• The term precancerous or premalignant condition may refer to certain conditions, such as monoclonal gammopathy of unknown significance, or to certain lesions, such as colorectal adenoma (colon polyps), which have the potential to progress into cancer (see: Malignant transformation). (wikipedia.org)
  • Smoking is a risk factor for premalignant (as well as malignant) lung lesions. (wikipedia.org)
  • Other less-common conditions that also demonstrate an increased risk for malignant transformation include oral submucous fibrosis (OSF), xeroderma pigmentosum , dyskeratosis congenita, epidermolysis bullosa , iron deficiency, and late-stage syphilis . (medscape.com)
  • Actinic Keratoses (AK) - also known as Solar Keratoses, (AK, SK) is a common sun-induced, scaly or hypereratotic lesion, which has the potential to beome malignant. (skcin.org)
  • In this stage the lesion is either precancerous or already fully malignant. (nih.gov)
  • Radiologists who interpret a high volume of mammograms may not detect more cancers but are better at determining which suspicious lesions are not malignant, according to a new study. (sciencedaily.com)
  • Radiologists who interpret a high volume of mammograms may not detect more cancers but are better at determining which suspicious lesions are not malignant, according to a new study published online and in the April print edition of Radiology . (sciencedaily.com)
  • 1. Clinical and endoscopic predictors of gastric precancerous conditions: a large population case control study. (nih.gov)
  • 3. The role of endoscopic and demographic features in the diagnosis of gastric precancerous conditions. (nih.gov)
  • 11. Frequency of precancerous lesions in endoscopic gastric biopsies in chronic gastritis. (nih.gov)
  • Presence of gastric cancer or gastric precancerous conditions and lesions that require endoscopic surveillance or treatment. (who.int)
  • 8. Precancerous gastric conditions in high Helicobacter pylori prevalence areas: comparison between Eastern European (Lithuanian, Latvian) and Asian (Taiwanese) patients. (nih.gov)
  • The highest prevalence of lesions is found between the 5th and 6th decade of life. (bvsalud.org)
  • To assess the prevalence of oral precancerous lesions and conditions and to determine the potential risk factors associated among general population aged 20-70 years of Telangana region, Andhra Pradesh. (jiaphd.org)
  • Pathologically, precancerous tissue can range from benign neoplasias, which are tumors which don't invade neighboring normal tissues or spread to distant organs, to dysplasia, a collection of highly abnormal cells which, in some cases, has an increased risk of progressing to anaplasia and invasive cancer which is life-threatening. (wikipedia.org)
  • [ 1 ] The most common of these lesions is squamous dysplasia in association with leukoplakia and erythroplakia, which is the primary focus of this article. (medscape.com)
  • Precancerous conditions and epithelial dysplasia in the stomach. (nih.gov)
  • Dysplasia of the gastric mucosa and its relation to the precancerous state. (nih.gov)
  • Bronchial premalignant lesions can progress to squamous cell carcinoma of the lung. (wikipedia.org)
  • Premalignant lesions are morphologically atypical tissue which appear abnormal when viewed under the microscope, and which are more likely to progress to cancer than normal tissue. (wikipedia.org)
  • Hereditary conditions that are risk factors to cancer can also be risk factors to premalignant lesions. (wikipedia.org)
  • Increasing evidence suggests that the evasion of the immune system occurs in premalignant lesions, and that the nature of the first immune response to these lesions may determine if they progress to cancer or regress to normal tissue. (wikipedia.org)
  • She and her colleagues are investigating the potential role that genetic alterations may have in recognizing premalignant lesions of the breast. (nih.gov)
  • With the new device, which recently received FDA approval, health professionals can more easily inspect the oral cavity for cancer and its precursor lesions. (nih.gov)
  • that is, precursor lesions to prostatic carcinoma . (medscape.com)
  • Clinically, precancerous conditions encompass a variety of abnormal tissues with an increased risk of developing into cancer. (wikipedia.org)
  • Most often, these premalignant conditions manifest clinically as leukoplakia and erythroplakia. (medscape.com)
  • Clinically diagnosed as precancerous lesion or condition were subjected to punch (incisional biopsy) biopsy and evaluated histopathologically to confirm the diagnosis. (jiaphd.org)
