OrganismsDiseasesChemicals and DrugsGeographicals
ScabiesSarcoptes scabieiOnchocerciasisPermethrinFilaricidesAntinematodal AgentsIvermectinLice InfestationsAcaricidesAnthelminticsAntiparasitic AgentsSimuliidaeSkin Diseases, ParasiticLindaneInsecticidesMicrofilariaLoiasisStrongyloideaMite InfestationsAlbendazoleScalp DermatosesNorthern TerritoryLoaHydroxyzineElephantiasis, FilarialReceptors, Purinergic P2X4PyodermaOnchocerciasis, OcularStrongyloidiasisDiethylcarbamazinePediculusStrongyle Infections, EquineTyrosine Decarboxylase
SarcoptesInfestationMiteStromectolOral ivermectinDosesLicePermethrinHominisCalled crusted scabies or Norwegian scabiesMasses of scabies faecesDeveloped to treat scabiesBurrowsControl of scabiesInfestationsInfectionClinicallyCases of scabiesCrusted scabies oftenTreat crusted scabiesAntiparasitic drug IvermectinDoseAlbendazoleType of scabiesSource of scabiesOutbreaks of scabiesEffect of ivermectinSafety of ivermectinPatients with scabiesLindaneCauses scabiesDiagnose scabiesPrevalenceInfectionsRiver blindnessStrongyloidiasisParasitesHumansSymptomsItchy skinDiagnosisParasiteAllergicPreventing COVID-19Mites that causeParasitic diseaseTreatmentsTopicalTabletsDrugsCuniculiOnchocerciasisCoronavirusSevereNorwegianInfectsUsually spreadsWorld Health OrganTypicallyEndemicTreatmentIntenseTreatsPasteDogsDrugEfficacyInhibits
Sarcoptes14
Infestation8
  • A readily treatable infestation, scabies remains common primarily because of diagnostic difficulty, inadequate treatment of patients and their contacts, and improper environmental control measures. (medscape.com)
  • Bacterial skin infection (impetigo) frequently complicates scabies infestation in these settings. (acentds.org)
  • Less commonly, scabies infestation can happen through the sharing of clothes and bedding. (emedicinehealth.com)
  • If the person has never been exposed to scabies before, he or she may not show symptoms until 4 to 6 weeks after the initial infestation. (emedicinehealth.com)
  • Scabies causes substantial morbidity because of unbearable itch, secondary infection, post-infective complications such as glomerulonephritis [2-4], and the high risk of spreading the infestation to close contacts. (who.int)
  • Ivermectin is also sometimes used to treat certain other roundworm infections, head or pubic lice infestation, and scabies (itchy skin condition caused by infestation with small mites that live under the skin). (medlineplus.gov)
  • Scabies is a parasitic skin infestation caused by mites. (msdmanuals.com)
  • Male soldiers reporting sick to the above- ity because of unbearable itch, secondary mentioned hospitals with symptoms and infection, post-infective complications such signs clinically suggestive of scabies were as glomerulonephritis [ 2-4 ], and the high interviewed in detail and examined thor- risk of spreading the infestation to close oughly. (who.int)
Mite13
  • Direct transmission of conventional scabies occurs after prolonged skin-to-skin contact with a person infested with the mite. (cdc.gov)
  • Burrows, caused by the female scabies mite tunneling just beneath the surface of the skin, are sometimes seen. (cdc.gov)
  • Although finding mites, mite eggs, or scybala (mite feces) under the microscope can confirm the diagnosis of scabies, microscopic identification of mites is far less sensitive than clinical diagnosis. (cdc.gov)
  • Because of their heavy mite burden, patients with crusted scabies may require repeated applications of topical scabicides or treatment that simultaneously uses oral ivermectin and a topical agent, such as permethrin. (medscape.com)
  • Permethrin kills the scabies mite and eggs. (cdc.gov)
  • This works for scabies, a mite related to ticks. (halfbakery.com)
  • dog scabies mite). (newworldencyclopedia.org)
  • cuniculi is the rabbit scabies mite. (newworldencyclopedia.org)
  • Scabies is caused by a mite-like insect that is so tiny it is not visible with the naked eye. (vetinfo.com)
  • Scabies spreads (transmitted) through skin-to-skin contact with an infested person who carries the mite. (emedicinehealth.com)
  • Theoretically, a person can get scabies from touching something that the mite is on, but that is not a major mode of transmission. (emedicinehealth.com)
  • What Is the Life Cycle of the Scabies Mite? (emedicinehealth.com)
  • The life cycle of the scabies mite starts when the female tunnels (burrows) into the skin and deposits her eggs. (emedicinehealth.com)
