in 1996 reported the following symptoms in order of frequency of occurrence: Bone pain Retroperitoneal fibrosis Diabetes insipidus Exophthalmos Xanthomas Neurological and central nervous system involvement Dyspnea caused by interlobular septal and pleural thickening Kidney failure Hypopituitarism Liver failure Radiologic osteosclerosis and histology are the main diagnostic features. (wikipedia.org)
Liver involvement was one of the first extraglandular manifestations to be reported in patients with primary Sjögren syndrome (SS). (xiahepublishing.com)
PBC-related SS patients may have a broad spectrum of abnormalities of the liver, including having no clinical or analytical data suggestive of liver disease. (xiahepublishing.com)
Involvement1
This can include kidney, skin, brain and lung involvement, and less frequently retroorbital tissue, pituitary gland and heart involvement is observed. (wikipedia.org)
Symptoms1
1 Although xerophthalmia and xerostomia are the most frequent sicca symptoms, nearly 30% of patients present with extraglandular manifestations, and 5% may develop a hematological neoplasia. (xiahepublishing.com)
Biopsy1
Renal biopsy revealed vasculitis of the interlobular arteries as the cause of glomerulonephritis and interstitial nephritis. (bvsalud.org)
Diabetes3
in 1996 reported the following symptoms in order of frequency of occurrence: Bone pain Retroperitoneal fibrosis Diabetes insipidus Exophthalmos Xanthomas Neurological and central nervous system involvement Dyspnea caused by interlobular septal and pleural thickening Kidney failure Hypopituitarism Liver failure Radiologic osteosclerosis and histology are the main diagnostic features. (wikipedia.org)
they can be found in cases of long-standing chronic kidney disease of any etiology, including in patients who are normotensive, particularly those of advanced age or with diabetes. (medscape.com)
Some authors suggest that many of these cases are more likely related to other factors, including small-vessel injury related to aging, diabetes, or obesity-related kidney injury. (medscape.com)
Kidney2
This can include kidney, skin, brain and lung involvement, and less frequently retroorbital tissue, pituitary gland and heart involvement is observed. (wikipedia.org)
Herein, we describe a case of periaortitis accompanied by retroperitoneal ï¬ brosis in a patient who developed acute kidney insufficiency due to bilateral ureteral stenosis. (bvsalud.org)
Patients1
METHODS: This single-centre retrospective study included 15 patients with MPA who underwent echocardiography within 2 weeks of commencing steroid therapy for induction or reinduction. (bvsalud.org)