  • Ichthyosis vulgaris is a skin condition where the skin's surface becomes dry, thick, and scaly. (medicalnewstoday.com)
  • Ultraviolet light damages the outer layer of the skin causing cells to overgrow and this produces the small red scaly lesions. (laserandskinclinics.co.uk)
  • Leukoplakia is defined by the World Health Organization as a white lesion of the oral mucosa that cannot be scraped off and cannot be attributed to another definable lesion (see the first image below). (medscape.com)
  • A white patch lesion found on a MUCOUS MEMBRANE that cannot be scraped off. (bvsalud.org)
  • Note the precise relationship between this jagged tooth and the lesion in the mucous membrane of the cheek. (nih.gov)
  • The aim of the present study was to evaluate the superiority of ME-NBI in the differential diagnosis of superficial gastric lesions identified with conventional WLE. (nih.gov)
  • ME-NBI achieved superior accuracy in the differential diagnosis of superficial gastric lesions identified with WLE. (nih.gov)
  • Some ASAP lesions mimic cancer, and in many instances, focal carcinoma may be present, but cytologic, histochemical, and architectural atypia are insufficient to establish a definitive diagnosis of cancer. (medscape.com)
  • Dr. Max Cutler:] Thus early diagnosis resulting in the elimination of precancerous conditions and in the cure of early cancer is by far the most important single factor in the curability of this disease. (nih.gov)
  • Unfortunately, the macroscopic appearance of pre-cancerous lesions can be difficult to distinguish from many benign conditions. (nih.gov)
  • Geographic tongue, also called benign migratory glossitis, is an inflammatory condition in which red patches appear on your tongue resembling continents on a globe. (ripondds.com)
  • The category ASAP includes a group of lesions (eg, adenosis, atypical adenomatous hyperplasia, intraductal hyperplasia, and acinar atypical hyperplasia) that have varying clinical significance. (medscape.com)
  • Effects of Maintenance on Quality of Performance of Cryotherapy Devices for Treatment of Precancerous Cervical Lesions. (medscape.com)
  • Cryotherapy is commonly used when a limited number of lesions exist. (skcin.org)
  • Cryotherapy means 'treatment using low temperature', and refers to the removal of skin lesions by freezing them. (skcin.org)
  • Premalignant squamous lesions of the oral cavity are areas of altered epithelium that are at an increased risk for progression to squamous cell carcinoma (SCC). (medscape.com)
  • Premalignant squamous lesions of the oral cavity most often occur on the buccal mucosa, the mandibular mucosa/sulcus, the palate, the tongue, and the floor of the mouth. (medscape.com)
  • Although the risk of an AK transforming into squamous cell carcinoma (SCC) is very low, the risk increases over time and with larger number of lesions. (skcin.org)
  • They are also called squamous cell carcinoma in situ or Intra-Epidermal Carcinoma's, which refers to the fact that the skin lesions are made up of early precancerous cells that are situated within the surface layers on the skin. (laserandskinclinics.co.uk)
  • The present study aimed to evaluate the influence of the IL1B - 31C/T polymorphism on gastric inflammatory response and precancerous lesions development - atrophic gastritis (AG) and intestinal metaplasia (IM) - in patients positive for Helicobacter pylori infection with functional dyspepsia (FD). (nih.gov)
  • Patients with superficial gastric lesions that were diagnosed by WLE as cancer or non-cancer with a slight suspicion of cancer were prospectively enrolled in the study. (nih.gov)
  • 10. Risk factors for progression to gastric neoplastic lesions in patients with atrophic gastritis. (nih.gov)
  • 16. Helicobacter pylori and precancerous conditions of the stomach: the frequency of infection in a cross-sectional study of 79 consecutive patients with chronic antral gastritis in Yaoundé, Cameroon. (nih.gov)
  • ASAP lesions have been identified in 0.5-23% of patients undergoing needle biopsies of the prostate. (medscape.com)
  • However, patients should be aware that there is a small risk of skin cancer development in a Bowens lesion, the risk is thought to be around 1 in 200 per year. (laserandskinclinics.co.uk)
  • Additional biopsies will be taken from any visible lesion or area with irregular mucosal surface pattern in endoscopy, suspicious of neoplasia. (who.int)
  • Pancreatic cancer primarily arises from microscopic precancerous lesions, such as pancreatic intraepithelial neoplasia (PanIN) and acinar-to-ductal metaplasia (ADM). (bvsalud.org)
