Investigate cardiovascular physiological phenomena. Medical search. Frequent questions

Obesity is considered a clinical state of impaired general heath in which the excessive increase in adipose tissue mass may be associated with metabolic disorders such as type 2 diabetes mellitus, hyperlipidemia, hypertension and cardiovascular diseases. (uzh.ch)
Excessive proliferation of smooth muscle cells is a common phenomenon in diseases such as atherosclerosis, but the role of growth factors in the mechanism which modulate this process has yet to be clarified. (torvergata.it)
Immune dysregulation has been identified as a critical cause of the most common types of cardiovascular diseases (CVDs). (biomedcentral.com)
Many types of cardiovascular diseases (CVDs) are associated with complex immune responses that can significantly contribute to their progression and remission. (biomedcentral.com)
He is also designing a small diameter tissue engineered vascular graft to treat cardiovascular diseases. (pitt.edu)
Atherosclerosis is the main underlying pathology behind cardiovascular diseases (CVD), which is a major cause of disability and premature death in the world. (upm.edu.my)

His research focused on his core belief that much of cardiovascular disease arises from psychosocial factors, and is hence potentially preventable or treatable by modifying these. (wikipedia.org)
A number of studies have investigated chronic psychosocial factors and acute physiological responses to laboratory-induced stress in healthy populations [1]. (scirp.org)

Hence, even though physiological and pathophysiological phenomena are well described in dogs and cats, the underlying mechanisms are often not known and studies investigating causality specifically are scarce. (uzh.ch)
Results could provide a better understanding of the mechanisms of these adaptations on long-duration missions and support development of methods for assessing cardiovascular and respiratory effects on blood pressure before and after spaceflight. (nasa.gov)
The principal objective of our research is to investigate the mode, dynamics and mechanisms of leukocyte transmigration, the final stage in the leukocyte adhesion cascade, that describes the movement of leukocytes from the vascular lumen into inflamed and/or injured tissues. (qmul.ac.uk)
In this project, independent researchers are investigating three mechanisms that are likely involved in glucose regulation by the liver. (bcm.edu)
Thus, we believe poor sleep quality is one of the core mechanisms in dawn phenomenon. (hindawi.com)
These molecules play a crucial role across a broad range of physiological mechanisms. (lifeextension.com)
In this study, we performed a literature review in order to investigate the relationship between auditory mechanisms and cardiac autonomic regulation. (bvsalud.org)

Circadian clock has a vital impact on the regulation of physiological and biochemical processes, cellular and energy metabolism, glucose and lipid homeostasis, and feeding behavior. (hindawi.com)
Taurine , one of the most abundant amino acids in humans, plays a vital role in various physiological processes. (worldhealth.net)

Some endogenous hormones, especially growth hormone, cortisol, and glucagon, also take part in the pathophysiological mechanism of dawn phenomenon [ 4 , 5 ]. (hindawi.com)
Furthermore, the precise pathophysiological characteristics underlying the association of different cardiovascular risk factors in MetS remain elusive [ 5 ]. (biomedcentral.com)

Astronauts experience changes in their cardiovascular, respiratory, and musculoskeletal systems during spaceflight, which can affect their capacity to exercise and to maintain blood pressure when standing after return to Earth. (nasa.gov)

BACKGROUND: Pregnancy is a physiological state during which inflammation occurs. (bvsalud.org)
Collectively through the application of molecular and cellular assays, and advanced imaging platforms, our work aims to unravel previously unexplored cellular and molecular physiological concepts and identify disease-specific phenomena in immunity, inflammation and vascular biology. (qmul.ac.uk)
Notably, the innate and adaptive immune responses under physiological conditions are typically regulated with high sensitivity to avoid the exacerbation of inflammation, but any dysregulation can probably be associated with CVDs. (biomedcentral.com)

The findings from the final experiment indicated that "cleaning behavior results in a more adaptive profile of cardiovascular reactivity," the researchers said. (psypost.org)
Investigating abnormal cell behavior provides crucial information about disease development and progression. (filosofia-internet.net)
2023. Housing conditions affect adult zebrafish (Danio rerio) behavior but not their physiological status. (awionline.org)

He was an internationally renowned expert in clinical hypertension and a leader in the fields of hypertension and cardiovascular behavioral medicine. (wikipedia.org)
Here he undertook a program of research on behavioral aspects of hypertension and cardiovascular disease. (wikipedia.org)

