• hyaline
  • In the kidneys, as a result of benign arterial hypertension, hyaline (pink, amorphous, homogeneous material) accumulates in the walls of small arteries and arterioles, producing the thickening of their walls and the narrowing of the arterial openings, a process known as arteriolosclerosis. (wikipedia.org)
  • protein
  • The localization and transporting properties of a kidney protein homologous to human erythrocyte protein CHIP28 was evaluated. (rupress.org)
  • The cDNA encoding rat kidney protein CHIP28k was isolated from a rat renal cortex cDNA library. (rupress.org)
  • These results indicate that CHIP28k is a major and highly selective water transporting protein in the kidney proximal tubule and thin descending limb of Henle, but not collecting duct. (rupress.org)
  • Here, we investigated the effects of PPAR alpha and CP on expression and enzyme activity of kidney lipoprotein lipase (LPL) as well as on expression of angiopoietin protein-like 4 (Angptl4), glycosylphosphatidylinositol-anchored-HDL-binding protein (GPIHBP1), and lipase maturation factor 1 (Lmf1), which are recognized as important proteins that modulate LPL activity. (diva-portal.org)
  • In summary, a PPAR alpha ligand ameliorates CP-mediated nephrotoxicity by increasing LPL activity via increased expression of GPHBP1 and Lmf1 and by reducing expression of Angptl4 protein in the proximal tubule. (diva-portal.org)
  • Casts are held together by a protein released by the kidney. (smrtx.com)
  • Some of the muscle breakdown products, such as the protein myoglobin, are harmful to the kidneys and may lead to kidney failure. (wikipedia.org)
  • The distal tubules of the kidneys secrete large amounts of uromucoid (Tamm-Horsfall protein). (wikipedia.org)
  • rats
  • Increased fatty acid (FA) synthesis enzymes and triglyceride deposition correlated with increased profibrotic factors were found in the kidney in diabetes in rats ( 4 ) and mice ( 5 ). (diabetesjournals.org)
  • reabsorption
  • Reabsorption occurs in the renal tubules and is either passive, due to diffusion, or active, due to pumping against a concentration gradient. (wikipedia.org)
  • Some of the hormones which signal the tubules to alter the reabsorption or secretion rate, and thereby maintain homeostasis, include (along with the substance affected) antidiuretic hormone (water), aldosterone (sodium, potassium), parathyroid hormone (calcium, phosphate), atrial natriuretic peptide (sodium) and brain natriuretic peptide (sodium). (wikipedia.org)
  • urinary
  • Urinary casts are tiny tube-shaped particles made up of white blood cells, red blood cells, or kidney cells. (smrtx.com)
  • Casts and cellular debris originate from higher up in the urinary tract, such as in the kidneys. (smrtx.com)
  • These are material shed from kidney cell lining due to injury or inflammation and travel down through the urinary tubes. (smrtx.com)
  • Result: Under the light microscope, the kidney in experimental group show the many anatomical changes as increase in Wight, elongated and increase in width, and showed many histological changes as a glomerular enlargement with decrease of urinary space and dilation in proximal and distal tubule. (journalijar.com)
  • The glomerular filtrate leaves the Bowman's capsule at the renal tubule at the urinary pole. (wikipedia.org)
  • fatty
  • Peroxisome proliferator-activated receptor-alpha (PPAR alpha) activation attenuates cisplatin (CP)-mediated acute kidney injury by increasing fatty acid oxidation, but mechanisms leading to reduced renal triglyceride (TG) accumulation could also contribute. (diva-portal.org)
  • In atheroembolic kidney disease, tiny pieces of hard fatty material travel through the bloodstream, becoming emboli (atheroemboli). (merckmanuals.com)
  • cortex
  • the increase in Pf with mRNA from cortex, but not kidney papilla, was blocked by coinjection with excess antisense CHIP28k cRNA. (rupress.org)
  • ureteric
  • Bailey R. R. and Rollest G. L. Kidney length and ureteric dilation in the puerperium. (journalijar.com)
  • During kidney ontogenesis, a reciprocal induction of the ureteric bud epithelium and nephrogenic mesenchyme occurs. (wikipedia.org)
  • found
  • However, they are nonspecific and may be found in people with many different kidney diseases. (smrtx.com)
  • decrease
  • citation needed] In this situation, the kidney supplied blood by the narrowed renal artery suffers from inadequate blood flow, which in turn causes the size of the kidneys to decrease. (wikipedia.org)
  • sodium
  • Liddle syndrome is a rare hereditary disorder in which the collecting tubules of the kidneys excrete potassium but retain too much sodium and water, leading to high blood pressure. (merckmanuals.com)
  • cell
  • The data show that our model could reproduce ischemically induced cell swelling and characterized the response at the cellular level of tubules to different components of preservation solutions. (ebscohost.com)