IgG1ReactivityPolyclonalImmunogenCloneSpecificityWestern blotAntigenTransmembraneTLRsPattern recognitiCells for antibody secretionProteinsMoleculesRecombinant ProteinPathogensInterleukinReacts with mouseSignal transductionTLR2RabbitLigandsAntigensMonoclonal antibodiesTested by flow cytometric analysisHumanMouseChemokineSecretionPURIFICATIONMicrobialTLR4ReconstituteFlow cytometryReconstitutionAffinity-chromatographyGeneCytokineBUFFERMyD88MembraneSodium azide
IgG12
- Staining of normal human peripheral blood cells with Anti-Human CD3 APC (Product # 17-0038-42) and 0.25 µg of Mouse IgG1 K Isotype Control eFluor® 450 (Product # 48-4714-82) (left) or Anti-Human CD8a eFluor® 450 (right). (thermofisher.com)
- Figure A. Alexa Fluor 647 conjugated Mouse anti Rat CD54 ( MCA773A647 ) and FITC conjugated Mouse IgG1 isotype control ( MCA1209F ). (bio-rad-antibodies.com)
Reactivity1
- In direct ELISAs and Western blots, approximately 30% cross-reactivity with recombinant mouse (rm) TLR6 is observed, 5% cross-reactivity with recombinant human (rh) TLR1 and rmTLR2 is observed, and less than 2% cross-reactivity with rhTLR3 and rhTLR4 is observed. (bio-techne.com)
Polyclonal5
- OR2T4 Polyclonal Antibody detects endogenous levels of protein. (antibodies-online.com)
- Western Blot analysis of RAT-MUSCLE cells using MyD88 Polyclonal Antibody. (assaygenie.com)
- IgG fraction from rabbit polyclonal antibody obtained by immunizing rabbits with a synthetic peptide (AENPEYLGLDVPV) corresponding to amino acids 1243-1255 of human c-erbB-2/HER-2/neu oncoprotein. (australbiologicals.com)
- This polyclonal antibody can be used in ELISA (1: 100 dilution), immunocytochemistry (1: 100 dilution) and it recognizes c-erbB-2 protein (185 kDa) in Western Blot of HeLa cell lysate (1: 500 dilution). (australbiologicals.com)
- Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. (avivasysbio.com)
Immunogen2
- The region of human TLR5 used as an immunogen includes the first 2 of 16 leucine-rich repeats and shares 72% amino acid identity with mouse and rat TLR5. (rndsystems.com)
- OR2T4 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. (antibodies-online.com)
Clone2
- Anti-hTLR6-IgG (clone C5C8) is a monoclonal antibody specific for human Toll-like receptor 6 (hTLR6, CD286). (invivogen.com)
- Phycoerythrin conjugated Mouse anti Rat CD161 antibody, clone 10/78 ( MCA1427PE ) used for the identification of NK cells in rat blood samples by flow cytometry. (bio-rad-antibodies.com)
Specificity2
- These Fc receptor-dependent antibody functions provide a direct link between the innate and adaptive immune systems by combining the potent antiviral activity of innate effector cells with the diversity and specificity of the adaptive humoral response. (frontiersin.org)
- Specificity This antibody recognizes human and mouse CXCR4 (40 kD). (qedbio.com)
Western blot2
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 19811-1-AP (TLR4 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. (ptglab.com)
- Western Blot: TLR2 Antibody [NB100-56720] - Analysis using the Azide Free version of NB100-56720. (novusbio.com)
Antigen8
- T independent antigen elicits antibody production by B lymphocytes without T lymphocyte involvement. (wikipedia.org)
- TI-1 antigen, which has an activity that can directly activate B cells and TI-2 antigen, which has highly repetitive structure and causes simultaneous cross-linking of specific B cell receptors (BCR) on B lymphocyte. (wikipedia.org)
- Antiviral activities of antibodies may either be dependent only on interactions between the antibody and cognate antigen, as in binding and neutralization of an infectious virion, or instead may require interactions between antibody-antigen immune complexes and immunoproteins or Fc receptor expressing immune effector cells. (frontiersin.org)
- The Fc receptor-dependent function of antibody-dependent cellular phagocytosis (ADCP) provides mechanisms for clearance of virus and virus-infected cells, as well as for stimulation of downstream adaptive immune responses by facilitating antigen presentation, or by stimulating the secretion of inflammatory mediators. (frontiersin.org)
