• Burkitt's lymphoma. (medscape.com)
  • Burkitt's lymphoma in a patient with adenosine deaminase deficiency-severe combined immunodeficiency treated with polyethylene glycol-adenosine deaminase. (medscape.com)
  • Burkitt's lymphoma: clinicopathologic features and differential diagnosis. (medscape.com)
  • Virus particles in cultured lymphoblasts from Burkitt's lymphoma. (medscape.com)
  • The award recognises people with the integrity, compassion and dedication matching that of Denis Burkitt, a Trinity graduate who is known for his discovery of Burkitt's lymphoma. (tcd.ie)
  • We are honoured that Professor Dalla-Favera, with his outstanding scientific record based directly on Denis Burkitt's work, is the recipient of the Burkitt Medal 2015. (tcd.ie)
  • This work established the basis for the seminal work on the involvement of c-MYC in chromosomal translocations in Burkitt's lymphoma. (tcd.ie)
  • Its involvement in cancers such as medulloblastoma, neuroblastoma, and Burkitt's lymphoma is examined, as are the prospects for anti-MYC therapies in cancer treatment. (cshlpress.com)
  • Neurological manifestations of Burkitt's lymphoma in Ghana. (edu.gh)
  • Over a period of 2 1/4 years, 75 patients with histologically confirmed Burkitt's lymphoma were evaluated at the Korle Bu Teaching Hospital in Accra. (edu.gh)
  • Ten of the lymphomas were undifferentiated, 5 of Burkitt's type and 5 non-Burkitt's type. (nih.gov)
  • Burkitt's lymphoma: clinic progression and prognosis. (bvsalud.org)
  • Burkitt's lymphoma is one of the fastest growing malignancies in the pediatric population. (bvsalud.org)
  • The African, or endemic, variant usually involves the maxilla and other facial bones, while head and neck manifestations in sporadic Burkitt's lymphoma are rare. (bvsalud.org)
  • Two cases of oral manifestations of Burkitt's lymphoma are described on the right jaw in young patients, which had different clinical evolution and prognosis. (bvsalud.org)
  • Burkitt's lymphoma was first characterized by Denis Burkitt in 1958 while he was a surgeon for the Colonial Medical Service in Uganda. (bvsalud.org)
  • The clinical presentation of Burkitt's lymphoma is characte- rized by rapid progression of symptoms with frequent multifocal extranodal involvement. (bvsalud.org)
  • This paper describes two cases of oral Burkitt's lymphoma in two young boys, which had different clinical evolution and prognosis. (bvsalud.org)
  • The histopathological picture showed small round cells with scarce cytoplasm and multiple small nuclei interspersed by macrophages in the process of phagocytosis, consistent with diagnosis of BurkittĀ“s lymphoma ( Fig. 3a ).Immunohistochemical examination showed diffusely positive for CD 20 and CD10, weakly positive for CD 3, negative for CD 5 and positive in more than 90% for Ki-67, confirming the diagnosis of Burkitt's lymphoma ( Fig. 3b ). (bvsalud.org)
  • there was no significant difference in the incidence of Burkitt's lymphoma (BL) by sex ( P=0.423). (bvsalud.org)
  • An ovarian involvement by non-Hodgkin lymphoma (NHL) may include one of the four subtypes of lymphoma: diffuse large B-cell lymphoma, Burkitt's lymphoma (BL), lymphoblastic lymphoma or anaplastic large cell lymphoma. (biomedcentral.com)
  • Burkitt's lymphoma is a rare entity with a specific poorly differentiated pattern. (biomedcentral.com)
  • Here we report a case of a primary ovarian Burkitt's lymphoma with bilateral involvement in a 57 year old patient. (biomedcentral.com)
  • The management of central nervous system (CNS) involvement is relatively clear in acute lymphoblastic leukemia (ALL) and Burkitt's leukemia/lymphoma (BL). (hacettepe.edu.tr)
  • EBV was the first virus to be associated with human malignancy, which was discovered from a Burkitt's lymphoma cell line in 1964 ( 1 ). (spandidos-publications.com)
