• The artificial organ is an engineered device integrated into human living tissues to replace the human organ. (grandviewresearch.com)
  • In this topic, we will review the cells, tissues, and organs that make up the immune system. (pearson.com)
  • The second part consists of lymphoid organs and tissues including the bone marrow, lymph nodes, spleen, and thymus. (pearson.com)
  • Lymphoid organs and tissues are the sites where lymphocytes are produced, reside, and come in contact with pathogens. (pearson.com)
  • The lymphatic system is composed of a network of lymph vessels referred to as lymphatics, as well as certain organs and tissues, including the lymph nodes, bone marrow, spleen, thymus and GALT. (petplace.com)
  • EDEN PRAIRIE, Minn. & REHOVOT, Israel--( BUSINESS WIRE )-- Stratasys Ltd. (Nasdaq: SSYS) and CollPlant Biotechnologies (Nasdaq: CLGN) today announced a joint development and commercialization agreement to collaborate on the development of a solution to bio-fabricate human tissues and organs using Stratasys' P3 technology-based bioprinter and CollPlant's rh-Collagen-based bioinks. (biospace.com)
  • The P3 technology allows printing with high resolution and process control, and we believe that the combined, pioneering technologies of both companies will streamline the development and production process so that we have the most efficient means to produce our regenerative breast implants and other potential tissues and organs. (biospace.com)
  • This gene provides instructions for making a protein that plays a critical role in the formation of many different tissues and organs during embryonic development. (medlineplus.gov)
  • It provides the oxygen, water, and nutrients that your tissues and organs need to survive. (merckmanuals.com)
  • All tissues and organs are made of billions of different cells. (merckmanuals.com)
  • SUMMARY: Changes in the microcirculation of multiple tissues and organs have been implicated as a possible mechanism in physiological aging. (bvsalud.org)
  • Your liver is the largest solid organ in your body. (kidshealth.org)
  • The American Liver Foundation is the nation's largest non-profit organization focused solely on promoting liver health and disease prevention. (liverfoundation.org)
  • The human liver is an organ that has four lobes of varying sizes. (healthline.com)
  • The liver is a large organ in most vertebrates and therefore has a large demand for oxygen from the blood supply. (healthline.com)
  • The liver is shaped like a half-moon and is your body's largest solid organ. (healthline.com)
  • The liver, the body's largest solid organ, functions as a filtration system. (healthline.com)
  • The liver is divided into a large right lobe and a small left lobe. (healthline.com)
  • The tiny organs are constructed using Organovo's NovoGen Bioprinting platform, and as New Scientist explains, this 3D printer builds up over 20 layers of hepatocytes and stellate cells-two major types of liver cells. (inhabitat.com)
  • The researchers have not yet implanted a liver preserved using this new method into a human subject, but they say traditional standards of assessing liver viability indicate that this process will not negatively affect the organ. (cosmosmagazine.com)
  • Earlier, Camargo showed that manipulation of Yap1 in the mouse liver can increases the organ's size by four-fold. (vectorblog.org)
  • A small, pear-shaped sac located on the underside of the liver, the gallbladder varies in size, but rarely exceeds 4cm in diameter and 10cm in length. (cdc.gov)
  • This could lead to accumulation and potentially adverse reactions in critical organs such as liver, heart, and even brain, consistent with the hypothesis that ultrafine insoluble particles may play a role in the onset of cardiovas- cular diseases, as growing evidence from epidemiological studies suggests. (cdc.gov)
  • 1% of the deposited particles into secondary organs such as liver, spleen, heart, and brain was measured after systemic uptake from the lungs. (cdc.gov)
  • Chronic stress (CS) can contribute to dysfunction in several organs including liver and kidney. (bvsalud.org)
  • Thus, asymptomatic fibroids of smaller size were handled via observation, with an annual pelvic examination and/or transvaginal ultrasonography. (medscape.com)
  • Sacrocolpopexy (sacral colpopexy) is a surgical technique for repairing pelvic organ prolapse. (medscape.com)
  • The specific treatment approach is chosen in accordance with the type and degree of pelvic organ prolapse, as well as the severity of symptoms. (medscape.com)
  • The image below illustrates the Pelvic Organ Prolapse Quantification staging system. (medscape.com)
  • Prolapse staging according to the Pelvic Organ Prolapse Quantification staging system. (medscape.com)
  • Pelvic organ prolapse refers to the symptomatic descent of at least two parts of the vaginal wall-the anterior/posterior walls and the apex. (medscape.com)
