• tissue
  • Intestinal tissue samples were examined under light microscope. (hindawi.com)
  • In the present study, IR model caused an increase in intestinal injury.In the present study, ozone administration had an effect improving IR associated tissue injury. (hindawi.com)
  • The protective function is not restricted to the intestinal tissue but extends to all tissues because of its transport from the intestinal mucosa to the circulation ( 13 , 15 ). (physiology.org)
  • Mean porfimer sodium tissue content of 3.9 mg/kg (range, 2.1-8.1 mg/kg) and mean total light dose of 268 J/cm (range, 250-350 J/cm) resulted in an incomplete treatment. (aacrjournals.org)
  • Whereas previous PDT dosimetry studies have focused on PDT light dose, our project studied factors related to optimal treatment outcomes, including the porfimer sodium tissue content, photodynamic dose, and the distal esophageal wall thickness. (aacrjournals.org)
  • The mechanism of PDT ablation involves light activation of the photosensitizer, which then reacts with molecular oxygen to generate reactive oxygen species and trigger apoptosis, activation of the host immune system, and vascular damage resulting in tissue necrosis ( 4 ). (aacrjournals.org)
  • PDT using porfimer sodium activated by 630-nm red light allows deep tissue penetration of light energy to drive the photodynamic reaction with little risk of perforation because there is no damage to the collagen gut wall infrastructure ( 5 ). (aacrjournals.org)
  • Barrett's esophagus involves change in the mucosa of the esophagus into a tissue that includes glands (intestinal metaplasia), and as a result, can be identified with methylene blue staining. (wikipedia.org)
  • The mucosa is washed and the dye is applied to tissue while the endoscope is retracted by 20 to 30 centimetres. (wikipedia.org)
  • Various classification of "pit patterns" in the mucosa have been used to attempt to correlate to tissue type. (wikipedia.org)
  • There are six distinctive morphological patterns of necrosis: Coagulative necrosis is characterized by the formation of a gelatinous (gel-like) substance in dead tissues in which the architecture of the tissue is maintained, and can be observed by light microscopy. (wikipedia.org)
  • esophageal
  • The enhanced photodynamic dose was determined as [porfimer sodium content * light dose/esophageal thickness]. (aacrjournals.org)
  • Porfimer sodium photodynamic therapy (PDT) is approved for the treatment of patients with esophageal carcinoma and Barrett's high-grade dysplasia (HGD), although its dosimetry is poorly understood, resulting in variable treatment results for patients who receive the same drug and light dose. (aacrjournals.org)
  • squamous
  • Depending on the reason for which chromoendoscopy is being performed, the dye can be sprayed directly on a suspected abnormality (such as for identification of squamous cell carcinoma) or diffusely to the mucosa (such as for screening for dysplasia in ulcerative colitis When the stain is applied diffusely in the colon, a complete colonoscopy is performed with the instrument lying in the cecum. (wikipedia.org)
  • infection
  • However, the symptoms of immune deficiency characteristic of AIDS do not appear for years after a person is infected, the bulk of CD4+ T cell loss occurs during the first weeks of infection, especially in the intestinal mucosa, which harbors the majority of the lymphocytes found in the body. (wikipedia.org)
  • fatty
  • Two fatty acid binding protein genes designated liver fatty acid binding protein ( Fabpl ) and intestinal fatty acid binding protein ( Fabpi ), as well as the sucrase-isomaltase gene ( Si ), have been especially well studied using transgenic systems ( 9 , 28 , 29 , 34 , 38 ). (physiology.org)
  • parasite
  • The failure to identify the parasite determinants responsible for the production of intestinal injury, diarrhoea, and malabsorption makes it impossible to provide a simple explanation for the molecular pathogenesis of giardiasis (4) . (lww.com)
  • It is an intestinal parasite in humans causing taeniasis (a type of helminthiasis) and cysticercosis in cattle. (wikipedia.org)
  • colon
  • Dietary omega-3 intake from fish meat or fish oil may reduce intestinal disorders and be an effective adjuvant in colon cancer therapy 5 . (scielo.br)
  • That area of mucosa is characterized, and then the procedure is repeated in the next area of the colon that is more distal, until the procedure is completed. (wikipedia.org)
  • lymphocytes
  • The TNF superfamily member homologous to lymphotoxins, exhibits inducible expression, and competes with HSV glycoprotein D for herpesvirus entry mediator (HVEM), a receptor expressed by T lymphocytes (LIGHT) [TNF superfamily (SF)- is a key cytokine that activates T cells and dendritic cells and is implicated as a mediator of inflammatory, metabolic, and malignant diseases. (jimmunol.org)
  • Homologous to lymphotoxins, exhibits inducible expression, and competes with HSV glycoprotein D for herpesvirus entry mediator (HVEM), a receptor expressed by T lymphocytes (LIGHT), a member of the TNF superfamily (SF) of cytokines (TNFSF14), acts as a cosignaling system for T lymphocytes ( 5 , 6 ). (jimmunol.org)
  • Inflammation
  • Attachment and effacement causes the diarrhea, while the Shiga toxin produces capillary thrombosis and inflammation of the colonic mucosa, leading to hemorrhagic colitis. (garlandscience.com)