The participants were told that the researchers were interested in understanding more about physiological responses to intellectual and academic tasks. (psypost.org)
But prayer is more than just repetition and physiological responses, says Harold Koenig, MD, associate professor of medicine and psychiatry at Duke and a colleague of Krucoff's. (godsaidmansaid.com)
Evoked responses and ongoing oscillations represent two major electrophysiological phenomena in the human brain yet the link between them remains rather obscure. (researchgate.net)

Further studies are necessary to add new elements in the literature to improve new therapies to treat cardiovascular disorders. (bvsalud.org)

This is the first report on the physiological role of CysLT(2), and the findings suggest that CysLT(2) has biological significance in the cardiovascular system. (nih.gov)
The process and potential to slow it down have captivated the scientific community prompting a substantial rise in research to enhance our understanding of aging as a biological phenomenon. (worldhealth.net)
Aging is a biological and psychological phenomenon that affects the family and social level. (bvsalud.org)
social and biological phenomena. (who.int)

We employ models for analysis of both physiologically relevant as well as pathological inflammatory models and a key component of our work is a research programme that investigates how pathological inflammatory insults impact the dynamics of neutrophil-vessel wall interactions and the implications of disrupted modes of neutrophil transmigration (e.g. neutrophil reverse transendothelial cell migration) on inflammatory disease development and dissemination. (qmul.ac.uk)
In particular, it plays a vital role in the physiological and pathological activities of the three important cells, Endothelial cells, macrophages and vascular smooth muscle cells. (wjgnet.com)

Pickering continued his work as Director of the Integrative and Behavioral Cardiology Program at Mount Sinai Hospital in New York City in 2000, finally relocating to Columbia University Medical Center in New York City in 2003 to form the Center for Behavioral Cardiovascular Health where he worked until his death in 2009. (wikipedia.org)
Although he participated in a great deal of physiological research early in his career, Pickering's research in behavioral determinants and consequences of hypertension formed the heart of the program. (wikipedia.org)
Pickering was the Principal Investigator of a National Heart Lung and Blood institute Program Project that began in 1993 and has investigated several phenomena related to the behavioral causes and physiological consequences of hypertension, focusing on white coat hypertension, nocturnal blood pressure "dipping", race differences in PSG-assessed sleep quality and target organ damage, and the effects of work-related stress on blood pressure and left ventricular hypertrophy (LVH). (wikipedia.org)
HRF-1 provides an on-orbit laboratory that enables scientists conducting human life science research to evaluate the physiological, behavioral, and chemical changes induced by space flight. (nasa.gov)
Thus, the measurement of dynamic changes in the concentration of extracellular AVP in distinct brain areas under defined experimental conditions would provide a missing link for the physiological involvement of the endogenous neuropeptide in the regulation of autonomic, endocrine, and behavioral parameters. (jneurosci.org)

Acute stress responsivity (including stress reactivity and recovery of hypothalamic-pituitary-adrenal [HPA] axis, autonomic, and cardiovascular systems) as well as disturbances in immune regulation as a result of stress has been examined in healthy subjects [1-3]. (scirp.org)
Cardiobreath studies the combined effects of cardiovascular and respiratory adaptations on blood pressure regulation during spaceflight. (nasa.gov)

Scientists have discovered that fucoidans are a source of necessary components of cell-surface molecules that facilitate cell-to-cell signaling, the core regulatory process responsible for everything from immunity and cardiovascular function to healthy cellular proliferation. (lifeextension.com)

However, the physiological role for this channel in cardiac function remains unclear. (frontiersin.org)

The mechanism of dawn phenomenon still remains unclear. (hindawi.com)
Although the influence of different range of motions and muscle-tendon unit lengths has been investigated in pure stretch-hold experiments in vivo, the contribution to a SSC movement in human muscles remains unclear. (nature.com)

In fact, the last decade has been rich in illustrating the possible roles played by apelin in human physiology, namely as a regulating peptide of cardiovascular, hypothalamus-hypophysis, gastrointestinal, and immune systems. (nih.gov)
Stress coping models or process models have shown that the strain associated with caregiving can result in psychological distress and interference with the immune system (8) and cardiovascular functions (6,7). (cdc.gov)

To achieve this goal, we employ a multi-disciplinary approach to investigate the associated molecular and cellular pathways involved in neutrophil-vessel wall interactions. (qmul.ac.uk)
Indeed, IS is a very complex phenomenon which is influenced not only by the cellular metabolic status but also interacts with circulating molecules such as hormones (including insulin), nutrients and inflammatory molecules. (biomedcentral.com)

