Investigated the effects schwann cells. Medical search. Frequent questions

We transfected Schwann cells (SCs) that did not have differentiation ability with MPH 86 plasmid containing SV40T, in order to explore the effects of SV40T on Schwann cells. (ehu.eus)
Co-culturing with NSCs induced differentiation of the SV40T-SCs into neuronal and glial cells. (ehu.eus)
Therefore, the MAPK family governs almost all the physiological functions and processes such as cell adaptation, proliferation, differentiation, survival, and programmed cell death. (spandidos-publications.com)
Notch pathway activation promotes the differentiation of beagle dog periodontal ligament stem cells to Schwann cells. (edu.pl)
Periodontal ligament stem cells (PDLSCs) have demonstrated the potential for differentiation into many cell types, though the molecular mechanism of their neural differentiation in particular remains largely unknown. (edu.pl)
The Notch signaling pathway plays a key role in regulating cell differentiation and development. (edu.pl)
In this article, we explore its potential role in the differentiation of PDLSCs to Schwann cells (SCs). (edu.pl)
The potential effects of Notch signaling on myelination and SCs differentiation were then investigated using western blotting, immunostaining and reverse transcriptase polymerase chain reaction (RT-PCR) to detect the expression of SC-specific marker genes. (edu.pl)
Specifically inhibiting Notch signaling with DAPT decreased the expression of SC-specific marker genes GFAP , S100 and P75 , as well as of SC-myelin-related genes PMP22 , MBP , connexin, and P0 in cells undergoing induced differentiation from PDLSCs. (edu.pl)
Conversely, activating Notch signaling through overexpression of Delta ligands enhanced the expression of SC-specific marker genes as well as myelin-related genes in cells undergoing induced differentiation from PDLSCs. (edu.pl)
In this study, we investigate whether the Notch signaling pathway is involved in the differentiation of PDLSCs to SCs. (edu.pl)
Co-transplantation of schwann cells promotes the survival and differentiation of neural stem cells transplanted into the injured spinal cord[J]. Dev Neurosci, 2005, 27(1):20-26. (sdu.edu.cn)
However, the underlying mechanisms related to paracrine effect or the differentiation of transplanted cells into neurogenic or angiogenetic cells are still not well understood. (biomedcentral.com)

Conclusions: SV40T reprograms Schwann cells to stem-like cells at the stage of neural crest cells (NCCs) that can differentiate to neurocytes. (ehu.eus)
Human dental pulp stem cells can differentiate into Schwann cells and promote and guide neurite outgrowth in an aligned tissue-engineered collagen construct in vitro . (open.ac.uk)
MVSCs expressed markers such as Sox 17 and Sox10 and could differentiate into neural cells in vitro. (biomedcentral.com)
In vivo investigation has shown that MVSCs can be activated by vascular injuries, become proliferative, and differentiate into smooth muscle cells (SMCs). (biomedcentral.com)
The NSCs can grow and multiply in vitro medium, and then be activated to differentiate into different nerve cells to be transplanted within the brain to replace damaged cells. (biomedcentral.com)

Schwann cells (SCs) have important roles in development, myelination and regeneration in the peripheral nervous system. (scirp.org)
Early steps in myelination in the central nervous system (CNS) include a specialized and extreme form of cell spreading in which oligodendrocytes extend large lamellae that spiral around axons to form myelin. (rupress.org)

