AnatomyOrganismsDiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentPhenomena and ProcessesDisciplines and OccupationsAnthropology, Education, Sociology and Social PhenomenaInformation ScienceHealth Care
Heart FailureHeartVentricular Function, LeftVentricular FunctionHeart VentriclesPhenylisopropyladenosineRubidium RadioisotopesMyocardiumVentricular Dysfunction, LeftStroke VolumeHeart RateVentricular Function, RightEchocardiographyGuinea PigsMyocytes, CardiacMyocardial ContractionCardiac Output, LowHemodynamicsMyocardial InfarctionCardiac OutputHeart DiseasesCardiomyopathy, DilatedVentricular RemodelingSystoleHeart Function TestsCardiac Pacing, ArtificialHeart Failure, SystolicTime FactorsCardiomyopathiesDiastoleHeart Septal Defects, VentricularTreatment OutcomeElectrocardiographyCardiotonic AgentsHeart TransplantationNatriuretic Peptide, BrainHeart Failure, DiastolicArrhythmias, CardiacCardiomegalyVentricular Dysfunction, RightFollow-Up StudiesProspective StudiesCardiac CatheterizationAdrenergic beta-AntagonistsMyocardial IschemiaEchocardiography, DopplerCardiac Surgical ProceduresHeart Defects, CongenitalChronic DiseaseHypertrophy, Left VentricularExercise TestDeath, Sudden, CardiacRadionuclide VentriculographyVentricular PressureDogsBlood PressureCardiac VolumeHeart AtriaCoronary DiseasePrognosisVentricular DysfunctionPredictive Value of TestsTreatment FailureDisease Models, AnimalCoronary CirculationGated Blood-Pool ImagingRisk FactorsHeart-Assist DevicesRadionuclide AngiographyAngiotensin-Converting Enzyme InhibitorsRetrospective StudiesPropanolaminesSeverity of Illness IndexBiological MarkersDobutamineExercise TolerancePacemaker, ArtificialOxygen ConsumptionAtrial Natriuretic FactorFetal HeartFibrosisMyocarditisMitral Valve InsufficiencyDiureticsHeart ValvesMyocardial Reperfusion InjuryCardiac Resynchronization TherapyMagnetic Resonance Imaging, CineHeart BlockMetoprololRisk AssessmentCardiovascular AgentsEchocardiography, Doppler, PulsedAtrial Function, LeftCoronary Artery BypassEchocardiography, Doppler, ColorHospitalizationAtrial FibrillationPulmonary Wedge PressureCarbazoles
Resynchronization therapyArrhythmiaVentricleAtrial fibrillationArrhythmiasSymptomsPulmonaryPacemakerCongestiveCatheterizationDysfunctionSevereRenalHypertrophyMortalityShortness of breTachycardiaEchocardiographySudden cardiNormal ventricularFibrillationClinicalDiastolic pressureComplicationsTherapyAcuteReduced left ventricuImpairmentSurgicalPediatricHypertensionContractilityHeart'sInterventricular septumMyocardial oxygenAbnormalInsufficiencyBundle brancSymptomatic patientsRhythmAbstractCardiopulmonaryRespiratoryCardiovascularPerioperativeEndocardialEjection timeStroke volumeCoronary sinusVelocityPacingSeptumChronicSurvivalAtrioventricularSystoleCardiomyopathyLBBBUndergoing cardiac surgeryPhysiologyReductionAssessmentImplantableMyocardiumSignificantly
Resynchronization therapy19
Arrhythmia12
  • Our center reach the same level as other topnotch cardiovascular medical centers worldwide in the treatments of hypertension, hyperlipidemia, arrhythmia (electrophysiologic study, catheter ablation for cardiac arrhythmia, radiofrequent catheter ablation, heart pacemaker, implantable cardioverter defibrillator) and heart failure. (cmuh.org.tw)
  • AFib is the most common sustained heart arrhythmia. (pontevedrarecorder.com)
  • The usual initial dose of Sectral to treat ventricular arrhythmia is 400 mg daily given as 200 mg twice daily. (rxlist.com)
  • An ICD constantly keeps track of your heart rhythm and sends a small shock to the heart muscle if the rhythm becomes abnormal (arrhythmia). (clevelandclinic.org)
  • Patients with cardiac tumors can be asymptomatic or may present with arrhythmia, heart failure, or sudden death. (sts.org)
  • The risk of cardiac arrhythmia increases with age, with the following forms being potentially life threatening: ventricular tachycardia, ventricular fibrillation, and atrial fibrillation. (bumrungrad.com)
  • Atrial fibrillation is a supraventricular arrhythmia that adversely affects cardiac function and increases the risk of stroke. (aafp.org)
  • Atrial fibrillation is a supraventricular arrhythmia characterized by uncoordinated electrical activation of the atria and an irregular, often rapid, ventricular response causing hemodynamic compromise. (aafp.org)
  • What Are The Symptoms Of Problematic (Arrhythmia) Heart Rhythm? (phdsc.org)
  • Objective Spinal cord injury (SCI) can lead to significant cardiac arrhythmia. (go.jp)
  • Patients who experienced arrhythmia during HD had higher left ventricular mass and left ventricular mass index, lower post-dialysis K+ level, higher QTc and QTdc both before and after HD. (who.int)
  • ST-segment depression was significantly related to ventricular arrhythmia. (who.int)
Ventricle29
  • The left ventricle enlarges and the ejection fraction is reduced. (justia.com)
  • More recently, PAB has played a role in the preparation and "training" of the left ventricle (LV) in patients with dextro-transposition of the great arteries (d-TGA) who are evaluated for a delayed arterial switch procedure. (medscape.com)
  • A reduction of PBF also decreases the total blood volume returning to the LV (or the systemic ventricle) and often improves ventricular function. (medscape.com)
  • It targets the motor proteins that cause muscle contraction and prolongs the action of the left ventricle of the heart, which pumps blood around the body. (pharmatimes.com)
  • The Phase II trial compared the intravenously-administered drug to placebo in 45 heart failure patients with impaired function of the left ventricle, who were also taking background therapy with ACE inhibitors and beta blockers. (pharmatimes.com)
  • Heart failure with normal left ventricular ejection fraction (HFNEF) is a clinical entity that embodies symptoms of heart failure in the presence of preserved systolic function of the left ventricle. (ersjournals.com)
  • in Japan.1 The Japanese word "takotsubo" translates to "octopus pot" describing the shape of the left ventricle during systole. (jefferson.edu)
  • It is placed in a blood vessel near your heart to keep track of pressure in the blood vessel and the left ventricle. (clevelandclinic.org)
  • It is described as a depression of the contractile function of the mid and apical segments of the left ventricle with compensatory hyperkinesis of the basal walls. (racgp.org.au)
  • The dilatation of the left ventricle frequently induces intracardiac conduction delays resulting in asynchronous left ventricular motion. (biomedcentral.com)
  • The right ventricle contracts during left ventricular end-diastole, leading to a "bulging" of the septum into the left ventricle. (biomedcentral.com)
  • Resynchronization of the intraventricular conduction can be achieved by introducing an additional lead through the coronary venous sinus to stimulate the left ventricle (biventricular pacing, BVP). (biomedcentral.com)
  • Physicians settled on the right ventricle as the preferred site for lead placement early in the history of the pacemaker. (medtechdive.com)
  • The lead received premarket approval from the FDA 15 years ago but had a label that limited its use to pacing of the right ventricle or atrium. (medtechdive.com)
  • Last year, a clinical trial of 52 heart failure patients linked His bundle pacing to larger, more consistent improvements in left ventricle function than are typically achieved by right ventricle pacing. (medtechdive.com)
  • In SVR, surgeons cut open the left ventricle and sew it back together - without actually removing any tissue - to more closely resemble a smaller, normally shaped heart. (hopkinsmedicine.org)
  • However, conventional CRT devices use wired leads to deliver pacing pulses to the left ventricle. (meddeviceonline.com)
  • The WiSE Technology is leadless, completely eliminating the need for a pacing wire in the left ventricle. (meddeviceonline.com)
  • Data suggests this is largely due to limitations on where current, market-approved leads can be placed in the heart's venous anatomy to stimulate the left ventricle. (meddeviceonline.com)
  • EBR Systems' WiSE Technology consists of a tiny electrode implanted in the left ventricle. (meddeviceonline.com)
  • This unique technology eliminates the need for a left ventricular lead and is designed to let the physician place the stimulation point at an optimal, patient specific location inside the left ventricle (endocardially) which may potentially be more effective. (meddeviceonline.com)
  • The Company's initial product eliminates the need for coronary sinus leads to stimulate the left ventricle in heart failure patients requiring CRT. (meddeviceonline.com)
  • Nonetheless, a recent review has highlighted the disconnect between Doppler echo measurements and true diastolic properties of the left ventricle, and has questioned the prevailing assumption that HF with preserved systolic function is always caused by diastolic dysfunction. (bmj.com)
  • Basically the right and left ventricle are designed to contract at the same time. (blogspot.com)
  • There is also asynchrony within the left ventricle apart from that of the septum and lateral wall being out of sync. (blogspot.com)
  • Various segments of the Left ventricle also do not contract as an organized system , some segments contracting and relaxing out of tune with others.This is referred to as intra-ventricular dysynchrony. (blogspot.com)
  • The EF does not tell the whole story as there is also impaired filling of the left ventricle.So not only is the stroke volume diminished by a lower EF but impaired filling leads to less blood to eject.Cardiac output falls and is particularly evident during exercise. (blogspot.com)