The possible involvement of apelin in the pathogenesis of high prevalence conditions and comorbidities - such as hypertension, heart failure, and Diabetes Mellitus Type 2 (T2DM) - rank it as a likely therapeutic target to be investigated in the future. (nih.gov)
The levels of HbA1c and fasting glucose and the magnitude of dawn phenomenon were significantly higher in the diabetes group with poor sleep quality than that with good sleep quality. (hindawi.com)
Dawn phenomenon mostly affects children and youth with type 1 diabetes, although it is not rare in subjects with type 2 diabetes (as high as 40%, reported by Monnier et al. (hindawi.com)
Furthermore, fasting glucose levels are one of the most important targets in the management of type 2 diabetes, and these can be affected by the dawn phenomenon. (hindawi.com)
Since diabetes is associated with cardiovascular and kidney complications, we investigated the influence of SBE on blood glucose, blood pressure and renal function in some experimental animal paradigms. (endocrine-abstracts.org)
Furthermore, severe PE is a major cause of maternal morbidity (i.e., stroke and liver rupture) and negative long-term outcomes (i.e., cardiovascular disease and diabetes mellitus) as well as adverse perinatal effects, such as prematurity and intrauterine growth restriction [ 5 , 10 ]. (hindawi.com)

To assess their roles, we investigated the distribution of their receptors, CysLT(1) and CysLT(2), in the cardiovascular system. (nih.gov)
These three phenomena indicate that receptors are highly dynamic molecules and sample several active and inactive states stochastically (for review, see refs. (nature.com)

Additionally, we collected parameters associated with metabolic health in obesity (waist-hip ratio, waist-height ratio, leptin levels, body fat percentage, fat mass index, insulin resistance) to investigate recently proposed mechanistic explanatory models of why olfaction may be altered in obesity. (frontiersin.org)
Patients with metabolic syndrome (MetS) have an increased risk of cardiovascular disease. (biomedcentral.com)

A key approach is the application of confocal intravital microscopy that enables rigorous and direct means of investigating the interactions of leukocytes with different components of microvessel walls (endothelial cells, pericytes and the vascular basement membrane) in real-time in vivo. (qmul.ac.uk)

Objective 2, containing three components, will determine the role of leptin and the leptin receptor in hepatic gluconeogenesis and investigate the nutritional significance of certain small molecules in reducing glucose production via gluconeogeneic pathway. (bcm.edu)
The effects of emotional stressors on the release of arginine vasopressin (AVP) and oxytocin (OXT) within the rat hypothalamus and the origin and physiological significance of AVP released within the hypothalamic paraventricular nucleus (PVN) were investigated. (jneurosci.org)

Research has advanced our knowledge of physiological, biomechanical, and the psychological aspects of physical training and performance. (lww.com)
Aging is a physiological process that involves all living things and is connected to the loss of skills, the way of life in the past, genetics, and emotional and psychological changes. (bvsalud.org)
Significant correlation with measures of psychological and physiological health also reflected positively on the criterion-related validity of the scale. (scielo.org.za)
Non-Traditional Immersive Seminar Enhances Learning by Promoting Greater Physiological and Psychological Engagement Compared to a Traditional Lecture Format. (stanford.edu)

The magnitude of dawn phenomenon was quantified by its increment from nocturnal nadir to prebreakfast. (hindawi.com)
2 ]. By using a continuous glucose monitoring system, dawn phenomenon could be determined by the difference between nocturnal nadir and prebreakfast glucose levels [ 2 ]. (hindawi.com)

International Scientific Advisory Board of the Institute of Cardiovascular Science, University of Birmingham (2023 to date). (qmul.ac.uk)

The present paper is an overview of apelin physiologic effects and presents the possible role played by this peptide in the pathogenesis of a number of conditions as well as the therapeutic implications that might, therefore, be investigated. (nih.gov)
For example, Järup and Akesson (2009) recently reviewed the literature on cadmium and health effects and identified single-study-reported associations between cadmium and cardiovascular effects other than HTN. (nih.gov)
In addition to the gender and age, the use of medications containing side effects of xerostomia/dry mouth/ hyposalivation or hyposialia was investigated. (bvsalud.org)
The objective of the study was to investigate the effects of housing (deep litter + concrete floor vs. deep litter + ground soil with the possibility to dig burrows), and genotype (Mecklenburg or Hyplus) on. (awionline.org)
This present study aimed to investigate the anti-atherosclerotic, hypocholesterolemic, changes in the erythrocyte antioxidant enzymes, hepatoprotective and toxicity effects of the aqueous extract of the leaves of Anacardium occidentale Linn. (upm.edu.my)
These results provide an important validation of source-localized fNIRS in the context of concurrent multimodal imaging for future studies of the relationship between physiological effects in the human brain. (humanconnectome.org)
These compounds replicate the physiological effects of fasting by activating similar molecular pathways. (healthnews.com)

