Corynebacterium pseudotuberculosis is a Gram-positive bacterium known globally to infect ruminants, horses, and rarely people. (wikipedia.org)
citation needed] Shortly after, it was sampled from abscesses in a sheep by Hugo von Preisz [hu], and the bacterium was named the "Preisz-Nocard" bacillus until further work by German microbiologists in the mid-1900s, when it was recategorized into the Corynebacterium genus. (wikipedia.org)
C. pseudotuberculosis is a Gram-positive bacterium that can be either coccoid or filamentous rods, which can be organized into palisades. (wikipedia.org)
This bacterium is grown at 37 °C under aerobic or anaerobic conditions, thus C. pseudotuberculosis is a facultative anaerobe. (wikipedia.org)
Comparative analyses of the exoproteomes of two C. pseudotuberculosis strains, in addition to comparison with other experimentally determined corynebacterial exoproteomes, were helpful to gain novel insights into the contribution of the exported proteins in the virulence of this bacterium. (biomedcentral.com)
The present study examined the possibilities that: (i) careful examination of Gram-stained sputum and culture plates may reveal a predominant bacterium such as Corynebacterium spp. (biomedcentral.com)
Human granulocytic anaplasmosis ( HGA ) is a tick-borne , infectious disease caused by Anaplasma phagocytophilum , an obligate intracellular bacterium that is typically transmitted to humans by ticks of the Ixodes ricinus species complex, including Ixodes scapularis and Ixodes pacificus in North America. (mdwiki.org)
Pathogens3
Corynebacterium pseudotuberculosis is a facultative intracellular pathogen that belongs to the so-called CMN ( Corynebacterium-Mycobacterium-Nocardia ) group, a distinct subgroup of the Actinobacteria that also includes other highly important bacterial pathogens, such as Corynebacterium diphtheriae and Mycobacterium tuberculosis . (biomedcentral.com)
Murine and in vitro experiments have shown that the expression/induction of T-bet, the master regulator of Th1 differentiation, can be achieved by obligate intracellular pathogens involved with lymphadenitis and by Kikuchi disease, suggesting the Kikuchi disease is somehow related to obligate intracellular pathogens. (medscape.com)
General Information: Bacteria belonging to the Chlamydiales group are obligate intracellular parasites of eukaryotic cells. (up.ac.za)
Caseous lymphadenitis2
In small ruminants, C. pseudotuberculosis causes a disease called caseous lymphadenitis characterized by pyogranulomatous abscess formation. (wikipedia.org)
citation needed] Distribution of C. pseudotuberculosis is mostly traced by examining prevalence of caseous lymphadenitis, the bacterium's main pathological disease. (wikipedia.org)
Lymphadenitis1
citation needed] C. pseudotuberculosis also causes disease in horses, and should be considered prevalent in areas where cases of "pigeon fever" and "ulcerative lymphadenitis" have been recorded. (wikipedia.org)
citation needed] Although few recent studies have been conducted into its prevalence, data from slaughterhouses in Australia in the late 1980s suggested that C. pseudotuberculosis was affecting 50-60% of sheep. (wikipedia.org)
Although prevalence of CL varies by region and country, it is found worldwide and is of major concern for small ruminant producers in North America. (msdvetmanual.com)
Diphtheriae2
Respiratory diphtheria is a serious infection caused by toxigenic Corynebacterium diphtheriae, and disease transmission mainly occurs through respiratory droplets. (cdc.gov)
Here we utilized whole-genome sequencing (WGS) to characterize recovered isolates of C. diphtheriae and two co-circulating non-diphtheritic Corynebacterium (NDC) species - C. pseudodiphtheriticum and C. propinquum. (cdc.gov)
Species1
citation needed] It was finally renamed Corynebacterium pseudotuberculosis in 1948, to reflect that the clinical disease signs were similar to disease caused by M. tuberculosis species. (wikipedia.org)
Strains2
44 proteins were commonly identified in two different strains, isolated from distinct hosts, then composing a core C. pseudotuberculosis exoproteome. (biomedcentral.com)
Also, multidrug resistance to ≥ 3 classes of antimicrobials was found in 23.5% (8/34) strains. (bvsalud.org)
Infection2
A disease known as ulcerative lymphagenitis can also result from infection with C. pseudotuberculosis in the distal limbs of horses. (wikipedia.org)
[3] However, intracellular organisms such as Corynebacterium pseudotuberculosis will be susceptible to certain antibiotics in vitro that are not effective for the specific organism in the horse. (wikipedia.org)
Proteins2
Moreover, evidence could be found for probable non-classical export of most of the remaining proteins. (biomedcentral.com)
In fact, one might expect that the majority of the virulence determinants of C. pseudotuberculosis would be present in the exoproteome, i.e . the entire set of bacterial proteins found in the extracellular milieu [ 7 ]. (biomedcentral.com)
Ulcerative1
Corynebacterium pseudotuberculosis has been cultured from some cases (particularly of ulcerative lymphangitis, but in others, a bacterial culture is negative. (wikipedia.org)
Patterns1
As vector patterns change with warming temperatures, C. pseudotuberculosis in horses is re-emerging in the United States. (wikipedia.org)
Hosts1
They are found within vertebrates, invertebrate cells, and amoebae hosts. (up.ac.za)
Ideally, an abscess should only be lanced after it has matured well and has an obvious soft spot, or the procedure should be guided with ultrasound to find the best site for drainage that avoids important structures. (wikipedia.org)
Horses2
Corynebacterium pseudotuberculosis is a Gram-positive bacterium known globally to infect ruminants, horses, and rarely people. (wikipedia.org)
As vector patterns change with warming temperatures, C. pseudotuberculosis in horses is re-emerging in the United States. (wikipedia.org)
citation needed] Although few recent studies have been conducted into its prevalence, data from slaughterhouses in Australia in the late 1980s suggested that C. pseudotuberculosis was affecting 50-60% of sheep. (wikipedia.org)
Volume1
We did not find changes in either packed cell volume, which is an internal control for volemic changes, or thrombocytes (data not shown). (mdmsignaling.com)
Significant1
In contrast, we found a significant effect of supplementation on basophils and lymphocytes in response to exercise. (mdmsignaling.com)