Stromectol4
  • Ivermectin Brand name product: Stromectol* Ivermectin is an oral antiparasitic agent approved for the treatment of worm infestations. (cdc.gov)
  • Ivermectin+Paste+Dose+For+Chickens+������+www.Stromectol Ivermectin.com+������+Ivermectin+Treat+Scabies+In+Dogs? (orkla.com)
  • There are currently no open positions matching " ????+Ivermectin+Paste+Dose+For+Chickens+������+www.Stromectol-Ivermectin.com+������+Ivermectin+Treat+Scabies+In+Dogs? (orkla.com)
  • ivermectin (stromectol). (nanos.jp)
Oral ivermectin6
  • Both head lice and pubic lice can be treated with oral ivermectin, an ivermectin lotion applied directly to the affected area, or various other insecticides. (wikipedia.org)
  • Oral ivermectin should be considered for patients who have failed treatment with or who cannot tolerate FDA-approved topical medications for the treatment of scabies. (cdc.gov)
  • If used for classic scabies, two doses of oral ivermectin (200µg/kg/dose) should be taken with food, each approximately one week apart. (cdc.gov)
  • Oral ivermectin (200µg/kg/dose) should be taken with food. (cdc.gov)
  • Fewer treatment failures occurred by day seven with oral ivermectin compared with placebo in one small trial (55 participants). (cochrane.org)
  • Topical permethrin appeared more effective than oral ivermectin (140 participants, 2 trials), topical crotamiton (194 participants, 2 trials), and topical lindane (753 participants, 5 trials). (cochrane.org)
Doses11
  • For severe "crusted scabies", where the parasite burden is orders of magnitude higher than usual, the U.S. Centers for Disease Control and Prevention (CDC) recommends up to seven doses of ivermectin over the course of a month, along with a topical antiparasitic. (wikipedia.org)
  • Ivermectin is considered relatively free of toxicity in standard doses (around 300 µg/kg). (wikipedia.org)
  • Protocol for a cluster-randomised non-inferiority trial of one versus two doses of ivermectin for the control of scabies using a mass drug administration strategy (the RISE study). (acentds.org)
  • Villages will be randomly allocated to receive either one dose or two doses of ivermectin-based MDA in a 1:1 ratio. (acentds.org)
  • The primary objective of the study is to determine if ivermectin-based MDA with one dose is as effective as MDA with two doses in reducing the prevalence of scabies after 12 months. (acentds.org)
  • Some patients need only to take one dose, but many need to take two or three doses to cure scabies. (aad.org)
  • Taking large doses of ivermectin is dangerous. (news-medical.net)
  • Dr. McElyea said patients are packing his eastern and southeastern Oklahoma hospitals after taking ivermectin doses meant for a full-sized horse, because they believed false claims the horse de-wormer could fight COVID-19. (abovetopsecret.com)
  • It looks like some doctors are prescribing oral doses of ivermectin for scabies, but it's an off label use for the drug. (metafilter.com)
  • If you are taking ivermectin to treat onchocerciasis, additional doses 3, 6, or 12 months later may be necessary to control your infection. (medlineplus.gov)
  • If your infection has not cleared, your doctor will probably prescribe additional doses of ivermectin. (medlineplus.gov)
Lice6
  • Approved for human use in 1987, today it is used to treat infestations including head lice, scabies, river blindness (onchocerciasis), strongyloidiasis, trichuriasis, ascariasis and lymphatic filariasis. (wikipedia.org)
  • Also approved to treat head lice, this is a newer treatment for scabies. (aad.org)
  • Ivermectin is approved for human use to treat infections caused by some parasitic worms and head lice and skin conditions like rosacea. (news-medical.net)
  • Ivermectin is an approved drug to treat parasitic conditions, such as rosacea, head lice, and scabies. (news-medical.net)
  • Eventually without showers, washing, and proper hygiene, the body can get lice or scabies. (captainsjournal.com)
  • An additional benefit of these medications is their simultaneous effectiveness against other well-entrenched diseases of the tropics and subtropics, such as intestinal worms, lice and scabies. (who.int)
Permethrin12
Hominis3
  • They further reported that this variety penetrates the human skin, but does not form burrows, which is in contrast to typical S. scabiei infections of preferred hosts, such as with variety hominis affecting humans. (newworldencyclopedia.org)
