AcuteOcclusionCause of ischemic strokeHemorrhagic strokeArteryAortic aneurysmCervicalAtherosclerosisVesselTransient ischemic attacksIntracranialVertebralOutcomeEtiologyThrombectomy in PatientsPathophysiologyPrevent ischemicSymptomsStrokesExtracranialSyndromesHemorrhageAtrial fibrillationCerebralPatients with spontaneousMyocardial infarctionMETHODSArterial dissectionsIschemiaCirculationEndovascularGeneticsStentHemodynamicAnticoagulationClinicalCervicocephalicPosteriorIncidenceMorbidityMechanicalClassification SystemAneurysms
Acute12
- Our stroke interventions include treatment of acute ischemic stroke with clot retrieval devices . (hopkinsmedicine.org)
- Classification of subtype of acute ischemic stroke. (nature.com)
- Previous classification systems of acute ischemic stroke (Causative Classification System, CCS, of acute ischemic stroke, Trial of Org 10172 in Acute Stroke Treatment, TOAST) established the diagnosis of large artery disease (LAD) based on the presence or absence of carotid stenosis. (karger.com)
- Mechanical thrombectomy, in addition to intravenous thrombolysis, has become standard in acute ischemic stroke treatment in patients with large-vessel occlusion in the anterior circulation. (ajnr.org)
- The clinical outcome of patients undergoing mechanical thrombectomy for acute ischemic stroke with mild stroke due to large-vessel occlusion appears to be predominately favorable, even in a prolonged time window. (ajnr.org)
- In several randomized multicenter stroke trials, mechanical thrombectomy has proved to be an effective treatment for large intracranial vessel occlusion in patients with acute ischemic stroke in the anterior circulation. (ajnr.org)
- Acute aortic dissection (AAD) is one of the "big four" deadly threats in emergency department (ED) patients presenting with chest pain-the other three being acute coronary syndrome , pulmonary embolus , and pericarditis /tamponade. (medscape.com)
- Acute ischemic stroke in patients younger than the age of 50 years is a rare occurrence that results in high mortality and substantial loss of functional years of life. (springermedizin.at)
- Internal carotid artery dissection (CAD) presents a rare, but serious condition that needs to be fully evaluated and carefully treated, as it may lead to an acute ischemic stroke in all, but mostly in younger patients. (springermedizin.at)
- In this case report we present a case of a young patient with carotid artery type of ESy, resulting in a severe acute ischemic stroke. (springermedizin.at)
- In this work we prospectively studied the frequency and characteristics of de novo headache related to thrombectomy in a series of consecutive patients attending our hospital with acute ischemic stroke. (biomedcentral.com)
- Among the types of stroke, acute ischemic stroke (AIS) caused by large vessel occlusion (LVO) can cause severe disabilities and life threatening conditions [ 9 ]. (the-jcen.org)
Occlusion1
- Cerebral angiogram of a left internal carotid dissection showing gradual vessel tapering to occlusion. (medscape.com)
Cause of ischemic stroke2
- Carotid artery dissection is a significant cause of ischemic stroke in all age groups, but it occurs most frequently in the fifth decade of life and accounts for a much larger percentage of strokes in young patients. (medscape.com)
- Conclusions -CD is an important cause of ischemic stroke in young and middle-aged patients. (noigroup.com)
Hemorrhagic stroke1
- Viz.ai uses artificial intelligence to find suspected aortic dissection, pulmonary embolism, ischemic stroke, and hemorrhagic stroke. (acc.org)
Artery29
- Carotid artery dissection begins as a tear in one of the carotid arteries of the neck, which allows blood under arterial pressure to enter the wall of the artery and split its layers. (medscape.com)
- [ 1 ] Dissection of the internal carotid artery can occur intracranially or extracranially, with the latter being more frequent. (medscape.com)
- Internal carotid artery dissection can be caused by major or minor trauma, or it can be spontaneous, in which case, genetic, familial, or heritable disorders are likely etiologies. (medscape.com)
- Once diagnosed and treated, patients with carotid artery dissection require regular follow-up and imaging studies of both carotid arteries. (medscape.com)
- It is widely accepted that carotid artery dissection is a multifactorial disease. (medscape.com)
- Carotid artery dissection begins as a tear in the tunica intima or directly within the tunica media (possibly originating from the vasa vasorum). (medscape.com)
- [ 1 , 2 ] The dilatation resulting from an internal carotid artery dissection may be termed a true rather than a false aneurysm because the wall is composed of blood vessel elements. (medscape.com)
- Thrombolysis in cervical artery dissection--data from the Cervical Artery Dissection and Ischaemic Stroke Patients (CADISP) database. (hal.science)
- OBJECTIVE: To examine whether thrombolysis for stroke attributable to cervical artery dissection (CeAD(Stroke) ) affects outcome and major haemorrhage rates. (hal.science)
