• Delivers a concentrated, stable source of Phosphatidyl Choline, the most predominant phospholipid in the brain and liver, which plays an essential and regenerative role in helping to maintain healthy liver and brain function. (procapslabs.com)
  • Phosphatidyl Choline Liver and Brain Benefits provides a concentrated, stable source of the most important phospholipids essential for healthy brain and liver function. (procapslabs.com)
  • We focus on phosphatidyl choline (PC), since it is the predominant phospholipid in both the brain and liver and is now recognized by the FDA as an essential nutrient because of its important role and scarcity in our diet. (procapslabs.com)
  • In short, there is no more important building block to support and promote the health of our brain and liver than phosphatidyl choline (PC). (procapslabs.com)
  • Choline can be synthesized from phosphatidylcholine via the cytidine-diphosphate (CDP) pathway. (nih.gov)
  • Low dietary choline loweres methionine formation and causes a marked increase in S-adenosylmethionine utilization in the liver. (nih.gov)
  • Phosphatidylcholine (PC) is a phospholipid that is obtained from the nutritional amalgam lecithin , which encloses fatty acids, phosphate as choline. (herbs2000.com)
  • In fact, choline present in phosphatidylcholine is essential for the metabolism or chemical activity of fatty acids as well as for transporting fats via the cells. (herbs2000.com)
  • In addition, this nutritional phosphatidylcholine also has the potential to facilitative the treatment of bipolar disorder, a medical condition that is related to poor activity of choline in the brain. (herbs2000.com)
  • Phosphatidyl Choline (also referred to as phosphatidylcholine) is a preferred form of choline derived directly from lecithin. (lifestylemarkets.com)
  • Phosphatidylcholine, a source of choline, supports healthy brain and nerve function as a precursor to neurotransmitter acetylcholine. (lifestylemarkets.com)
  • High content of choline along with nutrient density makes yolk as best source of nutrient which may boost egg phosphatidylcholine market size. (gminsights.com)
  • Rarely, people who take pure choline can develop a fish odor- this is due to a liver enzyme deficiency that impairs choline metabolism. (kellymom.com)
  • The form of choline in lecithin (phosphatidylcholine) should not cause this problem. (kellymom.com)
  • People with liver failure may develop this deficiency, as may those with normal livers who take more than 20 grams of (pure) choline per day. (kellymom.com)
  • Choline is found in such foods as egg yolks and liver as phosphatidylcholine, according to Balchem. (foodbusinessnews.net)
  • However, the form of choline seems to matter, with greatest risk of elevated TMAO levels seen for free choline (i.e., choline bitartrate) and low to no risk found with forms of choline such as phosphatidylcholine or lecithin. (consumerlab.com)
  • TMAO is produced from choline by the actions of microbes in the gut, turning choline into TMA, which is then absorbed and is converted by enzymes in the liver into TMAO. (consumerlab.com)
  • On the other hand, supplementing with phosphatidylcholine (another form of choline and a major component of lecithin) or eating foods high in phosphatidylcholine (such as liver, beef and pork) does not appear to significantly raise TMAO levels in the blood or urine. (consumerlab.com)
  • Similarly, eating one to two eggs (a dietary source of lecithin, yielding about 250 mg of choline mainly as phosphatidylcholine) per day can temporarily increase TMAO levels at one hour after intake, but levels appear to return to normal after about two hours and fasting levels (that is, levels at least 12 hours after eating) do not appear to be elevated. (consumerlab.com)
  • But does phosphatidylcholine, a form of choline (and the main form in eggs), have similar effects on TMAO levels? (consumerlab.com)
  • Most recently, my article entitled "Nonalcoholic Fatty Liver Disease: A Silent Epidemic of Nutritional Imbalance" contained a major section on the role of dietary choline in protecting against fatty liver disease, which itself is a powerful and independent risk factor for heart disease. (westonaprice.org)
  • The authors argue that dietary choline, found mostly as phosphatidylcholine, enters the intestine where our gut bacteria convert it to free choline and then to trimethylamine, a gas that smells like rotting fish. (westonaprice.org)
  • Studies in humans have shown that neither phosphatidylcholine nor choline-rich foods produce detectable increases in trimethylamine. (westonaprice.org)