  • hominis ) that burrows into the skin causes scabies. (emedicinehealth.com)
  • hominis ) that is less than 0.5 mm long causes scabies. (emedicinehealth.com)
Called crusted scabies or Norwegian scabies1
  • In people who have poor immune systems or who are malnourished, scabies can cause a syndrome called 'crusted scabies' or 'Norwegian scabies,' which is highly contagious and is associated with skin thickening and a scaly rash. (emedicinehealth.com)
Masses of scabies faeces2
  • It is confirmed by the demonstration of mites, eggs, or scybala (black or brown football-shaped masses of scabies faeces) on microscopic examination [6]. (who.int)
  • It is con- soldiers reporting to dermatology outpatient firmed by the demonstration of mites, eggs, departments of these hospitals with unre- or scybala (black or brown football-shaped lated dermatological problems, for example masses of scabies faeces) on microscopic vitiligo, herpes zoster, acne vulgaris, psoria- examination [ 6 ]. (who.int)
Developed to treat scabies1
  • Various drugs have been developed to treat scabies, and herbal and traditional medicines are also used. (cochrane.org)
Burrows2
  • The diagnosis of scabies can often be made clinically in patients with a pruritic rash and characteristic linear burrows. (medscape.com)
  • Symptoms and signs of scabies on the skin vary and may include short, linear, or nodular 'burrows' between the fingers, tiny red bumps and blisters on the skin, or a widespread, crusted rash . (emedicinehealth.com)
Control of scabies1
  • ABSTRACT Being a preventable disease, good control of scabies can be achieved by identification of risk factors. (who.int)
Infestations2
  • In fact, the term "7-year itch" was first used with reference to persistent, undiagnosed infestations with scabies (see the image below). (medscape.com)
  • Ivermectin is a medication that is used to treat parasite infestations. (abovetopsecret.com)
Infection8
  • Ivermectin is also used to treat infection with parasitic arthropods. (wikipedia.org)
  • These lesions result from scratching, secondary infection, and/or the host's immune response against the scabies mites and their products. (medscape.com)
  • Scabies is a parasitic infection of the skin. (cochrane.org)
  • The global prevalence of scabies is estimated at 300 million cases, but the level of infection varies between countries and communities. (cochrane.org)
  • Ivermectin is not clinically proven for the treatment of viral infection. (reliablerxpharmacy.com)
  • How do you treat an infection naturally ivermectin tablets? (unsg.org)
  • Ivermectin does not kill the adult worms that cause onchocerciasis and therefore it will not cure this type of infection. (medlineplus.gov)
  • If you are taking ivermectin to treat strongyloidiasis, you will need to have a stool exam at least three times during the first 3 months after your treatment to see if your infection has cleared. (medlineplus.gov)
Clinically3
  • Scabies is diagnosed clinically. (cdc.gov)
  • Clinically, crusted scabies often is mistaken for psoriasis, but can be accurately diagnosed by using skin scrapings because of the high number of mites in the sores. (cdc.gov)
  • PATIENTS AND METHODS: Scabies cases, which were clinically diagnosed between January 2016 and December 2020 in our hospital, were retrospectively screened, and 3,027 cases were detected. (bvsalud.org)
Cases of scabies2
Crusted scabies often1
  • Scabies that covers much of the body and crusted scabies often require stronger medicine. (aad.org)
Treat crusted scabies1
Antiparasitic drug Ivermectin1
  • The FDA's Center for Veterinary Medicine has recently become aware of increased public visibility of the antiparasitic drug ivermectin after the announcement of a research article that described the effect of ivermectin on SARS-CoV-2 in a laboratory setting. (medlineplus.gov)
Dose4
  • For most scabies cases, ivermectin is used in a two dose regimen: a first dose kills the active mites, but not their eggs. (wikipedia.org)
  • We designed the Regimens of Ivermectin for Scabies Elimination (RISE) trial to investigate whether one-dose MDA may be as effective as two-dose MDA in controlling scabies in high-prevalence settings. (acentds.org)
  • Secondary objectives include the effect of ivermectin-based MDA on impetigo prevalence after 12 and 24 months, the prevalence of scabies at 24 months after the intervention, the impact on presentation to health facilities with scabies and impetigo, and the safety of one-dose and two-dose MDA. (acentds.org)