Training in its simplest form represents acute challenges to the body intended to optimize chronic improvements in physiological capabilities. (lww.com)

Aim of the present study was to investigate the possible involvement of ANF on rat aortic smooth muscle (RASM) cells proliferation induced by known mitogens and the mechanism involved. (torvergata.it)
Our data show that ANF, at physiological concentration range, inhibits RASM cell proliferation induced by known mitogens such as PDGF and insulin, and the effect seems to be elicited through the modulation of phosphatidic acid (PA) production and MAP kinases involvement. (torvergata.it)

In their fourth and final experiment, the researchers also found physiological evidence to support their hypothesis. (psypost.org)

Urbanization as a global phenomenon led to the restructuring of the nature of cities and, as a consequence, caused unfavorable health and well-being conditions 1 1. (scielosp.org)
der the supervision of the Directorate is a global phenomenon reflecting the Malnutrition is common among of Social Security in Lattakia, which is increase in life expectancy that has residents of homes for the elderly and under the Ministry of Social Security. (who.int)
INTRODUCTION: While waterpipe tobacco smoking has become a global phenomenon, its potential health consequences are poorly understood. (who.int)

Material and methods: 235 elderly were investigated, of both sexes, of which 123 were women (52.3%) and 112 (47.7%) were men. (bvsalud.org)

We also work on algorithms for simulations of various phenomena in physics and physiology. (lu.se)

Hypertension (HTN) and smoking are established risk factors for cardiovascular disease ( U.S. Department of Health and Human Services 2000 ), the leading cause of death worldwide ( World Health Organization 2009 ). (nih.gov)
It is well-documented that abnormally high levels of IGF-1, seen in acromegaly, are associated with higher mortality and a higher prevalence of cancer and cardiovascular disease. (brinkzone.com)
If low IGF-1 levels are associated with an increased risk of developing cardiovascular disease and high IGF-1 levels are associated with an increased risk of developing cancer, there might be an optimal set point for the GH/IGF-1 axis associated with increased longevity. (brinkzone.com)
A notable study investigated the relationship between IGF-1 levels and all-cause/cause-specific mortality, cardiovascular disease and cancer, in a national representative sample of community-dwelling older persons over 65 years of age. (brinkzone.com)
This study found no significant associations were found between IGF-1 levels and nonfatal cardiovascular disease and fatal and nonfatal cancer. (brinkzone.com)
Cardioprotective Properties: The amino acid has been associated with improved cardiovascular health, including reduced risk of heart disease and enhanced heart function. (worldhealth.net)
Particular reference will be made to new work exploring the of association of CWP with cardiovascular disease. (upf.edu)

Such drugs were separated according to their medical area of expertise: Cardiology, Gastroenterology, Allergy, Neurology and pulmonology Results: When investigated the amount of drugs used for female patients, it was observed that 83 (67.5%) used up to five drugs, 35 (28.4%) between 6 and 10 and medicines, and 5 (4.1%) more than 10 drugs. (bvsalud.org)

Even some drug companies are investigating their therapeutic potential. (lifeextension.com)

It is generally believed that dawn phenomenon is a result of pancreatic beta-cell dysfunction, which increases endogenous glucose production, persistent insulin resistance, and hepatic glucose output. (hindawi.com)

Since a body of literature implies that olfactory perception and function is hampered in obesity, we here investigate neuroanatomical correlates of this phenomenon. (frontiersin.org)

GH and IGF-1 levels are reduced with normal aging, a phenomenon called somatopause. (brinkzone.com)
Aging brings forth many physiological changes across various levels, from organelles to organ systems. (worldhealth.net)

This Summer School provides a thorough overview and hands-on experience in state-of-the-art Virtual Physiological Human (VPH) research. (upf.edu)

We recorded concurrent fNIRS with magnetoencephalography (MEG) and functional magnetic resonance imaging (fMRI) in order to investigate the group-level correspondence of these measures with source-localized fNIRS estimates. (humanconnectome.org)

