• AQPs
  • The aquaporins (AQPs) are a family of water-transporting channels that are expressed widely in mammalian fluid-transporting epithelia and endothelia. (arvojournals.org)
  • 1 2 3 4 5 6 Because of this expression pattern, it has been proposed that AQPs play a role in intraocular pressure regulation, corneal and lens transparency, and vision. (arvojournals.org)
  • DHFZT ameliorated the pulmonary and intestinal edema and injury induced by SAP via the upregulation of different AQPs in lung and intestine, and suppressed TNF-α, IL-6 expression and enhanced IL-10 expression. (biomedcentral.com)
  • Choroid plexus epithelial cells (CPECs) secrete most of the CSF through poorly understood mechanisms that involve aquaporins (AQPs) and various solute transport proteins like the Na+-K+-2Cl- cotransporter 1 (NKCC1). (wright.edu)
  • Transmembrane fluxes of water via specialized water channels, called aquaporins (AQPs), facilitate the changes of volume and shape, which additionally require a complex interplay between the plasma membrane and the cytoskeleton. (diva-portal.org)
  • pores
  • Each of the aqueous pores of AQP9 has independent water permeabilization activity, and the basic structure constituting these water pores is an α-helix of 6 times across the cell membrane. (creative-biogene.com)
  • Here, I will summarize our current knowledge of the involvement of aquaporin-formed pores and tight junctions in epidermal water homeostasis - as well as in other functions - and their putative roles in skin dryness. (springer.com)
  • Function
  • I supervise a number of PhD students' research involving the study of the structure and function of aquaporin water channels as well as continued work on GPCRs. (wlv.ac.uk)
  • Regulation
  • Aquaporin 1 and 5 expression decreases during human intervertebral disc degeneration: novel HIF-1-mediated regulation of aquaporins in NP cells. (wlv.ac.uk)
  • Conner AC, Bill RM and Conner MT. Aquaporin Regulation. (wlv.ac.uk)
  • Although its regulation has been commonly attributed to aquaporins activity, osmotic adjustment and the toxic effect of Na+ and Cl- have also a main role in the whole process. (jove.com)

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  • NaCl
  • With 100 mM NaCl, net assimilation was much higher in the GmPIP1;6 -Oe and growth was enhanced relative to WT. (beds.ac.uk)
  • pulmonary
  • Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. (wikipedia.org)
  • The aim of present study was to investigate whether DHFZT could relieve pulmonary and intestinal injury by regulating aquaporins after SAP induced by sodium taurocholate in rats. (biomedcentral.com)
  • accumulation
  • Finally, the functionality of aquaporins was assessed with dye accumulation test in presence and absence of AQP inhibitors in hypotonic and isotonic solutions. (arvojournals.org)
  • Lastly, the aquaporin inhibitors significantly reduced the dye accumulation to cells that were bathed in hypotonic solution. (arvojournals.org)
  • rats
  • Agren J, Zelenin S, Hakansson M, Eklof AC, Aperia A, Nejsum LN, Nielsen S, Sedin G (2003) Transepidermal water loss in developing rats: role of aquaporins in the immature skin. (springer.com)
  • conductance
  • GmPIP1;6 -Oe plants did not have higher root hydraulic conductance ( L o ) under normal conditions, but were able to maintain L o under saline conditions compared to WT which decreased L o . (beds.ac.uk)