  • Ivermectin Pour-On (generic) for Cattle applied at the recommended dose level of 500 mcg/kg is indicated for the effective control of these parasites. (revivalanimal.com)
Albendazole3
Type of scabies2
Source of scabies2
  • Animals are not a source of scabies. (cdc.gov)
  • Unless your dog has had direct contact with your neighbor it is highly unlikely your neighbor would be a source of scabies for your dog. (vetinfo.com)
Outbreaks of scabies2
  • This is the only way to prevent new outbreaks of scabies weeks later. (aad.org)
  • In the U.S., there were outbreaks of scabies in 10 schools in Texas and in hospital workers in Charlotte, N.C., in 2015. (emedicinehealth.com)
Effect of ivermectin2
  • erdafitinib will increase the level or effect of ivermectin by P-glycoprotein (MDR1) efflux transporter. (medscape.com)
  • clarithromycin will increase the level or effect of ivermectin by P-glycoprotein (MDR1) efflux transporter. (medscape.com)
Safety of ivermectin2
  • In children under the age of five or those who weigh less than 15 kilograms (33 pounds), there is limited data regarding the efficacy or safety of ivermectin, though the available data demonstrate few adverse effects. (wikipedia.org)
  • The safety of ivermectin in children weighing less than 15 kg and in pregnant women has not been established. (cdc.gov)
Patients with scabies3
  • Nodules occur in 7-10% of patients with scabies, particularly young children. (medscape.com)
  • [ 4 ] In addition, elevated immunoglobulin E (IgE) titers and eosinophilia may be demonstrated in some patients with scabies. (medscape.com)
  • During the 3-month period February 2006-April 2006 we carried out a case-control study on 200 patients with scabies and 200 controls to identify risk factors for scabies among male soldiers in Pakistan. (who.int)
Lindane1
  • Although FDA-approved for the treatment of scabies, lindane is not recommended as a first-line therapy. (cdc.gov)
Causes scabies2
Diagnose scabies3
  • How do dermatologists diagnose scabies? (aad.org)
  • A dermatologist can often diagnose scabies by visually examining a patient's skin from head to toe. (aad.org)
  • Doctors diagnose scabies by examining the itchy areas and sometimes by looking at skin scrapings under a microscope. (msdmanuals.com)
Prevalence1
Infections3
  • Primary care providers or pediatricians treat the majority of uncomplicated scabies infections. (emedicinehealth.com)
  • Scientists are finding that ivermectin-an oral drug that treats scabies, parasitic infections, river blindness, and rosacea in humans-is also effective in treating COVID-19. (theepochtimes.com)
  • This is available as an oral tablet, cream, or lotion and treats parasitic infections in the intestinal tract, eyes, or skin, including scabies and many types of worms. (medicalnewstoday.com)
River blindness1
  • For river blindness (onchocerciasis) and lymphatic filariasis, ivermectin is typically given as part of mass drug administration campaigns that distribute the drug to all members of a community affected by the disease. (wikipedia.org)
Strongyloidiasis1
Parasites4
  • Ivermectin is used to treat human diseases caused by roundworms and a wide variety of external parasites. (wikipedia.org)
  • Ivermectin is FDA-approved for use in animals for prevention of heartworm disease in some small animal species, and for treatment of certain internal and external parasites in various animal species. (medlineplus.gov)
  • Ivermectin is a remedy against scabies and certain parasites, and reportedly also has an effect on Covid-19 (6). (vitalraadet.dk)
  • The mites that cause scabies are parasites because they live by feeding on a person's blood. (msdmanuals.com)
Humans5
  • The FDA has not authorized or approved ivermectin for use in preventing or treating COVID-19 in humans or animals. (news-medical.net)
  • Animal ivermectin products are very different from those approved for humans. (news-medical.net)
  • Use of animal ivermectin for the prevention or treatment of COVID-19 in humans is dangerous. (news-medical.net)
  • Ivermectin, therefore, warrants further investigation for possible benefits in humans. (news-medical.net)
  • FDA is concerned about the health of consumers who may self-medicate by taking ivermectin products intended for animals, thinking they can be a substitute for ivermectin intended for humans. (medlineplus.gov)