  • Effect of isolated left bundle branch block on systolic and diastolic function of left ventricle), see ref 3 below. (blogspot.com)
  • Coronary sinus, normally located between the LEFT ATRIUM and LEFT VENTRICLE on the posterior surface of the heart, can serve as an anatomical reference for cardiac procedures. (bvsalud.org)
Atrial fibrillation13
Arrhythmias4
  • Fatal or life-threatening cardiomyopathy and ventricular arrhythmias were reported. (nih.gov)
  • Sectral (acebutolol HCl) is a selective, hydrophilic beta-adrenoreceptor blocking agent with mild intrinsic sympathomimetic activity for use in treating patients with hypertension and ventricular arrhythmias . (rxlist.com)
  • Patients with heart failure are about 6 to 9 times more likely than the general population to have ventricular arrhythmias that can lead to SCA. (clevelandclinic.org)
  • Fibromas are more often resected because they do not regress and have a strong association with ventricular arrhythmias. (sts.org)
Symptoms21
  • We need to see whether the improvements in cardiac function translate into real benefits for patients, in terms of their symptoms and quality of life, and whether it can impact on mortality and morbidity. (pharmatimes.com)
  • this is an important endpoint for these patients, in whom rapid worsening of the disease can lead to worse symptoms and life-threatening situations. (prnewswire.com)
  • CRT alleviates symptoms, such as breathlessness and fatigue, and reduces mortality, yet 30-40% of patients do not improve (non-responders). (escardio.org)
  • This irregularity in the pulse often results in symptoms of palpitations, fatigue, breathlessness and even reduced cardiac function (i.e., congestive heart failure). (pontevedrarecorder.com)
  • Symptoms of heart failure include labored breathing, fluid accumulation (especially in the legs) and fatigue. (lahey.org)
  • LANOXIN increases left ventricular ejection fraction and improves heart failure symptoms as evidenced by improved exercise capacity and decreased heart failure-related hospitalizations and emergency care, while having no effect on mortality. (guidelinecentral.com)
  • ASV effectively attenuates CSR in patients with HFNEF and improves heart failure symptoms and cardiac function. (ersjournals.com)
  • Takotsubo cardiomyopathy (TC), also known as stress cardiomyopathy, and broken heart syndrome is characterized by transient left ventricular (LV) apical akinesis with symptoms mimicking acute coronary syndrome. (jefferson.edu)
  • About 75% of patients who do not get relief from symptoms with medication and have CRT, with or without an ICD, have improvement in their symptoms. (clevelandclinic.org)
  • Recent studies have shown an acute and sustained hemodynamic improvement, reversal of LV-remodeling, an increased quality of life, a reduction of symptoms of heart failure, and improvement of exercise tolerance after biventricular pacing. (biomedcentral.com)
  • Symptoms and cardiac function improved significantly in patients who discontinued methamphetamine use. (acc.org)
  • Due to the chance to recover cardiac function and symptoms at an early stage of the disease, early detection of heart problems in patients with methamphetamine abuse could prevent further deterioration of the cardiomyopathy. (acc.org)
  • There are some symptoms that can indicate the failure of the heart. (phdsc.org)
  • These symptoms include chest pain, fainting, or severe weakness because of the improper flow of blood by the heart, irregular heartbeat of the heart which can also cause shortness of breath. (phdsc.org)
  • When such symptoms occur one must visit the doctor who can give the correct treatment to the patient. (phdsc.org)
  • Although, the patient still needs medicines all throughout his life to subside the symptoms of the disease. (phdsc.org)
  • Studies have demonstrated successful CRT therapy reduces heart failure symptoms, hospitalizations and mortality. (meddeviceonline.com)
  • These patients present with exertional dyspnoea in the context of normal systolic function, and in this situation, symptoms may be ascribed to diastolic HF. (bmj.com)
  • Determine which clinical assessments and tests are needed for a patient with cardiovascular symptoms. (cdc.gov)
  • Today I'll present an overview of post-COVID conditions as an introduction of the main presentation on evaluating and supporting patients with cardiovascular symptoms and complications following COVID-19. (cdc.gov)
  • Even those patients who were presumed by a clinician to have COVID can present with lingering symptoms. (cdc.gov)
Pulmonary23
  • Although a recent joint society scientific statement (the American Association of Cardiovascular Pulmonary Rehabilitation, the American Heart Association, and the American College of Cardiology) suggests home-based cardiac rehab (CR) is appropriate for low- and moderate-risk patients, there are no paradigms to define such individuals with coronary heart disease. (journaltocs.ac.uk)
  • The resulting increase in pulmonary venous pressure and reduction in cardiac output cause congestive heart failure. (justia.com)
  • Pulmonary artery banding (PAB) is a technique of palliative surgical therapy used by congenital heart surgeons as a staged approach for operative correction of congenital heart defects. (medscape.com)
  • This technique was widely used in the past as an initial surgical intervention for infants born with cardiac defects characterized by left-to-right shunting and pulmonary overcirculation. (medscape.com)
  • [ 1 ] In this report, Muller and Danimann described palliation by the "creation of pulmonary stenosis" in a 5-month-old infant who had a large ventricular septal defect (VSD) and pulmonary overcirculation. (medscape.com)
  • Congenital heart defects with left-to-right shunting and unrestricted pulmonary blood flow (PBF) due to a drop in pulmonary vascular resistance result in pulmonary overcirculation. (medscape.com)
  • In the acute setting, this leads to pulmonary edema and congestive heart failure in the neonate. (medscape.com)
  • Within the first year of life, this unrestricted flow and pressure can lead to medial hypertrophy of the pulmonary arterioles and fixed pulmonary hypertension. (medscape.com)
  • PAB may not be tolerated in patients who have cardiac defects that depend on mixing of the systemic and pulmonary venous blood to maintain adequate systemic oxygen saturations. (medscape.com)
  • Patients who are selected for pulmonary artery banding (PAB) and staged cardiac repair are determined based on the experience and training of the pediatric cardiologists and congenital heart surgeons at any given institution. (medscape.com)
  • We established a thrombolytic emergency team which provides a timely thrombolytic therapy for patients with acute peripheral arterial occlusive disease (PAOD), acute pulmonary embolism and acute deep vein thrombosis (DVT). (cmuh.org.tw)
  • Based on these findings, we diagnosed the patient as a case of MM. Echocardiography revealed right heart enlargement, pulmonary hypertension, left ventricular hypertrophy, and thickening of the main pulmonary artery and its branches. (biomedcentral.com)
  • Eisenmenger's syndrome (ES) is a rare complication of congenital heart disease that includes pulmonary artery hypertension and reversed or bidirectional shunts. (wjgnet.com)
  • The main pathophysiological correlate is impaired left ventricular filling, resulting in diastolic dysfunction with increased end-diastolic left ventricular pressure ( P LV,ED ), with consequent pulmonary congestion, increased stimulation of pulmonary vagal irritant receptors (J-receptors) and enhanced chemosensitivity of central and peripheral carbon dioxide receptors. (ersjournals.com)
  • In order to exclude patients with a significant obstructive and/or restrictive pulmonary disease, spirometric testing was performed. (ersjournals.com)
  • Electrocardiogram changes that may be seen in pulmonary embolism include sinus tachycardia, complete/incomplete (R) bundle branch block, S1Q3T3 pattern (deep S-wave in lead 1, pathological Q-wave and T-wave inversion in lead 3), ST elevation/T-wave inversion in inferior /septal leads. (racgp.org.au)
  • A number of clinical conditions (such as acute pulmonary embolism, heart failure, sepsis, pericarditis and stroke) can cause an elevation in troponin in the absence of acute coronary syndrome. (racgp.org.au)
  • Mrs. J. is a 63-year-old married woman who has a history of hypertension, chronic heart failure, and chronic obstructive pulmonary disease (COPD). (academicpapersresearch.com)
  • This essay will critically evaluate the scenario of Mrs. J, a 63-year-old married woman with a history of hypertension, chronic heart failure, and chronic obstructive pulmonary disease (COPD). (academicpapersresearch.com)
  • Corrective surgery is done to widen part of the narrowed pulmonary tract and close the ventricular septal defect with a patch. (medlineplus.gov)
  • The ambulance paramedics began treatment for pulmonary edema with oxygen, diuretics, and nitroglycerin and transported the D/O to the hospital's emergency department (ED). Shortly after arriving in the ED, the D/O had a cardiac arrest. (cdc.gov)
  • And Dr. Jonathan Whiteson, who's a medical director of Cardiac and Pulmonary Rehabilitation, and codirector of NYU Post-COVID Care Program at Rusk Rehabilitation NYU Langone Health. (cdc.gov)
  • The objective of this study is to evaluate whether corticosteroid treatment after LOA is beneficial for cardiac or pulmonary functions among boys with DMD. (cdc.gov)
Pacemaker19
