• The ascorbate anion forms salts, such as sodium ascorbate, calcium ascorbate, and potassium ascorbate. (wikipedia.org)
  • However, intravenous sodium ascorbate (at least 180 grams per 24 hours) is an outstanding alternative. (naturalnews.com)
  • Klenner found that viral diseases could be cured by intravenous sodium ascorbate in amounts up to 200 grams per 24 hours. (doctoryourself.com)
  • The composition of the final product in 40 mL solution is fluoroestradiol no more than 5 μg, fluoroestradiol F 18 148 MBq/mL to 3,700 MBq/mL (4 mCi/mL to 100 mCi/mL), sodium ascorbate 0.44% w/v in sodium chloride 0.9% w/v, and ethanol no more than 3.2% w/v. (globalrph.com)
  • He was given an initial intravenous infustion of EDTA which consisted of 3.0 g EDTA (Keylate,r Edtite sodium, The Key Company), 15.0 g ascorbic acid buffered in sodium ascorbate (Bronson Pharmaceuticals), 800 mg magnesium chloride, 40.0 mg procaine and 1000 units of heparin delivered in 500 mL of sterile, deionized water. (orthomolecular.com)
  • For MDs to discuss IV/C and to help the public find medical professionals with experience giving I. V. sodium ascorbate. (vitamincfoundation.com)
  • Please vote on whether we should publish a list of doctors who provide intravenous (IV) vitamin C (sodium ascorbate). (vitamincfoundation.com)
  • These supplements typically include sodium ascorbate, ascorbic acid with bioflavonoids, ascorbyl palmitate, calcium ascorbate, or mineral forms of ascorbate. (livonlabs.com)
  • 500 mg of sodium ascorbate, several times a day. (livonlabs.com)
  • Sodium ascorbate is recommended most by vitamin C experts, and it is commonly used in high dose intravenous (IV) infusions. (livonlabs.com)
  • In 1949 Klenner published in and presented a paper to the American Medical Association detailing the complete cure of 60 out of 60 of his polio patients using intravenous sodium ascorbate injections. (crazzfiles.com)
  • WICHITA, Kan. , Feb. 26 /PRNewswire/ -- Bio-Communications Research Institute's (BCRI's) recent research study has found that high levels of vitamin C (ascorbate) inhibit the formation of new blood vessel growth to tumors. (prnewswire.com)
  • High levels of vitamin C saturation necessary for angiogenesis to occur are obtainable with the intravenous infusion of vitamin C (ascorbate). (prnewswire.com)
  • In a previous study (Sept, 2005) BCRI researchers found that intravenous infusions of vitamin C were selectively toxic to tumor cells. (prnewswire.com)
  • She is currently running both observational and interventional studies investigating the requirements for vitamin C in different disorders and the potential health effects of both oral and intravenous vitamin C. She is particularly interested in the role of vitamin C in the prevention and treatment of acute and chronic conditions such as severe infection, cancer and metabolic disorders. (otago.ac.nz)
  • She has also investigated the effects of intravenous vitamin C on cancer and chemotherapy-related symptoms and quality of life. (otago.ac.nz)
  • Such high, cancer-stopping levels of vitamin C can be "readily achieved in humans given ascorbate intravenously. (positivehealth.com)
  • Stressful conditions of any kind greatly increase utilization of vitamin C. Ascorbate excreted in the urine drops markedly with stresses of any magnitude unless vitamin C is provided in large amounts. (doctoryourself.com)
  • Irwin Stone (10, 11, 12) pointed out the potential of vitamin C in the treatment of many diseases, the inability of humans to synthesize ascorbate, and the resultant condition hypoascorbemia. (doctoryourself.com)
  • In those cases, high-dose intravenous ascorbate - a solution of vitamin C and a mineral - is suggested. (newmediaexplorer.org)
  • We hear that natural whole vitamin C is always the best source, food is always the best source, and the statement that people with illnesses can get enough ascorbate (vitamin C) from food. (healthimpactnews.com)
  • High dose vitamin C involves intravenous injections of vitamin C of up to 85 gm (depending upon body weight), every 5 days, for 8 rounds to increase 'Hydrogen Peroxide' levels in cells. (canceractive.com)
  • Intravenous vitamin C (IVC), vitamin C megadoses and cancer - a practical guide by Dr. Julian Kenyon of the Dove Clinic UK. (canceractive.com)
  • More correctly, High Dose vitamin C uses injections of ascorbate, and this acts as a pro-drug to increase H 2 O 2 in cancer cells and kill them. (canceractive.com)