Satellite glial cells (SGCs) are among the most abundant non-neuronal cells in dorsal root ganglia (DRGs) and closely envelop sensory neurons that detect painful stimuli. (iasp-pain.org)
The present study aimed to investigate whether the protective effect of vitexin protects against sevoflurane-induced neuronal apoptosis and the underlying mechanisms of this protective effect. (spandidos-publications.com)
Together, the results of the current study suggest that the protective effect of vitexin reduces sevoflurane‑induced neuronal apoptosis through HIF‑1α‑, VEGF‑ and p38‑associated signaling pathways in newborn rats. (spandidos-publications.com)
We also investigated the effects of BotoxA-induced paralysis on the sprouting capacity of NMJs in the K108N-SEMA3A mutant mouse, and observed no change in the differential neuronal plasticity found at NMJs on fast-fatigable or slow muscle fibers due to the presence of the SEMA3A mutant protein. (nih.gov)
In the present study, the mechanistic role of Foxc1 on microglial migration, neuroinflammation and neuronal apoptosis during the occurrence of cognitive dysfunction in SAE was investigated. (spandidos-publications.com)
Lipopolysaccharide (LPS) treatment was found to trigger BV‑2 cell migration, inflammation and neuronal apoptosis. (spandidos-publications.com)
After Foxc1 was overexpressed, the cognitive dysfunction of mice that underwent CLP surgery was improved, with the expression of IκBα also increased, microglial cell migration, the expression of p65, IL‑1β and TNF‑α and neuronal apoptosis were all decreased in vivo and in vitro , which were in turn reversed by the inhibition of IκBα in vitro . (spandidos-publications.com)
5] Schmalenberg K E, Uhrich K E. Micropatterned polymer substrates control alignment of proliferating Schwann cells to direct neuronal regeneration[J]. Biomaterials, 2005, 26(12):1423-1430. (sdu.edu.cn)
In this regard, the growth and proliferation of the neural stem cells in vitro are critical as the number of cells available for transplantation is essential to achieve beneficial effect in replacing injury or loss of the neuronal cells. (biomedcentral.com)
Neuronal survival, axonal regeneration, and ultrastructural changes at ventral spinal cord were also investigated. (hindawi.com)

Co-transplantation of neural stem cells and Schwann cells within poly (L-lactic-co-glycolic acid) scaffolds facilitates axonal regeneration in hemisected rat spinal cord[J]. Chin Med J, 2013, 126(5):909-917. (sdu.edu.cn)
Co-transplantation of neural stem cells and NT-3-overexpressing Schwann cells in transected spinal cord[J]. J Neurotrauma, 2007, 24(12):1863-1877. (sdu.edu.cn)
The spinal cord is the thick bundle of cells and tissues that extends from the brain through the spine. (coursehero.com)
The peripheral nervous system (PNS) is the collection of nerves outside the brain and spinal cord that extends to the rest of the body and includes not just nerves, but also clusters of neuron cell bodies called ganglia or soma. (coursehero.com)
We hypothesized that shock wave treatment also may have a beneficial effect on spinal cord ischemia. (joinsoftwave.com)

A microglia‑mediated inflammation model was induced by LPS in BV‑2 microglial cells in vitro , whilst a SAE‑related cognitive impairment model was established in mice using cecal ligation and perforation (CLP) surgery. (spandidos-publications.com)
The human-on-a-chip neuromuscular system is an in vitro platform with superoxide dismutase (SOD1) (E100G) or TAR DNA binding protein (TDP-43) motoneurons derived from iPSCs and wild-type (WT) microglia separated by microtunnels from iPSC-derived SOD1 (E100G) skeletal muscle, Schwann cells, and THP-1 monocytes/macrophages. (mdaconference.org)
A 3D in vitro model reveals differences in the astrocyte response elicited by potential stem cell therapies for CNS injury. (open.ac.uk)
The cytocompatibility of PLGA scaffolds coated with different concentration of chitosan with schwann cells in vitro[J]. Chin J Aesth Med, 2009, 18(11):1627- 1631. (sdu.edu.cn)
He innovatively designed a three-dimensional bilayer hydrogel tri-culture system, which can accurately reproduce the structure and function of motor units in vitro, by sequentially co-culturing and differentiating myoblasts, Schwann cells, and motor neurons on two specific hydrogel substrates. (tmu.edu.tw)
These MVSCs can be differentiated into neural cells and mesenchymal cells in vitro. (biomedcentral.com)
NSCs can be cultured in vitro as neurospheres that are composed of neural stems cells and progenitors. (biomedcentral.com)
α2β1γ1) stimulates oligodendrocytes to extend elaborate membrane sheets in vitro (cell spreading), mediated by integrin α6β1. (rupress.org)

These studies began with promoter mapping for glial-specific genes (P0 and GFAP), and then progressed to oncogene-induced transformation and toxin-induced cell ablation of glia. (ehu.eus)
The neuromuscular junction (NMJ) is a tripartite synapse comprised of an α-motor neuron (the presynapse), extrafusal muscle fiber (the postsynapse), and specialized synaptic glia called perisynaptic Schwann cells (PSCs) or terminal Schwann cells. (elifesciences.org)