  • Similar to abdominal hernias, pelvic organ prolapse can be considered a herniation of either pelvic or abdominal contents through a structural weakness in the pelvic floor. (medscape.com)
  • Symptoms of pelvic organ prolapse have been defined in a joint report from the International Urogynecological Association and International Continence Society as "a departure from normal sensation, structure, or function, experienced by the woman in reference to the position of her pelvic organs. (medscape.com)
  • The Pelvic Organ Prolapse Quantification (POPQ) system and the Baden-Walker system are two systems that can be used to evaluate the degree of prolapse. (medscape.com)
  • The ideal treatment option for terminally ill patients is organ transplantation. (frontiersin.org)
  • To take human organ generation via BC and transplantation to the next step, we reviewed current emerging organ generation technologies and the associated efficiency of chimera formation in human cells from the standpoint of developmental biology. (frontiersin.org)
  • Organ transplantation is the ultimate treatment option for patients suffering from refractory diseases. (frontiersin.org)
  • Depending on the patient's medical condition, a refractory disease patient also requires an on-time selective option, such as less invasive cellular therapy options or curative organ transplantation that can function immediately after transplantation. (frontiersin.org)
  • The demand for wearable artificial organs is on the rise owing to the increasing number of the geriatric populations prone to kidney failure and less cost of wearable artificial organs compare to organ transplantation. (grandviewresearch.com)
  • The size difference significantly increased the risk that ice crystals would start to spontaneously form, making the organ unusable for transplantation. (cosmosmagazine.com)
  • Both additives have been used in the cryogenic preservation of cells in the laboratory, the researchers say, but had not been used in the preservation of organs for transplantation. (cosmosmagazine.com)
  • The pipe organ in the main auditorium of the Boardwalk Hall in Atlantic City is the largest organ in the world. (sojo1049.com)
  • The pipe organ at boardwalk hall has an astounding 33,112 pipes. (sojo1049.com)
  • The big pipe organ took three years to build. (sojo1049.com)
  • There was significant damage to the pipe organ in 1944 when a hurricane flooded the Boardwalk Hall causing major damage to the blowers. (sojo1049.com)
  • The organ wasn't operating at full strength until September of 1998 when a grant of $1.17 million brought the pipe organ back into playable condition. (sojo1049.com)
  • The name is a combination of the words stalactite and pipe organ but in actuality, it is a percussion instrument. (wglt.org)
  • There's no, uh, great stalactite pipe organ store, so we can't go buy parts for it," Mayer said. (wglt.org)
  • Robert Koopmann, OSB and the rest of the members of the Saint John's Abbey have had to wait longer than expected to finally showcase the newly-expanded pipe organ in the Saint John's Abbey and University Church. (csbsju.edu)
  • Events kick off with the Solemn Blessing of the Expanded Holtkamp-Pasi Pipe Organ at 7 p.m. Saturday, Sept. 18. (csbsju.edu)
  • Friends of the Saenger (FOS) is proud to announce that our next project in our continuing effort to improve the Saenger Theatre is the complete restoration and enhancement of The Great Saenger Pipe Organ. (pensacolasaenger.com)
  • When finished, The Great Saenger Pipe Organ will rival any of the large theatre organs in the country. (pensacolasaenger.com)
  • After much research, FOS determined that we could restore and enhance The Great Saenger Pipe Organ for approximately $330,000. (pensacolasaenger.com)
  • This segment of All Things Considered on NPR highlights the pipe organ at the Paramount Theater in Seattle. (pensacolasaenger.com)
  • It was built in 1927 when the theater was built and the man who plays it does a great job of describing and demonstrating all the bells and whistles that are associated with organs like our very own Great Saenger Pipe Organ. (pensacolasaenger.com)
  • To make our pipe organ a world-class instrument, we need to add the following components. (pensacolasaenger.com)
  • A U.S. Natural Landmark featuring the world's only Stalacpipe Organ. (blueridgeparkway.org)
  • The Great Stalacpipe Organ spans 3.5 acres of the cave and is considered the world's largest musical instrument. (wglt.org)
  • This is the heart of The Great Stalacpipe Organ. (wglt.org)
  • Larry Moyer, center, who started working at the Caverns for 42 years as a teenager and is now the lead engineer of the organ.Two apprentices, Stephanie Beahm, right, and Ben Caton are both learning what they can from Moyer so that future generations may experience the enchanting sounds of the Great Stalacpipe Organ. (wglt.org)