  • I. Determine the response rate (complete and partial) in patients with relapsed or refractory Burkitt's, mantle cell or diffuse large cell non-Hodgkin's lymphoma treated with FR901228 (depsipeptide). (knowcancer.com)
  • Among peripheral B-cell lymphomas, the major difficulty is to differentiate BL from diffuse large B-cell lymphoma (DLBCL) , lymphoblastic lymphoma , and blastic mantle cell lymphoma (MCL) . (medscape.com)
  • In the 2008 World Health Organization (WHO) classification system, these are referred to as "B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma. (medscape.com)
  • In search for subgroups of diffuse large B-cell lymphoma (DLBCL) with different histogenetic origin and prognosis, as has been described by gene expression profiling, we examined tumor specimens from 125 patients with DLBCL, uniformly treated by either cyclophosphamideAdriamycin-vincristine-prednisone or methotrexate, doxorubicin, cyclophosphamide, vincristine, prednisone, and bleomycin in a multicenter trial set by the Nordic Lymphoma Group 1989-1994. (aacrjournals.org)
  • 3 - 5 This report by the Spanish Lymphoma Group (GELTAMO) aims to provide useful guidelines and recommendations for the prevention, diagnosis, and treatment of central nervous system diffuse large B-cell lymphoma patients with, or at risk of, leptomeningeal and/or brain parenchyma lymphoma relapse. (haematologica.org)
  • Several factors hinder the identification of risk factors for central nervous system (CNS) involvement in diffuse large B-cell lymphoma (DLBCL), including the retrospective nature of most studies, the relatively low frequency of CNS relapse in DLBCL, and the heterogeneity of CNS prophylaxis methods used in these studies. (haematologica.org)
  • The research interests of Joo Song, M.D., are focused on the genomics, prognostication, and classification of aggressive lymphomas such as Hodgkin lymphoma and diffuse large B cell lymphoma. (cityofhope.org)
  • HGBL, not otherwise specified (NOS) is a heterogeneous, aggressive, mature B-cell lymphoma that does not meet criteria for BL, DHL, or diffuse large B-cell lymphoma NOS. (cancernetwork.com)
  • Using Rappaport's classification, diffuse histiocytic lymphoma was the most frequent histologic type and constituted 60% of the cases. (nih.gov)
  • Immunohistochemistry staining tested positive for CD20 ( Figure 4 ), leading to a diagnosis of right atrial diffuse large B cell lymphoma, non-germinal center (activated) type. (frontiersin.org)
  • CT scan of mediastinum shows diffuse lymphatic swelling (arrow) over right supraclavicular (A) , pre-vascular (B-D) and aortopulmonary (C) station with inhomogeneous enhancing after contrast media, suggestive for lymphoma. (biomedcentral.com)
  • Malignant blast cells (i.e. diffuse large B-cell lymphoma) are fast-growing and result in aggressive disease, whereas malignant mature lymphocytes (i.e. follicular lymphoma) behave indolently. (oncolink.org)
  • The purpose of the study is to find out if an investigational drug called PRGN-3007 UltraCAR-T cells (PRGN-3007 T cells) can help people with ROR1-positive hematologic chronic lymphocytic leukemia (CLL), mantle cell lymphoma (MCL), acute lymphoblastic leukemia (ALL), diffuse large B-cell lymphoma (DLBCL) and solid tumor triple negative breast cancer (TNBC) malignancies. (moffitt.org)
  • Malignant lymphoma in African children. (medscape.com)
  • Malignant causes included primary or secondary cardiac tumors, lung cancer, mediastinal tumors, or lymphoma, which may obstruct or compress the superior vena cava. (frontiersin.org)
  • Non-Hodgkin Lymphomas Non-Hodgkin lymphomas are a heterogeneous group of disorders involving malignant monoclonal proliferation of lymphoid cells in lymphoreticular sites, including lymph nodes, bone marrow, the. (msdmanuals.com)
  • Burkitt lymphoma is the most rapidly growing human tumor, and pathology reveals a high mitotic rate, a monoclonal proliferation of B cells, and a "starry-sky" pattern of benign macrophages that have engulfed apoptotic malignant lymphocytes. (msdmanuals.com)
