• PMID
  • It includes LCTM1 which regulate the activity of serine/threonine phosphatase 2A (PP2A) through methylation of the C-terminal leucine residue of the catalytic subunit of PP2A [ PMID: 10600115 , PMID: 11697862 , PMID: 11060018 ]. (ebi.ac.uk)
  • Leucine aminopeptidase has been shown to be identical with prolyl aminopeptidase ( EC:3.4.11.5 ) in mammals [ PMID: 1908238 ]. (ebi.ac.uk)
  • aminopeptidase
  • Leucine aminopeptidase from Arabidopsis thaliana. (ebi.ac.uk)
  • Molecular structure of leucine aminopeptidase at 2.7-A resolution. (ebi.ac.uk)
  • xerB, an Escherichia coli gene required for plasmid ColE1 site-specific recombination, is identical to pepA, encoding aminopeptidase A, a protein with substantial similarity to bovine lens leucine aminopeptidase. (ebi.ac.uk)
  • Differentiation and identification of the two catalytic metal binding sites in bovine lens leucine aminopeptidase by x-ray crystallography. (ebi.ac.uk)
  • On the other hand, radiolabel was removed efficiently from DAT in the presence of leucine aminopeptidase , a nonspecific exo-type aminopeptidase. (thefreedictionary.com)
  • Additional isoenzyme markers are currently being sought, including leucine aminopeptidase (LAP), which has been resolved with the same buffers as MDH. (thefreedictionary.com)
  • regulates
  • Leucine is involved in another series of functions, such as metabolism of carbohydrates , facilitating the absorption of glucose by the cells, therefore it regulates the levels of blood sugar and it is suitable for diabetes . (botanical-online.com)
  • whey
  • The good news is that once you have the leucine taken care of (by utilising either approach above) the rice protein is every bit as good as whey. (exrx.net)
  • According to the label, 2.4 gram of the whey is leucine. (exrx.net)
  • That equates to the leucine in the whey being about 18 cents. (exrx.net)
  • motif
  • The structural modification includes addition or deletion of a leucine-based motif or parts thereof. (google.com)
  • 2. The modified botulinum neurotoxin type E of claim 1 , wherein the added leucine based motif is SEQ ID NO: 7, SEQ ID NO: 10 or SEQ ID NO: 12. (google.com)
  • A leucine-rich repeat (LRR) is a protein structural motif that forms an α/β horseshoe fold. (wikipedia.org)
  • The presence of the Leucine-Rich Repeat motif provides structural framework for protein-protein interactions. (wikipedia.org)
  • supplements
  • Although you can take supplements of leucine, it is recommended to meet the needs of this amino acid through a balanced diet . (botanical-online.com)
  • It may be worth mentioning however that Leucine-based supplements (as in, with the name 'leucine' on the bottle) are springing up across pretty much all brands, at least here in Aus. (bullshido.net)
  • Leucine supplements are used to help treat diabetes, muscle wasting, twitching and tremors, and liver and brain damage in alcoholics. (herbalremedies.com)
  • helices
  • Leucine transporter, like the neurotransmitter transporters in nerve cells, has a bundle of twelve alpha helices that form a transport channel through the membrane. (wikipedia.org)
  • localization
  • most recently, it has been demonstrated that sestrin 2 can directly bind to leucine and activate mTORC1 activity by promoting its localization to the lysosome. (wikipedia.org)
  • substrates
  • The concentration difference creates an electrochemical potential gradient that is used to catalyze the uptake of organic substrates (in this case leucine). (wikipedia.org)
  • acid
  • Leucine is an essential amino acid that the body cannot manufacture. (herbalremedies.com)
  • In healthy individuals, approximately 60% of dietary L-leucine is metabolized after several hours, with roughly 5% (2-10% range) of dietary L-leucine being converted to β-hydroxy β-methylbutyric acid (HMB). (wikipedia.org)
  • Other names in common use include leucyl-tRNA synthetase, leucyl-transfer ribonucleate synthetase, leucyl-transfer RNA synthetase, leucyl-transfer ribonucleic acid synthetase, leucine-tRNA synthetase, and leucine translase. (wikipedia.org)
  • Photo Leucine, as well as another photo-reactive amino acid derived from Methionine, Photo-Methionine, were first synthesized in 2005 by Monika Suchanek, Anna Radzikoska and Christoph Thiele from the Max Planck Institute of Molecular Cell Biology and Genetics with the objective of identifying protein to protein interaction throughout a simple western blot test that would provide high specificity. (wikipedia.org)
  • As mentioned in the introduction, L-Photo-Leucine is a synthetic derivative of the L- Leucine amino acid. (wikipedia.org)
  • L-Photo-Leucine is characterized by the presence of a diazirine ring linked to the R radical of the original amino acid. (wikipedia.org)
  • The rest of the amino acid has indeed the same structure as the original L-Leucine molecule, which includes, as every amino acid, an amino group and a carboxyl group bonded to an α-carbon, and a radical that is attached to this carbon atom. (wikipedia.org)
  • It is also important to mention that only the L- isomer of the photo-leucine amino acid is synthetized. (wikipedia.org)
  • The classic procedure for synthesizing photo-leucine is based on the following steps: 4,4'-azi-pentanoic acid, CCl4 and thionyl chloride are heated to 65 °C for 30 minutes. (wikipedia.org)
  • Compared to an average of human sequences, the internal composition is rich in Leucine, Glutamic Acid, and Lysine. (wikipedia.org)
  • astrocytes
  • Leucine is rapidly taken up into the brain where astrocytes convert it to alpha-ketoisocaproate via transamination of alpha-ketoglutarate to glutamate. (wikipedia.org)
  • significantly
  • The leucine group had significantly higher gains in total five-rep-max strength and individual-exercise five-rep-max strength in five out of the eight exercises. (anabolicminds.com)