  • Over the decades, Moyer has labored countless long nights tending to the Great Stalacpipe Organ for the enjoyment of visitors. (wglt.org)
  • Two younger apprentices, Stephanie Beahm and Ben Caton are both learning what they can from Moyer so that future generations may experience the enchanting sounds of the Great Stalacpipe Organ. (wglt.org)
  • Other important organs in this system include the bone marrow, spleen, thymus and gut-associated lymphoid tissue (GALT), which is the lymphatic tissue associated with the gastrointestinal (GI) tract. (petplace.com)
  • The spleen is the largest body of lymphatic system. (petplace.com)
  • The thymus is an organ that varies in size depending on the age of the individual. (petplace.com)
  • From what I have read (and my mothers gyn) doctors remove large cysts laproscopically often and some doctors remove ovaries and other organs because doing so takes less skill and time than trying to just take the cyst. (medhelp.org)
  • The material was significantly aggregated and unlike larger diameter multi-walled carbon nanotubes (MW), no translocation to systemic organs was detected. (cdc.gov)
  • World's largest series of music folios * Full-size books - large 9" x 12" format features easy-to-read, easy-to-play music * Accurate arrangements. (sheetmusicplus.com)
  • All transmitted from person to person has been raised after the carriers were asymptomatic, anti-HIV negative, and had reports of cluster outbreaks of PCP among solid-organ normal total lymphocyte and CD4+ cell counts. (cdc.gov)
  • Students can learn the names and functions of each part of the brain, build a human skeleton from a friendly pile of bones, organize the digestive organs, or take a narrated tour of the human heart. (educationworld.com)
  • Digestive diseases represent the third largest economic burden of illness in the United States. (cdc.gov)
  • To compare the functions of primary and secondary lymphoid organs. (pearson.com)
  • Camargo, born in Peru and named a Pew Scholar last year at the age of 33, has been interested in understanding what maintains organs at a specific size. (vectorblog.org)
  • It is a dark red organ that is supplied with numerous blood vessels. (petplace.com)
  • Taken alone, this is pretty extraordinary, but Organovo believes that in the future they will be able to create larger "livers" that can be used for transplant in humans-which means developing a technique to 3D print human-sized networks of blood vessels that will be capable of nourishing the entire organ. (inhabitat.com)
  • Harmonium , a hand-pumped organ, of the type used in South Asia, here used at a European jazz festival. (wikipedia.org)
  • Specific types of pump organ include the reed organ , harmonium, and melodeon. (wikipedia.org)
  • Assessment of generated aerosols show primarily micrometer-sized particles with some MW protrusions. (cdc.gov)
  • However, though BC is emerging as a potential organ transplant option, challenges regarding organ size scalability, immune system incompatibilities, long-term maintenance, potential evolutionary distance, or unveiled mechanisms between donor and host cells remain. (frontiersin.org)
  • As the lymph is carried from distant parts of the body, it is collected into larger and larger vessels until the vessels all converge in the chest and deposit the lymph in the large vein (cranial vena cava) leading to the right atrium of the heart. (petplace.com)
  • In this population, features of malignancy include large tumor size (weight greater than 400 grams and tumor size greater than 10.5 cm), vena cava invasion, confluent necrosis, higher mitotic rate (more than 15 mitoses per HPF), atypical mitoses, and invasion of adjacent soft tissue. (cap.org)
  • However, donor organs are in absolute shortage, and sadly, most patients die while waiting for a donor organ. (frontiersin.org)
  • The wearable artificial kidney segment is expected to grow at an exponential rate owing to the increasing incidence of kidney failure and the shortage of organ donors. (grandviewresearch.com)
  • Alongside the furniture-sized instruments of the west, smaller designs exist. (wikipedia.org)
  • This organ now takes its place alongside the great organs of Europe - many of which are also monastic organs. (csbsju.edu)
  • How much longer than the large intestine is the small intestine? (educationworld.com)
  • Hummingbirds are unique amongst birds because of their small size (2 - 20 g or 0.07 - 0.7 oz ), elevated average body temperature (~40° C or 104° F), and rapid heart rate (up to 1,260 beats per minute) (Johnsgard, 1983). (earthlife.net)
  • It is largest in young animals and shrinks to a very small size in the adult. (petplace.com)
  • Each key on the organ, when pressed, triggers a small electric hammer. (wglt.org)
