cisplatin, ifosfamide, and oral etoposide produced encouraging response rates and median survival duration in patients with response. (e-crt.org)
- Further study of this combination is warranted in comparison with standard cisplatin+etoposide regimen or intravenous etoposide, cisplatin and ifosfamide regimen. (e-crt.org)
- Results of the IMpower133 trial show that administration of pembrolizumab in combination with etoposide and platinum-based therapy gives 2 additional months of overall survival. (askthetrainer.com)
- Benmelstobart plus anlontinib with a chemotherapy combination improved survival outcomes for patients with extensive-stage small cell lung cancer. (curetoday.com)
- This study explores the combination of intestinal microecological regulation and chemotherapy to provide new treatment strategies and basis for lung cancer patients. (biomedcentral.com)
Anlotinib2
- Therapeutic effectiveness of anlotinib combined with etoposide in extensive-stage small-cell lung cancer: a single-arm, phase II trial. (bvsalud.org)
- After successful primary etoposide -based therapy , anlotinib was administered at 12 mg/day on days 1 to 14 of 21-day cycles until disease progression or consent withdrawal. (bvsalud.org)
Exposure9
- The second most common risk factor for lung cancer in the United States is exposure to radon, particularly when combined with cigarette smoking. (healthywomen.org)
- Lung cancer risk increases when radon levels are present at high levels in the home and exposure occurs over a long time, according to the American Cancer Society. (healthywomen.org)
- Another leading cause of lung cancer is on-the-job exposure to carcinogens. (healthywomen.org)
- Hence, our study indicates that a combined exposure to Etoposide and Bevacizumab targets melanoma cells endowed with stem-like properties and might be considered a novel approach to treat cancer-initiating cells. (oncotarget.com)
- Induction of lung cancer stem-like cells by chronic exposure to carbon nanotube s. (cdc.gov)
- Our previous studies have shown that chronic exposure to single-walled carbon nanotube s (SWCNTs) induces malignant transformation of human lung epithelial cells. (cdc.gov)
- Compounding this for victims of occupational lung cancer is the 15-to-35-year development gap between asbestos exposure and onset of lung cancer symptoms. (biospace.com)
- According to the Environmental Litigation Group, P.C. , approximately 37.5% of all occupational lung cancer cases are related to occupational asbestos exposure, even three decades after its carcinogenic properties were proven. (biospace.com)
- The risk of lung cancer increases with combined exposure to toxins and cigarette smoking. (msdmanuals.com)
Doxorubicin1
- Compared with the corresponding parental cells, the SP cells of SWCNT-transformed and H460 cells acquired apoptosis resistance to various chemotherapy including antimycin A, cisplatin, doxorubicin and etoposide. (cdc.gov)
Etiology1
- Etiology references Lung carcinoma is the leading cause of cancer-related death in men and women worldwide. (msdmanuals.com)
Intravenously1
- When Etoposide and Bevacizumab-treated hypoxic cells were injected intravenously into immunodeficient mice revealed a reduced capacity to induce lung colonies, which also appear with a longer latency period. (oncotarget.com)
Mortality6
- And since 1950, the lung cancer mortality rate for American women has increased significantly. (healthywomen.org)
- A recent American Cancer Society study clarified the risk of lung cancer mortality in smokers and former smokers. (health.am)
- examined and compared absolute and relative lung cancer death risk in former smokers as a function of age at cessation.7 In a prospective cohort study with 6 years of follow-up, the absolute risk of lung cancer mortality was compared in individuals who had never smoked and current and former smokers. (health.am)
- For current smokers at age 75, the annual lung cancer mortality is estimated at 1 per 100 for males and 1 per 200 for females. (health.am)
- Lung cancer is the leading cause of cancer-related mortality in the United States. (aacr.org)
- With decreases in smoking rates in recent decades in the United States, lung cancer incidence and mortality have also declined. (aacr.org)
Metastasis3
- He underwent an en bloc resection, and pathological findings concluded to a metastasis of a pulmonary combined small cell carcinoma and adenocarcinoma. (hindawi.com)
- However, intussusception due to a jejunal metastasis of combined lung cancer is extremely rare [ 3 ]. (hindawi.com)
- Indeed, lung cancer metastasis to the bowel is uncommon, reported in less than 1% of patients [ 4 ]. (hindawi.com)
Small14
- These images are a random sampling from a Bing search on the term "Small Cell Lung Cancer. (fpnotebook.com)
- Small cell lung cancer- The recommended dose is 35 mg/m 2 /day for 4 days to 50 mg/m 2 /day for 5 days. (medindia.net)
- My friend was told she has limited stage small cell lung cancer. (cancer.org)
- Two hundred ten patients with extensive stage small cell lung cancer (SCLCa) were enrolled onto this prospective trial, which was partially randomized. (oncolink.org)
- Histological examination revealed a combined lung tumor appearance with a predominant component (80%) consisting of a small cell neuroendocrine carcinoma associated with a solid adenocarcinomatous component, with massive infiltration of the lung, rupture of the visceral pleura, and extension to parietal fat tissue but with free surgical margin at this level and without sarcomatoid component. (hindawi.com)
- It is used in the treatment of non-small cell lung cancer. (ijpsonline.com)
- During 2018, Food and Drug Administration has approved 8 new medications for the non-small cell and small cell lung cancer treatment. (askthetrainer.com)
- Such patients with non-small cell adenocarcinoma and squamous cell lung cancer can receive the sole immunotherapy, without adding chemotherapeutic medications. (askthetrainer.com)
- Immunotherapy is also used in patients with small cell lung cancer. (askthetrainer.com)