  • They have conducted clinical research showing High dose vitamin C, delivered by the use of Intravenous vitamin C injections, significantly slows the rate of growth of cancer - either on its own, or in conjunction with chemotherapy and radiotherapy. (canceractive.com)
  • CW: So is intravenous vitamin C really an 'alternative' to conventional chemotherapy? (canceractive.com)
  • High dose intravenous vitamin C is one of these treatments, and we use it extensively in our clinic. (canceractive.com)
  • To obtain vitamin C at pro-oxidant levels, at which it destroys cancer cells, is only achievable by intravenous infusion. (canceractive.com)
  • This requires intravenous infusions of 75 grams of vitamin C, (in some cases less, depending on the size of the patient and the tumour cell mass), infused intravenously on a daily basis for three weeks in order to be able to attain these plasma levels. (canceractive.com)
  • Acetaminophen and Ascorbate in Sepsis: Targeted Therapy to Enhance Recovery (ASTER) - this trial assesses the efficacy of intravenous acetaminophen and vitamin C in improving the outcomes of patients with sepsis and either hemodynamic or respiratory organ failure. (uclahealth.org)
  • Knowledge of the known vitamin functions of ascorbate would not have allowed one to predict these beneficial results. (mall-net.com)
  • Once this happens, vitamin C (ascorbate) has to be ingested immediately to prevent sustained damage to the bones, the blood vessels, the network of nerves, and the brain. (zocalopublicsquare.org)
  • I.V. vitamin C corrects an ascorbate deficiency, often seen in cancer patients. (element7wellness.com)
  • High dose intravenous vitamin C (IVC) is used in the naturopathic cancer care. (boltonnaturopathic.ca)
  • To bypass this, vitamin C solution is infused through an intravenous catheter directly into the vein. (boltonnaturopathic.ca)
  • Intravenous vitamin C therapy is individualized to the patient, and depends on factors including cancer stage as well as any other treatments currently ongoing such as chemotherapy or radiation. (boltonnaturopathic.ca)
  • Two time Nobel Prize winner Dr. Linus Pauling studied the use of intravenous Vitamin C in cancer. (survivingmesothelioma.com)
  • This study found that ascorbate (Vitamin C) was toxic to mesothelioma cells. (survivingmesothelioma.com)
  • Vitamin C is also called L-ascorbic acid or ascorbate. (longlivinglife.com)
  • Vitamin C can be administered by intravenous infusion or orally. (longlivinglife.com)
  • When administered by intravenous (IV) infusion, vitamin C can reach higher levels in the blood than when taken orally. (longlivinglife.com)
  • Ascorbic acid, Ascorbate, or otherwise commonly known as vitamin C, plays a crucial role in various physiological processes, including iron metabolism. (pur-c.com)
  • Therefore, intravenous vitamin C can be used as an adjunct in the treatment of anemia in these patients, as safe, effective, and affordable therapy, with few known complications in hemodialysis patients. (pur-c.com)
  • What are the advantages and rewards of Replenish 360's IV Hydration Therapy focused on Wellness and Preventative intravenous (IV) or intramuscular (IM) services with Vitamin C or Ascorbic Acid? (yourcprmd.com)
  • While some health advocates recommend intravenous vitamin C for chronic illness (which I have used in my practice for many years), it is also effective in oral form for both treatment and prevention of colds and flu. (askdrmaxwell.com)
  • For my patients, I recommend supplementing vitamin C in the form of calcium ascorbate 500-1,000 mg. daily. (askdrmaxwell.com)
  • Diamond Nutritionals' Foundation Vitamins contain 500 mg. of calcium ascorbate vitamin C, along with a full-spectrum balance of other beneficial, immune-boosting vitamins and minerals. (askdrmaxwell.com)
  • The deprotonated conjugate base is the ascorbate anion, which is stabilized by electron delocalization that results from resonance between two forms: For this reason, ascorbic acid is much more acidic than would be expected if the compound contained only isolated hydroxyl groups. (wikipedia.org)
  • Nucleophilic attack of ascorbic acid on a proton results in a 1,3-diketone: The ascorbate ion is the predominant species at typical biological pH values. (wikipedia.org)
  • I needed learn a lot more about the intravenous delivery of this molecule known as ascorbic acid, or ascorbate. (naturalterrain.com)