  • Secular works were crafted to make the most of large palaces and small chambers. (abc.net.au)
  • Small (cue-sized) notes are provided for instruments which have a larger compass keyboard and are to be employed when available. (carsoncooman.com)
  • Before, there were a lot of experts who said, 'well this is amazing in small rats, but it will not work in human organs,' and now we have successfully scaled it up 200 times from rat to human livers using a combination of technologies. (cosmosmagazine.com)
  • Human cells vary in size, but all are quite small. (merckmanuals.com)
  • At half a millimeter deep by four millimeters wide, the livers will likely be used for medical tests, but Organovo hopes that they will soon produce full-sized livers that could do away with agonizing waits on long transplant lists. (inhabitat.com)
  • However, the technique was unsuccessful when applied to human livers, which are 200 times larger. (cosmosmagazine.com)
  • When it came back benign, he continued to remove organs - my other ovary, uterus and tubes. (medhelp.org)
  • [ 2 , 3 ] They are benign uterine tumors that increase in size and frequency as women age but revert in size postmenopausally. (medscape.com)
  • According to Reiter et al, no increased incidence in perioperative morbidity existed posthysterectomy in those women with a fibroid uterus larger than 12 weeks' gestational size compared to those women with a fibroid uterus smaller than 12 weeks' gestational size. (medscape.com)
  • [ 10 ] They concluded that hysterectomy for a large asymptomatic fibroid uterus may not be needed as a means of preventing increased operative morbidity associated with future growth, unless a sarcomatous change is observed. (medscape.com)
  • In patients who experience symptoms with fibroids, the symptoms are related to the size, location, and number of fibroids within the uterus. (medscape.com)
  • Kidneys The kidneys are bean-shaped organs that figure prominently in the urinary tract. (merckmanuals.com)
  • Larvae can cause inflammatory reactions in organs and tissue damage. (cdc.gov)
  • Luray Caverns - Eastern America's largest and most popular caverns. (blueridgeparkway.org)
  • Luray Caverns are home to the largest musical instrument in the world. (wglt.org)
  • Successfully Added Kids Electronic Piano Keyboard Electronic Organ Early Education Musical Instruments with Microphone 61 key to your Shopping Cart. (chinavasion.com)
  • This is similar to the organization of a piano where the longer, larger strings produce the lower frequency sounds. (bcm.edu)
  • Blood lead levels were positively correlated with family size ( r = 0.15) and negatively correlated with household area ( r = -0.18). (who.int)
  • Manufacturers in the industry are focused on biological replacement and organ repair that will function as a tissue-based artificial organ and mimics an organ's physiological function. (grandviewresearch.com)
  • Larger animals with defects in this organ-size widget also have overgrown body parts. (vectorblog.org)
  • Relatively larger defects can be reconstructed easily with local flaps, such as buccal mucosa, tongue, palate, and nasolabial flaps. (medscape.com)
  • A Palearctic species An organ pipe mud dauber adding to her nest in Virginia Nest underside Coville, Rollin E. (January 1981). (wikipedia.org)
  • This makes sense, but despite over a century of research on the evolution of brain size, there is still controversy, largely stemming from the fact that evidence for the expensive tissue hypothesis is based entirely on between species comparisons and correlations, with no empirical tests. (scientificamerican.com)
  • Rather than comparing species with bigger brain-to-body ratios to smaller-brained relatives, they exploited the natural variation of brain size in guppies ( Poecilia reticulata ). (scientificamerican.com)
  • Humans are one of the few surviving species with such a large brain to body size ratio. (sciencedaily.com)
  • Functional responses to environmental variation do not only depend on the genetic potential of a species to express different trait values, but can also be limited by characteristics, such as the timing of organ (pre-) formation, aboveground longevity or the presence of a storage organ. (springer.com)
  • No differences were found between species of syntropy, echogenicity and echotexture of the organs of the coelomic cavity. (scielo.br)
  • This group of butterflies includes some of the largest and most beautiful species, always among the favorites of collectors and curators ( Miller and Miller, 1976 ). (bioone.org)
  • America's fourth largest city is a great place to live, work and play. (bcm.edu)
  • Previously, uterine size (consisting of asymptomatic fibroids) equivalent to 12 weeks' gestation (280 g) had been the standard threshold for recommending a hysterectomy. (medscape.com)
