• In contrast, higher postnatal exposure to ozone was linked to a 3.3 percent higher risk of failing most domains of the developmental screen at 8 months, a 17.7 percent higher risk of overall screening failure at 24 months, and a 7.6 percent higher risk of overall screening failure at 30 months. (nih.gov)
  • During prenatal and postnatal time periods, epigenetic processes fine-tune neurodevelopment towards an end product that determines how an organism interacts with and responds to exposures and experiences throughout life. (nih.gov)
  • Scholars@Duke publication: Fetal terbutaline exposure causes selective postnatal increases in cerebellar alpha-adrenergic receptor binding. (duke.edu)
  • Prenatal and postnatal environment exposures may disturb lung growth and delay immune system maturation, resulting in an increased susceptibility to asthma and wheezing disorders in childhood. (bvsalud.org)
  • OBJECTIVE: To evaluate the neuropsychomotor development (NPMD) of children exposed to congenital Zika virus infection and its association with prenatal, neonatal, and postnatal characteristics and diagnoses of the mother/child. (bvsalud.org)
  • This malathion dose regimen caused no significant AChE inhibition in the brain or blood of dams and offspring and had no significant effect on the postnatal growth of the offspring. (nih.gov)
  • In dermal Segment I and III studies with Gelec (Ammonium Chloride) lactate formulations there were no effects observed in fertility or pre- or postnatal development parameters in rats at dose levels of 300 mg/kg/day (1800 mg/m 2 /day), approximately 0.4 times the human topical dose. (sdrugs.com)
  • Two major types of NAS are recognized: NAS due to prenatal or maternal use of substances that result in withdrawal symptoms in the newborn and postnatal NAS secondary to discontinuation of medications such as fentanyl or morphine used for pain therapy in the newborn. (medscape.com)
  • Postnatal neonatal abstinence syndrome results when an abrupt discontinuation of opioid analgesia occurs, usually after prolonged drug exposure. (medscape.com)
  • [ 1 , 2 ] This article focuses on prenatal or maternal use of illicit drugs, although symptoms and therapy for postnatal neonatal abstinence syndrome are similar. (medscape.com)
  • The effect of prenatal and postnatal environmental tobacco smoke exposure on infant health. (precisionenvironmed.com)
  • These may include genetic factors, infections, traumatic or toxic exposure or nutritional factors which result in perinatal or postnatal damage. (who.int)
  • Because a sizable population of young, married women were supplied with this water in their homes, concern has been raised about the potential adverse effects of VOCs on pregnancy outcomes. (cdc.gov)
  • Moreover, children born to women exposed during pregnancy to higher-than-normal levels of traffic-related pollutants-ultra-fine airborne particles and ozone-had a small but significantly higher likelihood of developmental delays during infancy and early childhood. (nih.gov)
  • Our results suggest that it may be prudent to minimize exposure to air pollution during pregnancy, infancy, and early childhood-all key periods for brain development," said Pauline Mendola, Ph.D., an investigator in the Division of Intramural Population Health Research at NIH's Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and the study's senior author. (nih.gov)
  • Previous studies have linked exposure to common air pollutants in pregnancy to low birthweight, preterm birth and stillbirth. (nih.gov)
  • The association between exposure to secondhand smoke (SHS) during pregnancy and a child's neurodevelopment has not been established yet. (biomedcentral.com)
  • We quantified urine cotinine concentrations in mothers once from 12th to 20th gestational weeks and excluded those whose urine cotinine levels exceeded 42.7 ng/ml to represent SHS exposure in early pregnancy. (biomedcentral.com)
  • Maternal exposure to SHS during pregnancy may result in delayed MDI in early childhood. (biomedcentral.com)
  • Metabolic gene polymorphisms might modify the effect of toxins on the outcome of pregnancy and development afterwards. (biomedcentral.com)
  • Average exposure levels to PM 10 and NO 2 during the entire pregnancy were estimated using the inverse distance weighting (IDW) method. (ewha.ac.kr)
  • The study is enrolling those with and without exposure to Benlysta®, and will provide critical information on the use of this medication during pregnancy. (betterbeginnings.org)
  • The Organization of Teratology Information Specialists (OTIS) is a professional scientific society made up of individuals engaged in assessing and evaluating risks to pregnancy and breastfeeding from environmental exposures. (betterbeginnings.org)
  • The clearest example of a disruptor is diethylstilbestrol (DES), a chemical that behaves like a hormone and not only affects the health of the exposed person, but also can generate irreversible damage to their descendants since the exposure of a mother to these compounds during pregnancy can generate varied and unexpected effects on the offspring several decades after having been exposed in utero. (ivis.org)
  • Associations between infant developmental delays and secondhand smoke exposure modified by maternal pre-pregnancy overweight and obesity status. (precisionenvironmed.com)
  • We conclude that fetal and neonatal exposure to nicotine caused blood pressure elevation. (mcmaster.ca)