  • The diagnosis of malignant lymphoma was established after bilateral adnexectomy and histological study of the excised tissue. (biomedcentral.com)
  • Malignant lymphomas, which may regress following withdrawal of methotrexate, may occur in patients receiving low-dose methotrexate and, thus, may not require cytotoxic treatment. (nih.gov)
  • Malignant lymphoma composed of large B lymphoid cells whose nuclear size can exceed normal macrophage nuclei, or more than twice the size of a normal lymphocyte. (lookformedical.com)
  • Most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation. (lookformedical.com)
  • The area of research for our group is malignant lymphomas - all possible aspects, aiming for the improvement of the quality of life and survival of these patients. (lu.se)
  • It is named after Denis Parsons Burkitt, the Irish surgeon who first described the disease in 1958 while working in equatorial Africa. (wikipedia.org)
  • Denis Parsons Burkitt, a surgeon and research scientist who is a household name in the medical profession received his BA in 1933 and graduated from Trinity as a physician in 1935. (tcd.ie)
  • The discovery of the BCL2 gene and its involvement in follicular lymphoma and in other malignancies. (grantome.com)
  • The t(14;18) translocation (characteristic for follicular lymphoma but also common in other types) results in activation of the BCL-2 gene and suppression of apoptosis. (oncolink.org)
  • Important types include follicular lymphoma and small lymphocytic lymphoma . (oncolink.org)
  • The diagnosis of CBCL is established by analysis of skin biopsy specimen, using histomorphology and cytomorphology, immunohistochemistry and phenotypic features, and genotyping and cytogenetic studies (see Workup of Cutaneous B-Cell Lymphoma). (medscape.com)
  • This confirmed the diagnosis of primary cardiac lymphoma (PCL). (frontiersin.org)
  • however, it may involve the brain, spinal cord, leptomeninges, or eyes without evidence of systemic involvement at the time of diagnosis. (thieme-connect.com)
  • Central nervous system (CNS) involvement is often present at diagnosis or with relapsing lymphoma. (msdmanuals.com)
  • All analyses were done by modified intention-to-treat, excluding randomly assigned patients who were subsequently found to have CNS involvement or diagnosis other than Burkitt lymphoma at study entry. (bvsalud.org)
  • Five patients were excluded after random assignment (three in the R-CODOX-M/R-IVAC group [one diagnosis other than Burkitt lymphoma at study entry according to local pathology and two CNS involvement] and two in the DA-EPOCH-R group [one diagnosis other than Burkitt lymphoma at study entry according to local pathology and one CNS involvement]. (bvsalud.org)
  • Case 3, a patient with human immunodeficiency virus infection, had the diagnosis of B-LBL made on a retroperitoneal lymph node biopsy and had no peripheral blood or bone marrow involvement. (ipathology.cn)
  • Fine-needle aspirate is sufficient for lymphoma diagnosis but rarely adequate for subtyping, thus excisional or incisional biopsy is considered mandatory[5]. (oncolink.org)
  • Two different studies explored gene-expression profiling by microarray technology as a tool to accurately diagnose Burkitt lymphoma (BL) and differentiate it from DLBCL due to the significant difference in prognosis and treatment approaches for these diseases. (medscape.com)
  • [ 49 , 50 ] Moreover, patients with a Burkitt lymphoma (BL) signature who were treated with CHOP-like (cyclophosphamide, hydroxydaunorubicin hydrochloride [doxorubicin hydrochloride], vincristine and prednisone) regimens had a worse prognosis than those patients who were treated with more intense chemotherapy regimens. (medscape.com)
  • Burkitt lymphoma is uncommon in adults, in whom it has a worse prognosis. (wikipedia.org)