  • They successfully created smarty-pants guppies that had brains about 9% larger than their counterparts through artificial selection. (scientificamerican.com)
  • The global wearable artificial organs market size was valued at USD 5.4 billion in 2019 and is expected to grow at a compound annual growth rate (CAGR) of 16.2% from 2020 to 2027. (grandviewresearch.com)
  • Technological advancement coupled with continuous investments in research and development for wearable artificial organs is also boosting the market growth. (grandviewresearch.com)
  • Major players in the industry are focusing on the development of wearable artificial organs for the disease that cannot be cured with alternative methods. (grandviewresearch.com)
  • Advancement in the field of genetic engineering, stem cell , microelectronics, nanotechnology, genomics , proteomics , artificial intelligence , and bioinformatics is creating new avenues for wearable artificial organs. (grandviewresearch.com)
  • The market for wearable artificial organs is moving from mechanical alternative towards real biological replacement. (grandviewresearch.com)
  • Increasing incidence of road accidence and a high number of permanent injuries are also creating demand for wearable artificial organs. (grandviewresearch.com)
  • The cochlear implant dominated the market for wearable artificial organs and accounted for a revenue share of 30.1% in 2019, owing to frequent product launches. (grandviewresearch.com)
  • Electronic wearable artificial organs dominated the market for wearable artificial organs and accounted for a revenue share of 69.6% in 2019, owing to technological advancement and increasing adoption of these devices. (grandviewresearch.com)
  • Females showed a positive correlation between body size and increased fecundity, which offers an explanation as to why the bias for increased female food provision and body size exists. (wikipedia.org)
  • They have the largest brain (4.2% of the total body weight), the largest heart and the largest breast and flight muscles (30% of its total body mass) in proportion to body size than any other bird (Long, 1997). (earthlife.net)
  • compared to their body size. (medlineplus.gov)
  • BWS is the most common overgrowth syndrome characterized by large organs and body size. (ggc.org)
  • Increasing demand and supply gap of organ donors coupled with the rising incidence of organ failure is driving the market. (grandviewresearch.com)
  • One of the most interesting evolutionary hypotheses about brain size is The Expensive Tissue Hypothesis . (scientificamerican.com)
  • CollPlant is a pioneering regenerative and aesthetics medicine company developing innovative technologies and products based on its plant-based collagen for tissue regeneration and organ manufacturing. (biospace.com)
  • The staggered approach, the researchers say, allows the tissue time to adjust and ensures the solution spreads throughout the organ more uniformly. (cosmosmagazine.com)
  • The supporting cells of the organ of Corti are not found immediately adjacent to the outer hair cells so that for most of the length of these cylindrically shaped cells are surrounded by a relatively large fluid filled space (Figure 6 provides a view of a row of outer hair cells). (bcm.edu)
  • The pump organ is a type of free-reed organ that generates sound as air flows past a vibrating piece of thin metal in a frame. (wikipedia.org)
  • The finer pump organs had a wider range of tones, and the cabinets of those intended for churches and affluent homes were often excellent pieces of furniture. (wikipedia.org)
  • When sound is transmitted to the inner ear the organ of Corti begins to vibrate up and down. (bcm.edu)
  • Throughout the cave, these hammers gently strike stalactites of various sizes, causing them to vibrate and give off a musical note. (wglt.org)
  • Or they can choose Anatomy Lessons to tour the human body organ-by-organ. (educationworld.com)
  • In this regard, emerging technologies of chimeric human organ production via blastocyst complementation (BC) holds great promise. (frontiersin.org)
  • In this review, we summarize the history of interspecies chimerism in various animal models to find hints for BC application and describe the challenges and prospects of utilizing BC for human organ generation. (frontiersin.org)
  • Human size breast implant, printed with Stratasys P3 3D printing technology and CollPlant's bioink. (biospace.com)
  • Based on these positive results, CollPlant is planning to initiate a follow-up, large-animal study in the second half of 2023 using commercial-size implants to support subsequent human studies and future product commercialization. (biospace.com)
  • A number of them - including wooden ones so large a slim adult can fit inside - were built on-campus in Collegeville in the Abbey's woodworking shop. (csbsju.edu)
  • In 2017, approximately 114,000 patients in the United States waited for an organ transplant ( Sykes and Sachs, 2019 ). (frontiersin.org)