  • Cardiac resynchronisation therapy (CRT or CRT-P) is the insertion of electrodes in the left and right ventricles of the heart, as well as on occasion the right atrium, to treat heart failure by coordinating the function of the left and right ventricles via a pacemaker, a small device inserted into the anterior chest wall. (wikipedia.org)
  • CRT with pacemaker only is often termed "CRT-P" to help distinguish it from CRT with defibrillator (CRT-D). The key indication for CRT is left bundle branch block (LBBB) of the heart, a cardiac abnormality leading to delayed left ventricular contraction. (wikipedia.org)
  • For CRT, a pacemaker is implanted below the collarbone and three leads are attached in the heart to resynchronise the contraction by stimulation with pulses of electricity. (escardio.org)
  • Pacemaker is a small electronic device, implanted below the collarbone and are connected to the heart with wires or leads to the right chambers of the heart. (taiwannews.com.tw)
  • Three wires (leads) are attached to the pacemaker and keep the ventricles pumping together by sending small electrical impulses to the heart muscle. (clevelandclinic.org)
  • I am a Staff Cardiac Electrophysiologist and the Director of Pacemaker and ICD Clinic, Massachusetts General Hospital, Boston, MA. (massgeneral.org)
  • Atrial ventricular nodal ablation is recommended for patients refractory to medical therapy, usually older patients needing a pacemaker. (aafp.org)
  • The world's biggest medical device company said studies suggest His bundle pacing may achieve better outcomes in some patients than the conventional approach to pacemaker lead placement. (medtechdive.com)
  • There can be different treatments for the disease of heart failure and one of them is the pacemaker. (phdsc.org)
  • When irregularities occur in the contraction of the cardiac muscles, an artificial Pacemaker can be used to treat those irregularities. (phdsc.org)
  • A pacemaker can slow down the process of heart failure. (phdsc.org)
  • The pacemaker is not only used to treat the rhythmic irregularities caused by heart failure but also to cure the bradycardia. (phdsc.org)
  • The pacemaker is the best solution to treat heart failure, which can give the patient a longer life and keep them out of hospital bed. (phdsc.org)
  • This will ensure the proper functioning of the heart along with the pacemaker. (phdsc.org)
  • These electrical impulses are triggered by the pacemaker which contracts the muscles of the heart and does the sufficient pumping of blood to the body. (phdsc.org)
  • The pacemaker contains three thin wires, called leads. (phdsc.org)
  • If there is any arrhythmic traction of the heart, then this can be cured by the pacemaker as it sends painless signals to the muscles through the leads. (phdsc.org)
  • So, the pacemaker justifies its name and makes the pace of the heart correct. (phdsc.org)
  • CRT is a treatment for heart failure that uses an implantable pacemaker to improve the heart's pumping efficiency by synchronizing the left and right ventricles. (meddeviceonline.com)
Congestive13
  • Following this report, multiple studies were published demonstrating the effectiveness of this technique in infants with congestive heart failure caused by large VSDs, complex lesions (eg, atrioventricular canal defects), and tricuspid atresia . (medscape.com)
  • An herbal medicinal substance, Crataegus Extract WS1442, safely extends the lives of congestive heart failure patients already receiving pharmacological treatment for the disease. (sciencedaily.com)
  • The herb is currently approved for use in some European countries to treat early congestive heart failure. (sciencedaily.com)
  • An herbal medicinal substance, Crataegus Extract WS®1442, safely extends the lives of congestive heart failure patients already receiving pharmacological treatment for the disease, according to a study presented at the American College of Cardiology's 56th Annual Scientific Session. (sciencedaily.com)
  • The herb is currently approved for use in some European countries to treat early congestive heart failure, a condition in which the heart cannot pump enough blood to the body's other organs. (sciencedaily.com)
  • A total of 2,681 patients with markedly impaired left ventricular function -- indicating advanced congestive heart failure -- were randomized to WS®1442 or placebo for a duration of two years. (sciencedaily.com)
  • WS 1442 is safe in patients with more severe congestive heart failure and left ventricular ejection fraction lower than 35 percent," said Dr. Holubarsch of Median Kliniken Hospitals in Bad Krozingen, Germany, and lead study author. (sciencedaily.com)
  • Dr. Holubarsch wil present "Crateagus Extract WS 1442 Postpones Cardiac Death in Patients With Congestive Heart Failure Class NYHA II-III: A Randomized, Placebo-Controlled, Double-Blind Trial in 2,681 Patients" on March 27 at the American College of Cardiology's 56th Annual Scientific Session. (sciencedaily.com)
  • 30, 2019 Infants less than six months old with Noonan Syndrome, hypertrophic cardiomyopathy and congestive heart failure normally have a poor prognosis, with a one-year survival rate of 34 percent. (sciencedaily.com)
  • We estimate that about one in 20 CABG patients who have congestive heart failure are in this category from the volume of patients we see here at Hopkins," says Conte. (hopkinsmedicine.org)
  • Review of published literature in peer-reviewed journals on the use of coenzyme Q10 as an adjunct to conventional therapy in patients with congestive heart failure and cardiomyopathy shows that there is strong evidence in favor of significant clinical improvement with coenzyme Q10 supplementation. (thewallachfiles.com)
  • Therefore, coenzyme Q10 supplementation as supportive therapy for patients with or at risk for congestive heart failure or cardiomyopathy is justified and appropriate, since it can afford significant clinical benefit to the patients. (thewallachfiles.com)
  • Coenzyme Q10 supplementation may help reduce the risk for congestive heart failure and cardiomyopathy. (thewallachfiles.com)
Catheterization4
  • Our center is now expanding the range of systematic care to accelerate the surgical preparation for heart failure and catheterization in patients with acute coronary syndromes. (cmuh.org.tw)
  • There are four cardiac catheterization rooms in which about 200 emergent cardiac catheterizations, 4000 cardiac catheterization, 700 coronary arterial drug-eluting stents placement and about 20 carotid artery stentings are performed every year. (cmuh.org.tw)
  • Every year since 2012, we have held national cardiac catheterization surgical demonstration and conference in February or March to display techniques for difficult cardiac catheterization which attracts interventional personnel come here sharing experiences. (cmuh.org.tw)
  • Contractility is difficult to measure clinically (because it requires cardiac catheterization with pressure-volume analysis) but is reasonably reflected by the ejection fraction (EF), which is the percentage of end-diastolic volume ejected with each contraction (stroke volume/end-diastolic volume). (msdmanuals.com)
Dysfunction14
  • Transthoracic echocardiography , the most widely available initial standard of care test for ventricular dysfunction, can help differentiate ischemic and nonischemic etiologies of cardiomyopathies. (medscape.com)
  • Myocardial strain imaging, a reproducible measure of LV systolic function, can identify subclinical LV dysfunction and patterns that suggest specific cardiomyopathies (eg, ischemic cardiomyopathy, amyloidosis, hypertrophic cardiomyopathy, chemotherapy-induced cardiotoxicity). (medscape.com)
  • In patients with ischemic cardiomyopathy, TTE may show segmental areas of systolic dysfunction that are typically localized to a coronary distribution. (medscape.com)
  • The association between increased arterial stiffness and left ventricular diastolic dysfunction (LVDD) may be influenced by left ventricular performance. (medsci.org)
  • brachial-ankle pulse wave velocity, P wave dispersion, left ventricular diastolic dysfunction. (medsci.org)
  • The cardiac mortality and morbidity were increased in heart failure patients with left ventricular diastolic dysfunction (LVDD) [ 1 , 2 ]. (medsci.org)
  • Some postulated that excess catecholamine released during stress can induce an exaggerated sympathetic response precipitating severe, reversible LV dysfunction in patients without coronary disease.2 Whether there is a genetic component is not well understood. (jefferson.edu)
  • Heart failure (HF) is a syndrome of ventricular dysfunction. (msdmanuals.com)
  • therefore, patients usually have moderate-severe left ventricular dysfunction when diagnosed with cardiac sarcoidosis, which may decrease the effectiveness of therapies. (go.jp)
  • Diastolic dysfunction has a major impact on symptom status, functional capacity, medical treatment, and prognosis in both systolic and diastolic heart failure (HF), irrespective of the cause. (bmj.com)
  • Diastolic dysfunction is the predominant cardiac abnormality in this syndrome, which is associated with increased risk of hospitalisation and death. (bmj.com)
  • Indeed, such a definition of diastolic HF has been adopted by the majority of previous reports, w5 and is supported by the results of recent studies which indicate that the presence of diastolic dysfunction may be assumed in patients presenting with HF and normal LV ejection fraction (LVEF). (bmj.com)
  • Echocardiographic assessment of diastolic function makes the diagnosis of diastolic HF more specific, allows serial assessment of the response of diastolic dysfunction to treatment, and facilitates inclusion of more homogeneous populations into intervention trials. (bmj.com)