  • Choline chloride and choline stearate led to the production of large amounts of trimethylamine, but lecithin (phosphatidylcholine), the main form of choline found in food, led to only a small increase. (westonaprice.org)
  • They found that 60 percent of free choline and 30 percent of carnitine, another potential precursor, was excreted in the urine as one of these two products, but that neither betaine nor phosphatidylcholine converted to either product at all. (westonaprice.org)
  • Choline-rich foods like liver and eggs did not produce any increase in urinary trimethylamine or TMAO over control levels. (westonaprice.org)
  • Furthermore, the choline in in phosphatidylcholine, which is the major phospholipid in lecithin, is essential for the metabolism of the brain, liver and kidneys. (nutritionaloutlook.com)
  • Phosphatidylcholine is a type of phospholipid that has choline as part of its natural structure. (camformulas.com)
  • The brain is particularly reliant on choline for both structure and function, and this could be one of the reasons why supplementation with Phosphatidylcholine may be beneficial for supporting brain health and for promoting improvements in memory, which in turn can help certain patients suffering from Alzheimer's disease. (camformulas.com)
  • Beef and fish are an excellent source of Phosphatidylcholine, and a 3 oz. serving of beef can provide you with approximately 355 mg of the choline you need to support health. (camformulas.com)
  • Since the daily recommended amount of choline is about 550 mg for adult men and 425 mg for women, a serving of beef could provide you with more than half of your daily requirements of Phosphatidylcholine. (camformulas.com)
  • One large egg can provide you with as much as 126 mg of choline, and an eight ounce glass of milk provides 38 mg of Phosphatidylcholine, on average. (camformulas.com)
  • It is important to realize that studies on Phosphatidylcholine are beneficial where patients have a choline deficiency and not necessarily as a therapy for the disease where this deficiency does not exist. (camformulas.com)
  • Is there a danger in taking lecithin or phosphatidylcholine? (consumerlab.com)
  • These authors explained their results by citing research showing that the enzyme phospholipase A cleaves phosphatidylcholine, or lecithin, into a compound called lysolecithin in the small intestine where it is efficiently absorbed. (westonaprice.org)
  • As with several other poorly absorbed plant-based medicinals such as curcumin, Indena was able to complex the active medicinal silybin with phosphatidylcholine from lecithin for added protection from water and an increased absorption in intestinal cells. (lawsons.ca)
  • Phosphatidylcholine (PC) is a phospholipid that is naturally present in the cell membranes. (herbs2000.com)
  • This versatile phospholipid is recognized for its advantages to liver function as well as a nutrient essential to brain function. (lifestylemarkets.com)
  • One specific phospholipid is called phosphatidylcholine, and it makes up the cell membranes of liver cells. (vin.com)
  • Comparing phospholipid profiles of mitochondria and whole tissue: Higher PUFA content in mitochondria is driven by increased phosphatidylcholine unsaturation. (oregonstate.edu)
  • In an animal model of PFIC3, Abcb4 (Mdr2) knockout mice cannot excrete phospholipid into bile and develop progressive liver disease characterized by portal inflammation, proliferation of bile ducts, and fibrosis. (medscape.com)
  • Especially alcohol is considered to be a poisonous substance for the liver and people who consume extreme amounts of alcohol are susceptible to develop a potentially fatal condition called cirrhosis of the liver . (herbs2000.com)
  • NASH can further develop into cirrhosis of the liver which hardens and scars the liver, inhibiting normal function. (lawsons.ca)
  • Cirrhosis of the Liver Cirrhosis is the widespread distortion of the liver's internal structure that occurs when a large amount of normal liver tissue is permanently replaced with nonfunctioning scar tissue. (msdmanuals.com)
  • stepwise increase in the mean TAG/DAG ratio, FC/PC ratio and hepatic FC from normal livers to NAFL to NASH. (wjgnet.com)
  • Phosphatidylcholine is identified as a membrane lipid, and is a key component of the Essential forte N formula. (bodyroids.com)
  • The goal of this project is to determine why phosphatidylcholine lipid levels are higher in liver cancer and how they might be targeted with drugs to prevent or cure this disease. (damonrunyon.org)
  • Reprogramming of lipid metabolism in hepatocellular carcinoma resulting in downregulation of phosphatidylcholines used as potential markers for diagnosis and prediction. (cdc.gov)