- Fc receptor-dependent antibody functions are also involved in activation of downstream adaptive immune responses by facilitating antigen presentation or by stimulating the secretion of inflammatory mediators ( 12 , 13 ). (frontiersin.org)
- It has been proposed that long-lasting B cell ediated immunity is sustained by recurrent antigen exposure and within the absence of cognate antigen, inflammatory stimuli related with adaptive immune responses like cytokines, Toll-like receptor (TLR) agonists or T cell aid drive the activation of Bmem in an non-specific manner in vivo [10,11]. (cathepsin-s.com)
- Antibodies passively administered together with their specific antigen can enhance or suppress the specific antibody response. (avhandlingar.se)
- Whether this modulation causes up- or downregulation of the antibody response depends both on the antibody isotype and the antigen used. (avhandlingar.se)
Transmembrane8
- TLR5 is an ~100 kDa type I transmembrane glycoprotein of the Toll-like receptor family. (rndsystems.com)
- Cluster of differentiation 8 (CD8), a type I transmembrane glycoprotein of the immunoglobulin family of receptors, plays an integral role in signal transduction, and T cell differentiation and activation. (thermofisher.com)
- The Toll-like receptor (TLR) family in mammals comprises a set of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain, and in the IL-1 receptor motif in the cytoplasmic domain. (novusbio.com)
- TLR4, a member of the Toll-Like Receptor Family, has been renamed as CD284 and identified to be the transmembrane signal-transducing portion of the receptor for LPS. (bdbiosciences.com)
- IL-1 Rrp2, also known as IL-1 R6, is a transmembrane protein belonging to the IL-1 receptor family. (reliatech.de)
- In mammals, TLR identified as type I transmembrane signaling receptors with pattern recognition capabilities, have been implicated in the innate host defense to pathogens. (hycultbiotech.com)
- This family of type I transmembrane protein is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. (cytekbio.com)
- The Toll-like family of molecules are type I transmembrane proteins that serve as pattern recognition receptors for microbial pathogens. (bio-techne.com)
TLRs6
- Toll-like receptors (TLRs) play a key role in innate immune responses and inflammation. (diabetesjournals.org)
- Toll-like receptors (TLRs) play a critical role in early innate immunity to invading pathogens by sensing microorganisms. (invivogen.com)
- 13 A role for microbial signals via Toll-like receptors (TLRs) has been reported in mediating intestinal epithelial cell (IEC) and dendritic cell (DC) induction of the production of IgA through the induction of BAFF and APRIL. (nature.com)
- It expresses a range of cell surface molecules involved in adaptive and innate immunity, as well as crucial sentinel molecules, including toll-like receptors (TLRs), which are pivotal in early cellular defense against virus infection. (molvis.org)
- There are at least twelve mouse and ten human TLRs that activate the innate immune system following exposure to a variety of microbial species (1, 2). (bio-techne.com)
- TLRs contain a large number of leucine-rich repeats (LRRs) and a cytoplasmic tail with one Toll/IL-1 receptor (TIR) domain. (bio-techne.com)
Pattern recogniti2
- Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. (cytekbio.com)
- Accordingly, the innate immune system recognizes highly conserved components associated with infections and damaged cells using a limited number of pattern-recognition receptors (PRRs), which are differentially expressed across cell types. (avhandlingar.se)
Cells for antibody secretion2
- The pTfh cells represent around 15% of circulating Compact disc4 T cells in human beings [27] communicate CXCR5 and offer critical help B cells for antibody secretion within an IL-21-reliant way [26]. (healthdisparitiesks.org)
- The pTfh cells represent approximately 15% of circulating CD4 T cells in humans [27] communicate CXCR5 and provide critical help to B cells for antibody secretion in an IL-21-dependent manner [26]. (technuc.com)
Proteins2
- Comparative functional multiomics showed that blood proteins induce distinct receptor-mediated transcriptional programs in microglia and macrophages, such as redox, type I interferon and lymphocyte recruitment. (nature.com)