  • Non-Hodgkin lymphoma (NHL) represents a heterogeneous group of malignancies of different biology and prognosis. (medscape.com)
  • Likewise, with primary cutaneous lymphomas associated with a poorer prognosis, treatment is different for isolated or grouped lesions than for multiple lesions (see Treatment and Management). (medscape.com)
  • The belief that T-cell lymphomas have a worse prognosis than B-cell lymphomas remains controversial. (oncolink.org)
  • 2. Clinical epidemiology - using data from the Swedish Lymphoma Registry to provide clinically useful real world data on treatment and prognosis, in many cases in collaboration with Nordic colleagues. (lu.se)
  • Burkitt lymphoma can be divided into three main clinical variants: the endemic, the sporadic, and the immunodeficiency-associated variants. (wikipedia.org)
  • The sporadic type of Burkitt lymphoma (also known as "non-African") is the most common variant found in places where malaria is not endemic such as North America and parts of Europe. (wikipedia.org)
  • Burkitt lymphoma (BL) is an aggressive B-cell malignancy with endemic, sporadic and immunodeficiency-associated variants. (bmj.com)
  • Burkitt lymphoma (BL) can be classified into three forms which differ in geographic distribution and Epstein-Barr virus (EBV) association: endemic (eBL), sporadic (sBL) and HIV-associated BL ( table 1 ). (bmj.com)
  • It is a high-grade B-cell non-Hodgkin's lymphoma with endemic, sporadic and human immunodeficiency-associated subtypes. (bvsalud.org)
  • In sporadic (non-African) Burkitt lymphoma , abdominal disease predominates, often arising in the region of the ileocecal valve or the mesentery. (msdmanuals.com)
  • Less than 10% of cases present with central nervous system involvement, which usually manifest as cranial nerve palsies or spinal cord compression. (wikipedia.org)
  • EBV is detected in 25-40% of cases and common areas of involvement include GI tract, lymph nodes and bone marrow with 20-30% of affected people having central nervous system involvement. (wikipedia.org)
  • 25 patients (33%) presented or developed evidence of central nervous system involvement. (edu.gh)
  • DLBCL typically has larger cells, but some Burkitt lymphoma (BL) cases might have centroblast-like (large) cells intermixed with the more common medium-sized monoclonal lymphocytes, resulting in some degree of a diagnostic dilemma, especially when considering that up to 15% of DLBCL cases might test positive for the c- myc translocation. (medscape.com)
  • This type of translocation is seen in 15% of cases of Burkitt lymphoma. (wikipedia.org)
  • This type of translocation is involved in about 5% of cases of Burkitt lympohoma. (wikipedia.org)
  • Earlier in the day Professor Dalla-Favera gave the Burkitt Lecture "Molecular Genetics of Aggressive B Cell Lymphoma: from the Burkitt Translocation to Genome Sequencing" as a key-note talk at the Cancer Drug Discovery Day at Trinity Biomedical Sciences Institute. (tcd.ie)
  • BL is a rare, mature B-cell lymphoma molecularly defined by translocation of the proto-oncogene MYC. (cancernetwork.com)
  • These cases seem to represent a distinct biological phenomenon, in which a MYC translocation may be acquired at an immature stage of differentiation, thus manifesting features of both B-ALL/LBL and Burkitt lymphoma. (ipathology.cn)
  • P. Connor Johnson, MD, and Jeremy S. Abramson MD, MMSc, discuss available treatments for patients with Burkitt lymphoma and high-grade B-cell lymphoma. (cancernetwork.com)
  • This article reviews the current data and future directions in the management of Burkitt lymphoma (BL) and high-grade B-cell lymphoma (HGBL). (cancernetwork.com)
