Visceral leishmaniasis: what are the needs for diagnosis, treatment comparison with 30-day sodium stibogluconate monotherapy. (cdc.gov)
ne-mesh impregnated bednets against visceral leishmaniasis in [cited 2008 Feb 9]. (cdc.gov)
Leishmaniasis has 2 major forms: cutaneous, characterized by skin sores, and visceral, which affects internal organs and is characterized by high fever, substantial weight loss, swelling of the spleen and liver, and anemia. (cdc.gov)
Visceral leishmaniasis is also called kala-azar, a Hindi term meaning "black fever. (cdc.gov)
The project will run for three years and aims to test new treatments for kala-azar (visceral leishmaniasis, or VL) and co-infection of the disease with HIV in Ethiopia and Sudan. (dndi.org)
The AfricoLeish project, 'Care Package for Treatment and Control of Visceral Leishmaniasis in East Africa', aims to develop and deliver a shorter combination treatment for kala-azar patients that is equally as safe and effective as the current WHO-recommended first-line treatment for the disease (SSG&PM, sodium stibogluconate and paromomycin) in East Africa. (dndi.org)
Currently we have a portfolio of discovery projects in various stages of development in African sleeping sickness and visceral leishmaniasis," commented the university's Professor Mike Ferguson. (pharmatimes.com)
Results The barriers along the visceral leishmaniasis (VL) supply chain were identified as emerging themes, grouped across supply chain activities and health systems component(s). (bmj.com)
As of now the most common Neglected Tropical Diseases in India are Lymphatic Filariasis, Visceral Leishmaniasis, Rabies, Leptospirosis, Dengue, and Soil-Transmitted Helminthic Infections (STH). (clearias.com)
My research interests lie within modelling and decision analysis for vector-borne infections - in particular human African trypanosomiasis and visceral leishmaniasis. (ntdmodelling.org)
Leishmaniasis is a collection of diseases caused by more than 20 Leishmania parasite species that manifest as either visceral, cutaneous, or mucocutaneous leishmaniasis. (bvsalud.org)
Here, we report on the continued optimization of a series of imidazopyridines for visceral leishmaniasis and a scaffold hop to a series of substituted 2-(pyridin-2-yl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazoles with improved absorption, distribution, metabolism, and elimination properties. (bvsalud.org)
The Roll Back Malaria Programme, for example, emphasizes the use of insecticide treated bednets in Africa and targets a 30-fold increase in treated bednet use by 2007. (who.int)
WHO), four parasitic diseases--malaria, Malaria remains one of the most serious schistosomiasis, leishmaniasis and trypa- public health problems in the world. (who.int)
Eisai is proactively collaborating with academia and research organizations and has participated in 11 joint research projects to develop new medicines and vaccines for malaria, Chagas disease, leishmaniasis, and filariasis, with the support of the GHIT Fund. (eisai.com)
Earlier this year, I attended a workshop in Arusha, Tanzania to train research scientists from South Africa, Ivory Coast, Mauritania, Botswana, Kenya and Tanzania on how to use products derived from NASA satellites to monitor climate and environmental factors that influence the transmission of vector-borne diseases such as malaria, leishmaniasis, trypanosomiasis, schistosomiasis and Rift Valley Fever. (nasa.gov)
In 2015, 91 countries and areas had ongoing malaria transmission, but 90% of malaria cases and 92% of malaria deaths occurred in Sub-Saharan Africa, says the WHO . (acs.org)
Malaria is a mosquito-borne disease affecting millions of people mainly in Sub-Saharan Africa, Asia and some South American countries. (unl.pt)
The use of the primary school platform to treat millions of children for schistosomiasis and helminthiasis in Africa is a perfect example. (disabled-world.com)
dried DAT, rK39 strip test and KAtex in East Africa and the Indian subcontinent. (cdc.gov)
'While we have managed to deliver a new first-line treatment for kala-azar in East Africa, sodium stibogluconate combined with paromomycin, SSG&PM, we need to continue searching for shorter, safer treatments ', said Dr Monique Wasunna, Head of DND i Africa and one of the four principal investigators of the AfriCoLeish project. (dndi.org)
The dissemination of AfriCoLeish project results will facilitate uptake of new treatments for kala-azar and for co-infection of kala-azar with HIV in East Africa, and will provide support to national programmes in the adoption of the new treatments. (dndi.org)
The improved treatment options will allow patients in East Africa to benefit from safe, cost-effective, and shorter treatments, while also reducing the treatment costs for health providers. (dndi.org)
Together, these diseases represent a scourge to both humans and animals in the region, affecting millions in East Africa alone. (nasa.gov)
It presents information about african trypanosomiasis, professional information, travel information, fact sheet about the diseases in East Africa and West Africa. (bvs.br)
Leishmania4
Increasing risk factors for leishmaniasis include urbanization, extended agricul- tural projects and civil unrest and the increase in patients with Leishmania infantum and HIV co-infection in the Region may signal a new threat. (who.int)
Neglected parasitic diseases (NPD) include some of the worst human infections and are caused by pathogens including T. brucei (human African trypanosomiasis or sleeping sickness), T. cruzi (American trypanosomiasis or Chagas disease), Leishmania spp (leishmaniasis), which cause large disease burdens, as well as high mortality and morbidity rates in afflicted countries. (gla.ac.uk)