Here, using a genetic model of Schwann cell ablation, we find that Schwann cell loss results in transient PNS demyelination without overt axonal loss. (biorxiv.org)
Ablation of Schwann cells results in transient PNS demyelination, without overt axonal loss. (biorxiv.org)

By identifying similar reprograming in non-injured, demyelinated neurons, our study suggests that this reprograming represents a non-cell autonomous transcriptional response of sensory neurons to the loss of axon-Schwann cell interactions. (biorxiv.org)
His work deals with themes such as Schwann cell, Axon and Meningoencephalitis, which intersect with Virus. (research.com)

For GFAP, an intermediate filament of astrocytes, we have investigated the effects of alterations in gene dosage, both in terms of deficiency or excess of this structural protein. (ehu.eus)
Ongoing projects focus on glial cells (astrocytes and microglia) and how they coordinate with immune cells from the blood to affect bystander brain injury in the days after stroke. (stanford.edu)

We decided to use the three-dimensional culture of Schwann cells differentiated from endometrial stem cell in fibrin gel. (scirp.org)
These novel differentiated cells in fibrin gel might open new opportunities for the management of cell survival and neurotrophic potential in tissue engineering approaches for nerve repair. (scirp.org)
This paper presents our study on bioprinting Schwann cell-laden scaffolds from low-viscosity hydrogel compositions including RGD modified alginate, hyaluronic acid and fibrin, with a focus on investigating the printability of hydrogel compositions and characterizing the functions of printed scaffolds for potential use in nerve tissue regeneration. (desktopmetal.com)
Fibrin sealant has been applied in neurosurgery for decades, being effective and biocompatible, with no side effects to the nervous system microenvironment [ 21 ]. (hindawi.com)

0 Microscopic Study of the Intrapancreatic Ganglia and Its effect on the Endocrine 1 and Exocrine Part of Rat pancreas 2 Abstract 3 Background: Pancreas is an important endocrine and exocrine organ which plays a mandatory 4 role in nutritional hemostasis. (myessaywriters.co)

Schwann cells, the main glial cell in the peripheral nervous system (PNS), ensheath bundles of small unmyelinated axons or form myelin on larger axons. (biorxiv.org)
MVSCs facilitated the recruitment of Schwann cell to regenerated axons. (biomedcentral.com)
The transplanted cells, traced by GFP, differentiated into perineurial cells around the bundles of regenerated myelinated axons. (biomedcentral.com)
13 Results: The intrapancreatic ganglia were detected as groups of nerve cells and axons in the 14 connective tissue between the pancreatic acini of the rat pancreas. (myessaywriters.co)

Effects of melatonin on superovulation and transgenic embryo transplantation in small-tailed han sheep (Ovis aries). (nel.edu)
Transplantation of a multipotent cell population from human adipose tissue induces dystrophin expression in the immunocompetent mdx mouse[J]. J Exp Med, 2005, 201(9):1397-1405. (sdu.edu.cn)
In recent years, it has been an active research area to replace neural tissue loss through transplantation of neural stem cells (NSCs) for the treatment of AD [ 3 ]. (biomedcentral.com)

Engineered neural tissue with aligned, differentiated adipose-derived stem cells promotes peripheral nerve regeneration across a critical sized defect in rat sciatic nerve. (open.ac.uk)
Several types of stem cells have been explored for peripheral nerve regeneration (PNR), including umbilical cord blood stem cells, bone marrow-derived stem cells, adipose-derived stem cells, and neural stem cells [ 5 ]. (biomedcentral.com)

Methods: SCs were transfected with MPH 86 plasmid carrying the SV40T gene and cultured in different media, and also co-cultured with neural stem cells (NSCs). (ehu.eus)
Establishing this model not only helps scientists better understand the disease's progression but can also be used to test the effects of new drugs or treatment methods on neuromuscular units. (tmu.edu.tw)

Therefore, we explored the possibility that a unique combination of glial cell markers could be used to distinguish PSCs. (elifesciences.org)

Aligned Schwann cells derived from human dental pulp stem cells direct neurite growth in a tissue engineered collagen construct. (open.ac.uk)

Satellite cells (SCs), which are precursors of skeletal muscles, such as the TA muscle, play a key role in muscle homeostasis and regeneration. (biomedcentral.com)

