• One of the most striking results from the expression analysis was that the drought sensitive plants were characterised by having approximately twice the number of differentially expressed transcript tags than the tolerant plants after drought. (biomedcentral.com)
  • Transcriptional analysis of ACBP-deficient parasites revealed differentially expressed genes involved in a wide range of biological processes such as lipid metabolism, posttranslational modification, and membrane biogenesis. (biomedcentral.com)
  • In addition, reviewer#3 concern on confidence for genes reported as differentially expressed should be addressed as suggested. (peerj.com)
  • The identification of genes that were differentially expressed in the shell-forming mantle tissue and the comparison of the genotypes with the phenotypes under consideration of the inheritance of the characters is an appropriate approach to identify candidate genes that may be involved in the genetic mechanism resulting in the observed phenotypes. (peerj.com)
  • Unfortunately, none of the transcripts that match with at least one of the elongated tags that lie in close proximity to the supergene was found in the list of differentially expressed transcripts with phenotype-consistent variants. (peerj.com)
  • Deep cDNA sequencing demonstrated that both wild-type and mutant alleles were expressed . (massgenomics.org)
  • a loblolly pine (pinus taeda l.) cdna with properties of a nonspecific lipid transfer protein (nsltp) is reported. (liverpool.ac.uk)
  • two genes preferentially expressed in differentiating xylem of loblolly pine (pinus taeda l.) were cloned from cdna and genomic libraries and designated ptx3h6 and ptx14a9. (liverpool.ac.uk)
  • Canine ortholog cDNA sequence was cloned and verified using RPE/choroid 5′- and 3′-RACE. (upenn.edu)
  • A selected set of homologous sequences are listed below, with sequence identity being calculated in comparison to the human reference sequence. (wikipedia.org)
  • After Blast analysis within GenBank, 64% could be identified, 21% were homologous to unannotated expressed sequence tag (EST) or genomic sequences, and 15% were novel. (appliedbioinfo.com)
  • Through de novo transcriptome assembly with the RNA-seq reads from whole organ samples of C. virgata at the germination stage (2 days after germination, DAG), early young development stage (8 DAG), young development stage (17 DAG), and adult development stage (28 DAG), we identified 21,589 unified transcripts (contigs) and found that 19,346 and 18,156 protein-coding transcripts were homologous to those in rice and Arabidopsis , respectively. (frontiersin.org)
  • Inclusion of desired sequences between recombination "arms" that are homologous to the region flanking the DSB allows the "knock in" of the transgene. (genecopoeia.com)
  • C6orf58 is a human gene located at locus 6q22.33 of chromosome 6 and encodes for UPF0762, a protein which is subsequently secreted after cleavage of a signal peptide. (wikipedia.org)
  • Transposable elements (TEs) and satellite DNAs, two major categories of repetitive sequences, are expected to accumulate in non-recombining genome regions, including sex-linked regions, and contribute to sex chromosome evolution. (bvsalud.org)
  • This study improves our understanding of the repetitive sequence organization of H. scandens genome and provides a basis for further analysis of their chromosome evolution process. (bvsalud.org)
  • 2010). This development grew out of work showing that adeno associated virus (AAV) typically integrates into one genomic locus: PPP1R12C, on chromosome 19. (genecopoeia.com)
  • Preliminary analyses using 454 transcriptome and Bacterial Artificial Chromosome (BAC) sequences from three Heliconius species highlighted a cluster of genes within each region showing relatively higher rates of sequence evolution. (biomedcentral.com)
  • The Web site "www.artichokegenome.unito.it" hosts all the available genomic sequences, together with their structural/functional annotations and project information are presented to users via the open-source tool JBrowse, allowing the analysis of collinearity and the discovery of genomic variants, thus representing a one-stop resource for Cynara cardunculus genomics. (researchgate.net)
  • Plant intracellular nucleotide binding and leucine-rich repeat proteins (NB-LRR, NLRs) function as immune receptors to detect microbial pathogens directly or indirectly. (ubc.ca)
  • While there are 3 splice variants of C6orf58, only one encodes a good protein. (wikipedia.org)
  • The immunoglobulin-like transcript (ILT) comprise a family of activating and inhibitory type immunoreceptors whose genes are located in the same locus that encodes killer cell Ig-like receptors (KIR). (kactusbio.com)
