Von Hippel-Lindau Tumor Suppressor Proteinvon Hippel-Lindau DiseasePancreatic CystHypoxia-Inducible Factor 1, alpha SubunitKidney NeoplasmsCarcinoma, Renal CellProcollagen-Proline DioxygenaseTumor Suppressor Protein p53Nobel PrizeUbiquitin-Protein LigasesTumor Suppressor ProteinsGenes, Tumor SuppressorHemangioblastomaRho FactorTumor Suppressor Protein p14ARFRetinoblastoma ProteinCell Line, TumorProto-Oncogene Proteins c-mdm2Protein-Serine-Threonine KinasesMutationvon Willebrand FactorMolecular Sequence DataProtein BindingApoptosisNuclear ProteinsTransfectionGenes, p53Phosphatidylinositol 3-KinasesCell LineGene Expression Regulation, NeoplasticDNA-Binding ProteinsProto-Oncogene ProteinsCell CycleTranscription FactorsNeurofibromin 2Signal TransductionPhosphorylationTumor Cells, CulturedProtein KinasesAdenomatous Polyposis Coli ProteinBase SequenceAmino Acid SequenceCell Cycle ProteinsCyclin-Dependent Kinase Inhibitor p21Cyclin-Dependent Kinase Inhibitor p16MAP Kinase Signaling SystemPromoter Regions, GeneticPTEN PhosphohydrolaseCell ProliferationGenes, SuppressorCell Transformation, NeoplasticCell DivisionBlotting, WesternProtein Structure, TertiaryRNA, MessengerTranscription, GeneticCyclinsDNA DamageDown-RegulationProteinsLigasesCyclin-Dependent KinasesNeoplasm ProteinsNeoplasmsBinding SitesTranscriptional ActivationRepressor ProteinsE2F Transcription FactorsRecombinant Fusion Proteinsvon Willebrand DiseasesCells, CulturedCarrier ProteinsHeLa CellsTumor Markers, BiologicalGene Expression RegulationProtein Kinase InhibitorsCalcium-Calmodulin-Dependent Protein KinasesFibroblastsRNA, Small InterferingGene SilencingRNA InterferenceReverse Transcriptase Polymerase Chain ReactionCell NucleusCell HypoxiaE2F1 Transcription FactorIntracellular Signaling Peptides and ProteinsRecombinant ProteinsSuppressor of Cytokine Signaling ProteinsGene DeletionSuppression, GeneticDNA PrimersModels, BiologicalTranscription Factor DP1PhosphoproteinsTrans-ActivatorsDNA MethylationLoss of HeterozygosityOncogene Proteins, Viralsrc-Family KinasesMembrane Proteins