- We report a blood-induced microglia gene network and show that blood proteins elicit distinct receptor-mediated transcriptional changes and signaling programs in innate immune cells. (nature.com)
Molecules2
- whereas its counterpart, CD4, acts as a co-receptor for MHC-II molecules. (thermofisher.com)
- Moreover, treatment with imiquimod downregulated MHC class I molecules on tumor cells possibly resulting in a reduced binding affinity for inhibitory receptor NKG2A expressed on γδ T cells. (aacrjournals.org)
Recombinant Protein1
- This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of IL-1 R6 extracellular domain (also called IL-1 Rrp2). (reliatech.de)
Pathogens4
- These evolutionary conserved receptors recognize highly conserved structural motifs only expressed by microbial pathogens, called pathogen-associated microbial patterns (PAMPs). (invivogen.com)
- Fc receptor-dependent antibody functions are important components of the immune response that provide mechanisms for clearance of infected host cells, immune complexes, or opsonized pathogens. (frontiersin.org)
- Toll-like receptors (TLR) are highly conserved throughout evolution and have been implicated in the innate defense to many pathogens. (hycultbiotech.com)
- Protective T cell response against intracellular pathogens in the absence of Toll-like receptor signaling via myeloid differentiation factor 88. (mpg.de)
Interleukin6
- The most necessary are interleukin 2 (IL-2), interleukin 3 (IL-3) and interferon γ (IFN-γ). (wikipedia.org)
- High glucose increased TLR expression, myeloid differentiation factor 88, interleukin-1 receptor-associated kinase-1, and nuclear factor-κB (NF-κB) p65-dependent activation in THP-1 cells. (diabetesjournals.org)
- The Interleukin 1 receptor family comprises at least nine members. (rndsystems.com)
- Interleukin 1 receptor accessory protein-like 2 (IL1RAPL2), also known as TIGIRR1, is a member of the IL-1 RI-like family of the IL-1R/Toll-like receptor superfamily. (rndsystems.com)
- This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. (assaygenie.com)
- Era of cytotoxic T cells T cells in the peripheral bloodstream of a wholesome donor had been isolated utilizing a Skillet T Cell Isolation Package (Miltenyi Biotec) and cultured in RPMI 1640 (Lifestyle Technology) supplemented with 10% fetal leg serum, 100?IU/ml penicillin, 100?mg/ml streptomycin, 2?mM l-glutamine, 50?M -mercaptoethanol and 20?IU/ml interleukin 2 (PeproTech, Rocky Hill, USA). (memorial2014.com)
Reacts with mouse2
- Monoclonal antibody 6C2 reacts with mouse Toll-like receptor 2 (TLR2, CD282). (hycultbiotech.com)
- Description: The N418 monoclonal antibody reacts with mouse CD11c, the integrin alpha X. CD11c non-covalently associates with beta 2 integrin to form the CD11c/CD18 heterodimer. (thermofisher.com)
Signal transduction1
- TLR6 collaboration with TLR2 is essential for the recognition and signal transduction of diacylated LPs, such as MALP- 2 and FSL-1 [2, 3], as well as heat-killed mycoplasma, indicating that TLR6 and TLR2 play a central role in recognizing mycoplasma [2]. (invivogen.com)
TLR28
- This antibody can be used for the neutralization of hTLR6, it blocks cellular activation induced by agonists that are recognized by TLR6 and TLR2, such as FSL-1 . (invivogen.com)
- TLR6 co-operates with TLR2 to recognize diacylated lipoproteins (LPs) found in mycoplasma but is not required in the recognition of triacylated LPs found in bacteria [1, 2]. (invivogen.com)
- Detection of TLR2 in transfected cell lysate using this antibody. (novusbio.com)
- Immunohistochemistry-Paraffin: TLR2 Antibody [NB100-56720] - Analysis of mouse pancreas tissue using an isotype control (top) and this antibody (bottom) at 5 ug/ml. (novusbio.com)
- This antibody was developed against a mixture of synthetic peptides containing amino acids 180-196, 353-370, and 473-489 of human TLR2 (NP_003255). (novusbio.com)
- TLR2 has been identified as a receptor that is central to the innate immune response to lipoproteins of gram-negative bacteria, several whole gram-positive bacteria, as well as a receptor for peptidoglycan and lipoteichoic acid and other bacterial cell membrane products. (hycultbiotech.com)