  • SUSA2 encodes an F-box protein Actin-Related Protein 8 (ARP8) and SUSA3 encodes the chaperone protein HSP90.3. (ubc.ca)
  • The transcript is predominantly expressed in RPE/choroid and encodes bestrophin, a 580-amino acid protein of 66 kDa. (upenn.edu)
  • By integrating expression quantitative trait locus (eQTL) and genome-wide association study (GWAS) data, we demonstrate that long-range chromatin interactions between variant regulatory elements and their target genes contribute to variations in gene expression, metabolic phenotypes, and agronomic traits. (nature.com)
  • 1,2 However, recent work has shown that chromatin, the RNA-DNA-protein complex that controls chromosomal organization and gene expression in mammalian nuclei, 3-5 blocks access of Cas9 to certain DNA target sites in vitro 6-8 and in mammalian cells. (aip.org)
  • Entrez is NCBI's primary text search and retrieval system that integrates the PubMed database of biomedical literature with 38 other literature and molecular databases including DNA and protein sequence, structure, gene, genome, genetic variation and gene expression. (nih.gov)
  • BACKGROUND: Long terminal repeat (LTR)-retrotransposons (LTR-RTs) are ubiquitous and make up the majority of nearly all sequenced plant genomes, whereas their pivotal roles in genome evolution, gene expression regulation as well as their epigenetic regulation are still not well understood, especially in a large number of closely related species. (bvsalud.org)
  • So, the "Rosa26" locus has since been used as a transgene insertion site that causes no apparent adverse effects on fitness, and permits stable gene expression. (genecopoeia.com)
  • In order to clarify the biological and pharmacological mechanisms of O. sinensis , we carried out the genome sequencing of H. sinensis, anamorph of O. sinensis , for the first time, described the annotation and gene expression, and analyzed the complete sequencing data (Li et al. (springeropen.com)
  • These transcript tags were annotated with gene ontology (GO) terms. (biomedcentral.com)
  • The best-aligned sequences were annotated with gene ontology groups. (frontiersin.org)
  • and 4) Expression of a protein from a particular species, such as mice, in an orthologous organism such as humans. (genecopoeia.com)
  • To assess whether this pattern is true of nematodes in general, we have used genome sequence to compare two nematode species that last shared a common ancestor approximately 300 million years ago: the model C. elegans and the filarial parasite Brugia malayi . (biomedcentral.com)
  • The same search parameters were applied to reveal the SSR content of 14 other plant species for which genome sequence is available. (researchgate.net)
  • Three genes from each locus with the highest average pairwise ω values were amplified from additional Heliconius species and races. (biomedcentral.com)
  • DEFINITION line contains species name and protein name. (nig.ac.jp)
  • The results confirmed that the MOGAT1, MOGAT3/g.A229G, and MOGAT3/g.G1627A locus are strong candidate genes that could be considered molecular markers for growth traits in cattle breeding. (copernicus.org)
  • Ratios of nonsynonymous to synonymous nucleotide changes (ω) were used to test for selection, as a means of identifying candidate genes within each locus that control wing pattern. (biomedcentral.com)
  • Tests of selection reveal a cluster of candidate genes in each locus, suggesting that weak directional selection may be occurring within a small region of each locus, but coding changes alone are unlikely to explain the full range of wing pattern diversity. (biomedcentral.com)
  • Many genetic variations outside protein-coding regions are associated with maize phenotypes. (nature.com)
  • Genome editing has many applications, including gene knock out, gene tagging, and correction of genetic defects, to name a few. (genecopoeia.com)
  • Protein-coding change is one possible genetic mechanism underlying the evolution of adaptive wing colour pattern variation in Heliconius butterflies. (biomedcentral.com)
  • In chapter 2, by using CRISPR/Cas9 gene editing, genetic analysis and biochemical assays, I identified the differential pairings of typical NLR receptor SOC3 with atypical NLR proteins CHS1 or TN2 to guard the homeostasis of the E3 ligase SAUL1. (ubc.ca)
  • Sequence homology is an indication of the genetic relatedness of different organisms and gene function. (lookformedical.com)
  • 2: autosomal recessive), and an alphabet based on the order of discovery of linkage to a specific, certain genetic locus or a new disease gene. (medscape.com)
  • However, in the mid 1990s, other proteins were also found to accumulate in the abnormal muscle fibers, and molecular genetic studies revealed several chromosomal loci. (medscape.com)