- See Small Cell Lung Cancer Treatment Protocols for summarized information. (medscape.com)
- Similar to human non-small cell lung cancer H460 cells, SWCNT-transformed lung epithelial BEAS-2B cells but not its passage-matched control cells formed tumor spheres in stem cell-selective conditions, indicating the existence of lung CSCs. (cdc.gov)
- However, even these patients are at risk of dying from lung cancer (both small and non-small cell types). (cancer.gov)
- Etoposide capsules are a cold-chain medication used for small cell lung cancer that must be stored under refrigeration between 2°C and 8°C (36°F-46°F). A specialty pharmacy reported an error that resulted in a carton of etoposide 50 mg capsules being left out at room temperature overnight for about 12 hours. (pharmacist.com)
- See Small Cell Lung Cancer: Beating the Spread , a Critical Images slideshow, to help identify the key clinical and biologic characteristics of small cell lung cancer, the staging criteria, and the common sites of spread. (medscape.com)
Increases2
- A prolonged administration of etoposide increases its effectiveness on the suggestion that pralonged maintenance of low levels is an important factor in determining its activity. (e-crt.org)
- There is a dose-response relationship for smoking and lung cancer, and the risk for lung cancer increases with smoking duration, number of cigarettes smoked, age at onset of smoking, use of unfiltered cigarettes, tar and nicotine content, and degree of inhalation. (health.am)
Melanoma2
- Etoposide does not influence phenotype of this sub-population of melanoma cells, while a combined treatment with Etoposide and Bevacizumab significantly abolished P1 sphere-forming ability, an effect associated with apoptosis of this subset of cells. (oncotarget.com)
- Hypoxic melanoma cells sorted for VEGF-R2/CD133 positivity also undergo apoptosis when exposed to Etoposide and Bevacizumab. (oncotarget.com)
Decreases2
- etoposide decreases effects of adenovirus types 4 and 7 live, oral by pharmacodynamic antagonism. (medscape.com)
- etoposide decreases effects of influenza virus vaccine quadrivalent, adjuvanted by pharmacodynamic antagonism. (medscape.com)
Type of lung cancer2
- Read on to learn about recent lung cancer statistics and new studies published in the AACR journals on lung cancer screening, early detection, and advances in the treatment of an uncommon type of lung cancer. (aacr.org)
- Your doctors may also perform surgery to take a sample of lung tissue to see which type of lung cancer you have. (healthline.com)
Deaths from lung cancer1
- According to World Health Organization (WHO) statistics, about 1.59 million deaths from lung cancer occur annually throughout the world. (medscape.com)
Treatment of lung cancer3
- In the present study, an attempt was made to achieve better treatment of lung cancer by direct lung delivery of cisplatin microparticulate systems, which helps to localize the drug in the lungs, and also provide sustained action. (ijpsonline.com)
- As a result, intestinal-pulmonary microecological balance could become a new target for the treatment of lung cancer. (biomedcentral.com)
- The results can be promoted and applied to units engaged in the treatment of lung cancer. (biomedcentral.com)
Associated with lung cancer1
- Asbestos is perhaps the best-known industrial substance associated with lung cancer, but there are many cancer-causing substances that people may deal with at work. (healthywomen.org)
Significantly3
- As expected, there was a lower lung cancer death risk seen for those patients who quit smoking earlier in life, and the risk for those who were former smokers was significantly lower than for those who continued to smoke. (health.am)
- If one quit between the ages of 50 and 64, the lung cancer death risk leveled off at the risk attained at the time of quitting until around age 75, when it increased significantly. (health.am)
- Even though smoking is an established risk factor for lung cancer, new research suggests that the rate of physician-patient discussions about lung cancer screening is quite low among current smokers - and has significantly declined in recent years. (aacr.org)
Prostate cancer1
- Lung cancer is the second most common malignancy in both sexes in the United States, exceeded in frequency only by prostate cancer in men and breast cancer in women. (medscape.com)
Oral1
- Treatment consisted of intravenous cisplatin (20 mg/m(2)/day, Day 1-3) and ifosfamide (1,800 mg/m(2)/day, Days 1-3) with Mesna (1,100 mg/m(2)/day, Days 1-3), and oral etoposide (50 mg/m(2)/day, Days 4-17). (e-crt.org)
Drugs2
- Half of people treated with platinum chemotherapy drugs and etoposide live at least 25 to 30 months , and 30% to 35% of people live at least 5 years. (healthline.com)
- Lungs provide a large surface area and hence can be explored as a potential site for the systemic delivery of drugs. (ijpsonline.com)
Extensive-stage1
- This lack of progress is epitomized by the continued use of platinum/etoposide regimens as standard first-line chemotherapy for patients with both limited- and extensive-stage disease. (jnccn.org)
Biopsy1
- Biopsy with histological examination of the tumor tissue remains the gold standard for diagnosis of cancer, as it allows precise examination of atypical cells and forms the basis for the subsequent lung cancer treatment. (askthetrainer.com)
Smokers4
- Since smoking cessation efforts in the United States in the past few decades have been quite successful, lung cancer is now very often a disease of former smokers. (healthywomen.org)
- compared with "never smokers," those who smoke tobacco have roughly a 20-fold higher relative risk of developing lung cancer. (aacr.org)
- The study reported that the prevalence of lung cancer screening discussions between physicians and current smokers dropped from 12 percent in 2012 to 8.7 percent in 2017. (aacr.org)
- Following multivariable analysis, the researchers determined that lung cancer screening discussions had no association with current smokers' attempts to quit smoking in the past year, or with their intent to stop smoking in the next six months. (aacr.org)