• cohort
  • 129 Likewise, in a cohort of 811 aging men, subjects reporting higher stress levels scored lower on the Mini-Mental State Examination than their low-stress counterparts. (lifeextension.com)
  • We report the association of adult SBP and diastolic BP (DBP) with determinants of fetal growth, 28 size at birth, and growth in infancy and examine whether these associations were modified by factors such as current body size or socioeconomic status (SES) in extensive prospective data from the fetal period until 31 years from the Northern Finland 1966 Birth Cohort (NFBC 1966). (ahajournals.org)
  • Job demand and control in mid-life and physical and mental functioning in early old age: do childhood factors explain these associations in a British birth cohort? (bmj.com)
  • Using data from a nationally representative British birth cohort followed up across life to early old age, we were able to use prospectively collected data on job demand and control in mid-life and self-reported mental and physical functioning in early old age. (bmj.com)
  • Although this might introduce bias, the cohort have been found at age 53 to be representative in most respects of the national population born at a similar time and the distribution of occupational class and unemployment at ages 60-64 was similar to the 2001 England Census reference population. (bmj.com)
  • cognitive
  • Interestingly, depression seems to worsen cognitive dysfunction, but poorer cognitive health predisposes aging individuals to depression as well. (lifeextension.com)
  • In fact, studies designed specifically to assess age-related cognitive performance in depression show an interrelationship between the two conditions. (lifeextension.com)
  • A group of aging subjects diagnosed with depression completed various cognitive tests and their results were compared to those of age and sex - matched, non-depressed control subjects. (lifeextension.com)
  • Adjustment for childhood factors (father's and mother's educational attainment, parents' interest in school at age 7 and cognitive ability at age 8) partially explained the association between job control and physical functioning, but did not explain the association between job demand and mental functioning. (bmj.com)
  • Research on animals finds that environmental enrichment could aid the treatment and recovery of numerous brain-related dysfunctions, including Alzheimer's disease and those connected to aging, whereas a lack of stimulation might impair cognitive development. (wikipedia.org)
  • The study including reviews of autobiographical essays by the nuns upon joining the order, administration of memory and cognitive tests to the nuns (some over 100 years of age), and post-mortem examination of their brains. (wikipedia.org)
  • 1996) Linguistic ability in early life and cognitive function and Alzheimer's disease in late life: Findings from the Nun Study. (wikipedia.org)
  • cognition
  • The conclusion drawn from this evidence was that " late-life depression is characterized by slowed information processing, which affects all realms of cognition . (lifeextension.com)
  • They had, in 1989, started a study of age-associated changes in cognition and function in a group of older adults in Kentucky who had agreed to brain donation at death. (wikipedia.org)
  • facets
  • However, more loosely defined facets of our lives related to our psychological condition contribute to our mental fluency as well. (lifeextension.com)
  • A table of the personality dimensions measured by the NEO PI-R, including facets, is as follows: In the 1970s, Paul Costa and Robert McCrae were researching age-related changes in personality. (wikipedia.org)
  • In 1992 Costa and McCrae published a Revised NEO manual which included six facets for each factor (30 in total). (wikipedia.org)
  • childhood
  • Objectives Adverse work-related exposures have been linked with decreased physical and mental functioning in later life, however, whether childhood factors explain the associations between work exposures and functioning is unknown. (bmj.com)
  • Our aim was to investigate if job demand and control in mid-life were related to self-reported physical and mental functioning in early old age and whether childhood factors explained these associations. (bmj.com)
  • Conclusions Job demand and control in mid-life are differentially associated with mental and physical functioning in early old age and some of these associations may be partially explained by childhood factors. (bmj.com)
  • With the availability of a wealth of prospectively collected data on factors in childhood we were able to explore the influence of these on the main associations of interest which few other studies are able to do. (bmj.com)
  • behavior
  • A person's personality profile is thus gauged from their standing on five broad concepts which predict, among other life outcomes, behavior and the quality of interpersonal relationships. (wikipedia.org)
  • citation needed] This school of thought attributes human behavior to environmental factors, relegating individual differences to situational artifacts and contesting the existence of individual predispositions. (wikipedia.org)
  • Thus
  • Thus, if you strengthen your income and intellectual areas of your life, then your perfect age will start getting up into your 40s, 50s and even 60s. (thelisttv.com)
  • Thus, an actuary can reasonably estimate the average age of death for a group of 25-year-old males, who don't smoke. (wikipedia.org)
  • genetic
  • Grillari, Johannes 2017-03-15 00:00:00 Mechanisms that ensure and maintain the stability of genetic information are fundamentally important for organismal function and can have a large impact on disease, aging, and life span. (deepdyve.com)
  • About 90-95% of cases are primary, defined as high blood pressure due to nonspecific lifestyle and genetic factors. (wikipedia.org)
