• Estrogen and progesterone have their respective hormone receptors, whereas allopregnanolone acts via the GABA(A) receptor. (researchgate.net)
  • 5-MT acts as a full agonist at the 5-HT 1 , 5-HT 2 , 5-HT 4 , 5-HT 6 , and 5-HT 7 receptors. (cloudfront.net)
  • In adults, an activation of the GABA-A receptor leads to an inward flow of chloride ions. (researchgate.net)
  • Estrogen alone, or in combination with progesterone, affects the brain serotonin system differently in different parts of the brain, which can at least partly explain the opposite effects on mood of those hormones. (researchgate.net)
  • Thus, certain subtypes will be able to influence the function of the brain area where the receptor is located [38]. (researchgate.net)