It has been postulated that stimulation of PDC and respiratory chain activity by DCA in normally glycolytic Schwann cells causes uncompensated oxidative stress from increased reactive oxygen species production. (srcinhibitors.com)
Lithium and valproate acid protect NSC34 cells from H2O2-induced oxidative stress and upregulate expressions of SIRT3 and CARM1. (nel.edu)
Wang J, Feng H, Zhang J, Jiang H. Lithium and valproate acid protect NSC34 cells from H2O2-induced oxidative stress and upregulate expressions of SIRT3 and CARM1. (nel.edu)

To examine the effect of BDNF on F-actin during the stimulation of IL-1β in hippocampal neurons. (nel.edu)
Synchronous contractions of ALS-like disease and WT model systems at various stimulation frequencies can also be investigated using this model. (mdaconference.org)
The sequence of contraction and relaxation is linked to changes in the motor system and its ability to respond to stimulation, and this could have implications for treatments for depression and stroke that excite nerve cells. (womenshealthdaily.com)
These organic conductors provide safe electrical stimulation of tissue while avoiding undesirable chemical reactions and cell damage. (frontiersin.org)

An international team has shown that the injection of a type of stem cell into the brains of patients living with progressive multiple sclerosis (MS) is safe, well tolerated and has a long-lasting effect that appears to protect the brain from further damage. (womenshealthdaily.com)
9] Alessandri G, Emanueli C, Madeddu P. Genetically engineered stem cell therapy for tissue regeneration[J]. Ann N Y Acad Sci, 2004, 1015:271-284. (sdu.edu.cn)
Stem cell therapy is a promising approach to promote neural tissue regeneration. (biomedcentral.com)
Primary neural stem cells were prepared from the hippocampus of newly born SD rats, and cells were cultured in special stem cell culture medium. (biomedcentral.com)
Incubation of cells with icariin resulted in significant increase in the number of stem cell spheres as well as the increased incorporation of EdU when compared with cells exposed to control vehicle. (biomedcentral.com)
This study evidently demonstrates the potentiating effect of ICA on neural stem cell growth and proliferation, which might be mediated through regulation of cell cycle gene and protein expression promoting cell cycle progression. (biomedcentral.com)

This review focuses on studies of Schwann cell and astrocyte biology and pathology. (ehu.eus)
The tri-culture system can be used to investigate the basic biology of motor units and explore the pathologic mechanisms of NMDs, aiding in developing new therapeutic strategies. (tmu.edu.tw)
Dr. Franco aims to apply her expertise in redox biology and cell metabolism to the field of NF type 2 (NF2). (health.mil)
She was introduced to the field by Dr. Cristina Fernandez-Valle, an expert in NF2 and Schwann cell biology and a close collaborator and mentor. (health.mil)

Objective To investigate cytocompatibility of the electron spinning chitosan-PLGA nerve conduits with Schwann cells (SCs)and neural stem cells(NSCs) as well as cells adhesion and migration on the arranged nanofibers inside the lumen. (sdu.edu.cn)

In this paper, the geographical distribution, chemical components, traditional therapeutic effect, pharmacological activities, and biosynthetic pathways of TAs in Solanaceous plants were summarized. (bvsalud.org)
In this paper, the geographical distribution, chemical components, traditional therapeutic effect, and modern pharmacological activities of TAs-containing species in Solanaceae were analyzed for the first time. (bvsalud.org)
Since miRNAs have potency in the management of diseases by regulating the expression level of target mRNAs in eukaryotic cells, targeting PMP22 with its specific miRNA might be a therapeutic option for controlling disease caused by PMP22 overexpression. (en-journal.org)
However, preclinical models to evaluate the effect of the complement system and potential therapeutic interventions on NMJ function are necessary. (mdaconference.org)
We investigated the therapeutic potential of conditioned medium (CM) derived from stem cells from human exfoliated deciduous teeth (SHED-CM) against NP using a mouse partial sciatic nerve ligation (PSL) model. (tokushima-u.ac.jp)
The functional motor recovery and cell fate in the regenerated nerve were investigated to understand the therapeutic benefit. (biomedcentral.com)
These adult stem cells have demonstrated promising therapeutic benefits with less concerns about ethics, regulation, and tumor formation, as compared to embryonic stem cells. (biomedcentral.com)
In vivo therapeutic effects, including functional recovery and cell fate, were investigated. (biomedcentral.com)