  • TLC spots corresponding to phosphatidylcholine and phosphatidylethanolamine were found in the isooctane extracts. (cdc.gov)
  • Phosphatidylcholine has long been identified as an important supplement for the liver, supporting normal hepatic fat metabolism and overall liver health. (bodyroids.com)
  • The liver and the muscles appear to be the major organs for methyl group metabolism. (nih.gov)
  • Studies that simulated methyl-deficient diets reported disturbances in energy metabolism and protein synthesis in the liver, fatty liver, or muscle disorders. (nih.gov)
  • Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. (westonaprice.org)
  • Another major function of the liver is in regulating the body's metabolism. (lawsons.ca)
  • Silybin complexed with phosphatidylcholine for increased bioavailability. (medicanimal.com)
  • Of the three, it is silybin that is considered the most potent and effective for antioxidant, anti-inflammatory, chemopreventive and liver-protecting benefits. (lawsons.ca)
  • Great potential for liver health exists if the bioavailability issues of silybin could be addressed. (lawsons.ca)
  • When the complex of 33% silybin and 67% phosphatidylcholine was compared against silybin alone, tests showed over a 4-fold increased bioavailability in the blood and a 10-fold increased presence in bile. (lawsons.ca)
  • It has been found that phosphatidylcholine has the ability to strengthen the cell membranes of the liver - the cell's doorkeeper that permits the entry of nourishments into the cells and, at the same time, obstructs the toxins from getting inside the cells. (herbs2000.com)
  • Phosphatidylcholine is made using a process involving SAMe such that the more SAMe is available, the more phosphatidylcholine is produced, and the more fluid the liver cell membranes become, leading to better bile flow. (vin.com)
  • Your body needs an abundance of these healthy fats to be able to produce new cells, since every cell uses Phosphatidylcholine in the structures that form the cell membranes. (camformulas.com)
  • Phosphatidylcholine plays a vital role in supporting the production of new cells and new cell membranes, and is therefore important for supporting the liver. (camformulas.com)
  • Progressive familial intrahepatic cholestasis type 3 (PFIC3) is a rare monogenic disease caused by mutations in the ABCB4 gene, resulting in a reduction in biliary phosphatidylcholine. (unav.edu)
  • Reduced biliary phosphatidylcholine cannot counteract the detergent effects of bile salts, leading to cholestasis, cholangitis, cirrhosis and ultimately liver failure. (unav.edu)
  • Upon sacrifice, markers of PFIC3 disease such as, hepatosplenomegaly, biliary phosphatidylcholine and liver histology were significantly improved. (unav.edu)
  • It conjugates in the liver and is preliminarily defecated by the biliary system (3). (researchsquare.com)
  • It is helpful for people with a history of substance abuse, chronic liver issues from hepatitis and hemolytic anemias. (joyfulbelly.com)
  • Clinical trials have shown that silymarin exerts hepatoprotective effects in acute viral hepatitis, poisoning by A. phalloides , toxic hepatitis produced by psychotropic agents and alcohol-related liver disease, including cirrhosis, at daily doses ranging from 280 to 800mg, equivalent to 400 to 1140mg of standardised extract. (springer.com)
  • Even liver inflammation and contagions like hepatitis may also lead to liver damage and reduce the organ's functioning. (herbs2000.com)
  • In fact, phosphatidylcholine has especially been administered to patients enduring hepatitis B contagion as well as people suffering from liver damage owing to consumption of excessive alcohol. (herbs2000.com)
  • Hepatitis C is a viral disease that can lead to serious and permanent liver damage. (betternutrition.com)
  • Phosphatidylcholine supplements have been found to help protect the liver and have been found to offer benefits in terms of hepatitis and other liver diseases. (camformulas.com)
  • For instance, dietary supplements enclosing this nutritional compound has been found to be useful for people enduring liver disorders, especially those patients who are having liver problems owing to excessive and prolonged use of alcohol and specific medications. (herbs2000.com)
  • A full panel of liver enzymes was used to determine the level of relative hepatic strain. (bodyroids.com)
  • Liver enzymes were also elevated in the steroid users taking Essential forte N, however, they were similar to controls and remained within the normal range.The researchers concluded:"The positive association of the abuse severity with the increased hepatic enzymes' levels suggest a relationship between abused AAS and hepatic cell damage. (bodyroids.com)