  • 1 A significant minority of these cases were the especially aggressive B-cell lymphomas Burkitt lymphoma (BL) and high-grade B-cell lymphoma (HGBL), the latter of which includes the histologic subtypes HGBL with MYC and BCL2 and/or BCL6 translocations (conventionally referred to as double-hit lymphoma [DHL]) and HGBL, not otherwise specified (NOS). (cancernetwork.com)
  • Hematoxylin and eosin-stained sections (original magnifications X20, X100 and X400) show a lymphoid proliferation of small B-cells with a widely monotonous growth pattern, suggestive for high-grade B-cell lymphoma. (biomedcentral.com)
  • He is the author of 200 publications and the co-editor of the textbook "Non Hodgkin Lymphoma" (Lippincott, Williams & Wilkins publishers). (tcd.ie)
  • Coexisting and clonally identical classical Hodgkin lymphoma and nodular lymphocyte predominant Hodgkin lymphoma. (cityofhope.org)
  • Nodal involvement by cutaneous CD30-positive T-cell lymphoma mimicking classical Hodgkin lymphoma. (cityofhope.org)
  • Aberrant T-Cell Antigen Expression in Classical Hodgkin Lymphoma is Associated with Decreased Event-Free Survival and Overall Survival. (cityofhope.org)
  • Non-Hodgkin lymphoma (NHL) is the seventh most common cancer in the United States, with approximately 77,000 new cases and 20,000 deaths in 2020. (cancernetwork.com)
  • For other discussions on lymphoma, see the overview topic Non-Hodgkin Lymphoma . (medscape.com)
  • Lymphoma was the second most common malignancy accounted for 22% of pediatric cases, of which 34 (68%) were non-Hodgkin?s lymphoma (NHL). (ijmpo.org)
  • Burkitt lymphoma is an aggressive B-cell non-Hodgkin lymphoma occurring in children and adults. (msdmanuals.com)
  • The major types are Hodgkin lymphoma Non-Hodgkin lymphoma See table Comparison of Hodgkin. (msdmanuals.com)
  • REAL/WHO- [6] - classification includes leukemias and lymphomas, with 3 categories based on lineage and morphology (Hodgkin, B cell, and T/NK cell). (oncolink.org)
  • The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA. (lookformedical.com)
  • The frequency of cutaneous lymphomas is 0.3 case per 100,000 population per year, with 10% (in the United States) to 20% (in Europe) being cutaneous B-cell lymphomas (CBCLs), marginal zone lymphomas, or follicle center lymphomas (FCLs). (medscape.com)
  • Marginal zone B-cell lymphoma (MZL) (MALT-type) is an indolent cutaneous lymphoma, accounting for approximately 10% of all cutaneous lymphomas. (medscape.com)
  • Safety and efficacy of combination therapy with fludarabine, mitoxantrone, and rituximab followed by yttrium-90 ibritumomab tiuxetan and maintenance rituximab as front-line therapy for patients with follicular or marginal zone lymphoma. (rush.edu)
  • Persistent infection with H. pylori induces atrophic gastritis and intestinal metaplasia, and subsequently leads to gastric malignancies including gastric carcinoma and extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma). (spandidos-publications.com)
  • Burkitt lymphoma (BL) must be distinguished from other primary abdominal tumors in childhood, including Wilms tumor , neuroblastoma , and peripheral neuroectodermal tumor . (medscape.com)
  • The tumor cells have a similar appearance to the those of the classical endemic Burkitt lymphoma. (wikipedia.org)
  • He is also utilizing multi-immunofluorescence to study the tumor microenvironment in lymphomas to better understand the dynamics and interactions of the cellular subsets and correlate with response to therapies. (cityofhope.org)
  • The tumor type and the extent of cutaneous involvement are the 2 most relevant prognostic factors in primary CBCL. (medscape.com)
  • abstract = "Data addressing prognostication in patients with HIV related Burkitt lymphoma (HIV-BL) currently treated remain scarce. (nebraska.edu)
  • Then, his research has continued to yield new insights into the pathogenesis of human B cell lymphomas, and, in particular, on the identification of the genetic lesions and biological mechanisms responsible for the development of these diseases. (tcd.ie)
