Gamma glutamyl transferase (GGT) is an enzyme found in cell membranes of many tissues mainly in the liver, kidney, and pancreas. (medscape.com)
Objective: To compare clinicopathologic features of idiopathic IgA nephropathy in terms of serum gamma-glutamyl transferase (GGT) levels. (afsu.edu.tr)
Significant increases in the urinary excretion of albumin, retinol binding protein, beta 2 microglobulin, N-acetylglucosaminidase (NAG), alkaline phosphatase, gamma-glutamyl transferase and significant decreases in the renal reabsorption of calcium, urate, and phosphate were found in the exposed group compared with the referent group. (mcmaster.ca)
Results: Overall AUROC values for Age Platelet Index (API), Aspartate to Alanine Ratio (AAR), AST-to-Platelet Ratio Index (APRI), Fibrosis Index based on 4 Factors (FIB-4) and Gamma glutamyl transferase to Platelet Ratio Index (GPR) were 0.52, 0.49, 0.55, 0.55 and 0.54 respectively. (bvsalud.org)
The gamma-glutamyl transferase -to platelet ratio (GPR) was developed and investigated as available test that is useful in predicting liver fibrosis stages in chronic HBV patients. (bvsalud.org)
Impairment3
Increased risk in patients with renal impairment, including preterm neonates. (drugs.com)
In addition, coadministration with colchicine, fesoterodine and solifenacin is contraindicated in subjects with varying degrees of renal or hepatic impairment, and coadministration with eliglustat is contraindicated in subjects that are poor or intermediate metabolizers of CYP2D6 and in subjects taking strong or moderate CYP2D6 inhibitors. (guidelinecentral.com)
HIV infection and HAART is associated with low grade hepatotoxicity but no impairment of renal functions in the population studied. (ijbls.org)
Glutamyl3
Human gamma-glutamyltransferase catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. (wikipedia.org)
Human kidney gamma-glutamyl transpeptidase. (wikipedia.org)
The enzyme catalyzes the transfer of the gamma-glutamyl group from gamma-glutamyl peptides, such as glutathione to an acceptor such as peptides and L-amino acids. (medscape.com)
Liver and renal1
Alterations in liver and renal functions are among the complications of HIV infection, and highly active antiretroviral therapy (HAART) has been implicated. (ijbls.org)
Cholestasis3
Most common adverse drug reactions (≥5%) from clinical trials in pediatric patients were anemia, vomiting, increased gamma-glutamyltransferase, and cholestasis. (drugs.com)
Serum gamma glutamyltransferase (GGT) level in cholestasis of infancy is a complex issue. (hkjpaed.org)
Other causes of cholestasis of infancy with normal serum GGT, such as, Smith-Lemli-Opitz Syndrome, Arthrogryposis multiplex congenita, Renal dysfunction and Cholestasis (ARC) Syndrome are also mentioned. (hkjpaed.org)
Can Mean Platelet Volume Predicts Renal Outcome in Acute on Chronic Kidney Disease? (afsu.edu.tr)
Introduction: This study aimed to investigate the role of mean platelet volume (MPV) in predicting renal outcome in acute kidney injury (AKI) developing on pre-existing chronic kidney disease (CKD). (afsu.edu.tr)
However, excess myoglobin can occlude the renal filtration system leading to acute tubular necrosis and acute renal dysfunction. (passmed.uk)
Alanine aminotransferase1
Venkat and colleagues [ 1 ] described the clinical response to protocolized immunosuppression withdrawal in an ongoing multicenter study of 74 children who were more than 4 years post-transplantation, had normal alanine aminotransferase (ALT) and gamma-glutamyltransferase levels, and were receiving calcineurin inhibitor monotherapy. (medscape.com)
Complications1
Can we reduce renal and infectious complications through immunosuppressive withdrawal? (medscape.com)
Iron Defici1
Iron (non-heme) measurements are used in the diagnosis and treatment of diseases such as iron deficiency anemia, chronic renal disease, and hemochromatosis (a disease associated with widespread deposit in the tissues of two iron-containing pigments, hemosiderin and hemofuscin, and characterized by pigmentation of the skin). (cdc.gov)
Abnormal2
In addition, abnormal kidneys and ureteroliths can be palpated in some horses with chronic renal disease. (dvm360.com)