Diseases7
Tropical diseases lacking adequate control measures: den- sis in eastern Africa: current status. (cdc.gov)
Neglected diseases are a diverse group of communicable diseases in roughly 150 countries, mainly in Africa, Asia, Latin America and the Caribbean, which affect more than 1 billion people and cost developing economies billions of dollars every year. (iam-media.com)
The DDU will work with GSK's Kinetoplastids Discovery Performance Unit at the company's Tres Cantos Medicines Development Campus in Spain, pursuing an integrated, multidisciplinary effort to find effective treatments for three neglected tropical diseases (NTDs), Chagas disease, leishmaniasis and African sleeping sickness. (pharmatimes.com)
The Drug Discovery Unit at Dundee University was set up in 2005 specifically to fill a void in research and development of drug targets for diseases of poverty such as leishmaniasis, Chagas disease and sleeping sickness (human African trypanosomiasis/HAT). (pharmatimes.com)
Objectives To understand stakeholders' perceptions of the access barriers to quality-assured diagnostics and medicines for leishmaniasis in the high-burden region of eastern Africa, and to identify key bottlenecks to improve the supply of commodities for neglected tropical diseases. (bmj.com)
Neglected Tropical Diseases are prevalent in marginalized countries of Asia, Africa, and the Americas. (clearias.com)
These diseases affect the world's poorest people living in remote and rural areas of low-income countries in Sub-Saharan Africa. (sciencepg.com)
Chagas Disease2
Sanofi-aventis has agreed to renew its support for the WHO program to eliminate sleeping sickness, and its support for Buruli ulcer, Chagas disease and leishmaniasis for the next five years. (disabled-world.com)
This continued support will ensure that necessary resources will be available also to move forward in combating leishmaniasis, Buruli ulcer and Chagas disease. (disabled-world.com)
Sleeping Sickness4
African trypanosomiasis, also known as African sleeping sickness or simply sleeping sickness, is an insect-borne parasitic infection of humans and other animals. (wikipedia.org)
According to the Dundee researchers, "significant progress" has been made at the university over the last five years towards developing a new treatment for African sleeping sickness in particular. (pharmatimes.com)
Sanofi, a pharmaceutical company is going to provide support to WHO's for its global program for the elimination of Human African trypanosomiasis - Sleeping sickness and Leishmaniasis. (clearias.com)
It presents informations about African sleeping sickness, also known as African trypanosomiasis, and it impact, symptoms and statistics. (bvs.br)
Lymphatic filariasis1
GlaxoSmithKline announced a new five year commitment to expand their donation of albendazole through WHO, in addition to their current donation for lymphatic filariasis to treat school-age children for soil transmitted helminthiases in Africa. (disabled-world.com)
Human taeniasis (HTT) and human cysticercosis (HCC) age-prevalence data from 16 studies in Latin America, Africa and Asia were extracted through a systematic review. (imperial.ac.uk)
In 2021, approximately 800 combined cases were reported to the WHO, with over 90% caused by T. b. gambiense (see WHO: Human African trypanosomiasis ). (msdmanuals.com)
Kala-azar1
Through a randomized clinical trial in Eastern Africa, the project will, for the first time, provide conclusive evidence-based data on the WHO recommendation to treat kala-azar/HIV co-infected patients using Ambisome 40 mg/kg total dose, and on the locally used regimen of AmBisome 30mg/kg in combination with miltefosine that is used by MSF in Ethiopia. (dndi.org)
Hemolymphatic1
African trypanosomiasis symptoms occur in two stages: the hemolymphatic stage and the neurological stage (the latter being characterised by parasitic invasion of the central nervous system). (wikipedia.org)
Treatments1
There have also been "promising results" in identifying potential treatments for leishmaniasis. (pharmatimes.com)
Prevention1
It presents travel information about trypanosomiasis and it description, occurrence, risk of travelers, clinical presentation, prevention and treatment. (bvs.br)
Most of these deaths are in African children but many are in nonimmune adults. (the-medical-dictionary.com)
Countries2
The disease occurs regularly in some regions of sub-Saharan Africa with the population at risk being about 70 million in 36 countries. (wikipedia.org)
Three major outbreaks have occurred in recent history: one from 1896 to 1906 primarily in Uganda and the Congo Basin, and two in 1920 and 1970, in several African countries. (wikipedia.org)
Control1
Trypanosomiases and Leishmaniases Control Unit. (who.int)
Region2
Concerns have been expressed about the view point of WHO AFRO concerning research for health in the African Region. (bvsalud.org)
WHO AFRO considers research a critical component in the improvement of health in the Africa region. (bvsalud.org)
Research1
This article investigates the claim that decolonisation is an appropriate and legitimate value in the process of current-day biomedical research, particularly in Africa. (bvsalud.org)
Cases1
Estimates suggest 30,000 new cases per year in Africa, with numbers rising sharply during an epidemic. (dndi.org)
Tropical1
Despite the significant mortality and morbidity associated with leishmaniasis, it remains a neglected tropical disease. (bvsalud.org)
Specific1
Conclusions Addressing supply barriers in eastern Africa requires consistent, specific efforts at the global and national levels, progressing from current partnerships and agreements. (bmj.com)