• The one exception is Central centrifugal cicatricial alopecia, which primarily affects women of African ancestry and may occur in several women in the same family. (wikipedia.org)
  • The variation that could be confused with androgenic alopecia in men is central centrifugal cicatricial alopecia (or CCCA). (bernsteinmedical.com)
  • Discoid lupus erythematosus (DLE), Lichen planopilaris (LPP), Frontal fibrosing alopecia, Pseudopelade of brocq, Central centrifugal cicatricial alopecia (CCCA), Folliculitis decalvans and Folliculitis (acne) keloidalis are known as primary cicatricial alopecia. (alopeciacure.com)
  • Central centrifugal cicatricial alopecia (CCCA) belongs to a group of disorders called cicatricial or scarring alopecias that destroy the hair follicle, replace it with scar tissue, and cause permanent hair loss. (darlinghairrestoration.com)
  • One of the most common forms of scarring alopecia is Central Centrifugal Cicatricial Alopecia (CCCA) . (advancetechniquesva.com)
  • In our previous blog post, we covered Central Centrifugal Cicatricial Alopecia (CCCA) which you can read here . (blackvenusbeauty.com)
  • Frontal fibrosing alopecia (FFA): This is a potential clinical variant of lichen planopilaris, with similar histologic features. (medscape.com)
  • Frontal fibrosing alopecia has been associated with the postmenopausal state (ie, postmenopausal frontal fibrosing alopecia), although not all patients with this diagnosis are postmenopausal. (medscape.com)
  • Started as the lichen planopilaris variant, frontal fibrosing alopecia. (medscape.com)
  • classic LPP, frontal fibrosing alopecia , and Lassueur Graham-Little Piccardi syndrome . (rarediseases.org)
  • Frontal fibrosing alopecia is the frontotemporal hairline recession and eyebrow loss in postmenopausal women that is associated with perifollicular erythema, especially along the hairline. (wikipedia.org)
  • Frontal fibrosing alopecia has been most often reported in post-menopausal women with higher levels of affluence and a negative smoking history. (wikipedia.org)
  • Although the pathogenesis of frontal fibrosing alopecia is poorly understood, autoimmune reaction and hormonal factors may play a role. (wikipedia.org)
  • In one study, the use of antiandrogens (finasteride or dutasteride) was associated with improvement in 47% and stabilization in 53% of patients Recently, successful treatment of facial papules in patients with frontal fibrosing alopecia was described with oral isotretinoin. (wikipedia.org)
  • Macdonald A, Clark C, Holmes S. Frontal fibrosing alopecia: a review of 60 cases. (wikipedia.org)
  • Banka N, Mubki T, Bunagan MJ, Mcelwee K, Shapiro J. Frontal fibrosing alopecia: a retrospective clinical review of 62 patients with treatment outcome and long-term follow-up. (wikipedia.org)
  • Pirmez R, Donati A, Valente NS, Sodré CT, Tosti A. Glabellar red dots in frontal fibrosing alopecia: a further clinical sign of vellus follicle involvement. (wikipedia.org)
  • Depression of the frontal veins: A new clinical sign of frontal fibrosing alopecia. (wikipedia.org)
  • Pirmez R, Duque-Estrada B, Donati A, Campos-do-Carmo G, Valente NS, Romiti R, Sodré CT, Tosti A. Clinical and dermoscopic features of lichen planus pigmentosus in 37 patients with frontal fibrosing alopecia. (wikipedia.org)
  • Frontal fibrosing alopecia: a multicenter review of 355 patients. (wikipedia.org)
  • Pirmez R, Duque-Estrada B, Barreto T, Quintella DC, Cuzzi T. Successful Treatment of Facial Papules in Frontal Fibrosing Alopecia with Oral Isotretinoin. (wikipedia.org)
  • Various facial and extrafacial lesions have been reported in frontal fibrosing alopecia (FFA). (karger.com)
  • A . Acute hair loss on the limbs in frontal fibrosing alopecia: a clinicopathological study of two cases . (karger.com)
  • It may also occur in cases of frontal fibrosing alopecia . (hairboutique.com)
  • Sometimes eyebrow transplants may be combined with scalp hair implants, which is frequent in cases of lichen planopilaris (in the form of frontal fibrosing alopecia). (insparya.com)
  • Frontal fibrosing alopecia (FFA) is a chronic form of primary lymphocytic cicatricial alopecia characteristically involving the frontotemporal hairline and eyebrows. (mhmedical.com)
