• placebo
  • Primary care patients with a DSM-III-R/DSM-IV diagnosis of major depressive disorder were randomly assigned to imipramine (N=32) or placebo (N=31) treatment for 6 weeks, with possible prolongation to 18 weeks. (psychiatrist.com)
  • Despite greater clinical improvement at week 6, imipramine patients did not report greater increases than placebo patients in mean mQoL ratings. (psychiatrist.com)
  • 6 This compared paracetamol, diclofenac, and placebo over a 12 week period in 82 patients with knee OA but was the first negative study for paracetamol, showing no difference between paracetamol and placebo using Western Ontario McMaster Osteoarthritis Index (WOMAC) assessments. (bmj.com)
  • This is a 6 week double blind parallel group trial of paracetamol versus placebo in 779 patients with knee OA. (bmj.com)
  • symptoms
  • The FDA has recently identified these domains as important clinical targets for drug development because the antipsychotic agents used to treat patients with schizophrenia largely provide benefit for positive symptoms of the disease, such as hallucination or delusions. (drugs.com)
  • The quality of life and level of function for most of these patients continues to be dramatically affected by cognitive impairment and by negative symptoms as patients enter what has been called the residual phase of schizophrenia. (drugs.com)
  • Typically, elderly patients with depression do not report depressed mood, but instead present with less specific symptoms such as insomnia, anorexia, and fatigue. (wikipedia.org)
  • To meet criteria for a major depressive episode, a patient must have 5 of these 9 symptoms nearly every day for at least 2 weeks. (wikipedia.org)
  • Although antidepressants may not cure depression, they can lead to remission, which is the disappearance or nearly complete reduction of depression symptoms. (wikipedia.org)
  • clinical
  • WINSTON-SALEM, N.C.--(BUSINESS WIRE)--Apr 7, 2011 - Targacept, Inc. (NASDAQ: TRGT) today announced the presentation of data from a Phase 2 clinical proof of concept trial to assess TC-5619 as an augmentation therapy to improve cognition in patients with schizophrenia at the International Congress on Schizophrenia Research (ICOSR) in Colorado Springs, Colorado. (drugs.com)
  • A medical food thought to promote synapse formation was found to improve memory test scores in patients with mild Alzheimer's disease (AD) in a clinical trial presented at the 4th International Conference on Clinical Trials on Alzheimer's Disease (CTAD) in San Diego, California, on Friday, 4 November 2011. (alzforum.org)
  • The medication review programme led by a clinical pharmacist resulted in a substantial reduction in the use of inappropriate medications among hospitalised elderly patients and all-cause unscheduled readmissions at 1 month after hospital discharge. (hkmj.org)
  • 3 It has been shown that implementation of a clinical pharmacist service has a positive effect on medication use and health care service utilisation among hospitalised patients. (hkmj.org)
  • Although current European League Against Rheumatism (EULAR) 1 and American College of Rheumatology (ACR) 2 guidelines both support paracetamol (acetaminophen) as the first line oral analgesic for patients with knee osteoarthritis (OA), until now there has been a paucity of clinical trial data to confirm the efficacy of paracetamol in large joint OA. (bmj.com)
  • typically
  • Patients are typically not able to comparison shop for medical services based on price, as medical service providers do not typically disclose prices prior to service. (wikipedia.org)
  • 2-3 However, because FEVR is a lifelong disease, these patients are at risk even as adults.2 Ocular findings and useful vision typically remain stable if the patient does not have deterioration before age 20.2,4 Due to the variability and unpredictability of the disease course, patients with FEVR should be followed throughout their lifetime. (wikipedia.org)
  • mean
  • Despite these favorable findings, it is too early to know what they mean for AD patients. (alzforum.org)
  • In the analysis of prespecified secondary outcomes, there were significant differences in favour of surgery for low back pain (mean difference −12.2, −21.3 to −3.1), patients' satisfaction (63% (n=46) v 39% (n=26)), SF-36 physical component score (mean difference 5.8, 2.5 to 9.1), self efficacy for pain (mean difference 1.0, 0.2 to 1.9), and the Prolo scale (mean difference 0.9, 0.1 to 1.6). (bmj.com)
  • drop