  • Among them, 52 were derived from six retrotransposon long terminal repeats loci in the B. cinerea genome, 13 were from intergenic regions of 10 loci, and eight were mapped to five protein-coding genes. (genomeweb.com)
  • TERMINAL REPEAT SEQUENCES flank both ends of another sequence, for example, the long terminal repeats (LTRs) on RETROVIRUSES. (lookformedical.com)
  • Two studies have identified quantitative trait loci (QTLs) for traits related to persistence in red clover. (biomedcentral.com)
  • The system is based on the highly sensitive and quantitative Nanoluciferase that is conditionally expressed upon reporter-transcript editing. (cancerindex.org)
  • Rapid and comprehensive analysis of putative proteinous allergens ( allergenome ) by applying such a proteomic strategy … With allergenomics, we can not only detect and assign the putative allergens (proteins specifically interacting with IgE antibodies in a patient's blood) in a short time, but also analyze the quantitative and qualitative change of the antigens, depending on the surroundings and environmental conditions of an allergenic causative. (genomicglossaries.com)
  • identification of quantitative trait loci influencing wood specific gravity in an outbred pedigree of loblolly pine. (liverpool.ac.uk)
  • The chromosomal locations and number of exons from protein prenyltransferase genes in the major eukaryotic model organisms are shown in Table 2 . (biomedcentral.com)
  • The authors undertook systematic sequencing of U2AF1 exons in 150 MDS cases, and found that 8.7% had mutations at Ser34. (massgenomics.org)
  • PCR analysis of exon utilization reveals massive alternative mRNA splicing of Sec31B, with just 16 exons being constitutively utilized in all transcripts. (biologists.com)
  • Sequences of DNA in the genes that are located between the EXONS. (lookformedical.com)
  • All exons and the flanking splice junctions were screened by direct sequencing. (upenn.edu)
  • There were more reads in these libraries than in cultured B. cinerea control libraries, with sequences matching the B. cinerea genome, but not Arabidopsis or tomato genomes. (genomeweb.com)
  • 5 ]. For Genomes , it collects genome sequences and also supports Blast, querying by using a chr ID in publication and databases such as Sc0000024 (only for lancelet), chr1 , chr22 and so on. (bucm.edu.cn)
  • Both TALEN and CRISPR are chimeric endonucleases that initiate double-strand break (DSB) formation at virtually any target sequence in genomes, leading to mutagenesis. (genecopoeia.com)
  • UPF0762 shows high homology in primates and orthologous proteins can be traced back as far as trichoplax adhaerens. (wikipedia.org)
  • Comparison of B. malayi BAC-end genome survey sequence to C. elegans also revealed a bias towards intrachromosome rearrangements. (biomedcentral.com)
  • Automatic comparisons of data from expressed sequence tags (ESTs) with genes (for example using the program Acembly, for which the results are available from the NCBI AceView server [ 2 ]) shows that all the human protein prenyltransferase genes have multiple alternative splice variants. (biomedcentral.com)
  • some of the predicted transcripts may be derived from missplicing rather than being real splice variants. (biomedcentral.com)
  • Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region. (cancerindex.org)
  • A collection of different allotypes or allelic protein variants, a new type of protein library. (genomicglossaries.com)
  • Alternative splicing of this gene results in multiple transcript variants. (creativebiomart.net)
  • The α subunits of protein prenyltransferases consist of tetratricopeptide repeats and are part of the tetratricopeptide repeat superfamily [ 5 ], which also includes functionally diverse proteins involved in transcription, co-chaperoning, protein transport, cell-cycle control and phosphorylation. (biomedcentral.com)
  • This de novo assembly of a red clover transcriptome from leaf material of droughted and non-droughted plants provides a rich source for gene identification, single nucleotide polymorphisms (SNP) and short sequence repeats (SSR). (biomedcentral.com)
  • In vitro analysis revealed that a putative switch-protein kinase regulator, RsbW, is capable of interacting directly with σ 66 , as well as phosphorylating its own antagonist, RsbV1, rendering it inactive. (plos.org)
  • Here we determine whether 38 putative genes within two major Heliconius patterning loci, HmYb and HmB , show evidence of positive selection. (biomedcentral.com)
  • Format of DAD entries The standard format of DAD is almost the same as that of the DDBJ nucleotide sequence database except for those described below. (nig.ac.jp)
  • It is also called nucleotide sequence. (lookformedical.com)