  • It is controversial whether patients with frontal fibrosing alopecia who are worsening despite treatment may benefit from reducing the use of sunscreens. (dermatologyadvisor.com)
  • Hair transplant should be considered in some cases of frontal fibrosing alopecia (FFA). (dermatologyadvisor.com)
  • Clinical characteristics, trichoscopy, histopathology and treatment outcomes of frontal fibrosing alopecia in an Asian population: A retro-prospective cohort study. (nih.gov)
  • Frontal fibrosing alopecia in Asians: a retrospective clinical study. (nih.gov)
  • Less common causes include primary hair shaft abnormalities (that is, the abnormality originates in the hair shaft), lichen planopilaris (lichen planus of the scalp) and frontal fibrosing alopecia, , and rare skin conditions. (msdmanuals.com)
  • They can be seen in the eyebrow in frontal fibrosing alopecia and sometimes in normal skin. (scarringalopecia.org)
  • This entity is also a possible overlapping condition, with features of lichen planopilaris and other alopecia types. (medscape.com)
  • What are the clinical features of lichen planopilaris? (dermnetnz.org)
  • Highlighting the main trichoscopic features of lichen planopilaris (LPP), Vañó-Galván, head of the trichology unit at Ramón y Cajal Hospital in Madrid, Spain, discussed the difference between active lesions and inactive lesions. (dermatologytimes.com)
  • Lichen planopilaris is an example of a primary lymphocytic folliculitis. (dermnetnz.org)
  • The hair follicles are the specific target of inflammation in primary cicatricial alopecias. (unboundmedicine.com)
  • This 2-part continuing medical education article will review primary cicatricial alopecias according to the working classification suggested by the North American Hair Research Society. (unboundmedicine.com)
  • The cause of the various cicatricial alopecias is poorly understood. (wikipedia.org)
  • However, all cicatricial alopecias involve inflammation directed at the upper part of the hair follicle where the stem cells and sebaceous gland (oil gland) are located. (wikipedia.org)
  • Cicatricial alopecias are not contagious. (wikipedia.org)
  • In general, cicatricial alopecias are not associated with other illnesses, and usually occur in otherwise healthy people. (wikipedia.org)
  • Cicatricial alopecias affect both men and women, most commonly adults, although all ages may be affected. (wikipedia.org)
  • Epidemiologic studies have not been performed to determine the incidence of cicatricial alopecias. (wikipedia.org)
  • Diagnosis and treatment of cicatricial alopecias is often challenging. (wikipedia.org)
  • Cicatricial alopecias are classified as primary or secondary. (wikipedia.org)
  • This discussion is confined to the primary cicatricial alopecias in which the hair follicle is the target of the destructive inflammatory process. (wikipedia.org)
  • In secondary cicatricial alopecias, destruction of the hair follicle is incidental to a non-follicle-directed process or external injury, such as severe infections, burns, radiation, tumors, or traction. (wikipedia.org)
  • Primary Scarring Alopecias (also known as cicatricial alopecias or scarring hair loss) are a group of conditions that destroy the hair follicle, replace it with scar tissue, and cause permanent hair loss. (alopecia.org.uk)
  • According to trigger factors, cicatricial alopecias are classified as primary cicatricial alopecia and secondary cicatricial alopecia . (alopeciacure.com)
  • How are cicatricial alopecias diagnosed? (alopeciacure.com)
  • Nonscarring alopecias tend to have preserved follicular ostia. (medscape.com)
  • Scarring alopecias have loss of follicular ostia, or atrophy. (medscape.com)
  • CCCA is a diagnostic category adopted by the North American Hair Research Society to encompass terms such as hot comb alopecia, follicular degeneration syndrome, pseudopelade in African Americans, and central elliptical pseudopelade in whites. (medscape.com)
  • 1 Clinically, the follicular features appeared identical to lichen planopilaris (LPP) however, the pattern of the disease was distinct from typical LPP in several ways. (skintherapyletter.com)
  • Alopecia mucinosa, also known as follicular mucinosis, is a condition resulting from the deposition of a jelly-like substance (called mucin) in and around the hair follicles. (darlinghairrestoration.com)