  • Primary treatment of neonatal symptoms related to prenatal substance exposure should be supportive because pharmacologic therapy can prolong hospitalization and exposes the infant to additional agents that are often not necessary. (medscape.com)
  • Maternal substance abuse, the cause of prenatal neonatal abstinence syndrome, is a leading preventable cause of mental, physical, and psychological problems in infants and children. (medscape.com)
  • Disability may be developmental or acquired and may arise from prenatal damage, perinatal factors, acquired neonatal factors and early childhood factors. (who.int)
  • Despite this, the incidence of leukemia during the prenatal and neonatal stages is very low (~1% of all childhood leukemia cases), and leukemia usually develops at a later stage after birth. (lu.se)
  • We explored the association between prenatal exposure to SHS and neurodevelopment at 24 months of age considering genetic polymorphism and breastfeeding in 720 mothers and their offspring enrolled in the Korean multicenter birth cohort study (Mothers and Children Environmental Health, MOCEH). (biomedcentral.com)
  • Objectives: We aimed to investigate the association between prenatal exposure to particulates of less than 10μm in diameter (PM 10 ) and nitrogen dioxide (NO 2 ) and neurodevelopment in children during the first 24months of their lives. (ewha.ac.kr)
  • Male gender, high birthweight, exposure to in utero maternal smoking and current exposure to household environmental tobacco smoke (stronger effect of maternal than paternal smoking) were positively associated with childhood overweight/obesity. (nih.gov)
  • Epigenetic marks generated within germ cells as a result of environmental influences throughout life can also shape future generations long before conception occurs. (nih.gov)
  • World Health Organization (WHO) has recently reported that environmental risks including SHS take lives of 1.7 million children under 5 years of age every year [ 2 ]. (biomedcentral.com)
  • Harmful exposure to these environmental risks could begin in the mother's womb and affect fetal development. (biomedcentral.com)
  • Placental passage of these environmental toxicants might affect prenatal nervous system development. (biomedcentral.com)
  • Asthma prevalence has been increasing worldwide, not only due to the genetic background, but also mainly because of the effect of environmental risk factors. (bvsalud.org)
  • The combined effects of genotypes and environmental factors together on phenotypic characteristics. (lookformedical.com)
  • Data from mother-child pairs in the Swedish Environmental Longitudinal, Mother and child, Asthma and allergy (SELMA) study was analyzed, including 26 EDCs in prenatal urine and serum samples, children's anthropometric and body composition measures up to seven years of age, and sociodemographic data from questionnaires and registers. (diva-portal.org)
  • Early life is an important period for growth and development and therefore, sensitive to environmental exposures, such as chemicals and nutrition. (diva-portal.org)
  • But we need more knowledge on how these environmental exposures may influence children's growth and if there are sex specific effects. (diva-portal.org)
  • investigators planning research in this area must look to other studies of the impact of chronic environmental trauma on children, including the effects of war and child maltreatment. (ubbcluj.ro)
  • NIEHS research uses state-of-the-art science and technology to investigate the interplay between environmental exposures, human biology, genetics, and common diseases to help prevent disease and improve human health. (nih.gov)
  • Furthermore, birth season which is frequently applied as a proxy for environmental exposure in early life may influence the health outcome in the later life. (biomedcentral.com)
  • Environmental risk - maternal and family care, health care, nutrition, and limited opportunities for stimulation of normal development leading to delays in development. (familydoctor.co.nz)
  • Francheska M. Merced-Nieves, PhD, Assistant professor, Departments of Pediatrics and the Institute for Exposomic Research of Environmental Medicine & Public Health, Icahn School of Medicine at Mount Sinai, explains the associations prenatal exposure to a metal mixture and the potential negative effects for the infant. (contemporarypediatrics.com)
  • There is a great need to better understand the impact of traumatic events very early in life on the course of children's future development. (ubbcluj.ro)
  • It looks at delays in children's development, the risk factors for delays, and what tests are used to assess a child's progress. (familydoctor.co.nz)
  • RESULTS: Exposure to the farm ing environment in utero and in early childhood had little or no association with asthma but was associated with reduced odds of atopy. (cdc.gov)
  • Fetal development can be disrupted by toxic chemical exposures in less time than the 6-month intervals at which the wells are being monitored. (cdc.gov)
  • No unusual toxic effects were reported. (sdrugs.com)
  • A contaminant will produce adverse or toxic effects only if it (or its metabolites) reaches specific sites in the body at a dose and over a duration sufficient to produce an adverse non-cancer effect. (cdc.gov)
  • The toxic effect of a contaminant will be influenced by its toxicokinetic or pharmacokinetic properties (e.g., rates of absorption, distribution, metabolism, and elimination ). (cdc.gov)
