• hypercholesterolemia
  • It is used in diseases featuring high LDL, such as the rare homozygous familial hypercholesterolemia, when the heterozygous form does not respond to medical treatment, or when the treatment has led to dangerous side-effects (such as rhabdomyolysis). (wikipedia.org)
  • An example of the application of the nutrigenomic approach was a study that simultaneously identified a mechanism for the regulation of sterol uptake in the intestine and the basis for sitosterolemia (a genetic disorder characterized by hyperabsorption of dietary sterols leading to hypercholesterolemia with a high risk of developing atherosclerosis). (wikipedia.org)
  • coronary
  • The first aim of this study is to develop and optimize clinical imaging protocols and techniques for fast high-resolution coronary MRA and wall imaging for the assessment of coronary and other main arteries structural, distensibility, and endothelial functional parameters. (clinicaltrials.gov)
  • Results from accelerated high-resolution MRA will be correlated with corresponding Computerized Tomography Coronary Angiogram (CTA) results. (clinicaltrials.gov)
  • hepatic
  • citation needed] Gemfibrozil should not be given to these patients:[citation needed]Hepatic dysfunction Gemfibrozil should be used with caution in these higher risk categories:[citation needed]Biliary tract disease Renal dysfunction Pregnant women Obese patients Anticoagulants: Gemfibrozil potentiates the action of warfarin and indanedione anticoagulants. (wikipedia.org)
  • activator
  • The structure of lipoprotein(a) is similar to plasminogen and tPA (tissue plasminogen activator) and it competes with plasminogen for its binding site, leading to reduced fibrinolysis. (wikipedia.org)
  • hyperlipidemic
  • 24 hyperlipidemic females followed diet low in saturated fat for a month, then they were randomly placed into a dietary portfolio low or high in monounsaturated fatty for another month. (wikipedia.org)
  • molecules
  • Since lipids are insoluble in blood (plasma), they must be transported to and from the cells by special carrier molecules, the lipoproteins. (sabinsa.com)
  • Stroke
  • Mitral stenosis poses a high risk of forming emboli which may travel to the brain and cause stroke. (wikipedia.org)
  • ACCELERATE studied evacetrapib in participants with high-risk vascular disease (previous myocardial infarction, stroke or peripheral vascular disease, or several cardiovascular risk factors). (wikipedia.org)
  • patients
  • In recent years, aerobic exercises, such as Chinese traditional exercise Baduanjin and Tai Ji, jogging, and yoga, are reported to be generally beneficial to healthy adults or the hyperlipidemia patients. (hindawi.com)
  • concentrations
  • The mean and median concentrations between different world populations show distinct particularities, the main being the two- to threefold higher Lp(a) plasma concentration of populations of African descent compared to Asian, Oceanic, or European populations. (wikipedia.org)
  • subsequently
  • Beta cells in the pancreas subsequently increase their production of insulin, further contributing to a high blood insulin level. (wikipedia.org)
  • reduce
  • The study found that the effective management of hyperlipidemia could obviously reduce cardiovascular morbidity and mortality substantially [ 5 ]. (hindawi.com)
  • It concluded that using dietary portfolio high in monounsaturated fatty acid is able to further reduce cardiovascular risk by increasing. (wikipedia.org)
  • plasma
  • Lipoprotein(a) is not fully synthesized until the precursor protein is released from the cell, so the slower rate of production for the larger isoforms limits the plasma concentration. (wikipedia.org)
  • risk
  • It has been recognized for over one-half century that significant LMCA disease is associated with a poor prognosis, with 3-year mortality rates in the pre-revascularization era as high as 63% in high-risk subgroups (1) . (onlinejacc.org)
  • For treatment of hyperlipidemia, statins and fibrates are highly effective, but may cause a markedly increased risk of myopathy and rhabdomyolysis [ 7 ]. (hindawi.com)
  • Posted June 4, 2016 By Alan Mozes HealthDay Reporter TUESDAY, May 31, 2016 (HealthDay News) -- More evidence links air pollution with increased risk of developing dangerous high blood pressure. (livingnaturally.com)
  • Posted February 17, 2016 MONDAY, Feb. 15, 2016 (HealthDay News) -- Having a physically demanding job and high blood pressure may triple a woman's risk of heart disease, a new study contends. (livingnaturally.com)
  • Posted October 3, 2014 By Steven Reinberg HealthDay Reporter WEDNESDAY, Oct. 1, 2014 (HealthDay News) -- Living close to a major highway may raise your risk for high blood pressure, a new study suggests. (livingnaturally.com)
  • Other efforts include managing high blood pressure, high blood cholesterol, and infection risk. (wikipedia.org)
  • Evacetrapib evaluation for treatment of high-risk vascular disease was discontinued due to lack of efficacy, as had already happened in the past with two other CETP inhibitors (torcetrapib and dalcetrapib) due to increased deaths and little identifiable cardiovascular benefit (despite substantial increases in HDL). (wikipedia.org)
  • insulin
  • When the body produces insulin under conditions of insulin resistance, the cells are resistant to the insulin and are unable to use it as effectively, leading to high blood sugar. (wikipedia.org)