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  • endometrial
  • Endometrial IL-18 receptor mRNA and the ratio of IL-18 binding protein to interleukin 18 are significantly increased in adenomyosis patients in comparison to normal people, indicating a role in its pathogenesis. (wikipedia.org)
  • cells
  • When administered, these high-dose interleukins trigger healthy cells to redouble their efforts in fighting cancerous cells and other threats to the body. (wisegeek.com)
  • Another part of the body's immune system makeup - T suppressor cells - are meant to signal an end to fighting once the body has won, and interleukins are critical to getting the word out. (wisegeek.com)
  • Problems may arise, however, when the appropriate cells don't get the interleukins' message to stop fighting, chose to ignore the message to stop or receive a message to keep fighting because malfunctioning T cells incorrectly believe that some infection remains. (wisegeek.com)
  • The name is something of a relic, though (the term was coined by Dr Vern Paetkau, University of Victoria) it has since been found that interleukins are produced by a wide variety of body cells. (wikipedia.org)
  • These factors, which include interleukin 2 (IL2), are secreted by lectin- or antigen-stimulated T cells, and have various physiological effects. (wikipedia.org)
  • Interleukin-21 is a cytokine that has potent regulatory effects on cells of the immune system, including natural killer (NK) cells and cytotoxic T cells that can destroy virally infected or cancerous cells. (wikipedia.org)
  • Interleukin-21 is also produced by Hodgkin's lymphoma (HL) cancer cells (which is surprising because IL-21 was thought to be produced only in T cells). (wikipedia.org)
  • trigger
  • When psychologically stressed, the human body produces stress hormones like cortisol, which are able to trigger interleukin-6 release into the circulation. (wikipedia.org)