  • One of the most significant examples of synthetic estrogens having possible toxic effect was exhibited through the use of diethylstilboestrol or DES. (benjaminbarber.org)
  • The earlier in life that toxic exposure occurs, the more powerful the toxins affect a child's development ongoing from that day forward. (susansmithjones.com)
  • The toxic effects of such chemicals in the developing human brain are not known and they are not regulated to protect children. (nutrition-nutritionists.com)
  • In addition to providing emergency advice on the management of poisoning cases, poisons centres compile data on toxic exposures and on toxic substances. (who.int)
  • In Wistar rats, maternal exposure to nicotine was shown to impair the inhibitory function of perivascular adipose tissue on vascular contractility in the aorta of the offspring. (mcmaster.ca)
  • Becker found that female rats were more likely to use cocaine when circulating estrogen was high, but also that progesterone could counter the effects of estrogen. (sfn.org)
  • Further, she found that the administration of estrogen had no effects on self-administration in male rats. (sfn.org)
  • A preclinical study in rabbits and rats investigated the effects of aescin on healing of tibia fracture and abdominal wound after surgery. (viatrisconnect-sa.com)
  • The general Health effects are determined between DEHP exposure and risk of Di(2-ethylhexyl)phthalate, commonly population may also be exposed through by the dose (how much), the allergy and asthma in humans is referred to as DEHP, is a manufactured ambient air. (cdc.gov)
  • Since Zika virus (ZIKV) first emerged as a public health concern in 2015, our ability to identify and track the long-term neurological sequelae of prenatal Zika virus (ZIKV) infection in humans has been limited. (bvsalud.org)
  • The maximum systemic exposure of the mice in this study was 0.7 times the maximum possible systemic exposure in humans. (sdrugs.com)
  • In absence of data to the contrary, assume that the toxicokinetics is the same in animals and humans under similar exposure conditions. (cdc.gov)
  • Animals that have similar toxicokinetics to humans likely serve as good predictors of harmful effects in humans. (cdc.gov)
  • Understanding the basic or specific biologic changes that ultimately lead to clinical disease in a test animal can help health assessors determine how well animal models might predict the similar adverse effect in humans. (cdc.gov)
  • Many pregnant women use such medications without prior consideration to the adverse effects of these substances on their unborn children. (medscape.com)
  • It is well known that SHS exposure brings about almost the same adverse health outcomes as active smoking [ 3 ]. (biomedcentral.com)
  • Introduction: Previous studies have suggested adverse effects of maternal exposure to air pollution on neurodevelopment in early childhood. (ewha.ac.kr)
  • The frequency of these ranges from 0.9% to 3% across experiments, and several studies have found no more adverse effects with horse chestnut seed extracts that with placebo. (viatrisconnect-sa.com)
  • Most of the contaminants were found in almost all the participants, but less than one per cent of the samples had levels that exceeded current thresholds for increased risk of adverse health effects. (phys.org)
  • Whether an exposure could lead to an adverse health outcome depends on the characteristics of exposure and the exposed population (e.g., developmental stage, existing disease state, genetic factors) that could make them more susceptible to site-related exposures. (cdc.gov)
  • The results would provide theoretical basis to protect vulnerable population defined by birth season when exploring the adverse effects of ambient PM 2.5 in the respiratory health. (biomedcentral.com)
  • In a poster abstract presented at the American Society of Health-System Pharmacists Midyear Clinical Meeting & Exhibition held in Anaheim, California, stress ulcer prophylaxis (SUP) did not appear to provide benefit for prevention of gastrointestinal bleeding and did not increase SUP-associated adverse effects. (contemporarypediatrics.com)
  • This effect might be modified by genetic polymorphism and breastfeeding behavior. (biomedcentral.com)
  • These types of disabilities can have a number of causes, including infections, genetic conditions, exposure to toxins, and trauma. (bila.ca)
  • Similarly, vision delays may be caused by genetic conditions such as infantile cataracts, strabismus (cross eyes), or amblyopia (lazy eye). (bila.ca)
  • 6.1 Mutagenicity and carcinogenicity A major reason for research into the effects of cannabinoids on cellular processes is to discover whether cannabinoids are mutagenic, i.e. whether they may produce mutations in the genetic material in the somatic and germ cells of users. (druglibrary.org)
  • If cannabinoid exposure affects the genetic material of a user's somatic or bodily cells (such as those of the lung, for example) then chronic cannabis use may cause cancer. (druglibrary.org)
  • A few studies have found a higher risk of autism and of lower cognitive functioning in children living near freeways, but results of studies about how prenatal and early childhood exposure to air pollution might affect development have been inconsistent. (nih.gov)