  • whereas
  • For example, the NEO PI-R consists of 240 items (questions), whereas the shorter NEO-FFI (NEO Five-Factor Inventory) has only 60 items (12 per domain). (wikipedia.org)
  • findings
  • The great diversity in plant life and altitudinal-determined microenvironments that surrounded the marsh helped to make it a popular place to live, as evidenced by archaeological findings. (wikipedia.org)
  • physiological
  • With the patient in a prone or seated position, the medical professional will look at both breasts to check the color, symmetry, dimensions according to age, lean body mass, the physiological (pregnancy and lactation) and race, looking for abnormalities, such as bulges and shrinkage. (wikipedia.org)
  • known
  • A precise multiplier, known as the Acceleration Factor (AF) simulates long lifetime operation. (wikipedia.org)
  • Based on data from the Baltimore study, Costa and McCrae recognized two additional factors: Agreeableness (A) and Conscientiousness (C). Accordingly, in 1985 they published the first manual for the NEO that included all five factors, which are now known as the Big Five personality traits. (wikipedia.org)
  • It has long been believed that personality development is shaped by life experiences that intensify the propensities that led individuals to those experiences in the first place, which is known as the corresponsive principle. (wikipedia.org)
  • factors such as age and gender are known to impact it. (wikipedia.org)
  • healthy
  • Although senior citizens can also qualify for a whole life insurance plan if they are healthy, the premiums will be more expensive. (prweb.com)
  • include
  • contributing factors include retirees living longer (increasing the relative number of retirees), and lower birth rates (decreasing the relative number of workers, especially relative to the Post-WW2 Baby Boom). (wikipedia.org)
  • cellular
  • As such, cellular senescence represents a change in "cell state" rather than a cell becoming "aged" as the name confusingly suggests. (wikipedia.org)
  • These results highlight the independence of cellular senescence from epigenetic aging. (wikipedia.org)
  • Consistent with this, telomerase-immortalised cells continued to age (according to the epigenetic clock) without having been treated with any senescence inducers or DNA-damaging agents, re-affirming the independence of the process of epigenetic ageing from telomeres, cellular senescence, and the DNA damage response pathway. (wikipedia.org)
  • suggests
  • It's been called the 'Goldilocks Theory' of marriage, because data suggests the divorce rate is higher if you get hitched outside of that age range. (thelisttv.com)
  • metabolic
  • Our country is experiencing an epidemic of age-related disorders like diabetes, metabolic syndrome and heart disease. (flipboard.com)
  • This can be attributed to extremely variable hepatic and renal metabolic functions among individuals depending upon a number of factors (including age, ethnicity, disease, and current or previous use/abuse of other drugs/medicines). (wikipedia.org)
  • Long
  • Long life tyres are made from a harder compound and may be noisier as a result. (theaa.ie)
  • There are three lift practices that go a long way in covering the Marks Of Time: These Factors Give Away Your True Age . (arogalifehealth.us)
  • Prospective
  • Attrition in prospective studies with follow-up across the whole of life is to be expected. (bmj.com)
  • stress
  • In a study involving 36 women between the ages of 25 and 53, those with the highest work-related stress levels displayed decreased attention and visuo-spatial memory. (lifeextension.com)
  • This reliability stress test is sometimes referred to as a "lifetime test", "device life test" or "extended burn in test" and is used to trigger potential failure modes and assess IC lifetime. (wikipedia.org)
  • The digital toggling factor (DTF) represents the number of transistors that change their state during the stress test, relative to the total number of gates in the digital portion of the IC. (wikipedia.org)
  • The degrees of freedom for aligning the aging magnitude of analog parts is usually the duty-cycle, external load values and voltage stress. (wikipedia.org)
  • health
  • Fasttermlifeinsurance.com is an online provider of life, home, health, and auto insurance quotes. (prweb.com)
  • stronger
  • Among females, gestational age showed a stronger association with blood pressure than birth weight: gestational age higher by 7 weeks (equivalent to an average of 1 kg higher birth weight) among singletons associated with −2.9 (95% CI, −4.7, −1.1) mm Hg lower systolic blood pressure. (ahajournals.org)
  • research
  • The treatment for such metastasis disease is continuously demanding more research to determine the most effective, and life saving treatments. (openpr.com)
  • The assessment at this time included six facet sub-scales for the three original factors (N, E, & O). This naming convention continued with the third version, with the Revised NEO Personality Inventory, published in 1990,[citation needed] being referred to as NEO PI-R. Research began to accumulate that indicated that the five factors were sufficiently broad and useful. (wikipedia.org)
  • Longitudinal research demonstrates that people's personality trajectories can often be explained by the social roles they espoused and relinquished throughout their life stages. (wikipedia.org)
  • different
  • Dr. Jay Olshansky, who researches how to slow down the aging process, says he's heard many different answers, and is now helping us build the perfect age. (thelisttv.com)
  • Different parts of the body may age at different rates. (wikipedia.org)
  • Methods
  • In property and casualty insurance, there are three basic rate-making methods: Judgment Rating is used when the factors that determine potential losses are varied and cannot easily be quantified. (wikipedia.org)