- Differential features of carotid and vertebral artery dissections: The CADISP Study. (medscape.com)
- Endovascular treatment of vertebral artery dissections and pseudoaneurysms. (medscape.com)
- Antiplatelet treatment compared with anticoagulation treatment for cervical artery dissection (CADISS): a randomised trial. (medscape.com)
- Kim YK, Schulman S. Cervical artery dissection: pathology, epidemiology and management. (medscape.com)
- Differences in demographic characteristics and risk factors in patients with spontaneous vertebral artery dissections with and without ischemic events. (medscape.com)
- The genetics of cervical artery dissection: a systematic review. (medscape.com)
- Georgiadis D, Arnold M, von Buedingen HC, Valko P, Sarikaya H, Rousson V. Aspirin vs anticoagulation in carotid artery dissection: a study of 298 patients. (medscape.com)
- Clinical and radiographic natural history of cervical artery dissections. (medscape.com)
- Axial T1-weighted MRI demonstrating a crescent sign (arrow) in a patient with a left internal carotid artery dissection. (medscape.com)
- An arterial dissection is a tear in an artery that supplies blood to the brain. (healthline.com)
- 2016 . Cervical artery dissections: a review . (ajtmh.org)
- COVID-19 and cervical artery dissection-causative association? (ajtmh.org)
- Unilateral common carotid artery dissection in a patient with recent COVID-19: an association or a coincidence? (ajtmh.org)
- In order to reduce ischemic time during surgery, it is especially important to reduce the time required for debridement, exploration, and bone fixation, which are the steps before artery anastomosis. (biomedcentral.com)
- Low- to moderate-risk patients still require definitive diagnosis of coronary artery disease as well as identifying not infrequent, unique ischemic syndromes such as myocardial infarction with nonobstructive coronary arteries, spontaneous coronary artery dissection, myocarditis, and takotsubo syndrome. (acc.org)
- Introduction Endovascular intervention for cervical carotid artery dissection (CAD) and vertebral artery dissection (VAD) may be indicated in specific circumstances. (bmj.com)
- Methods- Copy number variation was identified in high-density single-nucleotide polymorphism microarray data of IS patients from the CADISP (Cervical Artery Dissection and Ischemic Stroke Patients) and SiGN (Stroke Genetics Network)/GISCOME (Genetics of Ischaemic Stroke Functional Outcome) networks. (lu.se)
- In one community-based study, the average annual incidence of spontaneous cervical internal carotid artery dissections was 2.6 cases per 100,000. (medscape.com)
- While some studies have reported that males and females are affected equally in extracranial carotid dissections, the Cervical Artery Dissection and Ischemic Stroke Patients (CADISP) group reported that cervical artery dissection was more common in men and men were older at onset. (medscape.com)
- Extracranial vertebral artery dissections and multiple vessel dissections are more common in women than in men. (medscape.com)
Aortic aneurysm1
- Several molecular pathways and the activation of matrix metalloproteinases associated with the pathogenesis of SS participate in the initiation and progression of aortic aneurysm (AA) and aortic dissection (AD). (bmj.com)
Cervical3
- The author of the post on SBM questions the Stroke paper's treatment of a key study, Cassidy et al (2008) published in Spine, that is often used to support the notion that the correlation between cervical manipulation and cervical arterial dissection is NOT causal - suggesting that cervical manipulation is safe. (noigroup.com)
- Objective To review our institutional experience with endovascular treatment of cervical dissections over the past 20 years to examine indications for treatment, interventional methods, and outcomes. (bmj.com)
- Dissection of the cervical and intracranial vessels is an uncommon but increasingly recognized condition. (medscape.com)
Atherosclerosis1
- Recommendations are also provided for the prevention of recurrent stroke in a variety of specific circumstances, including aortic arch atherosclerosis, arterial dissection, patent foramen ovale, hyperhomocysteinemia, hypercoagulable states, antiphospholipid antibody syndrome, sickle cell disease, cerebral venous sinus thrombosis, and pregnancy. (nih.gov)
Vessel6
- Dissection occurs when blood extrudes into the connective tissue framework of a vessel wall, causing separation of the natural vessel layers. (medscape.com)
- The hallmark of dissection is hemorrhage within the vessel wall. (medscape.com)
- In intracranial carotid and vertebral dissections, subintimal tears occur more commonly, leading to formation of intramural hematomas that protrude inward and narrow the vessel lumen. (medscape.com)
- Most ischemic symptoms (85-95%) are caused by emboli from the site of the dissection, while the remainder are due to vessel narrowing with hemodynamic insufficiency (5-15%) or a combination of both. (medscape.com)