  • Perifollicular inflammation and follicular spongiosis in androgenetic alopecia. (musc.edu)
  • Lichen Planopilaris (believed to be a type of autoimmune disease) occurs more frequently in women than in men and more commonly in African-Americans than in Caucasians. (bernsteinmedical.com)
  • The caveat in transplanting patients whose scarring is the result of inflammatory disease processes (lichen planopilaris, discoid lupus erythematosus, etc), is to be certain that the disease process has "burned out" before undertaking the procedure. (shapiromedical.com)
  • Dendritic cells may help differentiate discoid lupus erythematosus alopecia from lichen planopilaris. (krakow.pl)
  • Discoid lupus (DLE) of the scalp is one of the scarring alopecias. (scarringalopecia.org)
  • Secondly, the condition resulted in a distinctive pattern of alopecia affecting the frontal hairline, associated with loss of eyebrows. (skintherapyletter.com)
  • This type of alopecia may present with unusual retention of the hairline (pseudo-fringe sign). (hairboutique.com)
  • You can recognize this type of alopecia by the thinning or complete loss of hair on the crown of the head or hairline starting to recede from the temples. (dslaboratories.eu)
  • This type of alopecia can also be caused by procedures such as face lifts which cause tension on the hairline. (dslaboratories.eu)
  • The pattern of the cicatricial alopecia is band-like, with erythema and papules around the follicles along the hairline. (mhmedical.com)
  • This article focuses on the alopecia types that are believed to be due to an inflammatory response with rapid secondary scarring if not controlled. (medscape.com)
  • It is a form of lichen planus , an inflammatory condition affecting the skin and mucous membranes. (rarediseases.org)
  • Lichen planopilaris is an uncommon inflammatory condition that can lead to permanent hair loss. (dermnetnz.org)
  • Lichen planus is a pruritic inflammatory dermatosis of unknown origin. (thedoctorsdoctor.com)
  • Conventional doctors are treating cicatricial alopecia with anti-inflammatory medications and topical corticosteroids. (alopeciacure.com)
  • Lichen planus (LP) is a chronic inflammatory disorder that most often affects middle-aged adults. (hindawi.com)
  • Lichen planus (LP) is a chronic inflammatory and immune mediated disease that affects the skin, nails, hair, and mucous membranes. (hindawi.com)
  • Platelet-rich plasma can be used as an adjunctive anti-inflammatory treatment for patients with lichen planopilaris. (dermatologyadvisor.com)
  • BACKGROUND AND OBJECTIVES: Lichen planus (LP) is a chronic inflammatory skin disease and is a major burden for affected patients. (bvsalud.org)
  • Making a diagnosis of lichen planopilaris clinically, trichoscopically , and with a scalp biopsy. (dermnetnz.org)
  • Lichen planus is frequently accompanied by clinically relevant systemic comorbidity. (bvsalud.org)
  • According to the American Academy of Dermatology Association (AAD), approximately 50 million men and 30 million women in the U.S. were estimated to have some form of alopecia in 2022. (prbulletin.com)
  • A scalp biopsy is essential for the diagnosis of cicatricial alopecia and is the necessary first step, as it can be hard to know the diagnosis for sure without a biopsy. (wikipedia.org)
  • New diagnostic techniques, such as trichoscopy may be used for non-invasive differential diagnosis of cicatricial alopecia. (wikipedia.org)
  • Making a diagnosis of cicatricial alopecia is always challenging. (alopeciacure.com)
  • A number of associated cutaneous findings have been reported in up to 15% of these patients including lichen planus-like eruptions (LP). (thedoctorsdoctor.com)
  • 16 Lichen planus affecting other sites (cutaneous, nail, mucosal) is seen more frequently in association with LPP (28-50%) 17,18 than with FFA (1.6-9.9%) 3,9,15 . (skintherapyletter.com)
  • Cutaneous lichen planus (CLP) most commonly involves the flexor surfaces of the extremities and presents as small itchy violaceous Papules in middle-aged adults. (hindawi.com)
  • Cutaneous lupus erythematosus Hair loss, also called alopecia, can occur on any part of the body. (msdmanuals.com)