  • To study specifically the mechanisms related to Neuhi in AH patients and liver injury, we used the mouse model of chronic-plus-binge ethanol feeding and found that myeloid-specific deletion of the Ncf1 gene abolished ethanol-induced hepatic inflammation and steatosis. (jci.org)
  • moreover, treatment with silymarin was associated with an increase in survival in a placebo-controlled clinical trial in alcoholic liver disease. (springer.com)
  • Pharmacokinetic studies have shown that silymarin is absorbed by the oral route and that it distributes into the alimentary tract (liver, stomach, intestine, pancreas). (springer.com)
  • Effect of silymarin on experimental liver lesions. (springer.com)
  • Silymarin is typically cited as the active component in milk thistle for liver benefits. (lawsons.ca)
  • Methyl groups are important for numerous cellular functions such as DNA methylation, phosphatidylcholine synthesis, and protein synthesis. (nih.gov)
  • SAMe enhances liver synthesis of glutathione, an antioxidant. (a1supplements.com)
  • In fact, Phosphatidylcholine is found in the highest concentrations in the brain and the liver, where it is essential for supporting these organs. (camformulas.com)
  • As mentioned, the brain and liver contain the highest concentrations of Phosphatidylcholine, and they are dependent on Phosphatidylcholine for supporting their functions. (camformulas.com)
  • Scrapes fats / cleanses blood vessels by 1) purging bile, 2) strengthening the liver's ability to metabolize fats, 3) by increasing uptake of cholesterol in the liver, and 4) by inhibiting fat cells. (joyfulbelly.com)
  • Apart from alcohol, medications prescribed by doctors regularly, such as medicines for lowering cholesterol levels, chemotherapy as well as psychotropic drugs (drugs that are able to affect the mind) are likely to harm the liver if used for a prolonged period of time. (herbs2000.com)
  • In fact, phosphatidylcholine helps in making cholesterol additionally solvable and thereby prevents the arteries from becoming harder. (herbs2000.com)
  • Not surprisingly, the regenerative powers of the liver are unique among all internal organs and PC empowers the liver to rebuild and regenerate its hard-working tissues. (procapslabs.com)
  • Maintaining the good health of the liver is vital for our very existence, since this is one of the most crucial organs of the body. (herbs2000.com)
  • The liver is exposed to a variety of toxins and pathogens, and it is one of the organs of the body which has the ability to regenerate cells that may be damaged due to toxin exposure. (camformulas.com)
  • The liver is one of the most important organs in the body. (lawsons.ca)
  • In Canada, milk thistle has become the most commonly used natural product for liver issues. (lawsons.ca)
  • Dietary enhancements containing phosphatidylcholine or PC are utilized for various remedial causes. (herbs2000.com)
  • Are we to eat liver and egg yolks to support our liver health and mental health only to wind up with heart disease as a result? (westonaprice.org)
  • According to scientists, this advantage of phosphatidylcholine is primarily owing to the fact that it contains high levels of linoleic acid , which is considered to be an indispensable and healthy fat. (herbs2000.com)
  • Due to the fact that Phosphatidylcholine plays such an important role in supporting cellular membrane formation and in producing healthy nerve cells, there have been numerous studies that have focused on Phosphatidylcholine supplementation and its effects on brain health. (camformulas.com)
  • A healthy diet and a patented natural ingredient are two ways to help protect the liver and keep it functioning effectively for years to come. (lawsons.ca)
  • When one is unable to protect the liver through a healthy lifestyle or has already sustained liver damage, extra support may be needed to boost the liver's performance. (lawsons.ca)
  • While PC cannot be called a panacea, as it is not able to cure all liver aliments, in many patients, the substance aids in speedy recovery from any liver disease . (herbs2000.com)
  • The cycle of disease from infection to significant liver damage can take 20 years or more", writes C. Everett Koop, former Surgeon General of the United States and now director of the C. Everett Koop Institute at Dartmouth. (betternutrition.com)
  • In veterinary medicine, this product is chiefly used in liver disease, in senility/cognitive dysfunction, and in detoxification in several types of poisonings (such as toxicity of acetaminophen, xylitol, and amanita mushroom). (vin.com)