- Morbidity and mortality of cervicocephalic dissections vary according to the vessel and location of the dissection. (medscape.com)
- Some of the best known are arterial wall dissection or bleeding due to vessel perforation. (biomedcentral.com)
Transient ischemic attacks2
- Patients may present with asymmetric pulses or unequal blood pressure measurements between limbs (eg, between limbs on opposite sides or between the arm and leg on the same side), limb claudication, symptoms of decreased cerebral perfusion (eg, transient visual disturbances, transient ischemic attacks, strokes), and hypertension or its complications. (msdmanuals.com)
- Involvement of the carotid and vertebral arteries results in reduced cerebral blood flow manifested by dizziness, syncope, orthostatic hypotension, headaches, transient visual disturbances, transient ischemic attacks, or strokes. (msdmanuals.com)
Intracranial6
- BACKGROUND: The prognosis of ischemic anterior circulation intracranial dissection (AC-ICD) is poor and its optimal management is still controversial. (elsevierpure.com)
- Yamaura A. Nontraumatic Intracranial Arterial Dissection: Natural History, Diagnosis, and Treatment. (medscape.com)
- However, there are concerns regarding the adverse effects associated with statin use in ischemic stroke such as intracranial hemorrhage. (neurologyindia.com)
- In contrast, mortality rates for intracranial carotid and basilar dissections approach 70% or higher. (medscape.com)
- Intracranial dissections are more common in younger males than in females. (medscape.com)
- Intracranial carotid dissection tends to occur particularly in adolescents and adults younger than 30 years. (medscape.com)
Vertebral1
- In extracranial carotid and vertebral dissections, hemorrhage into the medial-adventitial layers occurs most commonly. (medscape.com)
Outcome3
- Furthermore, good adherence is associated with a better clinical outcome, and statin withdrawal is associated with a poor functional outcome in patients with ischemic stroke. (neurologyindia.com)
- Background and Purpose- We sought to explore the effect of genetic imbalance on functional outcome after ischemic stroke (IS). (lu.se)
- Background/Aim: Signs of hypoxic ischaemic encephalopathy (HIE) on head computed tomography (CT) predicts poor neurological outcome after cardiac arrest. (lu.se)
Etiology1
- The cohorts were well matched for age, sex, dissection etiology, and admission and follow-up modified Rankin Scale (mRS) scores. (bmj.com)
Thrombectomy in Patients1
- Our aim was to study the frequency and characteristics of headache specifically related to thrombectomy in patients with ischemic stroke. (biomedcentral.com)
Pathophysiology2
- The pathophysiology of ischemic stroke may depend on the underlying cause of ischemia . (wikidoc.org)
- In addition, white blood cells (WBC) contributed to the pathophysiology of ischemic changes in the brain, and activated leukocytes are released in damaged brain tissues with pro-inflammatory chemokines [ 14 , 18 ]. (the-jcen.org)
Prevent ischemic2
- How to best prevent ischemic stroke in patients who present with purely local signs such as headache, painful Horner Syndrome or neck pain? (nih.gov)
- Appropriate treatment of hypertensive emergency lowers blood pressure to prevent continued end-organ damage but does so slowly and gradually to prevent ischemic damage. (unboundmedicine.com)
Symptoms4
- Ischemic stroke may be classified according to the duration of onset of symptoms and causative agent. (wikidoc.org)
- The purpose of this analysis was to assess clinical and interventional data in patients treated with mechanical thrombectomy in case of ischemic stroke with mild-to-moderate symptoms. (ajnr.org)
- One lethal procedural complication occurred, and transient ischemic symptoms appeared in 2 patients. (ajnr.org)
- Health care providers should remind patients of the potential for stroke and arterial dissection at each treatment visit and advise them to seek immediate medical attention if they experience any of the symptoms reported in previous cases. (mdedge.com)
Strokes1
- Hospital-based series suggest that cervicocephalic dissections are responsible for 1-2.5% of ischemic strokes in the general population and for 5-20% of strokes in individuals younger than 45 years. (medscape.com)
Extracranial3
- very few patients of AD-PCS had dissection solely in extracranial arteries. (tmu.edu.tw)
- Methods Retrospective review of a prospectively maintained database to identify patients with extracranial dissection who underwent endovascular intervention between January 1996 and January 2016. (bmj.com)
- In extracranial carotid dissection, 70% of cases occur in persons aged 35-50 years. (medscape.com)
Syndromes1
- International frequency of dissection syndromes is similar to that in the United States. (medscape.com)
Hemorrhage3
- B) Subadventitial dissection represents hemorrhage between media and adventitia. (medscape.com)