  • Therefore, SHS exposure should be considered a modifiable risk factor for delayed neurodevelopment and cognitive impairment in children. (biomedcentral.com)
  • The present study tested the hypothesis that prenatal exposures to a non-AChE-inhibiting dose of malathion are causally related to sex-biased cognitive deficits later in life in a precocial species. (nih.gov)
  • Perhaps more disturbing is that children are susceptible to exposure based on their cognitive development. (kevinmd.com)
  • A longitudinal study of Adolescent Brain Cognitive Development (ABCD) showed an increased mental health burden with prenatal cannabis exposure that persists from childhood to early adolescence. (kevinmd.com)
  • Other possible causes of motor skill delays include cerebral palsy , cognitive delays, spina bifida, ataxia, myopathy, and problems with vision. (bila.ca)
  • High exposure in children can leave residual cognitive deficits. (cdc.gov)
  • BACKGROUND: The role of tobacco smoke exposure in the development and persistence of asthma and rhinoconjunctivitis through childhood into adolescence is unclear. (lu.se)
  • OBJECTIVES: We assessed the associations of parental smoking from fetal life through adolescence with asthma and rhinoconjunctivitis during childhood and adolescence. (lu.se)
  • Tobacco smoke exposure during fetal life, infancy, childhood, and adolescence was not associated with adolescent-onset asthma or rhinoconjunctivitis. (lu.se)
  • CONCLUSIONS: Findings from this combined analysis of five European birth cohorts strengthen evidence linking early exposure to tobacco smoke with asthma during childhood and adolescence. (lu.se)
  • These results led the researchers to conclude that early childhood exposure to air pollutants may convey a higher risk for developmental delays, compared to similar exposures in the womb. (nih.gov)
  • The strongest association was seen for having a mother who performed farm activities while pregnant (Odds Ratio=0.60, 95% Confidence Interval=0.48-0.74) and remained significant in models with correlated early-life exposures including early childhood farm animal contact and raw milk consumption. (cdc.gov)
  • These results extend previous work done primarily on childhood outcomes and suggest that protective associations of early-life farm ing exposures on atopy endure across the life-course. (cdc.gov)
  • To condense evidence about risk and protective factors for childhood asthma and/or wheezing disorders occurred in the first 1,000 days of life. (bvsalud.org)
  • Several modifiable behaviors or exposures can be associated with asthma and wheezing in childhood. (bvsalud.org)
  • Prenatal and childhood influences on osteoporosis. (ox.ac.uk)
  • In addition to these modifiable factors during childhood, evidence has also accrued that the risk of fracture might be programmed during intrauterine life. (ox.ac.uk)
  • The overall aim of this thesis was to evaluate the associations between prenatal exposure to EDC mixtures and nutrition respectively, with birthweight, growth and body composition in early- and mid-childhood, and to determine if these associations differed by sex. (diva-portal.org)
  • Results suggest that higher prenatal exposure to EDC mixtures were associated with lower birthweight, and slower weight gain in early childhood, including a later peak growth velocity among girls. (diva-portal.org)
  • Conclusions: The findings suggest that exposure to air pollution may result in delayed neurodevelopment in early childhood. (ewha.ac.kr)
  • There could be major Childhood Trauma: The Impact of Childhood Adversity on Education, Learning, and Development compounding effects if the stereotype threat associated with a child's identity status is likely to increase the difficulties a child displays in a given neurocognitive domain. (ubbcluj.ro)
  • For example, EPA's IEUBK Model external icon is a type of PBPK model that ATSDR health assessors should use when evaluating childhood exposure to lead in soil. (cdc.gov)
  • Prenatal and early childhood exposure has been linked to low birth weights , developmental delays and other health effects. (panna.org)
  • In conclusion, prenatal exposure to both EDC mixtures and nutrition suggests to have an influence on birthweight, and children´s growth. (diva-portal.org)
  • Results show that higher levels of EDC mixtures were associated with lower birthweight, slower weight gain, and sex-specific effects on body fat. (diva-portal.org)
  • Although effects of prenatal exposure to SHS on early neurodevelopment vary among studies, they remain significant issues. (biomedcentral.com)
  • Here, we use this model in conjunction with longitudinal magnetic resonance imaging (MRI) to expand our understanding of the long-term neurological consequences of prenatal ZIKV infection in order to identify characteristic neurodevelopmental changes and track them across time. (bvsalud.org)
  • BACKGROUND: Smoke-free legislation eliminating tobacco smoke in all indoor public places and workplaces is the international standard to protect all people from exposure to secondhand smoke. (who.int)
  • Exposure to active smoking and secondhand smoke (SHS) causes health concern. (biomedcentral.com)
  • The effects of chemicals, such as opiates, cocaine, nicotine, alcohol, and new recreational drugs, on fetal development have been seriously studied only in the last 30-40 years. (medscape.com)
  • Here we studied the blood pressure effects and the alteration of perivascular adipose tissue function in mesenteric arteries of the offspring born to Wistar-Kyoto rat (WKY) dams exposed to nicotine. (mcmaster.ca)