  • Atrophic gastritis (AG) associated with Helicobacter pylori (HP) infection is a well-established cancer precursor lesion ( 7 ) in the cascade of distal gastric adenocarcinoma, as described by Correa ( 8 ). (iiarjournals.org)
  • ME-NBI was used to further characterize lesions picked up with WLE. (nih.gov)
  • Ichthyosis vulgaris is often called fish scale disease because the scales that characterize the condition look like fish scales. (medicalnewstoday.com)
  • Due to changes in hormones, pregnant women might be more susceptible to oral health conditions, like gingivitis, tooth decay, and pregnancy tumors. (changfamilydentalak.com)
  • A precancerous condition is a condition, tumor or lesion involving abnormal cells which are associated with an increased risk of developing into cancer. (wikipedia.org)
  • Some of the most common precancerous conditions include certain colon polyps, which can progress into colon cancer, monoclonal gammopathy of undetermined significance, which can progress into multiple myeloma or myelodysplastic syndrome. (wikipedia.org)
  • Some authorities also refer to hereditary genetic conditions which predispose to developing cancer, such as hereditary nonpolyposis colorectal cancer, as a precancerous condition, as individuals with these conditions have a much higher risk of developing cancer in certain organs. (wikipedia.org)
  • In most cases, many risk factors for precancerous conditions and lesions are the same risk factors that determines individuals vulnerable to a specific cancer. (wikipedia.org)
  • However, in many cases, precancerous conditions or lesions can be sporadic and idiopathic in nature, meaning that they are not associated with a hereditary genetic risk factor to the particular cancer, nor with a direct causative agent or other identifiable cause. (wikipedia.org)
  • The pathophysiology of precancerous lesions is thought to be similar to that of cancer, and also varies depending on the disease site and type of lesion. (wikipedia.org)
  • Anyone can develop skin cancer, but people with fair complexions are more susceptible to precancerous conditions and skin cancer than people with darker skin tones. (healthywomen.org)
  • We propose that integrated comparison of this information with other genome-wide data, such as mutational hotspots for specific genotoxins, tumour-specific mutation patterns and chromatin organisation and transcriptional activity in non-cancerous lesions (such as nevi), pre-cancerous conditions (such as polyps) and tumours, will improve our understanding of how environmental toxins lead to cancer. (nih.gov)
  • I'm a professor of oral medicine so my clinical work is treating diseases of the mouth, complications of cancer and cancer therapy, and early detection of oral precancerous and cancer lesions. (aadocr.org)
  • Background/Aim: Atrophic gastritis (AG) is the most important risk condition for gastric cancer (GC). (iiarjournals.org)
  • Treatment is directed at HPV-associated conditions such as pre-cancerous lesions, cancer or genital warts. (healthhub.sg)
  • Investigators at the Developmental Therapeutics Branch of the National Cancer Institute (NCI) have synthesized novel analogs of diphenylene iodonium (DPI) and di-thienyl-iodonium (DTI) as inhibitors of NOX and other flavin dehydrogenases for the treatment and prevention of cancer and inflammation-related conditions. (nih.gov)
  • All the progress that has been realized in the surgical and radiation treatment of cancer is of no avail unless the lesion is recognized early and treated correctly before it has become disseminated. (nih.gov)
  • We will now consider three forms of cancer which pass through definite precancerous stages and are, therefore, not only curable but preventable. (nih.gov)
  • An exam result is considered to be a false positive when further testing is recommended for a suspicious lesion but no cancer is found. (sciencedaily.com)
  • Oral cancer screenings check for any precancerous or cancerous conditions in the mouth. (ripondds.com)
  • Oral cancer screenings are vital to detect any precancerous or cancerous conditions in the mouth before they progress to an advanced stage of the disease. (smilesforlifedentistry.com)
  • The good news is that there are a number of simple ways to keep skin healthy, and there also are now many options available to treat skin conditions, if treatment is necessary. (healthywomen.org)
  • At Yankton Medical Clinic we offer treatment options for many different types of skin conditions such as those listed below. (nc2010.com)