  • The presence of a stop codon in exon 13 generates two families of Sec31B gene products (each displaying additional patterns of mRNA splicing): a group of full-length proteins (hereafter referred to as Sec31B-F) and also a group of truncated proteins (hereafter referred to as Sec31B-T), distinguished by their utilization of exon 13. (biologists.com)
  • 2014). Where annotations were not present or were different, the online Softberry server (http://linux1.softberry.com/berry.phtml) was used to predict mRNA and protein sequences using the FGNESH+ prediction algorithm (Solovyev et al. (molquest.com)
  • In breast carcinoma specimens, lymph node status was significantly associated with HIF-1α TAG mRNA levels ( P = 0.037). (biomedcentral.com)
  • Significant statistical association was found between tumour grade and HIF-1α TAG ( P = 0.048), and total HIF-1α ( P = 0.048) mRNA levels. (biomedcentral.com)
  • Univariate analysis showed that high HIF-1α TAG mRNA levels correlated with shortened metastasis free survival ( P = 0.01). (biomedcentral.com)
  • Our results show for the first time that mRNA expression of a HIF-1α TAG splice variant reflects a stage of breast cancer progression and is associated with a worse prognosis. (biomedcentral.com)
  • Gene structures and chromosomal locations of human protein prenyltransferase subunit genes. (biomedcentral.com)
  • This study provides evidence that a switch-protein kinase regulatory network controls availability of σ 66 , the main sigma subunit for transcription in Chlamydia . (plos.org)
  • DUF781 is the singular domain of the protein and spans 318 of the protein's 330 amino acids. (wikipedia.org)
  • A signal peptide, which is predicted to direct the protein to the endoplasmic reticulum for secretion, is cleaved from the first 20 amino acids of the peptide sequence. (wikipedia.org)
  • Analysis of the mutated protein sequence for a signal peptide shows cleavability at the regular amino acid 20 is lost. (wikipedia.org)
  • We have identified a cytosolic acyl-CoA binding protein, with highly conserved amino acid residues and a typical acyl-CoA binding domain in N. caninum . (biomedcentral.com)
  • DDBJ Amino Acid Sequence Database (DAD) Release 91.0, Sep. (nig.ac.jp)
  • Introduction This is release 91.0 of DDBJ Amino Acid Sequence Database (DAD). (nig.ac.jp)
  • An amino acid sequence begins from the next line of "BEGIN. (nig.ac.jp)
  • Following the amino acid sequence, there is a double slash (//) which means the end of the entry. (nig.ac.jp)
  • Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories. (lookformedical.com)
  • HIF-1α protein is composed of 826 amino acids [ 5 ]. (biomedcentral.com)
  • In the middle section of HIF-1α lies a Pro-Ser-Thr oxygen-dependent degradation domain (ODDD, amino acids 401 to 603), which is responsible for the stability of the HIF-1α protein [ 12 ]. (biomedcentral.com)
  • This rejection mechanism is initiated by a ligand-receptor interaction and is genetically controlled by a single polymorphic locus, called the S -locus [ 4 ]. (biomedcentral.com)
  • Here, we characterize epigenetic features of active promoter proximal regions and candidate distal regulatory elements to construct high-resolution chromatin interaction maps for maize via long-read chromatin interaction analysis by paired-end tag sequencing (ChIA-PET). (nature.com)
  • Meanwhile, two plant defense marker genes, which do not contain target sites for the fungal sRNAs, were highly upregulated, leading the researchers to conclude that suppression of some but not all genes is a result of sequence-specific sRNA interaction and not cell death within infected lesions. (genomeweb.com)
  • HIF-1α is known to be mainly post-transcriptionally regulated by protein ubiquitination and interaction with the Von Hippel-Lindau tumour suppressor protein, and then degraded by the proteasome. (biomedcentral.com)
  • To address that issue, translatome analysis [ 18 ] has been applied to identify sex-specific genes expressed during pollination, but this strategy needed large amounts of tissues from a transgenic line expressing tagged ribosomes in pollen and fine techniques of biochemistry. (biomedcentral.com)
  • Next, the scientists evaluated the impact the B. cinerea sRNAs had on plant immunity, generating transgenic Arabidopsis plants that ectopically expressed the three sRNAs under investigation. (genomeweb.com)
  • Most NLRs guard host proteins that are the direct targets of pathogen effectors. (ubc.ca)
  • It is well known that proteins from both classes of the plant's immune system-PRRs and NLRs-rely on interactions between multiple host proteins to neutralize an invading pathogen. (frontiersin.org)
  • Immunocytochemistry of normal canine retina demonstrated specific localization of protein to the RPE basolateral plasma membranes. (upenn.edu)
