• The SCN‐activated, light‐inhibited production of melatonin conveys the message of darkness to the clock and induces night‐state physiological functions, for example, sleep/wake blood pressure and metabolism. (dailyrituals.de)
  • Metabolically inert infrastructure or buoyant force of fluids secludes self gravitating body from external stronger gravitational field and helps to maintain self gravity's free fall condition. (webmedcentral.com)
  • Clinically meaningful effects of melatonin treatment have been demonstrated in placebo‐controlled trials in humans, particularly in disorders associated with diminished or misaligned melatonin rhythms, for example, circadian rhythm‐related sleep disorders, jet lag and shift work, insomnia in children with neurodevelopmental disorders, poor (non‐restorative) sleep quality, non‐dipping nocturnal blood pressure (nocturnal hypertension) and Alzheimer's disease (AD). (dailyrituals.de)
  • Hydrocephalus, an excessive accumulation of cerebrospinal fluid in the brain that can cause increased pressure inside the head, is common in some of the mucopolysaccharidoses. (nih.gov)
  • An abnormal accumulation of cerebrospinal fluid within the ventricles of the brain that is acquired after birth. (nih.gov)
  • These are conditions in which large numbers of molecules that normally break down or degrade into smaller pieces in intracellular compartments called lysosomes accumulate in harmful amounts in the body's cells and tissues, particularly in the lysosomes. (nih.gov)
  • Body fluid compartments. (lookformedical.com)
  • However, it remains unclear whether KIT transduces signals from intracellular compartments in AML. (regenerativemedicine.net)
  • The two types of spaces between which water and other body fluids are distributed: extracellular and intracellular. (lookformedical.com)
  • Other variables include the pH of extracellular fluid , the concentrations of sodium , potassium , and calcium ions , as well as the blood sugar level , and these need to be regulated despite changes in the environment, diet, or level of activity. (wikipedia.org)
  • GAGs (formerly called mucopolysaccharides) are also found in the fluids that lubricate joints. (wikipedia.org)
  • Glycosaminoglycans (formerly known as mucopolysaccharides) are also found in the fluid lubricating our joints. (nih.gov)
  • Surgically inserting a shunt into the brain can drain fluid. (wikipedia.org)
  • Now, a group of scientists from Japan has aimed to answer this question by using a newly synthesized compound (along with other existing ones) that targets intracellular transport, which may offer an attractive strategy to combat cancer. (regenerativemedicine.net)
  • The research group from Japan aimed to answer this question by using a newly synthesized compound called M-COPA (along with other existing ones) that targets intracellular transport. (regenerativemedicine.net)
  • They did this by using specific compounds that target intracellular transport of proteins: brefeldin A (BFA), 2-methylcoprophilinamide (M-COPA) (inhibitors of transport from ER to the Golgi), and monensin (inhibitor of Golgi export). (regenerativemedicine.net)
  • Sugar feeding activates hormonal mechanisms, such as the secretion of insulin from the pancreas, but sugar levels are also monitored by the so called intracellular sugar sensors. (regenerativemedicine.net)