- The currently accepted paradigm regards TLR2 as an essential receptor for many eubacterial cell wall components, including lipoproteins and peptidoglycan. (hycultbiotech.com)
- The antibody gives only a small inhibition of TLR2 (CD282) ligands in RAW cells. (hycultbiotech.com)
Rabbit1
- Immunohistochemical staining of perfusion-fixed frozen rat brain sections with Anti-LRRC33 (extracellular) Antibody (#ALR-043), (1:300), followed by goat anti-rabbit-AlexaFluor-488. (alomone.com)
Ligands1
- after incubation with interferon-gamma or toll-like receptors (TLR) ligands. (memorial2014.com)
Antigens10
- There are 2 distinct subgroups of TI antigens, different in mechanism of activating B lymphocytes. (wikipedia.org)
- For most protein antigens, the production of antibodies by B lymphocytes is dependent on stimulation of helper T cells. (wikipedia.org)
- The non-protein microbial antigens cannot stimulate classical T cell response by themselves, but they are able to elicit the production of antibodies, so that is why we call them T cell or thymus independent antigens. (wikipedia.org)
- T independent antigens are divided into 2 classes by the mechanism of activating B cells. (wikipedia.org)
- TI-1 antigens activate B-cells via Toll like receptors, which are expressed in humans on the surface of B lymphocytes after BCR stimulation. (wikipedia.org)
- In higher concentrations, TI-1 antigens bind to BCR and TLR of various clones of B lymphocytes, which leads to production of multiclonal antibodies. (wikipedia.org)
- TI-2 antigens can activate only mature B lymphocytes. (wikipedia.org)
- That may explain why children up to 5 years are not capable of producing effective antibodies against polysaccharide antigens, as the majority of their B cell population is immature. (wikipedia.org)
- The generation of receptors specific for antigens is a unique and complex process that generates 10 12 specific receptors for each cell type of the adaptive immune system, including T and B cells. (medscape.com)
- Various cell types can process and present these antigens to T cells, or antigens may be soluble and bound to B-cell receptors. (medscape.com)
Monoclonal antibodies2
- Methods Monoclonal antibodies recognising the fibrinogen-like globe (FBG) of tenascin-C were generated by phage display. (bmj.com)
- But when the concentration of TI-1 is lower, it can activate only B lymphocytes with specific binding of TI-1 on their BCR, and leads to production of monoclonal antibodies. (wikipedia.org)
Tested by flow cytometric analysis3
- Applications Tested: This RPA-T8 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. (thermofisher.com)
- Applications Tested: This UT41 antibody has been tested by flow cytometric analysis of mouse thioglycolate-elicited peritoneal exudate cells. (cytekbio.com)
- Applications Tested: This N418 antibody has been tested by flow cytometric analysis of mouse splenocytes. (thermofisher.com)
Human11
- Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 19811-1-AP (TLR4 Antibody) at dilution of 1:200 (under 10x lens). (ptglab.com)
- Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 19811-1-AP (TLR4 Antibody) at dilution of 1:200 (under 40x lens). (ptglab.com)
- Involvement of leucine residues at positions 107, 112, and 115 in a leucine-rich repeat motif of human Toll-like receptor 2 in the recognition of diacylated lipoproteins and lipopeptides and Staphylococcus aureus peptidoglycans. (invivogen.com)
- Description: The RPA-T8 monoclonal antibody reacts with the human CD8a molecule, an approximately 32-34 kDa cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). (thermofisher.com)
- Antibodies are a key component of the human adaptive immune system, and the elicitation of antibodies has been correlated with vaccine efficacy in many diseases ( 1 ). (frontiersin.org)
- The overexpression of the erbB-2 proto-oncogene is associated with an aggressive human adenocarcinomas, mainly breast and ovarian tumours. (australbiologicals.com)
- Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) for human immunodeficiency virus-1/HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. (qedbio.com)