  • Respiratory complications have long been recognized as the most significant contributor to morbidity and mortality in DMD patients, but complications due to cardiac dysfunction are becoming an increasingly significant as patients with DMD survive longer. (cdc.gov)
Severe11
  • CRT and CRT-D have become increasingly important therapeutic options for patients with moderate and severe heart failure. (wikipedia.org)
  • Bilateral renal arteriography revealed new severe ostial stenosis of the left renal artery and a patent right renal artery in which balloon angioplasty was performed 14 years ago. (bvsalud.org)
  • CONCLUSIONS This case features a patient who developed severe ARAS with underlying history of bilateral renal artery FMD. (bvsalud.org)
  • The most serious risks associated with YONDELIS are neutropenic sepsis (severe infections due to decreased white blood cells), rhabdomyolysis (severe muscle problems), cardiomyopathy (heart muscle problems, including heart failure), hepatotoxicity (liver problems, including liver failure), anaphylaxis, and extravasation (leakage of YONDELIS out of the vein during infusion) leading to tissue necrosis (tissue cell damage or death) and embryofetal toxicity. (prnewswire.com)
  • There was a late-peaking LV outflow tract gradient of 77 mm Hg consistent with severe, dynamic left ventricular outflow tract (LVOT) obstruction. (jefferson.edu)
  • Coronary angiography images showed severe stenosis of the left anterior descending coronary artery, which was dilated by percutaneous transluminal coronary angioplasty. (medscape.com)
  • Digoxin may cause severe sinus bradycardia or sino-atrial block particularly in patients with pre-existing sinus node disease and may cause advanced or complete heart block in patients with pre-existing incomplete AV block. (wikidoc.org)
  • Diphtheria causes a spectrum of clinical disease, ranging from cutaneous forms to severe respiratory infections with systemic complications, including cardiac and neurologic. (cdc.gov)
  • Severe diphtheria is usually associated with cardiac and neurologic complications because of the high affinity of diphtheria toxin with theses tissues ( 11 ). (cdc.gov)
  • Prolonged retention in clothing and rubber boots may lead to chemical dermatitis and severe burns. (cdc.gov)
  • Duchenne muscular dystrophy (DMD) is a severe neuromuscular disorder resulting in progressive muscle weakness, cardiac failure, and respiratory compromise. (cdc.gov)
Renal15
  • Consider phospholipidosis as a possible cause of renal injury in patients with underlying connective tissue disorders. (nih.gov)
  • Besides medical therapy, percutaneous renal angioplasty was supposed to be the most effective therapy for atherosclerotic renovascular disease, by leading to blood flow restoration. (bvsalud.org)
  • However, despite an apparently solid rationale, several randomized clinical trials failed to confirm the favorable effects of percutaneous renal angioplasty on blood pressure control, kidney function, cardiovascular and renal outcomes, previously reported in observational, retrospective and single-center cohorts, switching off the enthusiasm for this procedure. (bvsalud.org)
  • Several studies' limitations may partly account for this failure, including heterogeneity of diagnostic techniques, overestimation of the degree of renal artery stenosis, inappropriate timing of revascularization, multiple protocol revisions, frequent crossovers, and most importantly exclusion of patients at higher likelihood to respond to angioplasty. (bvsalud.org)
  • LANOXIN dose is based on patient-specific factors (age, lean body weight, renal function, etc. (guidelinecentral.com)
  • In selecting a LANOXIN dosing regimen, it is important to consider factors that affect digoxin blood levels (e.g., body weight, age, renal function, concomitant drugs) since toxic levels of digoxin are only slightly higher than therapeutic levels. (guidelinecentral.com)
  • The recommended starting maintenance dose in adults and pediatric patients over 10 years old with normal renal function is given in Table 2 . (guidelinecentral.com)
  • Table 3 provides the recommended (once daily) maintenance dose for adults and pediatric patients over 10 years old (to be given once daily) according to lean body weight and renal function. (guidelinecentral.com)
  • Such impacts could lead to a multitude of conditions, such as chronic renal failure, cerebral vascular disease, or stenosis of blood vessels throughout the body. (bumrungrad.com)
  • Globally, approximately 2 million patients have been diagnosed with end-stage renal disease (ESRD), with an annual reported incidence of nearly 100,000 cases [ 1 ]. (e-ultrasonography.org)
  • Patients with ESRD require some form of renal replacement therapy, with hemodialysis typically being the preferred treatment. (e-ultrasonography.org)
  • Newer oral anticoagulants have a slightly lower risk of intracranial hemorrhage compared with warfarin (Coumadin), but dose adjustment is required in patients with renal disease. (aafp.org)
  • This analysis also revealed an OPCAB benefit concerning post-operative renal failure, blood transfusion requirement and peri-operative inotropic support. (ecrjournal.com)
  • Low body weight, advanced age or impaired renal function, hypokalemia , hypercalcemia , or hypomagnesemia may predispose to digoxin toxicity. (wikidoc.org)
  • Beta thalassaemia syndromes are the other tissues such as cardiac or renal aly, clinical heart failure, and chelation most common inherited haemoglobi- tissue have different mechanisms and therapy with a method other than using nopathies caused by a genetic deficiency kinetics of iron uptake, storage and desferrioxamine. (who.int)
Hypertrophy5
  • CRT effects are related to alterations in genes and microRNAs (miRs) expression, which regulate cardiac processes involved in cardiac apoptosis, cardiac fibrosis, cardiac hypertrophy and angiogenesis, and membrane channel ionic currents. (hindawi.com)
  • We report a Chinese man with MM accompanied with both acute right heart failure and left ventricular hypertrophy. (biomedcentral.com)
  • This is the first report of reversible cardiac function impairment and left ventricular hypertrophy in a case of adult-onset MM, nocturnal hypoxia is a potential mechanism for left ventricular hypertrophy in patients with MM. (biomedcentral.com)
  • Here we report a case of MM which presented with reversible cardiac function impairment and left ventricular hypertrophy. (biomedcentral.com)
  • Additional autopsy findings included coronary artery disease, cardiomegaly (enlarged heart), and left ventricular hypertrophy (LVH). (cdc.gov)
Mortality18
  • Although mitral valve repair and replacement can successfully treat many patients with mitral valvular insufficiency, techniques currently in use are attended by significant morbidity and mortality. (justia.com)
  • The mortality rate of calcific aortic stenosis is high in patients not treated surgically. (cmuh.org.tw)
  • While two-year survival rates among heart failure patients have advanced dramatically over the last 20-30 years, at least for those who receive advanced treatment, it still has a high mortality rate despite existing treatments. (pharmatimes.com)
  • in particular, diabetic patients treated with insulin had a threefold higher mortality risk compared to nondiabetic patients, while diabetic patients not treated with insulin had only a modestly and nonsignificantly higher mortality risk (HR 1.59) compared to nondiabetic patients with HF [ 22 ]. (hindawi.com)
  • Cardiogenic shock is the leading cause of death in acute MI, with mortality rates of up to 70-90% in the absence of aggressive, highly experienced technical care. (medscape.com)
  • This benefit will be demonstrated using a composite endpoint of mortality, morbidity and cardiac function. (massgeneral.org)
  • Long-term hemodialysis typically necessitates vascular access in the upper extremity, either through an arteriovenous fistula (AVF) or an arteriovenous graft (AVG). Central venous catheters can also provide vascular access for patients undergoing hemodialysis, but these devices are associated with a substantial risk of infection, which increases morbidity and mortality. (e-ultrasonography.org)
  • It worsens heart failure and increases mortality in patients with myocardial infarction, and is an independent risk factor for death. (aafp.org)
  • Due to underpowered design for infrequent complications they usually failed to demonstrate a significant benefit of OPCAB surgery on early mortality and perioperative major cardiac and cerebrovascular events. (ecrjournal.com)
  • These studies demonstrated a trend towards lower peri-operative mortality for OPCAB compared with CCAB patients, but without reaching statistical significance. (ecrjournal.com)
  • In a meta-analysis of nine studies and 3,223 patients with an EF of 30-40%, the 30-day mortality was 3.8% for OPCAB surgery and significantly lower than the 6.9% found for CCAB patients. (ecrjournal.com)
  • For these patients, significantly reduced peri-operative mortality and comparable long-term results were found. (ecrjournal.com)
  • One study demonstrated a peri-operative mortality of 1.9% for OPCAB that was significantly lower than the 6.4% found for CCAB patients. (ecrjournal.com)
  • Among birth defects, congenital heart disease is the leading cause of infant mortality. (msdmanuals.com)
  • CRT devices have been shown to improve left ventricular function and reduce morbidity and mortality in patients with cardiac synchronization problems. (meddeviceonline.com)