  • In mesenteric arteries from control offspring, contractile responses induced by phenylephrine, serotonin, and 9,11-dideoxy-11alpha, 9alpha-epoxymethanoprostaglandin F(2)alpha (U44619) were significantly attenuated in the presence of perivascular adipose tissue, an effect not observed in the nicotine-exposed tissues. (mcmaster.ca)
  • Purpose Research reveals that prenatal alcohol exposure and child trauma (i.e., abuse, neglect, sexual abuse) can have deleterious effects on child development across multiple domains. (ubbcluj.ro)
  • The first 1,000 days of life of a child, the period from conception to the end of the second year, is a critical stage for the development of respiratory and immune systems. (bvsalud.org)
  • 6. The chronic effects of cannabis use on health Cellular and immunological effects The possible effects of chronic cannabis use on cellular processes and the immune system are considered together because both effects may influence a cannabis user's susceptibility to diseases. (druglibrary.org)
  • 6.2 Immunological effects The possibility that cannabis reduces immune system function is important for several reasons. (druglibrary.org)
  • It is not clear why exposure to pollutants after birth is linked to a higher risk of developmental delay," said Sandie Ha, Ph.D., of the Department of Public Health at the University of California, Merced, and lead author of the study. (nih.gov)
  • What Is a Developmental Delay? (bila.ca)
  • If a child has not reached a particular milestone, then it may be a sign that they have a developmental delay. (bila.ca)
  • preferred biomarker of exposure. (cdc.gov)
  • High correlations between levels in mothers and their children were observed for these compounds, showing that maternal exposure is important for the child's levels many years after birth," she concludes. (phys.org)
  • Therefore, more attention should be paid to pregnant women and infants who are susceptible to SHS exposure. (biomedcentral.com)
  • Women tend to try cocaine earlier in life, susceptible individuals become addicted faster, and, once addicted, they suffer worse damage to their brains, hearts, and livers as a result of their cocaine use, compared with men. (sfn.org)
  • Conclusions: In a large US farm ing population, early-life farm exposures, particularly maternal farm ing activities while pregnant, were strongly associated with reduced risk of atopy in adults. (cdc.gov)
  • There are other theories for poor development in infants, but this is a real problem and warrants care for pregnant mothers and their exposure to chemicals. (nutrition-nutritionists.com)
  • Liggins also discovered that cortisol given to pregnant mothers helped delay premature labor, and that it increased the likelihood that premature infants would breathe normally after birth. (asu.edu)
  • Conclusion Maternal interpersonal trauma exposures can negatively impact child social-emotional development, acting in part through maternal psychosocial factors. (ubbcluj.ro)
  • Air hexyl)phthalate from medical procedures such as blood (and lung during inhalation exposure). (cdc.gov)
  • Early-life farm exposures and adult asthma and atopy in the Agricultur al Lung Health Study. (cdc.gov)
  • Birth season which reflects the early-life PM 2.5 exposure level that may influence the lung development has a potential effect on the disease burden of respiratory diseases related to ambient PM 2.5 exposure in later life. (biomedcentral.com)
  • If it is the non-cannabinoid components of cannabis smoke that are mutagenic, then any cancers caused by cannabis smoking are most likely to develop after long-term exposure to cannabis smoke, and they are most likely to develop at sites which have had the maximum exposure to that smoke, namely, the upper aerodigestive tract and lung. (druglibrary.org)
  • The researchers also estimated exposures to ozone and fine inhalable particles ( PM2.5 ), two pollutants produced by car traffic. (nih.gov)
  • Prenatal exposure to elevated PM2.5 led to a 1.6 to 2.7 percent higher risk of failing any developmental domain, while higher ozone exposure led to a .7 to 1.7 percent higher risk of failing a developmental domain. (nih.gov)
  • Prenatal stress (PNS) is associated with increased biological risk for mental disorders such as anxiety and depression later in life, an. (nel.edu)
  • Although the full spectrum of physical damage that drugs of abuse can cause cannot be documented, one thing is certain: the effect of maternal drug use on fetal brain development is the most critical and most studied effect. (medscape.com)
  • The external elements and conditions which surround, influence, and affect the life and development of an organism or population. (lookformedical.com)
  • Endocrine disrupting chemicals (EDCs) are man-made chemicals, common in everyday population exposure, and have been associated with unfavorable health effects and development. (diva-portal.org)
  • Brain development can be altered by cannabis exposure. (kevinmd.com)
  • This follows the evidence that cannabis has genotoxic effects on sperm and human development. (kevinmd.com)
  • Delays in the development of gross or fine motor skills are often caused by preterm birth, as children who are born prematurely may not develop muscles at the same rate as children who were born full-term. (bila.ca)