Background: The specific effect of SV40T on neurocytes has seldom been investigated by the researchers. (ehu.eus)
Researchers have recently investigated how damaged nerves can regenerate better. (womenshealthdaily.com)
These effects, the researchers say, are separate from those caused by general stress and depression. (womenshealthdaily.com)
However, it also prevents most medicines from reaching the brain and thus represents a major challenge for pharmaceutical researchers when investigating treatments of neurological disorders. (coursehero.com)

The Schwann cells (SCs) are a glial nerve cell type that form an important part of the Ruffini body of periodontal nerve endings, and play an important role in growth, development and regeneration of peripheral nerves. (edu.pl)

Monitoring neuron and astrocyte interactions with a 3D cell culture system. (open.ac.uk)

PNS injuries initiate transcriptional reprograming in both Schwann cells and sensory neurons that promotes regeneration. (biorxiv.org)
VEGF is purified from bovine pituitary follicular cells in 1959 and is a vascular endothelial cell-specific mitogen that promotes the growth of vascular endothelial cells. (spandidos-publications.com)
The present study showed that icariin promotes the growth and proliferation of neural stem cells from rat hippocampus in a dose-dependent manner. (biomedcentral.com)

We use basic and clinical research to understand the cells, proteins, and genes that lead to successful recovery of function, and also how complications develop that impact quality of life after stroke. (stanford.edu)
Further, the mechanism of ICA-induced cell proliferation of neural stem cells was investigated by analyzing the gene and protein expression of cell cycle related genes cyclin D1 and p21. (biomedcentral.com)
In addition, it was found that icariin-induced effect on neural stem cells is associated with increased mRNA and protein expression of cell cycle genes cyclin D1 and p21. (biomedcentral.com)

Usually, however, peripheral nerve injuries are classified in five stages, based on the extent of damage to both the nerve and the surrounding connective tissue, since supporting glial cells may be involved. (wikipedia.org)

In addition, the addition of VEGF to the culture medium can increase the survival rate of neurons in the cerebral cortex as well as the number and length of ganglion cell processes, to promote nerve growth. (spandidos-publications.com)
Results Cell survival rate of the co-culture group was the highest, the higher in the SCs group, and the lowest in the NSCs group. (sdu.edu.cn)
Using human and mouse cell culture models of NF2 in combination with intracellular cell signaling arrays and metabolic profiling, she proposes to determine the metabolic phenotype of NF2-associated schwannoma cells, then identify the signaling pathways that are regulated by tyrosine nitration and how they promote schwannoma cell proliferation and survival. (health.mil)

AIM: Although the Tiger-Gian formula (TGF) has proven clinically effective at improving the symptoms of knee osteoarthritis (KOA), the pharmacological effects and underlying mechanisms of TGF have not been examined in any animal model. (bvsalud.org)
The objective of this study was to elucidate the effects of early bFGF administration on the thyroarytenoid muscle after RLN transection and to investigate the underlying mechanisms. (biomedcentral.com)

Single-Cell Analysis of Dorsal Root Ganglia Reveals Metalloproteinase Signaling in Satellite Glial Cells and Pain. (iasp-pain.org)

Gelatin methacryloyl (GelMA)/Chitosan Microspheres (GC-MSs) were prepared by a microfluidic approach, and the effect of these microspheres on enhancing neurite outgrowth and elongation of PC12 cells was demonstrated. (desktopmetal.com)

OBJECTIVE: This study investigated the efficacy of acupuncture in preventing chemotherapy-induced peripheral neuropathy (CIPN) in patients with colorectal cancer (CRC). (bvsalud.org)
This study assessed the effects of TGF in male Sprague-Dawley rats with anterior cruciate ligament transection (ACLT) -induced KOA. (bvsalud.org)
In this study, we investigate the expression of differentiated Schwann cell markers by exposing of endometrial stem cells with induction media including FGF2/FSK/HRG/RA. (scirp.org)
The study of PSCs has relied on an anatomy-based approach, as the identities of cell-specific PSC molecular markers have remained elusive. (elifesciences.org)
In our previous study, we found that periodontal ligament stem cells (PDLSCs) isolated from beagle dogs effectively differentiated into SCs with exposure to a combination of dimethyl sulfoxide (DMSO), basic fibroblast growth factor (bFGF), brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF) and forskolin. (edu.pl)
In this study, the effects of melatonin on superovulation and the transfer of transgenic embryos were investigated in Small-Tai. (nel.edu)
Purpose: The study investigated the effect of Botulinum toxin A on the gait and lower limb muscle activity of ambulatory CP children. (iospress.com)
We show that human and mouse inner ear cells have the molecular machinery to allow SARS-CoV-2 entry," wrote the study authors. (iflscience.com)
The purpose of this study was to investigate the potentiating effect of ICA on the proliferation of rat hippocampal neural stem cells, and explore the possible mechanism involved. (biomedcentral.com)
His Rabies study incorporates themes from Ecology, Adverse effect, Incidence and Disease surveillance. (research.com)