  • Limb-girdle muscular dystrophy (LGMD) protein defects occur in several pathways involved in the biologic function of muscle and can be divided into groups based on cellular localization. (medscape.com)
  • This clone was engineered to express the complete ORF with an expression tag. (origene.com)
  • Scope includes mutations and abnormal protein expression. (cancerindex.org)
  • The BioProject database is a searcheable collection of complete and incomplete (in-progress) large-scale molecular projects including genome sequencing and assembly, transcriptome, metagenomic, annotation, expression and mapping projects. (nih.gov)
  • Expression of hemagglutinin-epitope tagged MPK2, MPK1, and WAK was reduced when they were coexpressed with the corresponding [sRNAs] but not when coexpressed with Arabidopsis [microRNA] miR-395, which shared no sequence similarity," they wrote in Science . (genomeweb.com)
  • The recombinant NcACBP protein was expressed to verify the binding activities of NcACBP in vitro , and the heterologous expression of NcACBP in Δacbp yeast in vivo . (biomedcentral.com)
  • In addition, transgenes inserted in order to be expressed from either the native PPP1R12C or an exogenous promoter displayed consistent levels of expression over many cell divisions. (genecopoeia.com)
  • Expression of the canine gene transcripts and protein was analyzed by Northern and Western blotting and immunocytochemistry. (upenn.edu)
  • To reduce the risk of analyzing cell line- pathway can be divided into distinct stages based on the specific features, we used several representative cell lines for recombination status of the Ig genes and on the expression each of four major stages in B cell development: pro-B, pre-B, pattern of surface markers and the presence of intracellular proteins [1- 6]. (lu.se)
  • 7- 9 All reported mutations are single nucleotide alterations leading to splice site, missense, nonsense, or frameshift mutations, or intra-exonic deletions and insertions of up to four nucleotides, which have been detected through exonic PCR amplifications and sequencing. (bmj.com)
  • Because the molecular basis of the parent of origin effects in PGL1 is unknown, it is unclear whether transmissions of mutations in SDHC , the protein product of which couples with that of SDHD and forms the membrane spanning domain of mitochondrial complex II, also shows any parent of origin effects. (bmj.com)
  • Cas9 activity, determined by insertion deletion mutations, was restored in Gal4P65-expressing cells, while no CRISPR enhancement was observed with UNC1999 treatment. (aip.org)
  • These results do not support a major role for transcriptional transitions in the time of onset of DNA methylation in the oocyte, but suggest a model in which sequences least dependent on chromatin remodelling are the earliest to become permissive for methylation. (biomedcentral.com)
  • Hypoxia stabilises HIF-1α protein by relaxing its ubiquitin-proteasome degradation [ 12 ] and affects subcellular localisation, DNA binding capacity and transcriptional activation function of the HIF-1 complex. (biomedcentral.com)
  • 4 ]. For ESTs , it stores Expressed sequence tags to supports Blast, but also provides obtaining sequences by EST-ID in databases, For example est_xb_1526 . (bucm.edu.cn)
  • The maps indicate that chromatin loops are formed between regulatory elements, and that gene pairs between promoter proximal regions tend to be co-expressed. (nature.com)
  • We also tested DNA-binding, transiently expressed activation-associated proteins (AAPs) that are known to support an open, transcriptionally active chromatin state. (aip.org)
  • Our results demonstrate the use of DNA-binding, activator-associated fusion proteins as an effective method to enhance Cas9 editing within polycomb-repressed chromatin. (aip.org)
  • B-cell translocation gene 4, cullin 1, MCF.2 transforming sequence, a locus similar to snail soma ferritin, and three unidentified genes were, indeed, preferentially expressed in the oocyte, even though most were also highly expressed in testis. (appliedbioinfo.com)
  • Sec31B is widely expressed and enriched in cerebellum and testis. (biologists.com)
  • Genes preferentially expressed in bovine oocytes revealed by subtractive and suppressive hybridization. (appliedbioinfo.com)
  • In total, two statistical methods (general linear model (GLM) and PROC MIXED) were used to identify an association between gene locus and growth traits. (copernicus.org)
  • When expressed as a fusion protein with eYFP in cultured cells, Sec31B-F associates with the endoplasmic reticulum and with vesicular-tubular clusters, displays restricted intracellular movement characteristic of COPII vesicle dynamics, co-distributes on organelles with Sec13, Sec31A and Sec23 (markers of the COPII coat), and concentrates with ts045-VSV-G-CFP (VSV-G) when examined early in the secretory pathway or after temperature or nocodazole inhibition. (biologists.com)