  • However, colitis-associated neoplastic lesions in patients with IBD are extremely difficult to find because they tend to be flat and indistinguishable against the background mucosa due to the surrounding chronic inflammation [ 10 , 11 ]. (e-ce.org)
  • Barrett's
  • Endoscopic image of gastric antral vascular ectasia seen as a radial pattern around the pylorus before (top) and after (bottom) treatment with argon plasma coagulation Endoscopic image of Barrett's esophagus, which is the area of red mucosa projecting like a tongue. (wikipedia.org)
  • Crystal violet is absorbed into intestinal and neoplastic cells and is used to identify Barrett's esophagus and colonic neoplasms. (wikipedia.org)
  • absorption
  • Small intestinal histology, radiology and absorption. (springer.com)
  • Intestinal villi are considered the functional units of the digestive system because absorption through these structures is how digested molecules enter the blood or lymph purchase 20 gr benzac free shipping acne meds. (pili.org)
  • vitamin
  • Vitamin A is needed by the retina of the eye in the form of retinal, which combines with protein opsin to form rhodopsin, the light-absorbing molecule necessary for both low-light (scotopic vision) and color vision. (wikipedia.org)
  • Due to the unique function of retinal as a visual chromophore, one of the earliest and specific manifestations of vitamin A deficiency is impaired vision, particularly in reduced light - night blindness. (wikipedia.org)
  • receptor
  • A neutralizing Ab failed to bind the LIGHT-214K variant, indicating this position as a part of the receptor-binding region. (jimmunol.org)
  • LIGHT activates two cellular receptors, the HVEM (TNFRSF14) and the lymphotoxin-β receptor (LTβR) ( 7 ). (jimmunol.org)
  • LIGHT also engages decoy receptor-3 (DcR3), a soluble TNFSF receptor lacking transmembrane and signaling domains that probably acts to limit bioavailability of LIGHT ( 9 , 10 ). (jimmunol.org)
  • In 30 cases of IBS (PI-IBS, n = 15) taken at random from the 56 cases, expression of interleukin (IL)-1α, IL-1β, and IL-1 receptor antagonist (IL-1ra) mRNAs in intestinal mucosa were identified using reverse transcription-polymerase chain reaction. (bmj.com)
  • mechanism
  • The increased potential for LTβR signaling, coupled with increased bioavailability due to lower DcR3 avidity, provides a mechanism of how polymorphic variants in LIGHT could contribute to the pathogenesis of inflammatory diseases. (jimmunol.org)
  • The underlying mechanism may be associated with the intestinal oxidative stress injury. (hindawi.com)
  • digestive
  • A specialized portion of the mesentery, the mesocolon, churn the chyme with digestive juices and bring it into contact supports the transverse portion of the large intestine along the with the mucosa. (pili.org)
  • Small
  • These results indicate that the MUC2 5′-flanking sequence contains elements sufficient for the appropriate expression of MUC2 in small intestinal goblet cells. (physiology.org)
  • These structures are called the intestinal crypts (crypts of Lieberkühn) (see fig. Mechanical Activities of the Small Intestine Contractions of the longitudinal and circular muscles of the small intestine produce three distinct types of movement: rhyth- mic segmentation, pendular movements, and peristalsis. (pili.org)
  • cells
  • the mammalian intestinal mucosa undergoes constant and rapid renewal throughout life and provides an excellent opportunity for the study of gene expression and differentiation in highly specialized cells ( 8 ). (physiology.org)
  • normal
  • The intestinal mucosa was essentially normal in all seven cases including those with biochemical evidence of malabsorption. (springer.com)
  • Left column: Normal light. (wikipedia.org)
  • New Eng J Med 1973:289;934-937) Light smokers with the susceptible genotype CYP1A1 have a sevenfold higher risk of developing lung cancer compared to light smokers with the normal genotype. (wikipedia.org)
  • function
  • and the xanthophyll beta-cryptoxanthin (all of which contain beta-ionone rings), but no other carotenoids, function as provitamin A in herbivores and omnivore animals, which possess the enzyme beta-carotene 15,15'-dioxygenase which cleaves beta-carotene in the intestinal mucosa and converts it to retinol. (wikipedia.org)
  • study
  • The purpose of this study was to evaluate the anticancer potential of dietary omega-3 supplementation to reduce induced intestinal preneoplastic lesions in Wistar rats. (scielo.br)
  • loss
  • In young children and previously unexposed adults, particularly travelers from low- to high-prevalence parts of the world, Giardia can produce serious diarrhoeal illness with intestinal malabsorption, marked weight loss, and in infants and young children, impairment of growth and development. (lww.com)
  • range
  • Mean porfimer sodium content of 6.2 mg/kg (range, 2.6-11.2 mg/kg) and mean total light dose of 278 J/cm (range, 225-360 J/cm) resulted in a complete treatment. (aacrjournals.org)
  • effect
  • Heterotrimers of the LIGHT variants decreased binding avidity to DcR3 and minimized the inhibitory effect of DcR3 toward LTβR-induced activation of NF-κB. (jimmunol.org)
  • present
  • citation needed] Carotenemia is more easily appreciated in light-complexioned people, and it may present chiefly as an orange discolouration of the palms and the soles in more darkly pigmented persons. (wikipedia.org)