Terminal Schwann cells (TSCs) are specialized cells that envelop the motor nerve terminal, and play a role in the maintenance and regeneration of neuromuscular junctions (NMJs). (nih.gov)

By profiling sensory ganglia at single-cell resolution we show that this demyelination induces transcriptional reprogramming preferably in proprioceptive and Aβ RA-LTMR neurons. (biorxiv.org)

While the factors that initiate the transcriptional reprograming in Schwann cells are well characterized, the full range of stimuli that initiate this reprograming in sensory neurons remain elusive. (biorxiv.org)
Transcriptional reprograming is assumed to be a cell autonomous response of sensory neurons to mechanical axonal injury. (biorxiv.org)
Schwann cell loss results in transcriptional reprograming in specific sensory neurons. (biorxiv.org)
Lithium and valproic acid (VPA) have been reported to produce antioxidant effects by increasing the transcriptional coactivator. (nel.edu)

Critical to the hypothesis is the experimental fact that human endometrial-derived stem cells (hEnSCs) as multipotent accessible source of cells are known as useful cell candidates in the field of nerve tissue engineering. (scirp.org)
They found that fat tissue strongly supports the Schwann cells needed for repair during the healing process. (womenshealthdaily.com)
Tissue and Cell Engineering Society Annual Conference 2014 , 2-4 Jul 2014, Newcastle, p. 29. (open.ac.uk)
A neuron is a cell in the nervous tissue that transmits electrical and chemical signals throughout the body. (coursehero.com)

The proliferation of these cells was detected by WST-1, and the expression of different biomarkers was analyzed by qPCR and immunohistochemistry.Results: SV40T induced the characteristics of NSCs, such as the ability to grow in suspension, form spheroid colonies and proliferate rapidly, in the SCs, which were reversed by knocking out SV40T by the Flip-adenovirus. (ehu.eus)
A single, early local administration of high-dose bFGF prevented atrophic changes in the thyroarytenoid muscles by activating satellite cell proliferation and reforming neuromuscular junctions. (biomedcentral.com)
The effect of ICA on the growth and proliferation of the neural stem cells was evaluated by 5-ethynyl-2-deoxyuridine (EdU) labeling of proliferating cells, and photomicrographic images of the cultured neural stem cells. (biomedcentral.com)
Exploring the effect of pharmacological manipulation, such as usage of traditional medicine, on the growth and proliferation of neural stem cells is thus valuable towards the development of the stem cells therapies of the neurodegenerative disorders. (biomedcentral.com)

Immunohistochemistry indicated that bFGF significantly increased the number of satellite cells in the thyroarytenoid muscle up to day 14 and that of neuromuscular junctions on days 28 and 56. (biomedcentral.com)

Purpose: We evaluated the effects of the drug MS-818 (2-piperadino-6-methyl-5-oxo-5,6-dihydro-(7H) pyrrolo-[3,4-d] pyrimidine maleate), a synthesized pyrimidine compound, on regeneration in crush-injured sciatic nerves of rats. (iospress.com)
NGF peptide levels retained in the crushed nerves of rats 5 days after surgery and in the culture medium of IMS32 cells, a mouse Schwann cell line, incubated for 24 h with high or low doses of MS-818, were measured by enzyme immunoassay. (iospress.com)

Biopsychosocial Factors Associated with Pain and Pain-Related Outcomes in Adults and Children with Sickle Cell Disease: A Multivariable Analysis of the GRNDaD Multi-Center Registry. (iasp-pain.org)
Pain is the primary symptomatic manifestation of sickle cell disease (SCD), an inherited hemoglobinopathy. (iasp-pain.org)

