Known adenoma acidophil. Medical search. Frequent questions

Electron microscopy revealed an undifferentiated, monomorphous adenoma with morphological features of an acidophil stem cell adenoma such as the presence of misplaced exocytoses, fibrous bodies and mitochondrial gigantism. (nih.gov)

[ 2 ] of which the great majority in this region are pituitary adenomas. (medscape.com)
Approximately 85% of masses from this region are pituitary adenomas, followed in incidence by craniopharyngioma, Rathke cleft cyst, meningioma, and metastasis. (cap.org)

The diagnosis of pituitary adenoma is usually straightforward on H&E stained sections, which readily identify the monomorphic adenoma cell population. (cap.org)

A third transcription factor, pituitary cell-restricted T box factor (Tpit), drives corticotroph adenomas but its antibody is not yet commercially available as an IHC marker. (cap.org)

Case report: ACTH-secreting pituitary carcinoma metastatic to the liver in a patient with a history of atypical pituitary adenoma and Cushing's disease. (uams.edu)

Lactotroph adenoma (prolactinoma) typically exhibits strong cytoplasmic prolactin immunoreactivity. (cap.org)

Note the delicate acinar pattern of a normal pituitary gland (left), in contrast with disruption of the normal reticulin network in adenoma (right) (Wilder reticulin stain). (medscape.com)

The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. (embl.de)

However, even when these hormonal stains are negative, positive staining for SF1 alone is sufficient to diagnose gonadotroph adenoma. (cap.org)
The majority of previously classified "null cell" adenomas - negative for all hormonal markers - are now recognized as SF1 - driven and therefore would be classified as gonadotroph adenomas. (cap.org)

Pituicytoma, granular cell tumor of the neurohypophysis, and spindle cell oncocytoma are nonneuroendocrine tumors arising in the posterior pituitary and occur much less frequently than pituitary adenomas. (medscape.com)

[ 3 ] Pituitary adenomas are uncommon in the pediatric population, but most tumors of childhood are clinically functioning adenomas and are thought to be more aggressive. (medscape.com)
Additionally, certain subtypes of adenoma have been shown to be more clinically aggressive in that they tend to be more invasive, have earlier recurrence, and are more resistant to treatment. (cap.org)

Furthermore, some adenoma cells were fusiform with long cytoplasmic processes resembling thyrotropes. (nih.gov)

Adenomas driven by the transcription factor SF1, which are exclusively of the gonadotroph type, are a common subtype encountered by the surgical pathologist. (cap.org)
Treatment is mainly surgical (transfenoidal adenectomy or hypophysectomy of the acidophil adenoma is the treatment of choice. (canestar.com)

Histology of the pituitary lesion showed a typical eosinophilic adenoma which only secreted GH when tested with specific immunostain. (nel.edu)

In the 2017 World Health Organization Classification of Tumours of Endocrine Organs , pituitary adenomas remain classified by hormone expression as assessed by IHC staining. (cap.org)

When apoplexy occurs in functioning adenomas, it may cause spontaneous remission. (nel.edu)

However, classification based upon the driving transcription factor for each adenoma subtype is emerging as an additional method for classification. (cap.org)

After the five years follow-up magnetic resonance imagining showed reduction of the adenoma size (17 × 12 mm) was significant. (nel.edu)

Acidophil cell List of human cell types derived from the germ layers Bassetti, M. (wikipedia.org)
This undifferentiated, monomorphous GH/TSH-secreting pituitary adenoma represents an entity that is unusual both in its ultrastructural features and clinical manifestations suggesting a cytogenesis from an early, undifferentiated stem cell. (nih.gov)

We presented a case with a 54 × 40 × 40 mm pituitary adenoma and optic chiasmatic compression with left sphenoid sinus invasion. (nel.edu)
Orbital invasion by ACTH-secreting pituitary adenomas. (uams.edu)

Specimens of the adenoma tissue obtained at autopsy confirmed the previous findings with the exception of positive immunostaining for TSH which was found in less than 1% of the adenoma cells. (nih.gov)

For pituitary adenomas, transsphenoidal surgery is usually considered the first line of treatment, followed by medical therapy for residual disease. (medscape.com)

The former "silent type 3 adenoma" is now reclassified as Pit-1 positive plurihormonal adenoma. (cap.org)

[ 2 ] Incidental adenomas can be found in nearly 10% of autopsied patients. (medscape.com)

After clinical evaluation a giant GH/TSH-secreting pituitary adenoma was diagnosed. (nih.gov)

In this section the general characteristics of pituitary adenomas are discussed, followed by separate sections on subtypes of pituitary adenomas, pituitary neuroendocrine tumors grading, and pituitary carcinomas. (medscape.com)

For the purpose of this review, only the more common lactotroph and somatotroph adenomas will be addressed. (cap.org)