• bipolar disorder
  • An international study led by University of Texas Southwestern Medical Center and University of California, Los Angeles researchers indicates that more than a dozen traits related to sleep, wake, and activity cycles associated with severe bipolar disorder appear to be inherited. (mdmag.com)
  • The research is the first large-scale delineation of sleep and activity traits in people with bipolar disorder and their relatives and the first genetic investigation of a large set of sleep and circadian measures in any human study. (mdmag.com)
  • We were able to identify 13 sleep and activity measures, most of which are inherited, that correlated with whether an individual had bipolar disorder," said Joseph Takahashi, PhD, Professor and Loyd B. Sands Distinguished Chair in Neuroscience and Howard Hughes Medical Institute Investigator at UT Southwestern. (mdmag.com)
  • adulthood
  • Fujita, 1962 ) and that immense efforts are currently invested worldwide in stem cell research and regenerative medicine, it comes as a surprise that cell cycle studies during adulthood, contrary to development, are extremely limited with only a handful addressing the diseased brain. (frontiersin.org)
  • These limitations, together with the fact that a significant proportion of NSC are quiescent, makes it remarkably difficult to assess cell cycle parameters during adulthood. (frontiersin.org)
  • correlate
  • As one factor fuelling interest in this area, short cell cycles were found to correlate with a higher proliferative potential of neural precursors at the cellular and tissue level and across phylogeny ( Borrell and Calegari, in press ). (frontiersin.org)
  • Secretions of various hormones, including renin, growth hormone, and prolactin, correlate positively with delta-wave activity, while secretion of thyroid-stimulating hormone correlates inversely. (wikipedia.org)
  • physiological
  • The basic rest-activity cycle (BRAC) is a physiological arousal mechanism in humans proposed by Nathaniel Kleitman, hypothesized to occur during both sleep and wakefulness. (wikipedia.org)
  • In this review, we briefly discuss the long journey of NSC research from embryonic development to adult homeostasis, aging and therapy with a specific focus on their quiescence and cell cycle length in physiological conditions and neurological disorders. (frontiersin.org)
  • Here we summarize our knowledge on cell cycle parameters of adult neural precursors in physiological and pathological conditions with particular attention to a new player in biomedicine, oligodendrocyte progenitors. (frontiersin.org)
  • adult
  • However, and despite a huge literature on embryonic neural precursors, very little is known about cell cycle parameters of adult neural, or any other somatic, stem cell. (frontiersin.org)
  • The standard figure given for the average length of the sleep cycle in an adult man is 90 minutes. (wikipedia.org)
  • years
  • After 18 years and nearly three complete orbits around the sun, Ulysses, the interplanetary space probe that provided scientists with a more complete understanding of the solar wind and the solar activity cycle, was turned off. (bu.edu)
  • Here we describe the walking and cycling activity of the cohorts in 1995-96 when they were interviewed for the third time and were aged about 24, 44 and 64 years, respectively. (strath.ac.uk)
  • This metallicity is given in term of the ratio of iron to hydrogen, as compared to the Sun. In the case of HR 1614, this ratio is about 90% higher than the Sun. The activity cycle for this star is 11.1 years in length. (wikipedia.org)
  • Sunspot activity cycles are about every eleven years, with some variation in length. (wikipedia.org)
  • Play media Solar cycles have an average duration of about 11 years. (wikipedia.org)
  • The level of solar activity beginning in the 1940s is exceptional - the last period of similar magnitude occurred around 9,000 years ago (during the warm Boreal period). (wikipedia.org)
  • The Sun was at a similarly high level of magnetic activity for only ~10% of the past 11,400 years. (wikipedia.org)
  • Fossil records suggest that the Solar cycle has been stable for at least the last 290 million years. (wikipedia.org)
  • For example, the cycle length during the early Permian is estimated to be 10.62 years. (wikipedia.org)
  • It was first thought that 28 cycles had spanned the 309 years between 1699 and 2008, giving an average length of 11.04 years, but recent research has showed that the longest of these (1784-1799) seems actually to have been two cycles, meaning that one of the two had to have lasted less than 8 years. (wikipedia.org)
  • Physical Activity
  • Walking and cycling are frequently promoted as modes of physical activity that are accessible to the whole population and yet little is known about the population prevalence of these activities. (strath.ac.uk)
  • That people often do not exhibit such sleep organization in daily life merely suggests that humans have the capacity (often with the aid of stimulants such as caffeine or increased physical activity) to overcome the propensity for sleep when it is desirable, or is required, to do so. (wikipedia.org)
  • Release of CRH from the hypothalamus is influenced by stress, physical activity, illness, by blood levels of cortisol and by the sleep/wake cycle (circadian rhythm). (wikipedia.org)
  • asleep
  • A difficulty for this theory is the fact that a long non-REM phase almost always precedes REM, regardless of when in the cycle a person falls asleep. (wikipedia.org)
  • Methods
  • There are many, often mutually controversial predictions , based on different methods, for the solar cycle 25, ranging from very weak to moderate magnitude. (wikipedia.org)
  • Research
  • Basic research during embryonic development has led to the identification of general principles governing cell cycle progression, proliferation and differentiation of mammalian neural stem cells (NSC). (frontiersin.org)
  • However, because nearly all manifestations are insensitive to polarity, the "11-year solar cycle" remains the focus of research. (wikipedia.org)
  • variations
  • The difference in the two cycles may indicate a change from faculae-dominated to star spot-dominated variations in luminosity. (wikipedia.org)
  • show
  • Can we show it in activity via a cycle? (ibm.com)
  • During the period of this cycle corresponding with REM, people tend to daydream more and show less muscle tone. (wikipedia.org)
  • The two halves of the 22-year cycle are not identical, typically alternating cycles show higher (lower) sunspot counts (the Gnevyshev-Ohl rule. (wikipedia.org)
  • Last
  • in the last 20 minutes when we feel dreamy and perhaps a little tired, while our body is being readied for the alert part of the following cycle. (wikipedia.org)
  • hours
  • Fragmentation of the rest-activity cycle was enhanced in a subgroup of persons having sleep for eight hours or less (P = 0.04) but reduced in those who preferred to sleep for more than eight hours per night (P = 0.05). (jcircadianrhythms.com)
  • state
  • It is radiating 98% of the solar luminosity from its photosphere at an effective temperature of 5,683 K. When observed from 1997 through 2000, the primary component appeared to be transitioning from a maunder minimum state to a state of cycling magnetic activity. (wikipedia.org)
  • different
  • Whether they are observing how evaporation causes puddles to dry up, or how plants put water into the atmosphere through transpiration, this resource engages children in exploring the different processes driving the hyrologic cycle. (lessonplanet.com)
  • Approach Victoria's diverse regions from a range of different perspectives as you cycle into towns and villages on purpose-built bike trails. (visitvictoria.com)
  • Bring
  • Then why not bring them to the lovely National Trust at Bovey Tracey on the edge of Dartmoor and have a Guided Cycle ride through the woods and parkland. (dartmoornt.org.uk)