• dose
  • Reproduction studies in rats and rabbits have shown that loperamide administered in doses up to 30 times the human therapeutic dose does not interfere with fertility. (drugs.com)
  • Reproduction studies in rats and rabbits have shown that loperamide administered in doses up to 30 times the human therapeutic dose did not cause harm to the offspring, {05} {36} or produce teratogenic effects. (drugs.com)
  • {14} {25} {29} {30} However, in a pre- and post-natal study, loperamide administered to female nursing rats at a dose of 40 mg per kg of body weight caused a decrease in pup survival. (drugs.com)
  • Consuming a higher dose of loperamide than recommended quantity or when recommended amount of loperamide is taken with other medicines that may interact with it are the main reasons behind serious heart problems. (medindia.net)
  • 16) Depending on the presentation, opioid receptor agonists such as loperamide , antispasmodics such as hyoscine, cimetropium, pinaverium, and antidepressants such as low-dose tricyclic antidepressants and selective serotonin reuptake inhibitors may be prescribed. (thefreedictionary.com)
  • For liquid forms of loperamide, use a syringe to measure each dose as this gives a more accurate measurement than household teaspoons. (pharmasave.com)
  • Do not use more than the recommended dose of loperamide, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. (drugs.com)
  • opioid
  • It is manufactured by the McNeil Consumer Healthcare Division of McNeil PPC, Inc. Loperamide is a μ-opioid receptor agonist that works in the intestines. (wikipedia.org)
  • doses
  • Food and Drug Administration has issued warning for Loperamide (Imodium) as higher doses of the drug can cause severe heart problems which may lead to death. (medindia.net)
  • symptomatic
  • Loperamide treatment is not used in symptomatic C. difficile infections, as it increases the risk of toxin retention and precipitation of toxic megacolon. (wikipedia.org)
  • adverse
  • A review of loperamide in children under 12 years old, and found that serious adverse events occurred only in children under 3 years old. (wikipedia.org)
  • Children
  • Loperamide is not recommended for use in children up to 6 years of age {04} {05} {25} {29} {30} unless directed by a physician. (drugs.com)
  • Children, especially those under 3 years of age, are more susceptible to the opiate-like effects (CNS effects) of loperamide. (drugs.com)
  • The use of loperamide in children under 2 years is not recommended. (wikipedia.org)