These cells also expressed NSC markers like Nestin, Sox2, CD133 and SSEA-1, as well as early development markers of embryonic stem cells (ESCs) like BMP4, c-Myc, OCT4 and Gbx2. (ehu.eus)

Neural stem cells were confirmed by immunofluorescence detection of nestin, NSE and GFAP expression. (biomedcentral.com)

Forkhead box C1 (Foxc1) is a member of the forkhead transcription factor family that has been found to regulate in cell migration. (spandidos-publications.com)
Scanning electron microscopy(SEM) was used to detect cells adhesion and migration on the axially arranged nanofibers inside the lumen. (sdu.edu.cn)
Conclusion Co-culture of SCs and NSCs can facilitate cells compatibility and adhesion with 3D Chitosan-PLGA, and the axial arranged nanofibers within the lumen has the effect of directional guide cell growth and migration. (sdu.edu.cn)

All these characteristics have made SCs the first and the most widely used support cells to be used for peripheral nerve regeneration. (edu.pl)

effect of chronic DCA exposure and experimental data implicate the Schwann cell as a toxicological target. (srcinhibitors.com)

And finally, route three gets us in the primary afferent auditory and/or vestibular nerve cells. (iflscience.com)
The nervous system is composed two types of cells: of various types of neurons (nerve cells) with specialized functions and different kinds of glial (support and protective) cells. (coursehero.com)

CONCLUSION: Prophylactic acupuncture may exert neuroprotective effects on mechanical or tactile touch thresholds during chemotherapy regimens in patients with CRC, with evidence of this protectiveness persisting at 6 months' follow-up. (bvsalud.org)
The lack of change in motor NCV values with verum acupuncture indicates neuroprotective effects. (bvsalud.org)

Background The serine-threonine protein kinase mammalian target of rapamycin (mTOR), which is definitely inhibited from the immunosuppressant drug rapamycin regulates several intracellular pathways in response to numerous extracellular signals, nutrient availability, energy status of the cell and stress. (researchensemble.com)

In recent years, the MAPK family has been found to be an important signal-regulating enzyme between cell surface receptors and determinants of gene expression ( 8 ). (spandidos-publications.com)

A neuroglia is a cell that supports and protects neurons in the central nervous system. (coursehero.com)

Pharmacological treatment of AD such as acetylcholinesterase inhibitors and NMDA channel blocker has some beneficial effects on cognitive and behavioral symptoms, but it does not stop or reverse the progression of the disease [ 2 ]. (biomedcentral.com)

During the development of peripheral nervous system, the importance of miRNAs has been investigated. (en-journal.org)
A growing number of molecular markers that recognize subsets of glial cells throughout the nervous system have been identified ( Jäkel and Dimou, 2017 ). (elifesciences.org)
Phagocytic microglial cells and the thick-walled capillaries of the blood-brain barrier maintain a sterile central nervous system in healthy individuals. (coursehero.com)
A microglial cell is a phagocytic cell within the nervous system that seeks out and destroys any pathogens that manage to cross from the circulatory system into the nervous system. (coursehero.com)

Anatomy22

Organisms6

Diseases10

Chemicals and Drugs23

Analytical, Diagnostic and Therapeutic Techniques and Equipment8

Phenomena and Processes6

Disciplines and Occupations1

Differentiation13

Differentiate5

Myelination2

Neuronal10

Spinal cord5

Vitro8

Glia2

Ablation2

Axon2

Astrocytes2

Fibrin4

Abstract1

Axons4

Transplantation3

Adipose-derived stem cells2

Methods2

Glial cell1

Dental pulp stem cells1

Skeletal1

Oxidative stress3

Stimulation4

Stem Cell6

Biology4

Conduits1

Therapeutic8

Researchers4

Regeneration of peripheral1

Astrocyte1

Promotes3

Genes3

Injuries1

Survival3

Mechanisms2

Dorsal1

Elongation1

Study10

Terminal1

Demyelination1

Transcriptional4

Tissue4

Proliferation4

Neuromuscular1

Nerves2

Sickle cell di2

Embryonic stem1

GFAP1

Migration3

Peripheral nerve regeneration1

Experimental1

Nerve cells2

Neuroprotective effects2

Pathways1

Gene1

Neurons1

Pharmacological1

Nervous system4