Microgravity offers the opportunity to investigate such "wet" foams, which cannot be stabilized on Earth because of drainage. (nasa.gov)
This project-based course offers students an opportunity to investigate and explore the fundamental principles of environmental science and the numerous related issues caused by human activity. (aps1.net)

Poor sleep quality was significantly correlated with magnitude of dawn phenomenon. (hindawi.com)
Multiple linear regression showed that sleep quality and PER1 were significantly independently correlated with dawn phenomenon. (hindawi.com)
Average time spent over 65% of max heart rate, energy expenditure, total bounds, mechanical and physiological load were significantly greater in the immersive seminar group when compared to traditional lecture format. (stanford.edu)

He was the Chair of the Bioengineering Division of the American Society of Mechanical Engineers (ASME), the first non-MD President of the International Society for Applied Cardiovascular Biology, and the Secretary of the Executive Committee of the Biomedical Engineering Society (BMES), for which he served on the Board of Directors for 10 years. (pitt.edu)
2012) Elected President, International Society for Applied Cardiovascular Biology (ISACB). (pitt.edu)
2006) Named to Executive Council of the International Society for Applied Cardiovascular Biology (ISACB). (pitt.edu)

This study aimed to further investigate this condition. (go.jp)
Objective: This study aimed to investigate drugs with potential xerostomic effect in institutionalized elderly patients. (bvsalud.org)

Au total, 103 personnes âgées dans trois maisons de retraite ont été interrogées en entretien individuel en recourant à la version en langue arabe de l'échelle d'évaluation de l'état nutritionnel Mini Nutritional Assessment (MNA) , et des mesures anthropométriques ont été réalisées pour évaluer leur état nutritionnel. (who.int)
The homes are sponsored by Among the many health issues being go unrecognized because the anthro- charities and donors and the services investigated, the nutritional status of the pometric parameters of elderly people provided to residents include housing, elderly population has gained attention. (who.int)

The use of back belts may produce temporary strain on the cardiovascular system. (cdc.gov)
One cryoEM and over 50 high-resolution X-ray crystallographic structures are available for antagonist- or agonist-bound A 2A AR and for its ternary complex with an agonist and an engineered G protein, making this receptor an excellent model system for investigating GPCR structural dynamics. (nature.com)
The literature has already demonstrated that auditory stimulation with music influences the cardiovascular system. (bvsalud.org)

Physical activity predicts reduced plasma β amyloid in the Cardiovascular Health Study. (humanconnectome.org)
Using longitudinal data from the Cardiovascular Health Study, we examined whether PA predicted plasma Aβ levels and risk for cognitive decline 9-13 years later. (humanconnectome.org)

The VPH Summer School series is co-organized by the Barcelona MedTech - Universitat Pompeu Fabra and by the Virtual Physiological Human Institute . (upf.edu)

published that the approximate impact of the dawn phenomenon on HbA1c level was 0.4% and the impact for averaged 24 h mean glucose concentrations was 12.4 mg/dL [ 3 ]. (hindawi.com)

A more than 2-fold increased risk of cardiovascular mortality was found for both low-normal (239% increased risk) and high-normal (203 % increased risk) IGF-1 levels. (brinkzone.com)
It is interesting that having low-normal IGF-1 levels impose a greater risk of all-cause mortality and cardiovascular mortality than having high-normal IGF-1 levels. (brinkzone.com)

Increasing student capacity to critically analyze and relate phenomena of the physical world in terms of the fundamental laws of physics is the underlying objective of this course. (aps1.net)

Fever may also be related to necrotic-inflammatory phenomena of the tumor and/or to alterations in liver function and consequent disorders of steroidogenesis. (medscape.com)

Diseases1

Phenomena and Processes29

Diseases6

Psychosocial factors2

Mechanisms7

Processes2

Pathophysiological2

Musculoskeletal1

Inflammation3

Behavior3

Hypertension and cardiovascular2

Responses3

Treat cardiovascular1

Biological4

Pathological2

Behavioral5

Regulation2

Immunity1

Cardiac1

Remains unclear2

Immune2

Cellular2

Diabetes6

Receptors2

Metabolic2

Vascular1

Significance2

Psychological4

Nocturnal2

20231

Effects7

Chronic1

Involvement2

Researchers1

Global phenomenon3

Methods1

Physiology1

Disease7

Cardiology1

Therapeutic1

Insulin resistance1

Obesity1

Aging2

Research1

Order to investigate1

Opportunity to investigate2

Significantly3

Biology3

Study aimed2

Nutritional2

System3

Health2

Human1

Level1

Risk2

Terms1

Function1