  • The prediction of in-hospital mortality in chronic kidney disease patients with coronary artery disease using machine learning models. (cdc.gov)
  • Coronary artery bypass grafting (CABG) is performed for patients with coronary artery disease (CAD) to improve quality of life and reduce cardiac-related mortality. (medscape.com)
  • CAD is the leading cause of mortality in the United States, Europe, and Australia. (medscape.com)
Shortness of bre2
  • One week before admission, the patient developed shortness of breath in a supine position at night, which improved after 3-5 minutes of rest in the sitting position. (biomedcentral.com)
  • I began to experience a shortness of breath in random waves that didn't leave me gasping for air but certainly made me uncomfortable and very worried. (bmj.com)
Tachycardia2
Echocardiography4
  • In this overview based on the latest research, we discuss the integral role of comprehensive imaging studies, particularly transthoracic echocardiography (TTE) and cardiac magnetic resonance imaging (CMR), in differentiating potential causes of HF and diagnosing various cardiomyopathies. (medscape.com)
  • Myocardial strain imaging uses speckle-tracking echocardiography to measure tissue deformation through the cardiac cycle. (medscape.com)
  • Echocardiography is the primary modality for initial evaluation of symptomatic patients. (sts.org)
  • Doppler echocardiography is ideally suited for assessment of diastolic function, being widely available, non-invasive, and less expensive than other techniques. (bmj.com)
Sudden cardi4
  • The primary endpoint of the study was time to first cardiac event, including sudden cardiac death, death due to progressive heart failure, fatal heart attack, non-fatal heart attack or hospitalization due to heart failure. (sciencedaily.com)
  • It postpones death of cardiac cause after 18 months and sudden cardiac death in an important subgroup of patients. (sciencedaily.com)
  • Given the D/O's underlying heart disease, NIOSH investigators concluded that the physical stress of responding to the call and ascending/descending the aerial ladder to the roof of a three-story building probably triggered his sudden cardiac death. (cdc.gov)
  • On November 11, 2012, a 61-year-old male career D/O suffered sudden cardiac death after responding to a call about a burning odor in a residential structure. (cdc.gov)
Normal ventricular1
  • There are a few reported cases of Takotsubo in family members, one case of two sisters and another mother-daughter pair.3,4 Recurrence of the syndrome in the same patient, although rare, can occur and suggests a genetic predisposition.5 Majority of patients regain normal ventricular function within one to four weeks if they survive the acute episode. (jefferson.edu)
Fibrillation1
  • Treatment of these patients with digoxin leads to greater slowing of conduction in the atrioventricular node than in accessory pathways, and the risks of rapid ventricular response leading to ventricular fibrillation are thereby increased. (wikidoc.org)
Clinical26
  • Further work is needed to track clinical outcomes in patients with these factors to determine thresholds for enrolling participants in alternative forms of CR. (journaltocs.ac.uk)
  • Patients with severely reduced left ventricular function but stable clinical conditions and a minimal peak V̇ o 2 of at least 15 ml/kg/min during a symptom-limited exercise stress test tolerate water immersion and swimming in thermoneutral water well. (bmj.com)
  • Iclusig was initially approved in December 2012 under the FDA's accelerated approval program, which provides patients earlier access to promising new drugs that treat serious conditions based on a surrogate endpoint while the company conducts additional studies to confirm the drug's clinical benefit. (businesswire.com)
  • This full approval and label update is based on 48-month follow-up data (as of August 2015) from the pivotal Phase 2 PACE clinical trial of Iclusig in heavily pretreated patients with resistant or intolerant CML or Ph+ ALL. (businesswire.com)
  • Our clinical experiences with LS has shown that it reduces conventional inotropic agents dosages and could be a satisfactory agent in myocardial depression therapy which occurred in CPB surgery intraoperatively also in pediatric patients. (ispub.com)
  • The mechanics and structure of the healing infarct have been the focus of numerous pre-clinical and clinical investigations, leading to the impending clinical introduction of material injections as a means to favorably alter remodeling outcomes. (sc.edu)
  • These patients need repeat diagnostic testing and treatment with medial optimization with or without endovascular revascularization in the appropriate clinical setting. (bvsalud.org)
  • The approval was based on recently published clinical efficacy and safety data from the Phase 3, randomized, open-label, controlled study (ET743-SAR-3007), which evaluated YONDELIS versus the chemotherapy agent dacarbazine, in patients with unresectable or metastatic LPS or LMS previously treated with an anthracycline and at least one additional chemotherapy regimen. (prnewswire.com)
  • Most recently, my team became the first in Florida and one of the first in the world to begin enrolling patients in the CHAMPION-AF Clinical Trial. (pontevedrarecorder.com)
  • In literature the most relevant studies and clinical trials on CRT-D clinical outcomes regard enrolled patients with mean age under 70 years. (hindawi.com)
  • Patients with MMs have diverse clinical manifestations. (biomedcentral.com)
  • For adults and pediatric patients if a loading dosage is to be given, administer half the total loading dose initially, then ÂĽ the loading dose every 6-8 hours twice, with careful assessment of clinical response and toxicity before each dose. (guidelinecentral.com)
  • The aim of the present study was the investigation of ASV effects on clinical and functional parameters in patients with HFNEF compared to a control group of patients who rejected therapy for various reasons. (ersjournals.com)
  • All patients had to be in a stable clinical condition and in New York Heart Association (NYHA) class II-III. (ersjournals.com)
  • The clinical definition of cardiogenic shock is decreased cardiac output and evidence of tissue hypoxia in the presence of adequate intravascular volume. (medscape.com)
  • Resynchronization can be achieved by biventricular pacing (BVP), which leads to clinical improvement and reverse remodeling. (biomedcentral.com)
  • At Mass General, the brightest minds in medicine collaborate on behalf of our patients to bridge innovation science with state-of-the-art clinical medicine. (massgeneral.org)
  • Medtronic is involved in research to drive the field forward, including a 70-patient clinical trial that is assessing the rate of implant success in His bundle pacing. (medtechdive.com)
  • 1 Clinical management requires a whole-patient perspective. (bmj.com)
  • Broadly, such patients can be divided into those who may have serious sequelae (such as thromboembolic complications) and those with a non-specific clinical picture, often dominated by fatigue and breathlessness. (bmj.com)
  • Adverse clinical consequences associated with conventional coronary artery bypass surgery (CCAB) have largely been attributed to cardiopulmonary bypass circuit (CPB), hypothermic cardiac arrest, aortic cannulation and cross-clamping. (ecrjournal.com)
  • 3 However, the American College of Cardiology/American Heart Association guidelines for the evaluation and management of HF w4 support a diagnosis of exclusion-that is, clinical evidence of HF with preserved systolic function. (bmj.com)
  • These data suggest that a diagnosis of diastolic HF may accurately be made as a diagnosis of exclusion, 4 albeit in a highly selected population of relatively young, predominantly male patients who were scheduled to undergo cardiac catheterisation (contrasting with the large clinical population of elderly, hypertensive, predominantly female patients with HF and preserved systolic function). (bmj.com)
  • many such patients may in fact have non-HF causes of their clinical presentations. (bmj.com)
  • Combining Clinical and Genetic Data to Predict Response to Fingolimod Treatment in Relapsing Remitting Multiple Sclerosis Patients: A Precision Medicine Approach. (cdc.gov)
  • And apply health equity considerations to clinical care, activity management and reconditioning of long COVID patients. (cdc.gov)
Diastolic pressure2
  • Preload represents the degree of end-diastolic fiber stretch and end-diastolic volume, which is influenced by ventricular diastolic pressure and the composition of the myocardial wall. (msdmanuals.com)
  • Typically, left ventricular (LV) end-diastolic pressure, especially if higher than normal, is a reasonable measure of preload. (msdmanuals.com)
Complications6
  • Regardless of the type of vascular access used, it is necessary to conduct surveillance through physical examination and imaging to identify potential complications and access failure. (e-ultrasonography.org)
  • These wires can break or otherwise fail, leading to complications in roughly 5-10 percent of cases. (meddeviceonline.com)
  • The company's patented, proprietary technology was developed to eliminate the need for cardiac pacing leads, historically the major source of complications and reliability issues in cardiac rhythm disease management. (meddeviceonline.com)