- Antibodies to CXCR4 may block HIV-1 and HIV-2 infection of human target cells. (qedbio.com)
- Introduction Infectious diseases take a massive toll within the well being of both the elderly and the HIV-infected human population [1 2 The problem is particularly regarding in regards TMC353121 to to vaccine-preventable illnesses with up to at least one 1 0 situations greater threat of loss of life in old adults in comparison to vaccine-aged kids [3]. (healthdisparitiesks.org)
- Introduction Infectious diseases take a massive toll within the well being of both the elderly and the HIV-infected human population [1 2 The situation is particularly concerning with regard to vaccine-preventable diseases with up to 1 1 0 instances greater risk of death in older adults compared to vaccine-aged children [3]. (technuc.com)
- Human isotype‐dependent inhibitory antibody responses against Mycobacterium tuberculosis. (mpg.de)
Mouse7
- This Mouse TLR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-102 amino acids from the N-terminal region of mouse TLR5. (prosci-inc.com)
- The association of MD-2 with TLR4 is required for recognition of LPS and the anti-mitotic compound Taxol, which mimics the action of LPS on mouse cells. (bdbiosciences.com)
- MTS510 mAb detects TLR4-MD-2 on the surface of thioglycollate-elicited macrophages from all mouse strains tested (ie, BALB/c, C57BL/6, C3H/HeJ, C3H/HeN, and DBA/1), including the C3H/HeJ strain which expresses an LPS-resistant mutant TLR4. (bdbiosciences.com)
- Cutting edge: cell surface expression and lipopolysaccharide signaling via the toll-like receptor 4-MD-2 complex on mouse peritoneal macrophages. (bdbiosciences.com)
- Kawasaki K, Nogawa H, Nishijima M. Identification of mouse MD-2 residues important for forming the cell surface TLR4-MD-2 complex recognized by anti-TLR4-MD-2 antibodies, and for conferring LPS and taxol responsiveness on mouse TLR4 by alanine-scanning mutagenesis. (bdbiosciences.com)
- Description: The UT41 monoclonal antibody was generated against BaF3 cells overexpressing mouse TLR4. (cytekbio.com)
- The mouse monoclonal antibody 5E10 recognizes CD90/Thy-1, a GPI-anchored cell surface glycoprotein expressed predominantly on thymocytes, hematopoietic stem cells and neurons. (exbio.cz)
Chemokine5
- Biological Function Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation (PubMed:10452968, PubMed:28978524, PubMed:18799424, PubMed:24912431). (qedbio.com)
- Some G protein- coupled receptors in the chemokine receptor family, including CCR5, CXCR4, CCR3, CCR2b, and CCR8 in the chemokine receptor family, have been identified as HIV coreceptors. (qedbio.com)
- Functional annotation clustering of the microarray data showed that gene clusters involved in immune and antiviral responses ranked highly, involving genes such as chemokine (C-C motif) ligand 2 ( CCL2 ), chemokine (C-C motif) ligand 5 ( CCL5 ), chemokine (C-X-C motif) ligand 10 ( CXCL10 ), and toll like receptor 3 ( TLR3 ). (molvis.org)
- The non-proliferating ASC secrete higher affinity antigenspecific PDE5 Inhibitor Purity & Documentation antibodies (Abs) for protracted periods of time [1,4], are capable of homing to bone marrow (BM) by means of CXCR4/ CXCL12-mediated chemokine signaling or inflamed tissue and differ from Bmem in many respects. (cathepsin-s.com)
- Differential requirements for the chemokine receptor CCR7 in T cell activation during Listeria monocytogenes infection. (mpg.de)
Secretion2
- Macrophages are the main source of IL-10, and its secretion can be stimulated by endotoxin (via Toll-like receptor 4, NF-¿B dependent), tumor necrosis factor TNF-a (via TNF receptor p55, NF-¿B-dependent), catecholamines, and IL-1. (angioproteomie.com)
- Conclusions In ageing HIV-infected and uninfected ladies activated CD4 and pTfh cells may compromise influenza vaccine-induced antibody response for which a mechanism of TNFα-mediated impairment of pTfh-induced IL-21 secretion is definitely postulated. (healthdisparitiesks.org)
PURIFICATION1
- NA/LE refers to the culture and purification methods and buffer used to produce purified antibodies with no azide and low endotoxin: Aqueous buffered solution containing no preservative, 0.2µm sterile filtered. (bdbiosciences.com)