  • PIN refers to the precancerous end of a morphologic spectrum involving cellular proliferation within prostatic ducts, ductules, and acini. (medscape.com)
  • Precancerous conditions of the skin or oral cavity can appear as visible lesions without associated pain or discomfort, while precancerous conditions of the hematological system are typically asymptomatic, and in the case of monoclonal gammopathy of unknown significance, it may only rarely cause numbness and tingling in the hands and feet or difficulty with balance (see: peripheral neuropathy). (wikipedia.org)
  • Ichthyosis vulgaris is the most common form of ichthyosis, a group of skin conditions. (medicalnewstoday.com)
  • Ichthyosis vulgaris is a type of ichthyosis, a group of related skin conditions that interfere with the skin's ability to shed dead skin cells, causing extremely dry, thick skin. (medicalnewstoday.com)
  • A doctor diagnoses the condition by looking at the skin changes and determining if anyone else in the family has a similar problem. (medicalnewstoday.com)
  • A newborn with the condition will have thick plates of skin that crack and split apart. (medicalnewstoday.com)
  • Ichthyosis vulgaris is also commonly associated with other skin conditions. (medicalnewstoday.com)
  • They are extremely common lesions, especially on the sun-exposed skin of fair-skinned people. (skcin.org)
  • There are many times the number of invisible (subclinical) lesions as visible ones on the skin surface. (skcin.org)
  • Skin conditions can affect anyone-young and old, men and women. (healthywomen.org)
  • Skin problems can be difficult to diagnose because many skin conditions share similar symptoms. (healthywomen.org)
  • Primary care physicians are able to evaluate many skin conditions. (healthywomen.org)
  • There are a variety of skin conditions that can cause a person concern. (nc2010.com)
  • Ultraviolet light is also responsible for producing premature ageing, wrinkles, flat brown pigmented skin lesions ("sun spots"), and skin cancers. (laserandskinclinics.co.uk)
  • It works by destroying abnormal skin cells and causes a pronounced inflammation in skin lesions. (laserandskinclinics.co.uk)
  • It is relatively painful but very effective (90% of skin lesions will resolve with a single freeze). (laserandskinclinics.co.uk)
  • Studies have shown that avoidance of further exposure to sunlight reduces the number of new skin lesions. (laserandskinclinics.co.uk)
  • The severity of chronic inflammation and inflammatory activity, as well as the presence of precancerous lesions were evaluated accordingly to the updated Sydney System. (nih.gov)
  • Associated lesions, such as necrosis and inflammation, should be diagnosed separately. (nih.gov)
  • In susceptible individuals, it is probable that infinitesimal amounts of the stimulating chemical agent can result in this condition. (nih.gov)
  • Leukoplakic lesions related to abnormal keratin fiber formation. (bvsalud.org)
  • Some medical conditions can contribute to tooth loss. (ripondds.com)
  • Ichthyosis is a relatively common condition, impacting approximately 1 in every 250 people . (medicalnewstoday.com)
  • This lesion is ten times as common in men as in women. (nih.gov)
  • Glandular stomach lesions are quite rare in NTP mouse studies. (nih.gov)
  • Reversibility of catechol-induced rat glandular stomach lesions. (nih.gov)
  • Altered patterns of mucin secretion in the precancerous lesions induced in the glandular part of the rat stomach by the carcinogen N-methyl-N-nitrosoguanidine. (nih.gov)
  • 14. [Precancerous conditions and lesions of the stomach]. (nih.gov)
  • We assess your situation and condition to decide which outpatient geriatric services are right for you or a senior Veteran in your care, and then we coordinate your care. (va.gov)
  • Osteoporosis is a condition that occurs when we absorb more bone than we replace, resulting in weakened bones. (changfamilydentalak.com)
  • We observed a trend toward a significantly higher number of precancerous lesions in the following order: normal findings, hyperechoic foci/stranding without lobularity, and hyperechoic foci/stranding with lobularity. (bvsalud.org)
  • 5. Gastric precancerous lesions among Nigerians with chronic gastritis. (nih.gov)
  • Certain congenital genetic conditions can result in teeth which never develop. (ripondds.com)
  • In rare instances, adults can acquire the condition as a side effect of certain medications or other medical conditions. (medicalnewstoday.com)
  • A combination of factors is usually responsible for this type of lesion. (nih.gov)