  • As insurance premiums rise, more healthy people decide that it is not worth the higher prices, and drop out of the market, leading to what is called the "adverse selection death spiral. (wikipedia.org)
  • make
  • There is not enough evidence at this point to make a recommendation to patients," said Paul Aisen at the University of California, San Diego. (alzforum.org)
  • To make matters worse, he's gradually developing a phobia of his patients, being unable to empathise with their whining - which drives him to drink while on duty. (wikipedia.org)
  • outcomes
  • My starting point for this article is that you are impressed with the improvement in patient quality of life and cardiovascular outcomes of more frequent home hemodialysis (HD) and you recognize that many, but not all, of your patients will greatly benefit from this modality. (renalandurologynews.com)
  • time
  • Clinicians experience losses in the form of time spent on patient intakes, missed appointments prior to termination, and other diagnostic work performed. (wikipedia.org)
  • But if all physicians suddenly dropped to half or 1/3 time, wouldn't that do irreparable damage to patient access? (getbetterhealth.com)
  • Many health systems are putting in place price transparency initiatives and payments plans for their patients so that the patients better understand what the estimated cost of their care is, and how they can afford to pay for their care over time. (wikipedia.org)
  • An official report published in February 2009 stated that in 2008, for the first time, HIV/AIDS was China's leading cause of death among infectious diseases. (wikipedia.org)
  • adverse
  • Due to the risk-spreading design of insurance, the adverse selection associated with the young invincibles leads to higher premiums for people who choose to purchase health insurance. (wikipedia.org)
  • Social
  • But the social worker is the key to identifying potential changes in the home that may lead to patient burnout or dropout from the program. (renalandurologynews.com)
  • DBT can be based on a biosocial theory of personality functioning in which BPD is seen as a biological disorder of emotional regulation in a social environment experienced as invalidating by the borderline patient. (wikipedia.org)
  • lower
  • Participants 173 patients with a history of low back pain for at least one year, Oswestry disability index of at least 30 points, and degenerative changes in one or two lower lumbar spine levels (86 patients randomised to surgery). (bmj.com)
  • specifically
  • Specifically, DBT has been found to significantly reduce self-injury, suicidal behavior, impulsivity, self-rated anger and the use of crisis services among borderline patients. (wikipedia.org)
  • include
  • The aim is to include a total of 128 patients. (clinicaltrials.gov)
  • Pharmalogical neuroenhancement agents include the well-validated nootropics, such as racetam, vinpocetine, and phosphatidylserine, as well as other drugs used for treating patients suffering from neurological disorders. (wikipedia.org)
  • mild
  • To be included in the trial, patients had to have a Mini-Mental State Examination (MMSE) score greater than 20, which is considered mild AD. (alzforum.org)
  • In mild variations, patients may experience peripheral vascular changes, such as peripheral avascular zone, vitreoretinal adhesions, arteriovenous anastomoses and a V-shaped area of retinochoroidal degeneration. (wikipedia.org)
  • another
  • This can result in a spurious negative correlation between diseases: a hospital patient without diabetes is more likely to have another given disease such as cholecystitis, since they must have had some reason to enter the hospital in the first place. (wikipedia.org)
  • risk
  • Geriatric in-patients are at risk of drug-related problems. (hkmj.org)
  • The argument is that these individuals are young and in good health, so they have a low risk of experiencing substantial health issues that would lead to large amounts of spending on health care. (wikipedia.org)
  • disorders
  • Modafinil is currently licensed for treating patients with disorders such as narcolepsy, sleep apnea, and shift work sleep disorder. (wikipedia.org)
  • treatments
  • Several random controlled trials (RCTs) comparing DBT to other forms of cognitive-behavioral treatments have favored the use of DBT to treat borderline patients. (wikipedia.org)
  • physicians
  • Other services exist to assist physicians and their patients, such as Healthcare Out Of Pocket, Accuro Healthcare Solutions, with its CarePricer software. (wikipedia.org)