  • He was then started on a series of 30 EDTA intravenous infusions administered at approximately weekly intervals over a period of seven months. (orthomolecular.com)
  • An article appearing in The Lancet, a British medical journal, on Feb. 21, 1920, titled: "Influentzal Pneumonia: The Intravenous Injection of Hydrogen Peroxide" tell of a remarkable recovery of a man in a coma near death who received a single injection of 3% hydrogen peroxide solution. (newmediaexplorer.org)
  • CERIANNA is a sterile, clear, colorless solution for intravenous injection, with an osmolarity of 340 mOsm. (globalrph.com)
  • The recommended amount of radioactivity to be administered for PET imaging is 222 MBq (6 mCi), with a range of 111 MBq to 222 MBq (3 mCi to 6 mCi), administered as a single intravenous injection of 10 mL or less over 1 to 2 minutes. (globalrph.com)
  • Mistletoe therapy can be done as a subcutaneous injection into the abdomen, or as an intravenous therapy. (boltonnaturopathic.ca)
  • However, if doses of ascorbate are not provided to satisfy this potential draw on the nutrient, first local tissues involved in the disease, then the blood, and then the body in general become deplete of ascorbate (ANASCORBEMIA and ACUTE INDUCED SCURVY). (doctoryourself.com)
  • Clinically, in a disease ameliorated by ascorbate, there is a suppression of symptoms only with very high doses and approximately to that extent which a nonrate-limited,_antioxidant_free_radical_scavenger, might be expected to affect that disease process if all harmful free radicals and highly reactive oxidizing substances were quenched. (mall-net.com)
  • Since even at very high doses, ascorbate is virtually nontoxic, it may be given in the enormous doses necessary to quench almost all unwanted free radicals and oxidants. (mall-net.com)
  • The wide spectrum of infectious diseases ameliorated by massive doses of ascorbate indicates some common pathologic processes in these diseases. (mall-net.com)
  • There was a remarkable lack of systemic difficulties in these patients that could be directly related to the massive doses of ascorbate. (mall-net.com)
  • Low or moderate doses (doses substantially below bowel tolerance) usually had no noticeable immediate beneficial effects, but high doses (doses just below the amount that would produce diarrhea in a patient tolerant to ascorbate) would have the effect of markedly suppressing symptoms as the high dose levels were reached. (mall-net.com)
  • There is evidence in the literature that high doses of ascorbate can reduce inflammatory cytokine levels in cancer patients. (rmiclinic.com)
  • Whereas nutrient absorption through the digestive system "maxes out" beyond certain levels, meaning that more cannot be absorbed, intravenous therapy delivers large doses of nutrients directly to the blood and to the cellular level directly. (boltonnaturopathic.ca)
  • The oxidized forms of ascorbate are relatively unreactive and do not cause cellular damage. (wikipedia.org)
  • [ 5 ] Only when the GI barrier is bypassed, such as by intravenous infusion or in the presence of advanced renal dysfunction, does aluminum have the potential to accumulate. (medscape.com)
  • Chelation therapy (both oral and intravenous) has been a critical treatment that has been available for biological toxicity due to heavy metals such as mercury, lead, cadmium, and so forth. (marionmedicalpc.com)
  • Mixtures of mineral ascorbates (calcium, magnesium, potassium, zinc, and sometimes sodium) are used in certain circumstances to increase bowel tolerance for even more clinical effectiveness but do not clearly demonstrate the increasing bowel tolerance phenomenon being discussed here. (mall-net.com)
  • More sensitive to hyperthermia and/or high-dose intravenous ascorbate. (compostasma.com)
  • mean weight, 68 3.3 kg) received a single oral dose of sodium nitrite at 0.06 or 0.12 mmol/mmol haemoglobin, corresponding to 140 190 mg or 290 380 mg, depending on the weight of the person, and 7 days later received one intravenous dose of sodium nitrite at 0.12 mmol/mmol haemoglobin, corresponding to 290 380 mg. (inchem.org)
  • plasma AscH - ] ≥≈20mM), achievable through intravenous delivery, oxidation of P-AscH - can produce a high flux of H 2 O 2 in tumors. (edzardernst.com)
  • Intravenous ascorbate as a tumor cytotoxic chemotherapeutic agent. (neilriordan.com)
