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  • Drugs
  • Co-administration with Itraconazole can cause elevated plasma concentrations of these drugs and may increase or prolong both the pharmacologic effects and/or adverse reactions to these drugs. (drugs.com)
  • I read there is some interaction between these drugs, so, should I keep with my itraconazole treatment that I have already started two months ago? (thebody.com)
  • Other drugs used, such as amphotericin B, caspofungin (in combination therapy only), flucytosine (in combination therapy only), or itraconazole, are used to treat this fungal infection. (wikipedia.org)
  • dose
  • However, elderly patients are more likely to have temporary or permanent hearing loss or have kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving itraconazole. (mayoclinic.org)
  • The terminal half-life of Itraconazole generally ranges from 16 to 28 hours after single dose and increases to 34 to 42 hours with repeated dosing. (drugs.com)
  • Once treatment is stopped, Itraconazole plasma concentrations decrease to an almost undetectable concentration within 7 to 14 days, depending on the dose and duration of treatment. (drugs.com)
  • Went to the doctor for a fungal infection in my foot before I knew I was HIV positive, doctor prescribed itraconazole, 100mg pills twice a day for a week and stop for three weeks, then one week again taking the same dose and stop again for three weeks. (thebody.com)
  • For example, in a phase II study involving men with advanced prostate cancer, high-dose itraconazole (600 mg/day) was associated with significant PSA responses and a delay in tumor progression. (wikipedia.org)
  • Itraconazole consistently showed potent, specific, and dose-dependent inhibition of endothelial cell proliferation, migration, and tube formation in response to both VEGF- and basic fibroblast growth factor-mediated angiogenic stimulation. (aacrjournals.org)
  • Itraconazole is given with the steroids, as it is considered to have a "steroid sparing" effect, causing the steroids to be more effective, allowing a lower dose. (wikipedia.org)
  • prophylaxis
  • This is a prospective, open-label, multicenter, and observational study executed in 20 organizations nationwide with around 250 patients, in order to examine the correlation between a sufficient blood concentration of itraconazole and disappearance of a fever (defeverscence) when a itraconazole injection is administered for resolving unknown neutropenic fever of patients who are given itraconazole oral solution as a prophylaxis under general treatment conditions. (knowcancer.com)
  • inhibition
  • In vivo , using primary xenograft models of human NSCLC, oral itraconazole showed single-agent growth-inhibitory activity associated with induction of tumor hypoxia-inducible factor 1 alpha expression and marked inhibition of tumor vascularity. (aacrjournals.org)
  • vivo
  • Taken together, these data suggest that itraconazole has potent and selective inhibitory activity against multiple key aspects of tumor-associated angiogenesis in vitro and in vivo , and strongly support clinical translation of its use. (aacrjournals.org)
  • phase
  • Itraconazole also showed activity in a phase II trial in men with non-small cell lung cancer when it was combined with the chemotherapy agent, pemetrexed. (wikipedia.org)
  • present
  • (EN) The present invention provides a new crystalline form of itraconazole as well as the method of making same. (wipo.int)
  • In our aim to bring the best and complete information to our clients, we at Orbis Research present the 2017 Global Itraconazole Powder Market professional survey. (medgadget.com)