  • Or, more precisely, your baby's brain, which undergoes vital development in those first few months of life. (mashed.com)
  • For starters, a zinc deficiency in these formative years can cause growth and development delays. (mashed.com)
  • Because hormones play a critical role in early development, toxicological effects on the endocrine system often have an impact on the reproductive system. (benjaminbarber.org)
  • Several researchers have used the exposure of human foetuses to DES as a model for the prenatal effects of estrogens on development . (benjaminbarber.org)
  • Hormones will coordinate the development of each individual from a single fertilized cell, and will help that developing organism to cover the needs of each of its organs through the different stages of its life. (ivis.org)
  • Exposure to these chemicals during early fetal development can cause brain injury at doses much lower than those affecting adult brain function. (nutrition-nutritionists.com)
  • Prenatal alcohol (ethanol) exposure can have dramatic effects on the development of the central nervous system (CNS), including morphological abnormalities and an overall reduction in white matter of the brain. (asu.edu)
  • Most patients with this condition also exhibit delayed development. (e-cep.org)
  • Infantile spasms (IS), also known as West syndrome, is an age-specific epileptic seizure and the majority of patients with this condition also exhibit symptoms of delayed development. (e-cep.org)
  • Therefore, we hypothesized that there may be a protein that acts as a tumor inhibitor during these early stages of life, preventing the development of leukemia. (lu.se)
  • In paper I, we used a mouse model that generates leukemia, and we tested the effect of LIN28B expression on leukemia development. (lu.se)
  • Our study suggests that exposure to long-term prenatal stress results in increased susceptibility to seizures. (e-cep.org)
  • The purpose of the study was to describe the neurodevelopmental outcomes in children exposed to Zika virus during fetal life, with and without microcephaly at birth. (bvsalud.org)
  • We outline the early epidemiology of EVD within Liberia, including the practical limitations on surveillance and the effect on the country's health care system, such as infections among health care workers. (cdc.gov)
  • The study considered many families of chemicals, including some where health effects are suspected or plausible. (phys.org)
  • The eyebrow-raising study found men with higher levels of exposure to polyfluorinated chemicals (PFCs) had penises that were 12.5 per cent shorter and 6.3 per cent thinner than other men. (stackexchange.com)
  • and does measured exposure to the chemicals have a association at the common dosage people might face in normal life? (stackexchange.com)
  • The AT also plays a role in the toxicokinetics of POPs since it can store these chemicals for a long time and, in that sense, may be protective during acute exposure. (ecog-obesity.eu)
  • The term endocrine disruptor is used to describe chemicals that can mimic hormones and may either enhance or counteract their effects. (benjaminbarber.org)
  • Publicity about these possible effects is being used to support demands for tighter emission controls and for drastic changes in the use of industrial chemicals and pesticides. (benjaminbarber.org)
  • Another 200 chemicals are known to cause clinical neurotoxic effects in adults. (nutrition-nutritionists.com)
  • The most recent estimates of the burden of disease attributable to chemicals indicate that in 2016, an estimated 1.6 million lives were lost due to exposures to selected chemicals.1 However, data are available for only a small number of chemicals, and people are exposed to many more chemicals in their daily lives. (who.int)
  • 2. Critically assess both the strengths and weaknesses of these three life-course perspectives in their ability to explain racial disparities in maternal and infant health outcomes. (nlsinfo.org)
  • 3. Explain how race and SES interact to affect health outcomes over the life-course. (nlsinfo.org)
  • A recent study in JAMA Network Open investigates the impact of extrauterine placental perfusion versus delayed cord clamping on hematocrit levels in newborns, shedding light on potential alternatives for optimizing infant outcomes during birth. (contemporarypediatrics.com)
  • Hormones are crucial in an individual's life, and a deficiency or failure in the endocrine system can lead to illness or even death. (ivis.org)
  • Pesticides that behave like the female hormone estrogens can have serious effects on reproductive success and function on animal exposed to them. (benjaminbarber.org)
  • Prenatal diagnosis and advanced reproductive technologies to decrease the risk of an affected offspring should be discussed. (acog.org)
  • Women's childbearing intentions may change throughout their reproductive life because of the In this study, we aimed to determine the change (or direct and indirect costs of parenting, according to their stability) in individual fertility preferences of women partner's wishes, and whether their relationship is stable of reproductive age in Türkiye during the COVID-19 or not ( 5 ). (who.int)
  • Men play a substantial role in prenatal health. (susansmithjones.com)
  • Although these prevention campaigns are highly successful, most were initiated only after substantial delays. (nutrition-nutritionists.com)