  • We also review the cardiac complications of diphtheria and discuss how noninvasive bedside imaging technologies to monitor myocardial function and hemodynamic parameters can help improve the management of this neglected infectious disease. (cdc.gov)
  • These patients are also more likely to experience perioperative complications after CABG. (medscape.com)
  • As muscle weakness progresses, patients are increasingly at risk for orthopedic complications, such as fractures and scoliosis, and respiratory complications, such as hypoventilation and pneumonia. (cdc.gov)
Therapy14
  • These results solidify ponatinib as an important and valuable treatment option for refractory patients with CML where no other TKI therapy is appropriate, including those who have the T315I mutation," stated Jorge Cortes, M.D., professor and deputy chair, Department of Leukemia, The University of Texas MD Anderson Cancer Center, and a leading investigator in the PACE trial. (businesswire.com)
  • Since YONDELIS was first approved in Europe in 2007, approximately 50,000 patients in close to 80 countries have benefited from this therapy across all indications. (prnewswire.com)
  • Cardiac resynchronisation therapy (CRT), or biventricular pacing, is used to treat heart failure patients with left bundle branch block. (escardio.org)
  • The cardiovascular medicine specialists at Lahey Hospital & Medical Center are committed to offering tailored therapy for patients with advanced heart failure. (lahey.org)
  • 21 initially rejected treatment, withdrew from treatment or presented noncompliant during follow-up (controls), whereas ongoing ASV therapy was initiated in 39 patients (ASV group). (ersjournals.com)
  • 35%. These patients will be randomized to receive a LifeVest external defibrillator as opposed to medical therapy. (massgeneral.org)
  • However, heart bypass surgery performed by highly trained and experienced surgeons, followed by subsequent cardio therapy under the guidance of an expert nursing team, may sometimes be required. (bumrungrad.com)
  • Selection of therapy should be individualized based on risks and potential benefits, cost, and patient preference. (aafp.org)
  • All patients received medical treatment including supportive measures and guideline-supported medical therapy, which included automatic implantable cardioverter-defibrillator or wearable cardioverter-defibrillator in some patients. (acc.org)
  • Also, patients who discontinued the drugs had a lower incidence of the primary endpoint of death, non-fatal stroke and rehospitalization for heart failure versus those who continued the abuse methamphetamines while on medical therapy, 57 percent vs. 13 percent, respectively. (acc.org)
  • CE Mark approval gives EBR Systems the ability to train and educate physicians in the European Union on the use of the WiSE System, enabling more patients to benefit from this innovative therapy. (meddeviceonline.com)
  • In a study of 35 patients who had failed conventional CRT therapy, 97% were implanted successfully with WiSE Technology. (meddeviceonline.com)
  • In addition, approximately 30 percent of patients receiving conventional CRT do not respond to the therapy. (meddeviceonline.com)
  • [ 9 , 10 ] By the 1970s, CABG was found to increase survival rates in patients with multivessel disease and left main disease when compared with medical therapy. (medscape.com)
Acute11
  • We cooperate with the emergency room to make an accurate diagnosis and utilize the latest coronary angiography and interventional equipment to restore blood flow in patients with acute myocardial infarction in order to decrease myocardial damage and improve prognosis. (cmuh.org.tw)
  • Aug. 27, 2021 New guidelines for the diagnosis and treatment of acute and chronic heart failure have just been published. (sciencedaily.com)
  • The most common acute ECG findings of takotsubo cardiomyopathy are ST segment elevation in the praecordial leads and T-wave inversion in most leads. (racgp.org.au)
  • This differs from the typical ECG changes in an acute STEMI, which include elevation of the ST segments in contiguous leads accompanied by reciprocal ST depression in leads remote from the site of an acute infarct. (racgp.org.au)
  • Prevalence has been shown to be between 1.2-2.2% of all patients that present with suspected acute coronary syndrome. (racgp.org.au)
  • Unlike in acute myocardial infarction, most patients with takotsubo cardiomyopathy have a small but rapid increase in cardiac enzyme and biomarker levels. (racgp.org.au)
  • Patient with an acute anterolateral myocardial infarction who developed cardiogenic shock. (medscape.com)
  • A myocardial infarction caused by acute stenosis of a blood vessel supplying the heart is one of the most common conditions, and is usually a result of either NCDs not being monitored closely enough or the natural aging process. (bumrungrad.com)
  • The specialist rehabilitation needs of a third group, covid-19 patients whose acute illness required intensive care, have been covered elsewhere. (bmj.com)
  • Today, she has been admitted to the hospital ICU with acute decompensated heart failure and acute exacerbation of COPD. (academicpapersresearch.com)
  • Explainable machine learning model for predicting furosemide responsiveness in patients with oliguric acute kidney injury. (cdc.gov)
Reduced left ventricu1
  • In patients aged ≥60 yrs, its prevalence reaches that of heart failure with reduced left ventricular ejection fraction (HFREF), and, by the eighth decade, it is more frequent than HFREF. (ersjournals.com)
Impairment1
  • 2 Thus, diastolic evaluation is an important component of the evaluation of the patient with systolic left ventricular (LV) impairment. (bmj.com)
Surgical4
  • Although the use of PAB has declined, it remains an essential technique for comprehensive surgical treatment in patients with congenital heart disease. (medscape.com)
  • Surgical intervention may be indicated depending if patients are symptomatic or significant obstruction to flow and distortion of valve function is present. (sts.org)
  • In a study to be presented Jan. 28 at the 44th annual meeting of the Society of Thoracic Surgeons in Fort Lauderdale, Fla., the Hopkins team found that by combining so-called coronary artery bypass grafting, known as CABG, with surgical ventricular restoration, or SVR, in patients with advanced heart failure, the likelihood of subsequent heart problems was 24 percent, compared to 55 percent in those undergoing CABG alone. (hopkinsmedicine.org)
  • Surgical ventricular restoration can be performed with minimal training and by any cardiac surgeon," says Conte, who has performed nearly 150 of the dual procedures since 2000. (hopkinsmedicine.org)
Pediatric15
  • Treatment of uncomplicated malaria due to Plasmodium falciparum, Plasmodium malariae, Plasmodium ovale , and Plasmodium vivax in adult and pediatric patients. (nih.gov)
  • However, experiences about the use of LS in pediatric patients are limited. (ispub.com)
  • However the need for serial randomized controlled studies in pediatric patient about the use of LS is indisputable. (ispub.com)
  • Increasing myocardial contractility in pediatric patients with heart failure. (guidelinecentral.com)
  • Use digoxin solution to obtain the appropriate dose in infants, young pediatric patients, or patients with very low body weight. (guidelinecentral.com)
  • Pediatric cardiac tumors are extremely rare. (sts.org)
  • Nadas and Ellison reported the prevalence of pediatric cardiac tumors (primary and metastatic) to be 0.027% in 11,000 pediatric autopsies. (sts.org)
  • and thus, the true population based prevalence of pediatric cardiac tumors remains largely unknown. (sts.org)
  • Pediatric cardiac tumors are extremely rare, and the vast majority are benign. (sts.org)
  • Over a period of fifteen years, 27,640 pediatric patients were assessed for cardiac disease at The Hospital for Sick Children, Toronto. (sts.org)
  • The higher fetal prevalence as compared to the pediatric autopsy studies highlight probable in-utero demise or the natural post-natal regression that occurs with certain primary cardiac tumor subtypes. (sts.org)
  • Malignant tumors of the heart constitute approximately 10% of all pediatric tumors. (sts.org)
  • The frequency of pediatric cardiac tumors varies across the fetal, neonatal and pediatric age spectrum. (sts.org)
  • These are benign tumors that arise from the cardiac myocyte and constitute the most common pediatric cardiac tumors. (sts.org)
  • There is limited information regarding Off-Label Guideline-Supported Use of SandboxAlonso in pediatric patients. (wikidoc.org)
Hypertension9
  • Dilated cardiomyopathy occurs as a consequence of many different disease processes that impair myocardial function, such as coronary artery disease and hypertension. (justia.com)
  • However, as our population ages, it can become increasingly common to see patients who previously had FMD who develop ARAS at an advanced age, indicated by recurrent renovascular hypertension. (bvsalud.org)
  • CASE REPORT We present a case of a 66-year-old female patient who, in 2007, had presented with uncontrolled hypertension. (bvsalud.org)
  • Clinicians need to be aware that in patients with FMD, worsening renovascular hypertension at an advanced age could indicate the development of new hemodynamically significant ARAS. (bvsalud.org)
  • Atherosclerotic renovascular disease is the most frequent cause of renovascular hypertension and its prevalence increases with age and in specific subset of patients, such as those with end-stage chronic kidney disease, heart failure, and coronary artery disease. (bvsalud.org)
  • Sectral (acebutolol hydrochloride) is a beta-blocker used to treat hypertension ( high blood pressure ) and heart rhythm disorders . (rxlist.com)