  • Though there are many causes of hair loss, approximately 90% of the time, it is caused by the genetic condition Androgenetic Alopecia, more commonly known as Male Pattern Baldness and Female Pattern Baldness. (revivogen.com)
  • Findings of the scalp biopsy, including the type of inflammation present, location and amount of inflammation, and other changes in the scalp, are necessary to diagnose the type of cicatricial alopecia, to determine the degree of activity, and to select appropriate therapy. (wikipedia.org)
  • Lichen Planopilaris is a disease which attacks the mouth and skin and causes redness and inflammation of the skin. (dslaboratories.eu)
  • DLE is not considered a primary cicatricial alopecia, because the inflammation surrounds not only the hair follicle but many other structures in the skin. (darlinghairrestoration.com)
  • Facial lesions including papules, prominent veins, and lichen pigmentosus. (mhmedical.com)
  • Disorders that primarily affect the hair shaft (trichodystrophies) also are considered nonscarring alopecia. (msdmanuals.com)
  • Whether you're a dermatologist, primary care physician, PA, or NP, this unmatched guide provides everything you need to know about the most common disorders, including alopecia, psoriasis, and scalp and fungal nail infections, as well as more uncommon disorders. (callisto.ro)
  • Fibrosing alopecia in pattern distribution (FAPD): This also is a potential clinical variant of lichen planopilaris, with similar histologic features. (medscape.com)
  • Additionally, fibrosing alopecia in pattern distribution has some histologic/clinical overlap with androgenetic alopecia . (medscape.com)
  • Fibrosing alopecia in pattern distribution may also be an overlap of lichen planopilaris with androgenetic alopecia. (medscape.com)
  • Often referred to as 'Pattern' or 'Genetic' hair loss, androgenetic alopecia is the term for progressive hair loss. (ftgclinics.com)
  • Fibrosing alopecia in a pattern distribution (FAPD) and lichen planopilaris diffuse pattern (LPPDP) may be associated with scalp pruritis. (dermatologyadvisor.com)
  • A prescription drug called oral finasteride is available for males with androgenetic alopecia, also known as male pattern hair loss. (new-beauty.com)
  • What is the differential diagnosis for lichen planopilaris? (dermnetnz.org)
  • Recently described diffuse variants of lichenoid alopecias should be considered in the differential diagnosis of patients complaining of scalp pruritus. (dermatologyadvisor.com)
  • 648 It is considered to be a clinical variant of lichen planopilaris. (wikipedia.org)
  • Kossard S, Lee MS, Wilkinson B. Postmenopausal alopecia: a frontal variant of lichen planopilaris. (wikipedia.org)
  • Considered a clinical variant of lichen planopilaris (LPP), it has distinctive features and associations which distinguish it from LPP. (skintherapyletter.com)
  • In contrast, in androgenetic alopecia (AGA) or common baldness, one sees smaller, finer hairs (miniaturization) and non-inflamed, non-scarred scalp. (bernsteinmedical.com)
  • The diagnosis of lichen planopilaris (LPP) is confirmed by a combination of clinical and histologic features. (medscape.com)
  • Lichen planopilaris is suspected on the clinical presentation and careful examination of the mouth, nails, and skin for evidence of lichen planus elsewhere. (dermnetnz.org)
  • 2) Unfortunately, due to the variable clinical course of these processes, we cannot be certain that the disease will not reactivate at a later time.There are apparently no scientific studies that discuss survival rates of grafts in patients with various types of scarring alopecias. (shapiromedical.com)
  • It was originally named "lichen ruber planus" and "lichen psoriasis" [ 5 ]. (hindawi.com)
  • Lichen planopilaris (LPP) affects the scalp and hair. (rarediseases.org)
  • Lichen planopilaris usually affects young adult women, although the age range is wide and it can also affect men. (dermnetnz.org)
  • It affects both men and women and the number of people affected by alopecia increases every day. (dslaboratories.eu)
  • Technological advancements in alopecia treatment, increasing prevalence of hair loss, and rise in prevalence of chronic diseases associated with hair loss are major factors driving market revenue growth. (prbulletin.com)