  • Monitoring by PANNA and community groups in Washington state and Luis Medellin's hometown of Lindsay, California has shown that daily exposure to chlorpyrifos can be substantial, regularly exceeding the "acceptable" 24-hour acute dose for a one-year-old child established by the EPA. (panna.org)
  • Its expression is highest during the prenatal period and decreases abruptly after birth. (lu.se)
  • However, this strategy has not lowered the incidence of hepatitis B, primarily because vaccinating persons engaged in high-risk behaviors, life-styles, or occupations before they become infected generally has not been feasible. (cdc.gov)
  • Although the modifications of traditional demographic characteristics in the health effects of PM 2.5 exposure are frequently analyzed, the impact of birth season is rarely taken into consideration. (biomedcentral.com)
  • Little is known about the… The long-term consequences of trauma exposure, such as substance abuse, incarceration, and co-occurring psychiatric problems are discussed along with the importance of recognizing protective factors, examining resiliency, and identifying empirically based treatment modalities to help alleviate symptoms of trauma survivors. (ubbcluj.ro)
  • This delay can cause children to consume more gummies before symptoms take effect. (kevinmd.com)
  • The symptoms of cannabis poisoning in children show up as effects on the brain. (kevinmd.com)
  • The most likely routes of exposure for DEHP is absorbed via inhalation, oral, DEHP and/or its metabolites (MEHP, ToxG uideTM the general public to DEHP are through and dermal routes. (cdc.gov)
  • SAN DIEGO, November 5, 2007 - Females seem to be unequally disposed to the harmful effects of stress and to addiction compared with males. (sfn.org)
  • There is also an international treaty to protect people and the environment from the harmful effects of mercury," she continues. (phys.org)
  • 8) have previously demonstrated that prenatal exposure to acute immobilization stress (AIS) leads to increased susceptibility to IS. (e-cep.org)
  • Thus, we investigate the effect of long-term prenatal stress on the GABAergic signaling system by using acute and chronic immobilization stress (CIS) models. (e-cep.org)
  • Short-term ambient PM 2.5 exposure is associated with increased mortality of respiratory diseases. (biomedcentral.com)
  • However, few evidence was available on the effect of exposure to ambient PM 2.5 on the years of life lost (YLL) from respiratory diseases in the elderly. (biomedcentral.com)
  • Nevertheless, the modification effect of birth season on the relationship of PM 2.5 exposure and respiratory health need to be explored. (biomedcentral.com)
  • A time-stratified case-crossover design was used to analyze YLL from respiratory diseases in the elderly related to ambient PM 2.5 exposure between 2013 and 2016 in Ningbo, China. (biomedcentral.com)
  • Individuals who were born in winter had significantly higher YLL from respiratory diseases associated with ambient PM 2.5 exposure than those who were born in other seasons. (biomedcentral.com)
  • In addition, studies exploring the effect of ambient PM 2.5 exposure on the years of life lost (YLL) from respiratory diseases are scarce. (biomedcentral.com)
  • Given that a large proportion of the U.S. population lives close to major roadways, which are major sources of air pollution, the researchers sought to determine if living near heavily traveled roads was linked to lower scores on developmental screens -questionnaires or checklists that indicate whether a child is developing normally or needs to be referred to a specialist for further testing. (nih.gov)
  • Current asthma and early-life farm ing exposures were assessed via questionnaires. (cdc.gov)
  • Find out about the exciting discoveries being made by NIEHS and NIEHS-supported researchers that are helping to improve health and save lives. (nih.gov)
  • This section provides an overview of how to examine factors that influence whether an exposure to a contaminant could produce harmful health effects and how these factors weigh into your public health conclusions. (cdc.gov)
  • As depicted in the figure below, multiple factors influence whether an exposure could result in harmful health effects, as well as the type and severity of those health effects. (cdc.gov)
  • When available, health assessors can refer to the toxicokinetic data analysis included in the MRL summary in the Toxicological Profile, which presents methods for extrapolating animal data to human exposure. (cdc.gov)
  • These factors in the early life may influence the health outcome in later life. (biomedcentral.com)
  • According to Bloch (1983) who reviewed the literature for the World Health Organisation: 'in vivo and in vitro exposure to purified cannabinoids or cannabis resin failed to increase the frequency of chromosomal damage or mutagenesis' (p412). (druglibrary.org)
  • Differences in adult health are thought to be partially rooted in the early conditions of life, and class disparities. (nlsinfo.org)
  • 1. Describe three models of life-course processes typically used to explain population-level health trends in the U.S. (nlsinfo.org)
  • A recent study was highlighted at the 2023 American Academy of Pediatrics National Conference & Exhibition that shed light on the long-term impact of very preterm birth on the health-related quality of life (HRQOL) of infants and identified key determinants. (contemporarypediatrics.com)