  • The patient denied any history of hypertension, diabetes, or smoking. (biomedcentral.com)
  • Maintaining the health of the heart is also very important, but due to some reasons such as Hypertension or High Blood Pressure, the heart can become weak, and it can eventually this might lead to Heart Failure. (phdsc.org)
  • Side effects such as weight gain, hypertension, and glucose intolerance, and effects on growth and bone density are compounded in non-ambulatory patients with active declines in heart and lung function. (cdc.gov)
Contractility2
  • Most inotropes used in the clinics function by increasing the levels of cytosolic calcium (Ca +2 ), whereas levosimendan (LS) stimulates myocardial contractility without raising the intracellular Ca +2 concentration [ 1 2 ]. (ispub.com)
  • Expect additive negative inotropic effects of mavacamten and other drugs that reduce cardiac contractility. (medscape.com)
Heart's1
  • Late-breaking results from the ElectroCRT trial presented today at EHRA 2019 1 a European Society of Cardiology (ESC) congress, pave the way for a new standard of care to improve the heart's pump function in selected patients with heart failure. (escardio.org)
Interventricular septum2
  • Some patients have LBBB secondary to coronary artery disease and an infarct involving the interventricular septum,some have heart failure and some "just" have a LBBB, the so called lone or isolated LBBB. (blogspot.com)
  • 1) Abnormal movement of the interventricular septum early in cardiac contraction ( systole) ie in the pre-ejection phase the septum moves to the left. (blogspot.com)
Myocardial oxygen1
  • The aims of premedication are to minimize myocardial oxygen demands by reducing heart rate and systemic arterial pressure and to improve myocardial blood flow with vasodilators. (medscape.com)
Abnormal10
  • Levosimendan (LS), a new inodilator used in the treatment of decompensate heart failure, has been reported to be effective in patients with high perioperative risks, with abnormal left ventricular function, and who face difficulties in weaning off cardiopulmonary bypass. (ispub.com)
  • This refers to abnormal timing of contraction of the left atrium (LA) with respect to the LV impairs cardiac function. (taiwannews.com.tw)
  • Some patients may have heart failure due to a Cardiomyopathy, which is when the heart muscle is abnormal and does not pump efficiently, due to weakening, abnormal thickening, or other systemic medical problems that can affect the heart. (lahey.org)
  • Sudden cardiac arrest (SCA) is a sudden death that happens when the heart stops working because of an abnormal heart rhythm. (clevelandclinic.org)
  • Congenital cardiac tumor is defined as a congenital malformation consisting of growth of abnormal tissue within the heart. (sts.org)
  • 4 w6 w7 Zile and colleagues demonstrated that at least one abnormal index of diastolic function was present in patients with HF and normal systolic function. (bmj.com)
  • With increases in the IVRT and IVCT there is less time for the ejection time which leads to an elevated or abnormal MPI ( myocardial performance index).The failing heart both contracts and relaxes more slowly and the MPI has been proposed as a useful prognostic indicator. (blogspot.com)
  • to characterize associations between corticosteroid use and onset of abnormal left ventricular (LV) function or abnormal percent predicted forced vital capacity (ppFVC) among 398 non-ambulatory boys with DMD. (cdc.gov)
  • We found no differences in time to onset of abnormal LV function by corticosteroid use groups. (cdc.gov)
  • Our findings show no association of corticosteroid use beyond LOA with the onset of abnormal LV function, but a significant association with a delay in onset of abnormal ppFVC. (cdc.gov)
Insufficiency3
  • Enlargement of the mitral annulus and left ventricular cavity produce mitral valvular insufficiency. (justia.com)
  • The long-term functional performance may be affected by residual atrioventricular valve insufficiency, ventricular aneurysms, and global myocardial reserve. (sts.org)
  • She also experiences anxiety and expresses fear of death, feelings of air insufficiency, and a sensation of her heart "running away. (academicpapersresearch.com)
Bundle branc3
  • The intraventricular dyssynchrony segment spearheaded the market in 2019 in terms of revenue attributed to comparatively higher incidence of intraventricular dyssynchrony among patients with heart failure and left bundle branch block. (taiwannews.com.tw)
  • This manifests as left bundle branch block in the surface ECG. (biomedcentral.com)
  • The EKG pattern of left bundle branch block (LBBB) has been known for decades and that pattern was considered an indication of heart disease. (blogspot.com)
Symptomatic patients1
  • The effect of reverse remodeling was evaluated on long-term survival in mildly symptomatic patients with heart failure submitted to CRT [ 10 ]. (hindawi.com)
Rhythm10
  • CRT defibrillators (CRT-D) also incorporate the additional function of an implantable cardioverter-defibrillator (ICD), to quickly terminate an abnormally fast, life-threatening heart rhythm. (wikipedia.org)
  • A cardiac device is used to keep your heart beating with a normal rhythm. (clevelandclinic.org)
  • This type of ICD sends a fast impulse to the heart muscle to get it back into a normal rhythm. (clevelandclinic.org)
  • Changes in heart rhythm keep the heart from sending blood to the rest of the body. (clevelandclinic.org)
  • The risk of dying increases about 10% every minute that goes by without treatment (CPR and defibrillation, which is essentially an emergency shock to get your heart back into rhythm). (clevelandclinic.org)
  • Many ICD and CRT devices have built-in features that let your doctor or nurse keep track of your heart rhythm, heart function, and your activity level. (clevelandclinic.org)
  • For most patients, rate control is preferred to rhythm control. (aafp.org)
  • Preliminary results of the recently completed SELECT-LV study were presented in mid-May by Mt. Sinai Hospital cardiologist and Professor of Medicine Vivek Reddy, M.D., at the Heart Rhythm Society Scientific Sessions in Boston. (meddeviceonline.com)
  • EBR Systems is dedicated to superior treatment of cardiac rhythm disease by providing more physiologically effective pacing throughWireless Stimulation Endocardially (WiSE). (meddeviceonline.com)
  • Objective findings reveal vital signs such as elevated heart rate, irregular heart rhythm, increased respiratory rate, low blood pressure, crackles in the lungs, decreased breath sounds, frothy blood-tinged sputum, low oxygen saturation, and hepatomegaly. (academicpapersresearch.com)
Abstract1
  • ABSTRACT There is a need for higly accurate non-invasive methods for assessing organ iron content in thalassaemia patients. (who.int)
Cardiopulmonary2
Respiratory1
  • Bernstein D. Cyanotic congenital heart disease: evaluation of the critically ill neonate with cyanosis and respiratory distress. (medlineplus.gov)
Cardiovascular8
  • In patients with severely reduced left ventricular function, this hydrostatically induced volume shift might overstrain the cardiovascular adaptive mechanisms and lead to cardiac decompensation. (bmj.com)
  • One patient dies every 36 seconds in the U.S. from cardiovascular disease. (taiwannews.com.tw)
  • Assessment of left ventricular diastolic function is useful in risk stratification for patients with cardiovascular disease and can provide a diagnostic clue for heart failure with preserved ejection fraction. (medsci.org)
  • The work presented today emphasizes the fact that the growing drug epidemic will have long term cardiovascular consequences in addition to the known short term tragic events," said Editor-in-Chief of JACC: Heart Failure Christopher O'Connor, MD, FACC. (acc.org)
  • The mission of the College and its more than 52,000 members is to transform cardiovascular care and to improve heart health. (acc.org)
  • JACC: Cardiovascular Interventions , JACC: Cardiovascular Imaging and JACC: Heart Failure also rank among the top ten cardiovascular journals for impact. (acc.org)
  • There is sound scientific rationale for an important role for coenzyme Q10 in the maintenance of cardiovascular health in general and in the management of heart disease and in particular heart failure. (thewallachfiles.com)
  • Describe four cardiovascular conditions that may lead to heart failure and what can be done in the form of medical/nursing interventions to prevent the development of heart failure in each condition. (academicpapersresearch.com)
Perioperative1
  • Successful perioperative management of a pregnant patient with ES is a challenge for anesthesiologists. (wjgnet.com)
Endocardial6
  • One repair technique which has been shown to be effective in treating incompetence, particularly of the mitral and tricuspid valves, is annuloplasty, in which the effective size of the valve annulus is contracted by attaching a prosthetic annuloplasty ring to the endocardial surface of the heart around the valve annulus. (justia.com)
  • An active fixation pacing lead was delivered to the mapped site of latest electrical activation on the endocardial LV. (ox.ac.uk)
  • CONCLUSION: LV endocardial pacing via interventricular septal puncture in patients for whom standard CRT is not possible is similarly effective and durable, with significant but potentially acceptable risks. (ox.ac.uk)
  • During the next 12 months, EBR Systems will continue working with leading European clinicians to assess different strategies for optimizing endocardial pacing location that maximize CRT benefits. (meddeviceonline.com)