Symptoms8
  • The most common signs and symptoms of scabies are intense itching (pruritus), especially at night, and a papular itchy rash. (cdc.gov)
  • For people who previously had scabies, symptoms appear much sooner, typically 1-4 days after exposure. (cdc.gov)
  • A diagnosis of scabies is made by a combination of physical exam, symptoms and skin scrapings examined under a microscope. (vetinfo.com)
  • Symptoms and signs of scabies include generalized intense itching. (emedicinehealth.com)
  • Scabies symptoms include extreme itching that is worse at night, pimple-like rash, and others. (emedicinehealth.com)
  • Dr. Jean-Jacques Rajter, a pulmonologist in Florida, was one of the first doctors to use ivermectin to treat patients with severe COVID-19 symptoms early on in the pandemic. (theepochtimes.com)
  • They have developed a protocol called I-MASK+ to prevent and treat early symptoms of COVID-19 after extensive research on ivermectin. (theepochtimes.com)
  • In older adults, scabies can cause intense itching but very mild skin symptoms, which makes it a challenge for doctors to diagnose. (msdmanuals.com)
Itchy skin1
  • Scabies is a skin disease characterized by severe itchy skin and a reddish rash that is contagious from person to person. (emedicinehealth.com)
Diagnosis1
  • Characteristic histopathology in the absence of actual mites also may suggest the diagnosis of scabies. (medscape.com)
Parasite2
  • In the last three to four months, emerging publications provide conclusive data on the profound efficacy of the anti-parasite, anti-viral drug, anti-inflammatory agent called ivermectin in all stages of the disease," Kory said. (theepochtimes.com)
  • Ivermectin is an important part of a parasite control program for certain species and should only be given to animals for approved uses or as prescribed by a veterinarian in compliance with the requirements for extra-label drug use. (medlineplus.gov)
Allergic3
Preventing COVID-191
  • During the COVID-19 pandemic, misinformation has been widely spread claiming that ivermectin is beneficial for treating and preventing COVID-19. (wikipedia.org)
Mites that cause1
  • Mites that cause scabies are usually destroyed by normal laundering (machine washing in hot water followed by drying in a hot dryer or ironing) or dry cleaning. (msdmanuals.com)
Parasitic disease2
  • However, only some 200 years later, was it generally accepted that scabies was a parasitic disease (Arlian 1989). (newworldencyclopedia.org)
  • Scabies is a neglected parasitic disease that is a major public health problem worldwide, and particularly in resource-poor regions. (who.int)
Treatments1
Topical2
Tablets1
  • Clinical trials assessing ivermectin tablets for the prevention or treatment of COVID-19 in people are ongoing. (news-medical.net)
Drugs1
  • Serious adverse effects have been reported for some drugs used to treat scabies. (cochrane.org)
Cuniculi1
  • cuniculi and divided into the following three groups: control, ivermectin-treated, and fluralaner-treated. (bvsalud.org)
Onchocerciasis1
  • Examples of this level of eradication are the use of chemotherapy with ivermectin to eliminate blindness resulting from onchocerciasis and of vitamin A to eliminate xerophthalmia. (cdc.gov)
Coronavirus2
  • They showed that Ivermectin reduced COVID-19 viral RNA present in cell culture by as much as 93 percent after 24 hours and by 99.8 percent after 48 hours, at around a 5,000-fold reduction in coronavirus RNA, hinting that the medicine can potentially eradicate the virus. (news-medical.net)
  • Though the mechanism of action by which Ivermectin works on the coronavirus is still unknown, the drug works on other viruses by stopping them from inhibiting down the host cells' ability to detect and fight them. (news-medical.net)
Severe1
  • People with scabies have severe itching, even though there are typically few mites on the body. (msdmanuals.com)
Norwegian1
  • 20 mites typically are found on a host with conventional scabies, a person with crusted scabies, formerly called Norwegian scabies, can harbor thousands of mites in just a small area of skin. (cdc.gov)
Infects1
  • When scabies infects many people at a nursing home, extended-care facility, and other institution, ivermectin may be prescribed to everyone who has a risk of catching scabies. (aad.org)
Usually spreads1