  • NIOSH IDLH (immediately dangerous to life or health) = 100 mg/m 3 (NIOSH 2005). (cdc.gov)
  • Use of Sheng-Hua-Tang and health-related quality of life in postpartum women: a population-based cohort study in Taiwan. (precisionenvironmed.com)
  • Use of herbal dietary supplement Si-Wu-Tang and health-related quality of life in postpartum women: a population-based correlational study. (precisionenvironmed.com)
  • Women's perceptions of their husband's drinking behavior as a risk factor of their health-related quality of life in the postpartum period. (precisionenvironmed.com)
  • The COVID-19 pandemic affected economic and developed countries but there was a return to normal social life as well as physical health. (who.int)
  • Children with high early-life exposure were more likely than unexposed children to have early transient and persistent asthma and persistent rhinoconjunctivitis. (lu.se)
  • Objective: To examine associations between early-life farm ing exposures and current asthma and atopy in an older adult US farm ing population. (cdc.gov)
  • We used logistic regression, adjusted for age, sex, race, state (Iowa or North Carolina), and smoking (pack-years), to estimate associations between early-life exposures and asthma (1,198 cases and 2,031 non-cases) or atopy (578 cases and 2,526 non-cases). (cdc.gov)
  • Effect of mattress and pillow encasings on children with asthma and house dust mite allergy. (cdc.gov)
  • Duration of breast feeding and risk of developmental delays in Taiwanese children: a nationwide birth cohort study. (precisionenvironmed.com)
  • Third, if cannabinoids have immunosuppressive effects, then this would have mixed implications for their therapeutic use. (druglibrary.org)
  • This could lead to muscle dysfunction and thus to impairments of exercise and quality of life (QOL). (who.int)
  • The effects on brain function associated with prenatal methylmercury exposure therefore appear widespread, and early dysfunction is detectable at exposure levels currently considered safe. (pure.fo)
  • Effect of a chronic illness/organ dysfunction. (familydoctor.co.nz)
  • However, prenatal exposures to malathion levels that are below the threshold for AChE inhibition have been associated with increased risks of neurodevelopmental disorders, including autism spectrum disorder with intellectual disability comorbidity. (nih.gov)
  • Since shelf life, colorings, and flavor enhancers are important factors, a great many additives are included. (jonathanturley.org)
  • Certain "protective factors" can help reduce the effects of FASDs and help people who have them reach their full potential. (medlineplus.gov)
  • Considering the impressive number of WP smokers, we intend to investigate the potential effect of WPS on submaximal exercise capacity and QOL. (who.int)
  • The levels varied a lot between the six countries, which shows that country of residence is a strong determinant of your personal exposure. (phys.org)
  • This poses two questions: is the effect significant at the exposure levels reported in the study ? (stackexchange.com)
  • and did the study define the exposure levels of significance. (stackexchange.com)
  • Even when not infected during the perinatal period, children of HBV-infected mothers remain at high risk of acquiring chronic HBV infection by person-to-person (horizontal) transmission during the first 5 years of life (10). (cdc.gov)
  • Children who are blind or who have vision difficulties are likely to have delayed exploration skills and take longer to walk (18 to 24 months). (familydoctor.co.nz)
  • Deaf children are likely to have delayed language milestones. (familydoctor.co.nz)
  • Ingestion is the main route of exposure for the general population, particularly children (ATSDR 2005). (cdc.gov)
  • For children, the most common source of lead exposure is lead-based paint deteriorated into chips and lead dusts (CDC 1997). (cdc.gov)
  • These children and their families are under continuous mental and physical stress and require comprehensive services in order to help the children have a near normal life [7-11]. (who.int)
  • This cohort study examined the relationship between VOC exposure and fetal growth retardation (measured as SGA and decreased MBW) and preterm delivery in three groups with different exposures to contaminated drinking water and in an unexposed comparison population. (cdc.gov)
  • Common conditions associated with developmental delays include autism spectrum disorder, cerebral palsy, intellectual disabilities, muscular dystrophy, fetal alcohol spectrum disorder, or a rare condition such as Fragile X Syndrome. (bila.ca)
  • More severe developmental delays come to parents and doctors attention earlier - this includes mental retardation, cerebral palsy and vision problems. (familydoctor.co.nz)
  • The study is associational and so cannot prove cause and effect. (nih.gov)
  • It seems to me on a quick read that the study was much more careful than the headline and the link to normal exposure is spurious. (stackexchange.com)
  • A 2015 study published by the U.S. National Library of Medicine similarly addresses the importance of lutein's neuroprotective effects. (mashed.com)
  • This study aimed to determine the effect of long-term prenatal stress on susceptibility to infantile spasms. (e-cep.org)
  • Inhalation - Likely route of exposure for Evidence for potential associations the occupational population. (cdc.gov)