Mechanistic toxicology is the study of how chemical or physical agents interact with living organisms to cause toxicity. (cloudaccess.net)
Thyroid3
1999 . Species Differences in Thyroid, Kidney and Urinary Bladder Carcinogenesis. (nih.gov)
Wistar rats receiving a single injection of 2,2′-dihydroxy-N-nitrosodipropylamine (a tumor initiator) followed by 4,4′-methylenedianiline (MDA) in the diet for 19 weeks, developed thyroid follicular cell carcinomas and follicular cell and papillary adenomas. (cdc.gov)
Fischer 344/N rats and B6C3F l mice receiving MDA as 4,4′-methylenedianiline dihydrochloride ad libitum in drinking water for 2 years developed thyroid follicular cell carcinomas and adenomas, C-cell adenomas of the thyroid, hepatocellular carcinomas and adenomas, alveolar bronchiolar adenomas, malignant lymphomas, and benign tumors of the adrenal gland. (cdc.gov)
Microsomal3
1981 . The selective activation of cytochrome P-450 dependent microsomal hydroxylases in human and rat liver microsomes. (nih.gov)
Stability of the microsomal monooxygenases during incubations for the liver microsomal assay with S-9 fractions of mouse liver under various inductions. (unibo.it)
Microsomal electron transport chain: monooxygenase activities and relationships between NADPH-cytochrome c-reductase and cytochrome P450 in mouse liver. (unibo.it)
Assay1
2001. Evaluation of benzene exposure in children living in Campania (Italy) by urinary trans,trans -muconic acid assay. (cdc.gov)
Trans1
Comparative genetic activity of cis- and trans- 1,2-dichloroethylene in yeast. (unibo.it)