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  • Hepatic
  • Hepatic function should be monitored closely with both clinical and laboratory follow-up for at least several months in patients who discontinue lamivudine and are co-infected with HIV-1 and HBV. (nih.gov)
  • discontinue
  • HIV or HBV-infected women on lamivudine are warned to discontinue breastfeeding as this puts the baby at risk for HIV transmission and medication side effects. (wikipedia.org)
  • anti-viral
  • A better explanation of the data is that lamivudine continues to have a partial anti-viral effect even in the presence of the M184V mutation. (wikipedia.org)
  • hepatitis
  • Exacerbations of Hepatitis B: Severe acute exacerbations of hepatitis B have been reported in patients who are co-infected with hepatitis B virus (HBV) and human immunodeficiency virus (HIV-1) and have discontinued lamivudine. (nih.gov)
  • If you have HIV and hepatitis B, the hepatitis b virus can change while you take lamivudine oral solution. (drugs.com)
  • Lamivudine is a nucleoside reverse transcriptase inhibitor and works by blocking the HIV reverse transcriptase and hepatitis B virus polymerase. (wikipedia.org)
  • Long-term use of lamivudine leads to emergence of a resistant hepatitis B virus (YMDD) mutant. (wikipedia.org)
  • In hepatitis B, lamivudine resistance was first described in the YMDD (tyrosine-methionine-aspartate-aspartate) locus of the HBV reverse transcriptase gene. (wikipedia.org)
  • Long-term use of lamivudine can trigger a resistant hepatitis B virus (YMDD) mutant. (wikipedia.org)
  • Structurally similar to lamivudine, it is approved for the treatment of HIV and undergoing clinical trials for hepatitis B. Entecavir, also called ETV, is a guanosine analog used for hepatitis B under the trade name Baraclude. (wikipedia.org)
  • infection
  • Patients with HIV-1 infection should receive only dosage forms of lamivudine appropriate for treatment of HIV-1. (nih.gov)
  • safely
  • These highlights do not include all the information needed to use lamivudine safely and effectively. (nih.gov)
  • maintenance therapy
  • The purpose of this study is to evaluate the virological efficacy of maintenance therapy with atazanavir with ritonavir combined with lamivudine in treatment experienced HIV positive patients with full and stable virological suppression. (clinicaltrials.gov)
  • drug
  • Teva Pharmaceuticals and Lupin Ltd both filed abbreviated new drug applications (ANDAs) relating to the treatments of HIV using various combinations of abacavir, lamivudine and AZT, and challenging various patents. (wikipedia.org)
  • Other examples include 2-hydroxytetrahydrothiophene and the anti-HIV drug Lamivudine. (wikipedia.org)
  • drugs
  • A pancreas problem ( pancreatitis ) has happened in children taking lamivudine with or without other HIV drugs. (drugs.com)