  • Endocardial stimulation is generally considered more like the natural activation pattern of the heart than today's epicardial pacing techniques. (meddeviceonline.com)
  • Future products will address wireless endocardial stimulation for bradycardia and other non-cardiac indications. (meddeviceonline.com)
Ejection time1
  • Omecamtiv mercabil increased left ventricular ejection time and stroke volume compared to control, alongside a small reduction in heart rate, suggesting that the hearts were working more effectively and efficiently. (pharmatimes.com)
Stroke volume1
  • Although some patients with CHF showed a decrease of stroke volume during immersion, all subjects were able to increase cardiac index (by 87% in healthy subjects, by 77% in patients with CAD and by 53% in patients with CHF). (bmj.com)
Coronary sinus1
  • Right ventricular access is direct, while left ventricular access is conferred via the coronary sinus (CS). (wikipedia.org)
Velocity3
  • This study is designed to compare left ventricular diastolic function among patients divided by brachial-ankle pulse wave velocity (baPWV) and corrected P wave dispersion (PWDC) and assess whether the combination of baPWV and PWDC can predict LVDD more accurately. (medsci.org)
  • compared carotid-femoral pulse wave velocity and baPWV in 2287 patients and found a strong correlation between them [ 6 ]. (medsci.org)
  • In addition, significant positive effects could be confirmed on absolute and predicted peak oxygen consumption, oxygen consumption at the individual aerobic-anaerobic threshold, oxygen pulse, as well as left atrial size, and transmitral flow patterns (mean early diastolic lengthening velocity and the ratio of peak early Doppler mitral inflow velocity to this lengthening velocity). (ersjournals.com)
Pacing11
  • This treatment, also known as biventricular pacing, can be helpful for some patients with HF-rEF. (clevelandclinic.org)
  • 50%) and AV block will benefit from biventricular pacing compared to right ventricular pacing, as evidenced by a slowing in the progression of heart failure in patients receiving biventricular pacing. (massgeneral.org)
  • The Food and Drug Administration has cleared Medtronic's pacing lead for use in the stimulation of the bundle of His, being marketed as a new treatment option as an alternative to right ventricular pacing of the heart. (medtechdive.com)
  • Medtronic is the first company to bring a His bundle pacing lead to market in the U.S. (medtechdive.com)
  • For many patients with cardiac conditions, right ventricular pacing is safe and effective. (medtechdive.com)
  • Researchers have linked long-term right ventricular pacing to a higher risk of a range of adverse events, including heart failure and death. (medtechdive.com)
  • Pacing the His bundle sends impulses quickly across the right and left ventricles, ensuring they contract in unison. (medtechdive.com)
  • Medtronic has followed the trend, leading it to file to expand the label for its SelectSecure cardiac pacing lead. (medtechdive.com)
  • The label expansion marks the first time the FDA has cleared a lead for use in His bundle pacing. (medtechdive.com)
  • Those sound waves are converted to electrical energy, providing cardiac pacing. (meddeviceonline.com)
  • WiSE is the world's first and only wireless cardiac pacing system for heart failure. (meddeviceonline.com)
Septum2
  • In LBBB the activation pattern is markedly altered so that the septum is activated from right to left with early septal activation and contraction of septal area during the isovolumic contraction phase of systole and there is delay of the impulses arriving at the lateral and posterior left ventricular wall delaying muscle contraction. (blogspot.com)
  • HN - 2008 BX - Lateral Sinus MH - Atrial Septum UI - D054087 MN - A07.541.459.249 MS - The thin membrane-like muscular structure separating the right and the left upper chambers (HEART ATRIA) of a heart. (bvsalud.org)
Chronic5
  • To assess the haemodynamic response to water immersion, gymnastics and swimming in patients with chronic heart failure (CHF). (bmj.com)
  • We have performed EKOS in eight patients with lower limb chronic DVT, of which the number is the most in Taiwan and the first in Asia. (cmuh.org.tw)
  • and for the treatment of adult patients with T315I-positive CML (chronic phase, accelerated phase, or blast phase) or T315I positive Ph+ ALL. (businesswire.com)
  • The data on Iclusig continue to show that with a minimum follow-up of 48 months, many chronic phase CML patients in the PACE trial have retained long-term cytogenetic and molecular responses," stated Timothy P. Clackson, Ph.D., president of research and development and chief scientific officer at ARIAD. (businesswire.com)
  • Heart failure is among the most common chronic diseases in modern civilizations. (biomedcentral.com)
Survival6
  • The pivotal Phase 3 study enrolled over 500 patients and demonstrated an improvement in progression free survival (PFS) for patients treated with YONDELIS. (prnewswire.com)
  • The 4% greater increase in the electrical group is of a magnitude shown to improve functional response and cardiac event-free survival in previous studies, 4-6 indicating that the improvement is clinically important. (escardio.org)
  • Researchers plan to continue monitoring the study patients to better assess long-term survival rates. (hopkinsmedicine.org)
  • Evaluation of race/ethnicity-specific survival machine learning models for Hispanic and Black patients with breast cancer. (cdc.gov)
  • Although regular blood transfusion the liver and heart MRI T2* readings and written consent was received from has increased the survival rate among among patients, different degrees of all patients whose records were used. (who.int)
  • Because elderly patients have a shorter life expectancy, CABG may not necessarily prolong survival. (medscape.com)
Atrioventricular1
  • Atrioventricular (AV) dyssynchrony occurs when there is an unfavorable difference in timing between atrial and ventricular contractions. (taiwannews.com.tw)
Systole2
Cardiomyopathy3
  • Thanks to technologic advances in cardiac imaging, multimodality studies provide insight into the pathophysiology of both ischemic and nonischemic cardiomyopathy. (medscape.com)
  • Data is lacking to guide anticoagulation for LV thrombus prevention in patients with stress cardiomyopathy. (jefferson.edu)
  • Rather than simply placing patients with suspected methamphetamine associated cardiomyopathy on a cocktail of neurohormonal blockade, the majority of focus should be on helping such patients quit," he said. (acc.org)
LBBB6
  • In Dr. George Burch's text book, written over fifty years ago, A Primer of Heart Disease , I read that LBBB was a pathognomonic sign of heart disease. (blogspot.com)
  • However,at the time, It was not known what was the role of LBBB in altering cardiac function.Did it cause heart disease- this point is debated still. (blogspot.com)
  • Did patients with heart disease and enlarged hearts develop LBBB or similar EKG patterns as their disease progressed? (blogspot.com)
  • In LBBB they do not- the right contracts milliseconds before the left.So there is inter-ventricular loss of synchrony. (blogspot.com)
  • Consider what the development of LBBB does to an otherwise healthy heart and consider how that effect would be more manifest clinically in a diseased heart with failure. (blogspot.com)
  • Details regarding cardiac function in patients with LBBB and normal coronary arteries ( most were shown not to have coronary artery disease by angiography) were provided by Ozdemir who studied 45 cases of isolated LBBB ranging in age from 48 to 72. (blogspot.com)
Undergoing cardiac surgery1
  • LS is distinguished from other inotropic agents by this dual mechanism and considered as a good choice in high-risk patients undergoing cardiac surgery. (ispub.com)
Physiology1
  • Assessment of Cardiac Energy Metabolism, Function, and Physiology in Patients With Heart Failure Taking Empagliflozin: The Randomized, Controlled EMPA-VISION Trial. (ox.ac.uk)
Reduction1
  • Dr. Christian J. F. Holubarsch and his team saw a 20 percent reduction in cardiac-related deaths among patients on WS®1442, extending patients' lives by four months during the first 18 months of the study. (sciencedaily.com)
Assessment2
  • Recent advances in three-dimensional (3D) TTE allow automated detection of endomyocardial borders for accurate assessment of ventricular volumes and ejection fraction. (medscape.com)
  • Paradoxically, the role of diastolic function assessment is more difficult to define in patients with diastolic HF. (bmj.com)
Implantable2
  • An implantable cardiac defibrillator (ICD) is an electronic device that is placed inside the body. (clevelandclinic.org)
  • Two implantable devices used to occlude the appendage, the Watchman and the Amplatzer Cardiac Plug, appear to be as effective as warfarin in preventing stroke, but they are invasive. (aafp.org)
Myocardium1
  • Since the well tolerance of the myocardium, we were able to stop the other inotropic drug infusions after 48 hours and the patient was discharged from the hospital 10 days after the surgery. (ispub.com)
Significantly2
  • Although the use of PAB has significantly decreased, it continues to maintain a therapeutic role in certain subsets of patients with congenital heart disease. (medscape.com)
  • The majority of the patients were male (84 percent) and nearly half the group (44 percent) were classified as NYHA III, meaning they were significantly impaired by their heart condition. (sciencedaily.com)