Microbial1
- TLR5, a Type I membrane protein belonging to the Toll-like receptor family, participates in the innate immune response to microbial agents. (prosci-inc.com)
TLR49
- Clones that neutralised FBG activation of toll-like receptor 4 (TLR4), without impacting pathogenic TLR4 activation, were epitope mapped by crystallography. (bmj.com)
- Activation of toll-like receptor 4 (TLR4) by tenascin-C, a matrix molecule persistently expressed at high levels in people with RA, drives chronic inflammation in models of rheumatoid arthritis (RA). (bmj.com)
- The MTS510 antibody reacts with the molecular complex of Toll-Like Receptor 4 and MD-2 (TLR4-MD-2) which is expressed on LPS responsive macrophages. (bdbiosciences.com)
- TLR4 associates on the cell surface with CD14 and MD-2, a 0.7 kDa molecule which is anchored to the membrane via its physical association with TLR4. (bdbiosciences.com)
- Expression of TLR4-MD-2 is down-regulated on peritoneal macrophages after exposure to LPS, correlating with the occurrence of LPS tolerance. (bdbiosciences.com)
- TLR4-MD-2 is not detected on splenocytes or thymocytes. (bdbiosciences.com)
- TLR4 physically associates with another molecule called MD-2, and together with CD14, this complex is responsible for LPS recognition and signaling. (cytekbio.com)
- The MTS510 monoclonal antibody co-immunoprecipitates MD-2 (~30 kDa) and TLR4 (~100 kDa), and preferentially reacts with TLR4 that is associated with MD-2. (cytekbio.com)
- In comparison, binding of the UT41 monoclonal antibody occurs with and without formation of the TLR4/MD-2 complex. (cytekbio.com)
Reconstitute1
- Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml. (reliatech.de)
Flow cytometry1
- The monoclonal antibody 6C2 can be used for flow cytometry and immuno precipitation. (hycultbiotech.com)
Reconstitution3
- 1 month, 2 to 8 °C under sterile conditions after reconstitution. (bio-techne.com)
- Storage before reconstitution The antibody ships as a lyophilized powder at room temperature. (alomone.com)
- Antibody concentration after reconstitution 0.8 mg/ml. (alomone.com)
Affinity-chromatography2
- Store undiluted at 4°C. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. (bdbiosciences.com)
- The antibody was purified by affinity chromatography. (angioproteomie.com)
Gene1
- Mutations of the signal transducer and activator of transcription 3 (STAT3) gene were shown to cause the AD HIES by 2 groups independently. (medscape.com)
Cytokine5
- Antibody efficacy in preventing RA synovial cell cytokine release, and in modulating collagen-induced arthritis in rats, was assessed. (bmj.com)
- Anti-FBG antibodies inhibited cytokine release by RA synovial cells and prevented disease progression and tissue destruction during collagen-induced arthritis. (bmj.com)
- these antibodies inhibit cytokine release by RA synovial cells and prevent disease progression and tissue destruction during collagen-induced arthritis. (bmj.com)
- IL-10 was first described as a cytokine that is produced by T helper 2 (Th2) cell clones. (angioproteomie.com)
- Plasma IL-21 the signature cytokine of T follicular helper cells (Tfh) and CD4 T cell IL-21R were upregulated with seroconversion (≥4 collapse increase in antibody titer). (healthdisparitiesks.org)
BUFFER3
- What buffer format is "Tnfrsf9 Antibody (OASA00035)" provided in? (avivasysbio.com)
- What buffer format is "LMTK2 Antibody - N-terminal region (OAAB16907)" provided in? (avivasysbio.com)
- When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Complete Staining Buffer (Product # SB-4401) to minimize any non-specific polymer interactions. (cytekbio.com)
MyD881
- MYD88: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (assaygenie.com)
Membrane2
- C-erbB-2 oncoprotein is a 185 kDa type I membrane tyrosine kinase receptor and belongs to the EGF receptor family. (australbiologicals.com)
- Activation of membrane receptors leads to NFKBI phosphorylation and ubiquitination, and its subsequent proteasomal degradation. (frontiersin.org)
Sodium azide1
- 0.5 ml (100 µg/ml) 0.2 µm filtered antibody solution in PBS, containing 0.1% bovine serum albumin and 0.02% sodium azide. (hycultbiotech.com)