• distal convol
  • Gross J.B, Imai M, and Kokko J. P. A functional comparison of the cortical collecting tubule and the distal convoluted tubule. (journalijar.com)
  • Close to the loop of Henle and in the distal convoluted tubule of the nephron where much glucose has been reabsorbed into the bloodstream, SGLT1 transporters are found. (wikipedia.org)
  • protein
  • The localization and transporting properties of a kidney protein homologous to human erythrocyte protein CHIP28 was evaluated. (rupress.org)
  • The cDNA encoding rat kidney protein CHIP28k was isolated from a rat renal cortex cDNA library. (rupress.org)
  • These results indicate that CHIP28k is a major and highly selective water transporting protein in the kidney proximal tubule and thin descending limb of Henle, but not collecting duct. (rupress.org)
  • Here, we investigated the effects of PPAR alpha and CP on expression and enzyme activity of kidney lipoprotein lipase (LPL) as well as on expression of angiopoietin protein-like 4 (Angptl4), glycosylphosphatidylinositol-anchored-HDL-binding protein (GPIHBP1), and lipase maturation factor 1 (Lmf1), which are recognized as important proteins that modulate LPL activity. (diva-portal.org)
  • In summary, a PPAR alpha ligand ameliorates CP-mediated nephrotoxicity by increasing LPL activity via increased expression of GPHBP1 and Lmf1 and by reducing expression of Angptl4 protein in the proximal tubule. (diva-portal.org)
  • Casts are held together by a protein released by the kidney. (smrtx.com)
  • Some of the muscle breakdown products, such as the protein myoglobin, are harmful to the kidneys and may lead to kidney failure. (wikipedia.org)
  • urinary
  • Casts and cellular debris originate from higher up in the urinary tract, such as in the kidneys. (smrtx.com)
  • These are material shed from kidney cell lining due to injury or inflammation and travel down through the urinary tubes. (smrtx.com)
  • Result: Under the light microscope, the kidney in experimental group show the many anatomical changes as increase in Wight, elongated and increase in width, and showed many histological changes as a glomerular enlargement with decrease of urinary space and dilation in proximal and distal tubule. (journalijar.com)
  • The glomerular filtrate leaves the Bowman's capsule at the renal tubule at the urinary pole. (wikipedia.org)
  • calcium oxalate
  • Triamterene can also cause kidney stones through direct crystallization or by seeding calcium oxalate stones. (wikipedia.org)
  • Many metal ions form insoluble precipitates with oxalate, a prominent example being calcium oxalate, the primary constituent of the most common kind of kidney stones. (wikipedia.org)
  • An estimated 80% of kidney stones are formed from calcium oxalate. (wikipedia.org)
  • reabsorption
  • Reabsorption occurs in the renal tubules and is either passive, due to diffusion, or active, due to pumping against a concentration gradient. (wikipedia.org)
  • Some of the hormones which signal the tubules to alter the reabsorption or secretion rate, and thereby maintain homeostasis, include (along with the substance affected) antidiuretic hormone (water), aldosterone (sodium, potassium), parathyroid hormone (calcium, phosphate), atrial natriuretic peptide (sodium) and brain natriuretic peptide (sodium). (wikipedia.org)
  • cortex
  • the increase in Pf with mRNA from cortex, but not kidney papilla, was blocked by coinjection with excess antisense CHIP28k cRNA. (rupress.org)
  • cellular
  • The data show that our model could reproduce ischemically induced cell swelling and characterized the response at the cellular level of tubules to different components of preservation solutions. (ebscohost.com)
  • Therapeutic
  • Our results indicate that targeting of the ADAM17 pathway represents a therapeutic target for human kidney fibrosis. (jci.org)
  • functional
  • In this video, see how the Wyss Institute team has advanced bioprinting to the point of being able to fabricate a functional subunit of a kidney. (harvard.edu)
  • concentration
  • Exogenous cyclic 3',5'-AMP (cAMP) and substances known to increase the intracellular concentration of this nucleotide (isoproterenol, theophylline, noradrenaline, lactate) were shown to inhibit the transport of fluorescein (a weak organic acid) into the rat renal proximal tubules at 20 degrees C. Carbacholine decreasing intracellular cAMP concentration stimulated the transport. (semanticscholar.org)
  • cell
  • The cell line was derived from the kidney of an adult female North American opossum (Didelphis virginiana). (wikipedia.org)
  • indicate
  • The data indicate that an isosmolar, phosphate-buffered, sucrose solution prevented tubule swelling more effectively than Euro-Collins, hyperosmolar citrate, or University of Wisconsin solutions that are in routine clinical use. (ebscohost.com)
  • water
  • As a result, there is a change in the activity of the potassium ion (K+) channels that changes the transepithelial transport of solutes and water in the kidney. (wikipedia.org)