  • Although Phosphatidylcholine is not a cure for the disease, studies show that supplementation with Phosphatidylcholine may offer some support for Alzheimer's patients and may offer other health benefits, too. (camformulas.com)
  • They are using zebrafish, which form tumors similar to the human disease and can be easily manipulated to study liver cancer. (damonrunyon.org)
  • Functional loss of this gene results in cholestatic liver disease. (medscape.com)
  • Alcohol-related liver disease is liver damage caused by drinking too much alcohol for a long time. (msdmanuals.com)
  • If people who have been drinking in excess have symptoms of liver disease, doctors do blood tests to evaluate the liver and occasionally do a liver biopsy. (msdmanuals.com)
  • As far as the health of the liver is concerned, the same can be said about the apparently harmless non-prescription medicines like aspirin and acetaminophen . (herbs2000.com)
  • Phosphatidylcholine is a non-prescription substance, but if any individual has a current ailment or a history of liver disorders, he or she needs to undergo treatment under the supervision of a qualified and competent doctor or healthcare provider who is able to help them to work out a program to improve the health of the liver. (herbs2000.com)
  • Supports Liver Health & Detoxification. (a1supplements.com)
  • This nutritional health supplement protects and supports liver cells from damage from free radicals. (blueskyvitamin.com)
  • Strong trend for high nutritious food consumption owing to rise in health concerns among consumers should drive egg phosphatidylcholine market size. (gminsights.com)
  • Studies involving the supplementation with Phosphatidylcholine have found that Phosphatidylcholine offers numerous health benefits. (camformulas.com)
  • Most people might assume that alcohol consumption would be the primary health issue related to the liver. (lawsons.ca)
  • Glutathione promotes detoxification and liver protection. (a1supplements.com)
  • further, it has been shown that most canine and feline liver patients are deficient in glutathione. (vin.com)
  • I am now in my mid 50s and although I tried to take care of myself, my liver enzyme levels were moving steadily up. (procapslabs.com)
  • When I went to my doctor this week, she said my liver enzyme levels were completely normal. (procapslabs.com)
  • Excellent liver enzyme test Since I was 15 years old I have always had a bilirubin test result that was above the range of normal. (procapslabs.com)
  • Cholagogues stimulate the production & release of bile from the liver & gallbladder. (joyfulbelly.com)
  • Immunohistochemistry-Paraffin: SR-BI Antibody [NB400-104] - FFPE tissue section of mouse liver using SR-BI antibody (Lot 8310) at 1:300 dilution with HRP-DAB detection and hematoxylin counterstaining. (novusbio.com)
  • Studies show SAMe may protect liver tissue from injury caused by a number of toxins. (a1supplements.com)
  • Fibrosis of the Liver Fibrosis is the formation of an abnormally large amount of scar tissue in the liver. (msdmanuals.com)
  • Effects of Extraction with Isooctane upon the Properties of Liver Microsomes. (cdc.gov)
  • The effects of extraction with isooctane (540841) on substrate hemoprotein spectrophotometric binding properties of liver microsomes were studied in-vitro. (cdc.gov)
  • Liver microsomes obtained from male Holtzman-rats, pretreated with 50mg/kg sodium-phenobarbital daily for 3 days were used. (cdc.gov)
  • The authors conclude that after isooctane extraction rat liver microsomes cannot bind hexobarbital and produce a type-I difference spectrum. (cdc.gov)
  • Isooctane apparently destroys or modifies the normal hexobarbital binding form of cytochrome-P450 in liver microsomes. (cdc.gov)
  • For instance, exposure to drugs over a prolonged period of time, contaminants as well as drinking too much of alcohol is likely to harm the liver. (herbs2000.com)
  • Pesticides, preservatives, alcohol and metabolic waste are diluted by less toxic substances in the liver to prepare them for safe excretion by the kidneys and bowel. (lawsons.ca)
  • Cirrhosis is also commonly associated with liver damage from alcohol consumption and can lead to morbidity. (lawsons.ca)
  • Drugs, alcohol and caffeine put additional strain on the liver. (lawsons.ca)
  • In general, the amount of alcohol consumed (how much, how often, and for how long) determines the risk and severity of liver damage. (msdmanuals.com)
  • Most alcohol, after being absorbed in the digestive tract, is processed (metabolized) in the liver. (msdmanuals.com)
  • As alcohol is processed, substances that can damage the liver are produced. (msdmanuals.com)
  • The more alcohol a person drinks, the greater the damage to the liver. (msdmanuals.com)