  • The aggressive B-cell lymphomas BL, DHL, and HGBL, NOS are unique diseases with specific pathogenesis and biology. (cancernetwork.com)
  • B-cell lymphomas account for the majority of nodal lymphomas, whereas primary cutaneous B-cell lymphomas (CBCLs) represent 20-25% of all cutaneous lymphomas. (medscape.com)
  • In addition, cytoplasmic vacuoles are not uncommon in large cell lymphomas involving body cavities. (cytojournal.com)
  • The mutational landscape in Burkitt lymphoma has recently been found to differ between tumors with and without EBV infection, further strengthening the role of the virus in disease origin. (wikipedia.org)
  • Overview of Lymphoma Lymphomas are a heterogeneous group of tumors arising in the reticuloendothelial and lymphatic systems. (msdmanuals.com)
  • To find the incidence, clinical presentations, laboratory findings, proportion of extranodal involvement, and to study histological subtypes (REAL/WHO classification) of NHL, compare them with reported case series in the world literature. (ijmpo.org)
  • Aim Primary central nervous system lymphoma (PCNSL) is a rare extra nodal non-Hodgkin's lymphoma. (thieme-connect.com)
  • Primary central nervous system lymphoma (PCNSL) is a rare and aggressive extra nodal non-Hodgkin's lymphoma (NHL). (thieme-connect.com)
  • The Non-Hodgkin's lymphomas (NHL) comprise a diverse collection of lymphoreticular neoplasms, usually but not necessarily arising in nodal tissue. (oncolink.org)
  • The National Cancer Institute's Working Formulation, originally proposed in 1982, classified and grouped lymphomas by morphology and clinical behavior (ie, low, intermediate, or high grade) with 10 subgroups labeled A to J. (medscape.com)
  • The Working Formulation, originally proposed in 1982, classified and grouped lymphomas by morphology and clinical behavior (ie, low, intermediate, or high grade) with 10 subgroups labeled A to J.{Ref 1} In 1994, the Revised European-American Lymphoma (REAL) classification attempted to apply immunophenotypic and genetic features in identifying distinct clinicopathologic NHL entities. (medscape.com)
  • Differentiating between low-grade lymphoma and reactive lymphocytes is often difficult by morphology alone as reactive lymphoid cells may acquire activation morphology from being exposed to different cytokines within the body fluid. (cytojournal.com)
  • B Lymphoblastic Leukemia/Lymphoma With Burkitt-like Morphology and IGH/MYC Rearrangement: Report of 3 Cases in Adult Patients. (ipathology.cn)
  • The leukemic and lymphoma cells in all 3 cases demonstrated Burkitt lymphoma-like morphology with deeply basophilic cytoplasm and numerous cytoplasmic vacuoles. (ipathology.cn)
  • Diseases formerly designated as reticulosis or reticulosarcomatosis are currently classified according to the World Health Organization (WHO)/European Organization for Research and Treatment of Cancer (EORTC) classification (WHO-EORTC classification) for primary cutaneous lymphomas and the WHO classification. (medscape.com)
  • The abdominal region is the most common site of involvement, often at the right lower quadrant. (wikipedia.org)
  • Cutaneous lymphomas represent a unique group of lymphomas and are the second most frequent extranodal lymphomas. (medscape.com)
  • The development of cutaneous lymphoma is only partially understood. (medscape.com)
  • There is a low background incidence of BL worldwide (sBL), which is rarely associated with EBV and accounts for 1-2% of adult lymphoma in Western Europe and America, but eBL is associated with (EBV) in over 95% of cases and is predominant in the equatorial belt of Africa and other parts of the world where malaria is hyperendemic. (bmj.com)
  • Burkitt lymphoma (BL), in spite of its low incidence throughout most of the world, has had a major impact upon the understanding and treatment of lymphomas and doubtless upon many other cancers. (hindawi.com)