  • Ascorbate deficiency, also known as Hypovitaminosis C, can affect serum ferritin concentration by hampering iron mobilization from storage sites, resulting in increased ferritin levels. (pur-c.com)
  • Ascorbate deficiency can have significant effects on serum ferritin concentration in patients with S-thalassemia major and iron overload. (pur-c.com)
  • In addition, studies have demonstrated that ascorbate deficiency alone is not the primary cause of iron overload in S-thalassemia major patients. (pur-c.com)
  • Moreover, ascorbate deficiency exacerbates the iron overload condition by impairing iron absorption and promoting iron retention in tissues, leading to increased serum ferritin levels. (pur-c.com)
  • Naturopathic intravenous therapy can be used to treat a variety of health conditions including fatigue, adrenal fatigue or "burnout," poor immunity and recurrent infections, chronic infections, liver conditions, to aid "detoxification" and elimination processes, to replete nutrient levels in patients with digestive problems, and in patients with cancer.Specific IV formulas are used depending on the patient's condition and state of health. (boltonnaturopathic.ca)
  • Ewan Cameron in association with Pauling (15, 16, 17) has shown the usefulness of ascorbate in the treatment of cancer. (doctoryourself.com)
  • However, a more convenient and clinically useful measure of ascorbate need and presumably utilization is the BOWEL TOLERANCE. (doctoryourself.com)
  • Ascorbate content of clinical glioma tissues is related to tumour grade and to global levels of 5-hydroxymethyl cytosine. (otago.ac.nz)
  • The deficit of ascorbate probably starts in the tissues directly involved in the disease and then spreads to other tissues of the body. (doctoryourself.com)
  • but if the ascorbate/dehydroascorbate (AA/DHA) ratio is kept high (the redox potential kept reducing) until the unstable dehydro- ascorbate undergoes hydrolysis or can be reduced back to ascorbate, the dehydroascorbate will do no harm. (mall-net.com)
  • Naturopathic intravenous therapy involves administering nutrients such as vitamins and minerals, as well as select naturally occurring antioxidants and herbal extracts directly to the bloodstream. (boltonnaturopathic.ca)
  • Intravenous administration of nutrients bypasses impaired gastrointestinal absorption and allows more rapid, effective delivery of nutrients. (boltonnaturopathic.ca)
  • Lactate, citrate, and ascorbate all facilitate GI absorption. (medscape.com)
  • Additionally, maintaining adequate ascorbate levels through dietary sources and daily supplementation can support iron absorption and mitigate further complications associated with iron overload. (pur-c.com)
  • However, being a good electron donor, excess ascorbate in the presence of free metal ions can not only promote but also initiate free radical reactions, thus making it a potentially dangerous pro-oxidative compound in certain metabolic contexts. (wikipedia.org)
  • When ascorbate levels are low, deficient, or depleted, the ability to convert ferric iron to ferrous iron is compromised. (pur-c.com)
  • Rather, in the context of iron overload, low ascorbate levels can contribute to elevated serum ferritin concentrations. (pur-c.com)
  • In order to achieve the concentrations necessary for this anticancer effect, intravenous administration is necessary. (boltonnaturopathic.ca)
  • The patient is thereby put at risk for complications of metabolic processes known to be dependent upon ascorbate. (doctoryourself.com)
  • A survey of college students in North America found 14 percent with ascorbate below the level for good health. (zocalopublicsquare.org)
  • Increased ascorbate content of glioblastoma is associated with a suppressed hypoxic response and improved patient survival. (otago.ac.nz)
  • If this massive draw on the small ascorbate stores of the body is not fully satisfied, the condition of ANASCORBEMIA results. (doctoryourself.com)
  • This increased bowel tolerance phenomenon serves not only to indicate the amount which should be taken but indicates the unsuspected and astonishing magnitude of the potential use that the body has for ascorbate under stressful conditions. (doctoryourself.com)
  • Using intravenous (IV) therapy is a fast and powerful way to deliver nutrients to the body. (element7wellness.com)
  • Ascorbate (AscH - ) functions as a versatile reducing agent. (edzardernst.com)
  • It is as if a threshold were reached at which point the ascorbate becomes very effective. (mall-net.com)