  • Presently, in the United States, another person is added to an organ transplant list every 10 min, 17 people die each day while waiting for donor organs, and approximately 105,800 patients are waitlisted for an organ transplant according to the health resources and services administration (HRSA). (frontiersin.org)
  • According to the National Kidney Foundation, there are 121,678 people on the waiting list for organ transplants in the U.S. and of these approximately 100,791 people are waiting for a kidney transplant. (grandviewresearch.com)
  • when large numbers of embryonated eggs are ingested, larvae may be more likely to penetrate the central nervous system, causing neural larva migrans. (cdc.gov)
  • However, the clinical course often is more severe because, unlike Toxocara , Baylisascaris larvae are larger and continue to molt and increase in size, resulting in extensive reaction and damage in the CNS, heart, and other internal organs. (cdc.gov)
  • The ultrasound examination proved to be a safe, non-invasive and efficient technique for characterizing the organs of the coelomic cavity of snakes. (scielo.br)
  • In January 2023, CollPlant announced that it successfully completed a large-animal study for its 3D bioprinted regenerative breast implants. (biospace.com)
  • While the males seemed to gain no benefits from possessing larger noggins, the females with bigger brains were significantly better at the task. (scientificamerican.com)
  • The hummingbird has the largest heart in proportion to its body - and has the highest heartbeat rate. (earthlife.net)
  • Biology of the Heart The heart is a hollow organ made of muscle. (merckmanuals.com)
  • Our demonstration of a reduction in gut size and offspring number in the experimental populations selected for larger relative brain size provides compelling experimental evidence for the cost of increased brain size. (scientificamerican.com)
  • The number of pipes determine the size. (sojo1049.com)
  • Originally the organ was to house an amazing 43,000 pipes and cost $300,000 to build. (sojo1049.com)
  • The project - completed under the direction of renowned organ designer Martin Pasi - entailed adding nearly 3,000 new pipes to the instrument, which was built by Walter Holtkamp Sr. and dates back to when the church (designed by famed architect Marcel Breuer) was dedicated in 1961. (csbsju.edu)
  • Following the expansion, the organ now boasts over 6,000 pipes in all. (csbsju.edu)
  • In addition to restoring the console and pipes that have been hidden in the walls of the Saenger (some since 1925) we are going to greatly increase the size and capacity of the organ. (pensacolasaenger.com)
  • In this regard, whole organ generation via the BC approach holds great promise with a ready resource (livestock) for cellular therapies and as a radical treatment option for most terminal diseases. (frontiersin.org)
  • Metastatic tumors involving colon are rare, accounting for only 0.338% of all colorectal malignancies in a large multi-institutional study, when lymphoproliferative diseases, direct invasion, and mesenteric and peritoneal spreading are excluded [ 1 ]. (hindawi.com)
  • We believe these models will prove superior in their ability to provide predictive data for drug discovery and development, better than animal models or current cell models," explained Keith Murphy, Chairman and Chief Executive Officer at Organovo.The organs can be infected with diseases-and treated with medication-to run tests with more accurate results than one would receive from 2D cultures. (inhabitat.com)
  • Back in the early 1990s, scientists were looking to explain how brain size evolves. (scientificamerican.com)
  • Researchers from Uppsala University in Sweden were able to use their numerical abilities to test whether brain size affects intelligence in these simple fish. (scientificamerican.com)
  • The brain is a large organ and requires a lot of energy. (sciencedaily.com)
  • The largest sexual organ is the brain after all. (interracialdatingcentral.com)
  • The story began several years ago with the discovery of a size-control pathway known as Hippo - so named because its inactivation in fruit flies (in which it was initially discovered) led to growth of enormous tumors, oversized eyes and wings eight times normal size. (vectorblog.org)
  • More portable than pipe organs , free-reed organs were widely used in smaller churches and in private homes in the 19th century, but their volume and tonal range were limited. (wikipedia.org)
  • Over subsequent centuries, composers became sophisticated sound designers, as orchestras evolved and organs became intrinsic to the building of churches. (abc.net.au)
  • The hypothesis suggests that while brains are great and all, their extreme energetic cost limits their size and tempers their growth. (scientificamerican.com)