  • Burkitt lymphoma is a cancer of the lymphatic system, particularly B lymphocytes found in the germinal center. (wikipedia.org)
  • The 2015 Burkitt Medal was awarded to Riccardo Dalla-Favera, Professor of Pathology & Cell Biology, Director, Institute for Cancer Genetics at Columbia University, New York, USA, at a celebratory dinner on September 15th 2015 as part of Cancer Week Ireland events at Trinity College Dublin. (tcd.ie)
  • In Africa he developed exceptional observational and analytical skills which led him to develop a successful treatment for the commonest childhood cancer in Sub Saharan Africa - Burkitt lymphoma. (tcd.ie)
  • My discoveries that changed the ways to think about cancer, I believe, are: the demonstration of the juxtaposition of the MYC oncogene to the immunoglobulin loci and its dysregulation in Burkitt lymphoma, the first demonstration of the specific gene alterations in human cancer. (grantome.com)
  • In comparison to adults, the childhood lymphomas showed a number of notable differences with respect to sex distribution, site of involvement and histologic type. (nih.gov)
  • Isolated MYC rearrangement without other recurrent genetic abnormalities is rare in B lymphoblastic leukemia/lymphoma (B-ALL/LBL), with most cases reported in pediatric patients. (ipathology.cn)
  • Results: Lymphomas were the commonest cancers (49.5). (bvsalud.org)
  • All types of Burkitt lymphoma are characterized by dysregulation of the c-myc gene by one of three chromosomal translocations which place the myc gene under the control of an immunoglobulin gene enhancer. (wikipedia.org)
  • In the present review we highlight the latest findings on EBVaGC from clinicopathological and molecular perspectives to provide a better understanding of EBV involvement in gastric carcinogenesis. (spandidos-publications.com)
  • There is a well-characterized association of gastric lymphoma with Helicobacter pylori infection. (oncolink.org)
  • BACKGROUND: Patients with newly diagnosed high-risk Burkitt lymphoma are treated with high-intensity immune-chemotherapy regimens such as R-CODOX-M/R-IVAC or with lower-intensity regimens such as DA-EPOCH-R. The aim of this study was to make a formal comparison between these regimens. (bvsalud.org)
  • Five were Mediterranean-type lymphomas associated with plasma cell infiltration of the adjacent mucosa, and only two cases of primary Hodgkin's disease were encountered. (nih.gov)
  • It is an aggressive form of non-Hodgkin's B-cell lymphoma, usually diagnosed in children and young adults, but also seen rarely in middle-aged adults (1-3). (bvsalud.org)
  • Primary non-Hodgkin's lymphoma of the ovary is a rare occurrence. (biomedcentral.com)
  • Burkitt lymphoma is commonly associated with the infection of B cell lymphocytes with the EBV and in these cases is considered to be one form of the Epstein-Barr virus-associated lymphoproliferative diseases. (wikipedia.org)
  • Several studies 10 7 5 4 and a recent meta-analysis 1 have described a decrease in rates of CNS relapse in the post-rituximab era (probably due to improved control of systemic lymphoma), in addition to a change in the pattern of CNS relapse, with predominance of parenchymal over leptomeningeal relapse, isolated over combined (systemic plus CNS) relapses, and delayed CNS relapses. (haematologica.org)
  • two of the three patients who died from their disease in this series had non-B cell PCNSL, whereas only one patient with DLBCL died because of brainstem involvement. (thieme-connect.com)
  • Large cell lymphoma and leukemia cells tend to have large size nuclei, less mature chromatin, and visible nucleoli with and without cytoplasmic vacuoles. (cytojournal.com)
  • Nodular lymphomas comprised 10% of the total, nodular poorly differentiated lymphocytic lymphoma forming the majority of this group. (nih.gov)
  • Impact of cachexia on outcomes in aggressive lymphomas. (rush.edu)