  • When alcohol damages the liver, the liver can continue to function for a while because the liver can sometimes recover from mild damage. (msdmanuals.com)
  • However, if people continue to drink alcohol, liver damage progresses and may eventually result in death. (msdmanuals.com)
  • SAMe may also upregulate the production of phosphatidylcholine, supporting cognitive function. (a1supplements.com)
  • They also showed that feeding mice phosphatidylcholine did in fact produce TMAO, but only in the presence of gut bacteria. (westonaprice.org)
  • Blocking PD-1 or HMGB1 unleashes T cell activation and prolongs survival of mice with Gpx4 -deficient liver tumours. (bmj.com)
  • A triple combination of the ferroptosis inducing natural compound withaferin A, the CXCR2 inhibitor SB225002 and α-PD-1 greatly improves survival of wild-type mice with liver tumours. (bmj.com)
  • NAFLD is the accumulation of fat in the liver, which can lead to chronic inflammation of the liver and eventually liver damage. (lawsons.ca)
  • NAFLD is diagnosed by blood testing that evaluates liver functions. (lawsons.ca)
  • Symptoms range from none at first to fever, jaundice, fatigue, and a tender, painful, and enlarged liver, then to more serious problems such as bleeding in the digestive tract and deterioration of brain function. (msdmanuals.com)
  • Also, socio-religion concerns for other nutritive sources including beef and pork may increase the egg phosphatidylcholine industry demand. (gminsights.com)
  • Objective : Silibinin is an antioxidant agent and is shown to have anticancer effects in different cancers including lung, breast, colorectal, liver, prostate, and kidney. (researchsquare.com)
  • This study investigated differences in lipidomic profile features in nonalcoholic steatohepatitis (NASH) between mild and significant liver fibrosis cases among patients with morbid obesity. (bvsalud.org)
  • Wedge liver biopsy was performed during sleeve gastrectomy and significant liver fibrosis was defined as a fibrosis score ≥ 2. (bvsalud.org)
  • Since liver cells are directly involved in detoxification of the body, they are especially at risk for accumulating harmful biochemicals. (vin.com)
  • Several clinical studies have noted that phosphatidylcholine or PC has the aptitude to arrest the damage of the liver. (herbs2000.com)
  • Essentiale forte N is the trade name for a liver-support supplement distributed in Europe by Aventis Pharma. (bodyroids.com)
  • While this one study does not assure that steroid liver toxicity can be completely eliminated, it does lend strong support for the use of Essential forte N with hepatotoxic anabolic steroids. (bodyroids.com)
  • Liver Support for Dogs: Denamarin is the #1 veterinarian recommended liver support supplement for dogs. (petcarerx.com)
  • Liver Support by Vital Nutrients is a high quality blend of herbal extracts which are designed to help with supporting optimal liver functions. (blueskyvitamin.com)
  • Antioxidants are an important treatment in preserving mental acuity in old age, and Novifit is primarily marketed for this purpose, while Denosyl and Denamarin are mostly marketed for liver support. (vin.com)
  • Then our livers detoxify the trimethylamine to an odorless product called trimethylamine oxide (TMAO). (westonaprice.org)
  • While this prevents us from walking around smelling like we've been swimming in a barrel full of fermenting cod livers, the authors argue that TMAO fills our arteries with plaque. (westonaprice.org)
  • In PFIC3, a mutation in the gene ABCB4 on chromosome 7q21 encodes the protein MDR3, which functions in the translocation of phosphatidylcholine across the canalicular membrane. (medscape.com)
  • On the other hand, the liver is an exceedingly laborious organ that purifies the blood by eliminating harmful and hazardous toxins absorbed by the body from ingested food, owing to pollution as well as exposure to chemical substances. (herbs2000.com)
  • Phosphatidylcholine has been found beneficial for patients with bipolar disorder, Huntington's chorea, and Tourette's syndrome. (camformulas.com)
  • Drs. Evason and Ducker found that a certain type of fat (phosphatidylcholine lipids) is elevated in both zebrafish and human liver cancer cells. (damonrunyon.org)
  • Essential forte N is of interest to steroid using bodybuilders and athletes for its ability to reduce the level of liver strain caused by anabolic/androgenic steroids (particularly those compounds that are c-17 alpha alkylated). (bodyroids.com)
  • These compounds included 2 sphingomyelins, 1 phosphatidylcholine, 1 sphinganine-phosphate, and 1 ceramide, a finding that further supports the role of ceramides in human pancreatic cancer, the researchers say. (medscape.com)