  • An 83 kb region flanking the gene for Bm-mif-1 (macrophage migration inhibitory factor, a B. malayi homolog of a human cytokine) was sequenced. (biomedcentral.com)
  • The protein encoded by this gene binds to several chemokine receptors, including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). (creativebiomart.net)
  • CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. (creativebiomart.net)
  • The HIF-1 protein is composed of two HIF-1α and HIF-1β/aryl hydrocarbon receptor nuclear translocator (ARNT) subunits. (biomedcentral.com)
  • Recombinant Human LILRB2/CD85d/ILT4 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln22-His458. (kactusbio.com)
  • CCL3L1 MS Standard C13 and N15-labeled recombinant protein (NP_066286) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. (creativebiomart.net)
  • The subtracted library was characterized by sequencing 185 random clone inserts, representing 146 nonredundant genes. (appliedbioinfo.com)
  • The molecular sequence of this clone aligns with the gene accession number as a point of reference only. (origene.com)
  • Interestingly, functionally redundant SNIPER1 and SNIPER2 can control the protein levels of diverse sNLRs and the interactions between SNIPER1 and sNLRs appear to be through the common nucleotide-binding (NB) domains of sNLRs. (ubc.ca)
  • The genes encoding CaaX protein prenyltransferases are considerably longer than those encoding non-CaaX subunits, as a result of longer introns. (biomedcentral.com)
  • COX, responsible for the reduction of oxygen to water, consists of three catalytic core subunits (Cox1, Cox2, and Cox3), each derived from a mitochondrial gene and of 8-10 additional structural subunits that are expressed from nuclear genes. (life-science-alliance.org)
  • Following B. cinerea infection in Arabidopsis , transcript levels of several of the sRNAs' predicted targets were suppressed. (genomeweb.com)
  • ILT4, also known as LIR-2 and LILRB2, is a type I transmembrane protein expressed primarily on monocytes and dendritic cells (DC). (kactusbio.com)
  • The genomic organization of the human genes that encode protein prenyltransferases is shown in Figure 1 . (biomedcentral.com)
  • The transcripts were degraded throughout preimplantation development and were not compensated for by embryonic transcription after the morula stage. (appliedbioinfo.com)
  • The region of DNA which borders the 3' end of a transcription unit and where a variety of regulatory sequences are located. (lookformedical.com)
  • Nucleotide sequences, usually upstream, which are recognized by specific regulatory transcription factors, thereby causing gene response to various regulatory agents. (lookformedical.com)
  • The large proteoglycan molecules made up of protein cores, and GAG branches are secreted by cells and constitute a significant fraction of the extracellular matrix of connective tissue. (medscape.com)
  • Kent and Zahler [ 9 ] compared 8.1 megabases (Mb) of fragmentary C. briggsae sequence derived from sequenced cosmid clones to C. elegans and derived a mean syntenic fragment length of 8.6 klobases (kb), or approximately 1.8 genes (there is one gene per 5 kb in C. elegans ) [ 13 ]. (biomedcentral.com)
  • MicroRNAs (miRNAs) are small regulatory non-coding RNAs, resulting from the cleavage of long primary transcripts (pri-miRNAs) in the nucleus by the Microprocessor complex generating precursors (pre-miRNAs) that are then exported to the cytoplasm and processed into mature miRNAs. (mdpi.com)
  • The Alu sequence family (named for the restriction endonuclease cleavage enzyme Alu I) is the most highly repeated interspersed repeat element in humans (over a million copies). (lookformedical.com)
  • Further characterization showed that susa2-2 only suppresses the autoimmunity mediated by either CHS1-SOC3 or TN2-SOC3 paired NLR proteins, indicating that SUSA2 is specifically involved in NLR protein SOC3-mediated immunity. (ubc.ca)
  • The NcACBP recombinant protein was able to specifically bind acyl-CoA esters in vitro . (biomedcentral.com)
  • As a positive regulator of plant immunity, E3 ligase SAUL1 is guarded by NLR protein SOC3. (ubc.ca)
  • Several well-known oocyte-specific genes were represented, including growth differentiation factor 9, bone morphogenetic protein 15, or the zona pellucida glycoprotein genes. (appliedbioinfo.com)
  • The list of proteins below is not a comprehensive listing of UPF0762 orthologs. (wikipedia.org)
  • Potential C. elegans orthologs for II of the 12 protein-coding genes predicted in the B. malayi sequence were identified. (biomedcentral.com)
  • The prognostic relevance of HIF-1α protein overexpression has been shown in breast cancer. (biomedcentral.com)