- No patients had subarachnoid hemorrhage or ischemic symptom recurrence during the clinical follow-up (mean, 27 months). (elsevierpure.com)
- The management of cervicocephalic arterial dissections raises many unsolved issues such as: how to best acutely treat patients who present with ischemic stroke or occasionally with sub-arachnoid hemorrhage? (nih.gov)
Atrial fibrillation2
- Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke. (nature.com)
- A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke. (nature.com)
Cerebral1
- Hemodynamic changes in ischemic stroke results from cerebral auto regulation dysfunction as brain tissue is highly sensitive to mild changes in oxygen levels. (wikidoc.org)
Patients with spontaneous1
- Six of 67 (9.0%) patients with spontaneous dissection reported recent chiropractic manipulation. (bmj.com)
Myocardial infarction1
- This was based on the results of the ACCOAST (A Comparison of Prasugrel at PCI or Time of Diagnosis of Non-ST Elevation Myocardial Infarction) trial, which found no difference in ischemic outcomes with an increased risk of bleeding with prasugrel pretreatment. (acc.org)
METHODS1
- METHODS: Eight patients (mean age, 36 years) underwent self-expanding stenting for ischemic AC-ICD. (elsevierpure.com)
Arterial dissections1
- How long and how should patients be treated after cervicocephalic arterial dissections? (nih.gov)
Ischemia1
- Posterior ischemic optic neuropathy (PION) is a medical condition characterized by damage to the retrobulbar portion of the optic nerve due to inadequate blood flow (ischemia) to the optic nerve. (wikipedia.org)
Circulation2
- Background: Posterior circulation ischemic stroke (PCS) caused by arterial dissection (AD-PCS) was rarely discussed. (tmu.edu.tw)
- Inclusion criteria were anterior circulation ischemic stroke treated with mechanical thrombectomy at our institution between September 2010 and October 2015 with an NIHSS score of ≤8. (ajnr.org)
Endovascular1
- Almost one-third of patients with ischemic stroke who undergo endovascular thrombectomy experience headache in the first 24 hours, occurring more frequently in patients who had a previous history of headaches regardless of the procedure complexity. (biomedcentral.com)
Genetics2
- Dichgans, M. Genetics of ischaemic stroke. (nature.com)
- Markus, H.S. Genetics studies in ischaemic stroke. (nature.com)
Stent1
- OBJECTIVE: To evaluate the safety and efficacy of a self-expanding stent for ischemic AC-ICD. (elsevierpure.com)
Hemodynamic1
- Urgent invasive treatment is indicated only for significant ischemic and/or hemodynamic instability. (acc.org)
Anticoagulation1
- Antiplatelets vs anticoagulation for dissection: CADISS nonrandomized arm and meta-analysis. (medscape.com)
Clinical2
- Imaging findings of ischemic AC-ICD, the reason for stenting, and the clinical and angiographic outcomes were retrospectively evaluated. (elsevierpure.com)
- Meanwhile, cervicocephalic arterial dissection remains a situation when a bedside clinician should use, on a case-by-case basis, best clinical judgment and adopt a stepped care approach in the minority of patients who deteriorate despite initial treatment. (nih.gov)
Cervicocephalic2
- The consensus is that, given the well-established initial thromboembolic risk, an urgent antithrombotic treatment is required in patients with a recent nonhemorrhagic cervicocephalic arterial dissection, but the type of antithrombotic treatment - anticoagulants or aspirin - as well as the indication for a local arterial treatment such as angioplasty/stenting remain debated. (nih.gov)
- Cervicocephalic dissections may occur spontaneously or secondary to major or minor trauma. (medscape.com)
Posterior1
- Weeks after ischemic insult, nerve atrophy originating from the damaged posterior optic nerve progresses to involve the anterior optic nerve head. (wikipedia.org)
Incidence1
- Healing usually takes 3-6 months, and the incidence of contralateral dissection is higher in these patients than in the general population. (medscape.com)
Morbidity1
- Stroke is a major cause of mortality and morbidity, and ischemic stroke accounts for about 80% of all stroke [ 12 , 32 ]. (the-jcen.org)
Mechanical1
- Our aim was to prospectively study de novo headaches in a minimum of 100 patients (with headache in a minimum of 30) in whom a mechanical thrombectomy due to ischemic stroke was performed. (biomedcentral.com)
Classification System2
- Our objective was to update definitions of ischemic stroke subtypes to improve the detection of LAD and to assess the validity and reliability of a new classification system: SPARKLE (Subtypes of Ischaemic Stroke Classification System). (karger.com)
- The major classification system of ischemic stroke include toast classification system, causative classification of stroke system (CCS),and sparkle classification of ischemic stroke. (wikidoc.org)
Aneurysms1
- In this series, most peripheral PICA aneurysms were secondary to arterial dissection. (ajnr.org)