  • several
  • There are several sources of patients. (renalandurologynews.com)
  • The material is prepared by sulfonation of polystyrene: (CH2CHC6H5)n + n SO3 → (CH2CHC6H4SO3H)n Several methods exist for this conversion, which can lead to varying degree of sulfonation. (wikipedia.org)
  • experience
  • Based on some studies, personal experience, and discussions with colleagues, I believe a realistic number is 8%-10% of dialysis patients will embrace home HD. (renalandurologynews.com)
  • In the second stage, patients are encouraged to experience the painful emotions that they have been avoiding. (wikipedia.org)
  • different
  • This was conducted by setting up a large network of medical professionals and neighborhood organizations in order to obtain large samples of pertussis from as many different patients as possible. (wikipedia.org)
  • illness
  • He recognized it as a match for his own actions during his illness and renamed himself "e-Patient Dave," and his blog The New Life of e-Patient Dave. (wikipedia.org)
  • withdrawal
  • Patients dependent upon methadone or long-acting opioid products may be more susceptible to precipitated and prolonged withdrawal during induction than those on short-acting opioid products. (drugs.com)
  • Buprenorphine/naloxone combination products have not been evaluated in adequate and well-controlled studies for induction in patients on long-acting opioid products, and contain naloxone, which is absorbed in small amounts by the sublingual route and could cause worse precipitated and prolonged withdrawal. (drugs.com)
  • The first dose of SUBOXONE sublingual film or buprenorphine should be administered when objective signs of moderate opioid withdrawal appear, and not less than 6 hours after the patient last used an opioid. (drugs.com)
  • years
  • This problem of ballooning health insurance premiums has persisted for years, and was important in the debate over the Patient Protection and Affordable Care Act, commonly called the Affordable Care Act (ACA). (wikipedia.org)
  • group
  • But by 24 weeks the Souvenaid group had a more favorable trajectory on the memory score than controls, leading to a Cohen's d effect size of 0.22 points that Scheltens said was significant. (alzforum.org)
  • In February 2009 Ferguson's e-Patient Scholars Working Group elected him founding co-chair (with his physician, Dr. Danny Sands) of the Society for Participatory Medicine. (wikipedia.org)
  • The school offers the Personal Development Program in addition to the Peer Group Connections Program, a freshman orientation, and guidance program led by upperclassmen. (wikipedia.org)
  • life
  • Exploring the cost-utility relationship of rheumatoid arthritis patients treated with adalimumab by combining the Health Related Quality of Life of rheumatoid arthritis patients and direct as well as indirect costs due to RA. (clinicaltrials.gov)
  • Measurement of Health Related Quality of Life in Rheumatoid Arthritis patients 3. (clinicaltrials.gov)
  • At 18 weeks, remitted patients still showed deficits on ESM daily life measures relative to healthy controls, even though QoL had returned to normal on retrospective measures. (psychiatrist.com)
  • upon recovery from near-death he started a blog "The New Life of Patient Dave. (wikipedia.org)
  • Doctors
  • Hospitals, doctors, and other medical providers have traditionally disclosed their fee schedules only to insurance companies and other institutional payors, and not to individual patients. (wikipedia.org)
  • data
  • Richard Davies deBronkart Jr (born February 18, 1950), widely known as e-Patient Dave, is a cancer patient and blogger who, in 2009, became a noted activist for healthcare transformation through participatory medicine and personal health data rights. (wikipedia.org)
  • frequent
  • At conferences and meetings he is a frequent speaker about the "e-Patient" movement, also referred to as "patient engagement" and "participatory medicine. (wikipedia.org)
  • drug
  • The drug is contraindicated in patients with obstructive bowel disease and in newborn children with reduced gut motility. (wikipedia.org)
  • hospital
  • Four Norwegian hospitals will collaborate in this trial (Haukeland university hospital, Haugesund hospital, Haugesund sanitetsforenings hospital for rheumatic diseases and Lovisenberg diakonale hospital) and patients are recruited from all four hospitals. (clinicaltrials.gov)