  • Scabies usually spreads from person to person through physical contact. (msdmanuals.com)
World Health Organ2
  • Multiple major health organizations, including the U.S. Food and Drug Administration, the U.S. Centers for Disease Control and Prevention, the European Medicines Agency, and the World Health Organization have stated that ivermectin is not authorized or approved to treat COVID-19. (wikipedia.org)
  • The World Health Organization (WHO) is planning a global program to control scabies. (emedicinehealth.com)
Typically2
  • Classic scabies typically has a distribution involving the axillae, elbow flexures, wrists and hands, and genital area. (medscape.com)
  • S. scabiei mites typically are adapted to their preferred host or hosts, and they may be unable to complete their life cycle in other, dissimilar hosts. (newworldencyclopedia.org)
Endemic1
  • Scabies is endemic in many resource-limited tropical settings. (acentds.org)
Treatment12
  • Ivermectin is also the primary treatment for Mansonella ozzardi and cutaneous larva migrans. (wikipedia.org)
  • The following medications for the treatment of scabies are available only by prescription. (cdc.gov)
  • Ivermectin appears to be an effective oral treatment. (cochrane.org)
  • Scabies can be passed between people and dogs although the dog scabies are not able to complete their life cycle on people so it will resolve without treatment. (vetinfo.com)
  • To get rid of scabies, treatment is essential. (aad.org)
  • The person diagnosed with scabies and everyone who has had close contact with that person need treatment. (aad.org)
  • Although FDA approved to treat scabies, this medication is generally only used when other scabies treatment fails. (aad.org)
  • 1. Someone you live with has scabies so you need to take the treatment. (discoverneem.com)
  • Scabies treatment requires prescription medications . (emedicinehealth.com)
  • Rajter says that ivermectin was soon adopted as part of the hospital's treatment protocol for COVID-19, and more than seven months later, "the success rate of the Ivermectin based protocol is now far superior to what it was in its early days. (theepochtimes.com)
  • The Indian health authorities have approved a treatment with Ivermectin, Doxycycline and zinc. (vitalraadet.dk)
  • The Importance of Scabies Coinfection in the Treatment Considerations for Impetigo. (medscape.com)
Intense2
  • Conventional scabies is characterized by intense itching, particularly at night, and by a papular or papulovesicular erythematous rash. (cdc.gov)
  • The hallmark of scabies is intense itching, which is usually worse at night. (msdmanuals.com)
Treats1
  • Medicine that treats scabies is only available with a doctor's prescription. (aad.org)
Paste1
  • 4. Baking soda (on alternate days) a paste made with a little water applied on skin) also painful but only painful where there are live scabies. (discoverneem.com)
Dogs2
Drug8
  • Ivermectin is an antiparasitic drug. (wikipedia.org)
  • The drug, Ivermectin , an antiparasitic medicine, is an inhibitor of the virus SARS-CoV-2 in-vitro and can effectively cause a reduction in virus at 48 hours in cell cultures. (news-medical.net)
  • Ivermectin is very widely used and seen as a safe drug. (news-medical.net)
  • Ivetab 6 mg contains the active substance Ivermectin, an FDA-approved antiparasitic drug used to treat several neglected tropical diseases. (reliablerxpharmacy.com)
  • They give your dog Ivermectin (the heartworm drug). (dogsnaturallymagazine.com)
  • But this drug can accelerate growth of scabies mites. (dogsnaturallymagazine.com)
  • A health worker shows a bottle of ivermectin, a medicine authorized by the National Institute for Food and Drug Surveillance to treat patients with mild, asymptomatic or suspicious COVID-19, as part of a study of the Center for Paediatric Infectious Diseases Studies, in Cali, Colombia, on July 21, 2020. (theepochtimes.com)
  • The Antiviral Research pre-publication paper, "The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro" documents how SARS-CoV-2 (the virus that causes COVID-19) responded to ivermectin when exposed in a petri dish. (medlineplus.gov)
Efficacy1
  • Cloudiness in the formulation may occur when Ivermectin Pour-On (generic) for Cattle is stored at temperatures below 32°F. Allowing to warm at room temperature will restore the normal appearance without affecting efficacy. (revivalanimal.com)
Inhibits1