  • impact
  • The ways in which the brain is utilized and stimulated impact its functional state at all ages. (lifeextension.com)
  • The Age of the Fall was a professional wrestling stable, primarily in Ring of Honor and its sister promotion Full Impact Pro, but also in other independent promotions such as Pro Wrestling Guerrilla. (wikipedia.org)
  • adults
  • the revised instrument was administered to new samples The NEO PI-R and a revised version of the instrument were administered to 500 adolescents, 635 adults, and 449 middle school age children (12-13 year old). (wikipedia.org)
  • data
  • 2,10,13,24 These have a number of potential limitations including retrospective data collection and an incomplete consideration of confounding factors operating throughout the life course. (ahajournals.org)
  • 1485 occupationally active study members had data available on job demand and control in mid-life and on physical and mental functioning assessed using the Short Form-36 questionnaire at 60-64 years. (bmj.com)
  • individual factors
  • Approaches through social, economic and individual factors, such as brand loyalty, have been considered along with the more widely recognized geographic, physiographic, demographic and behavioral variables proposed by Philip Kotler. (wikipedia.org)
  • study
  • Yep, according to a National Academy of Science study, your best life might be at the age when you'd least expect it. (thelisttv.com)
  • The homogeneous life style of the nuns makes them an ideal study population. (wikipedia.org)
  • Snowdon's book on the Nun study, Aging with Grace: What the Nun Study Teaches Us About Leading Longer, Healthier, and More Meaningful Lives, won a Christopher Award in 2002. (wikipedia.org)
  • Effects
  • IGF-1 has also been referred to as a "sulfation factor" and its effects were termed "nonsuppressible insulin-like activity" (NSILA) in the 1970s. (wikipedia.org)
  • relative
  • Birth weight, birth length, gestational age, ponderal index, and birth weight relative to gestational age showed a significant inverse association with blood pressure at age 31. (ahajournals.org)
  • The AF represents the accelerated aging factor relative to the useful life application conditions. (wikipedia.org)
  • found
  • We have previously found that overexpression of the essential human DNA repair and splicing factor SNEV, also called PRP19 or hPso4, extends replicative life span of cultured human endothelial cells and impedes accumulation of DNA damage. (deepdyve.com)
  • As large numbers of skeletons had not previously been found at Great Basin sites, Stillwater Marsh offered a remarkable opportunity to learn about daily life, as reflected in the human remains. (wikipedia.org)
  • higher
  • Results Those with higher job control in mid-life had better physical functioning than those who reported lower job control (β 0.51, 95% CI 0.02 to 1.01, p=0.04 adjusted for adult confounders). (bmj.com)
  • For both the adolescent and adult sample, the item/facet correlations were higher for the revised version of the NEO than for NEO PI-R. In addition, the internal consistency, factor structure, and tests of convergent and discriminant validity suggested that the revised version could be used with middle school children. (wikipedia.org)
  • lifestyle
  • 29 Our a priori hypothesis was that birth measures, in particular birth weight, are linearly and inversely associated with, and change-up infant growth realignment positively associated with, adult SBP/DBP, independent of maternal and other neonatal characteristics, lifestyle factors, and SES. (ahajournals.org)
  • Time
  • Fasttermlifeinsurance.com has released a new blog post explaining when is the best time to buy a whole life insurance policy. (prweb.com)
  • Years
  • We're all aging as we speak - but have you already left your best years behind, or are they yet to come? (thelisttv.com)
  • In addition to swimming, I'm a runner, and over the years the combination of exercise and age led to cartilage degeneration. (lifescript.com)
  • It had been eight years since my last Olympics and I was returning at age 41, 15 months after giving birth to my daughter, and I was competing against athletes half my age. (lifescript.com)
  • The main aim of the HTOL is to age the device such that a short experiment will allow the lifetime of the IC to be predicted (e.g. 1,000 HTOL hours shall predict a minimum of "X" years of operation). (wikipedia.org)
  • people
  • People wanted to know how I got back in shape at my age, what my diet was like and the exercises I did. (lifescript.com)
  • The test was originally developed for use with adult men and women without overt psychopathy, but was later shown to also be useful for people at younger ages. (wikipedia.org)
  • In 1950, there were 7.2 people aged 20-64 for every person of 65 or over in the OECD countries. (wikipedia.org)
  • growth
  • Its primary action is mediated by binding to its specific receptor, the insulin-like growth factor 1 receptor (IGF1R), which is present on many cell types in many tissues. (wikipedia.org)
  • medical citation needed] Insulin-like growth factor 1 has been shown to bind and interact with all the IGF-1 binding proteins (IGFBPs), of which there are seven: IGFBP1, IGFBP2, IGFBP3, IGFBP4, IGFBP5, IGFBP6, and IGFBP7. (wikipedia.org)
  • medical citation needed] Insulin-like growth factor 1 receptor (IGF-1R) and other tyrosine kinase growth factor receptors signal through multiple pathways. (wikipedia.org)
  • human
  • Here, we show that adult-specific overexpression of dPrp19, the D. melanogaster ortholog of human SNEV/PRP19/hPso4, robustly extends life span in female fruit flies. (deepdyve.com)
  • slow
  • Phosphorylation of eukaryotic initiation factor 4e (eif-4E) [4EBP] by mTOR inhibits the capacity of 4EBP to inhibit eif-4E and slow metabolism. (wikipedia.org)