• Data was compiled from Glasgow, the United States, and the Netherlands over a long period and led to a series of papers in the 1970s, the introduction of the near universally adopted Glasgow Coma Scale (GCS) with Graham Teasdale, and the Glasgow Outcome Scale with Bond. (wikipedia.org)
  • Diagnosis of SAH usually depends on a high index of clinical suspicion combined with radiologic confirmation via urgent noncontrast CT, followed by lumbar puncture or CT angiography of the brain. (medscape.com)
  • This can be applied in a clinical setting to find locations of abnormalities as well as in an experimental setting to simply measure brain activity. (wikipedia.org)
  • These radiographic findings in hypertensive encephalopathy, posterior reversible encephalopathy syndrome, and reversible posterior leukoencephalopathy syndrome supported the concept that the syndrome results from fluid and protein extravasation across the blood-brain barrier, owing to failure of cerebral autoregulation. (medlink.com)
  • In the late 1980s and early 1990s a number of non-selective partial agonists, exemplified by bretazenil, pazinaclone and abecarnil, were described. (hhs.gov)
  • In 1976 there was furore over a BBC Panorama Programme which questioned the criteria for the establishment of brain death in potential organ donors. (wikipedia.org)
  • Prior to moving to Glasgow, Jennett published work on epilepsy following head injuries. (wikipedia.org)
  • This was cumbersome, and, in the 1980s, MEG manufacturers began to arrange multiple sensors into arrays to cover a larger area of the head. (wikipedia.org)
  • His work with the Glasgow-based Neuropathologists Adams and Graham significantly reduced mortality and disability. (wikipedia.org)
  • In 2012, it was demonstrated that MEG could work with a chip-scale atomic magnetometer (CSAM, type of SERF). (wikipedia.org)
  • Small-caliber low velocity bullets may intersect skull base, causing significant damage to the brain and a communication between endocranium and paranasal sinuses. (surgicalneurologyint.com)
  • [1] [2] Applications of MEG include basic research into perceptual and cognitive brain processes, localizing regions affected by pathology before surgical removal, determining the function of various parts of the brain, and neurofeedback . (wikipedia.org)
  • This is irreversible brain damage," Omalu said. (dogbrothers.com)
  • 34 35 64 ] ICP >20 mmHg is considered to be elevated, and this is considered an important cause of secondary injury leading to irreversible brain injury and death. (surgicalneurologyint.com)
  • traumatic brain injury, intracerebral hemorrhage, subarachnoid hemorrhage, hydrocephalus, malignant infarction, cerebral edema, CNS infections, hepatic encephalopathy, to name a few, and in all of these conditions ICP monitoring in the light of other parameters can influence management for better outcomes. (surgicalneurologyint.com)
  • Hospital complications that further increased the risk of dying in multivariable analysis included rebleeding, global cerebral edema, hypernatremia, clinical signs of brain stem herniation, hypotension of less than 90 mm Hg treated with pressors, pulmonary edema, myocardial ischemia, and hepatic failure. (medscape.com)
  • His work with the Glasgow-based Neuropathologists Adams and Graham significantly reduced mortality and disability. (wikipedia.org)
  • Admission predictors of mortality were age, loss of consciousness at ictus, admission Glasgow Coma Scale score, large aneurysm size, Acute Physiology and Chronic Health Evaluation II (APACHE II) physiologic subscore, and Modified Fisher Scale score. (medscape.com)
  • Strategies directed toward minimizing early brain injury and aneurysm rebleeding, along with prevention and treatment of medical complication, hold the best promise for further reducing mortality after SAH. (medscape.com)
  • [ 8 ] The International Cooperative Aneurysm Study, conducted in the 1980s, pointed to vasospasm, direct effects of the primary hemorrhage, and rebleeding as the most frequent causes of mortality after SAH. (medscape.com)
  • The images on the screen were of magnified brain tissue from her son, the former Pittsburgh Steelers offensive lineman Justin Strzelczyk, who was killed in a fiery automobile crash three years ago at age 36. (dogbrothers.com)
  • Bailes suggested to Omalu that Strzelczyk's brain tissue might be preserved at the local coroner's office, a hunch that proved correct. (dogbrothers.com)
  • Intracranial pressure (ICP) is defined as the pressure inside the skull, and therefore, the pressure inside the brain tissue and the cerebrospinal fluid (CSF). (surgicalneurologyint.com)
  • Prior to moving to Glasgow, Jennett published work on epilepsy following head injuries. (wikipedia.org)
  • In 1976 there was furore over a BBC Panorama Programme which questioned the criteria for the establishment of brain death in potential organ donors. (wikipedia.org)
  • Among those who died, brain death was declared in 42 %, 50 % were do-not-resuscitate at the time of cardiac death (86 % of whom had life support actively withdrawn), and 8 % died despite full support. (medscape.com)