Detailed biochemical investigations of renal function were made on 75 male workers exposed to cadmium and an equal number of referents matched for age, sex, and employment status. (mcmaster.ca)
At admission, renal and liver biochemical profiles were unremarkable. (journalmc.org)
Kidney1
Renal cell carcinoma (RCC) is the most common type of kidney cancer in adults, accounting for more than 431,000 new cases and 179,000 deaths worldwide each year. (businesswire.com)
CALCIUM1
Calcium measurements are used in the diagnosis and treatment of parathyroid disease, bone diseases, chronic renal disease and tetany. (cdc.gov)
Pancreatic1
Gamma-glutamyltransferase: nucleotide sequence of the human pancreatic cDNA. (wikipedia.org)
Rats2
Rifampicin reduces nephrotoxicity of cyclosporine A in rats: studies of renal enzyme excretion. (ox.ac.uk)
Here, the aim of this work was to investigate the effect of g-radiation processing on the total phenolic and total flavonoids content of dried basil as well as to study the protective role of g-irradiated dried basil leaves against MTX-induced hepatic and renal toxicity in rats. (arccjournals.com)
Alterations1
patients presented several alterations in hematological, renal, hepatic, and inflammatory marker parameters, which offer a general overview of the state of health with which the patient with COVID-19 is admitted to the hospital. (bvsalud.org)
Metabolic1
BUN measurements are used in the diagnosis of certain renal and metabolic diseases. (cdc.gov)
Pancreatitis1
Hepatic cirrhosis, pancreatitis and renal pathology can also be reflected in GGT elevations. (irishequinecentre.ie)
Dose2
For patients on renal dialysis, an additional dose of [HA570 trade name] is recommended after each dialysis. (who.int)
Using cumulative exposure index and liver cadmium as estimates of dose, a two phase linear regression model was applied to identify an inflection point signifying a threshold level above which changes in renal function occur. (mcmaster.ca)
Diabetic2
Objective: We aimed at investigating the effect of non-albumin proteinuria on renal outcomes in patients with biopsy-proven diabetic nephropathy. (afsu.edu.tr)
Question 3 - A 78-year-old diabetic man undergoes renal function tests. (passmed.uk)
Severe1
The efficacy of methotrexate (MTX), a widely used cytotoxic chemotherapeutic agent, is often limited by severe hepatic and renal toxicity. (arccjournals.com)
Diagnosis2
The test is frequently requested in conjunction with the serum creatinine test for the differential diagnosis of prerenal, renal, and postrenal uremia. (cdc.gov)
Creatinine measurements are useful in the diagnosis and treatment of renal diseases. (cdc.gov)
Patients1
CheckMate -67T is a Phase 3 randomized, open-label trial evaluating subcutaneous administration of Opdivo co-formulated with Halozyme's proprietary recombinant human hyaluronidase, rHuPH20, or subcutaneous nivolumab (nivolumab and hyaluronidase) compared to intravenous (IV) Opdivo , in patients with advanced or metastatic clear cell renal cell carcinoma (ccRCC) who have received prior systemic therapy. (businesswire.com)
Injury1
It was concluded that basil can protect against MTX-induced hepatic and renal injury and may be of therapeutic potential in alleviating the systemic side effects of this chemotherapeutic agent. (arccjournals.com)
Function panel1
Renal function panel - The main test to check the health of your kidneys. (urgentmednetwork.com)
per-C, and was treated with renal replacement therapy for 6 weeks. (cdc.gov)
Volume2
Constataram-se aumentos significativos do índice de resistividade (IR) e da razão GGT:C urinária e evidências de aumento significativo do volume renal, 1,5 horas após a administração do contraste, somente no grupo que recebeu iohexol. (usp.br)
Glomerular filtration rate (GFR) is the volume of fluid filtered from the renal glomerular capillaries into the Bowman's capsule per unit time. (passmed.uk)
Effects1
The combined nephrotoxic and hepatotoxic effects of HAART were determined by assessing the renal and liver functions of HIV sero-positive subjects on HAART in a tertiary hospital. (ijbls.org)
Cell1
Clear cell renal carcinoma (ccRCC) is the most common form of RCC, affecting about 7 out of 10 people with RCC. (businesswire.com)