• immune system
  • The role of interleukins within the immune system has led to their use in fighting some types of cancer and diseases including rheumatoid arthritis and Crohn's disease. (wisegeek.com)
  • Biological therapy using interleukins also can help rebuild an immune system practically eliminated by the sometimes harsh treatments needed to destroy cancerous tumors. (wisegeek.com)
  • While interleukin therapy that boosts the immune system into overdrive can have major health benefits in some situations, an overactive immune system is believed to be the culprit behind autoimmune diseases including lupus , fibromyalgia and multiple sclerosis. (wisegeek.com)
  • Another part of the body's immune system makeup - T suppressor cells - are meant to signal an end to fighting once the body has won, and interleukins are critical to getting the word out. (wisegeek.com)
  • The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. (wikipedia.org)
  • Interleukin 3 is an interleukin, a type of biological signal (cytokine) that can improve the body's natural response to disease as part of the immune system. (wikipedia.org)
  • Interleukin-21 is a cytokine that has potent regulatory effects on cells of the immune system, including natural killer (NK) cells and cytotoxic T cells that can destroy virally infected or cancerous cells. (wikipedia.org)
  • inflammation
  • The different types of interleukins are responsible for triggering an assortment of infection-fighting immune responses, including pain, fever, inflammation , allergic reactions and cell regeneration. (wisegeek.com)
  • Interleukin 13 ( IL-13 ) is a cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells , that is an important mediator of allergic inflammation and disease. (wikidoc.org)
  • Interleukin 6 is secreted by T cells and macrophages to stimulate immune response, e.g. during infection and after trauma, especially burns or other tissue damage leading to inflammation. (wikipedia.org)
  • cells
  • When administered, these high-dose interleukins trigger healthy cells to redouble their efforts in fighting cancerous cells and other threats to the body. (wisegeek.com)
  • Problems may arise, however, when the appropriate cells don't get the interleukins' message to stop fighting, chose to ignore the message to stop or receive a message to keep fighting because malfunctioning T cells incorrectly believe that some infection remains. (wisegeek.com)
  • The name is something of a relic, though (the term was coined by Dr Vern Paetkau, University of Victoria) it has since been found that interleukins are produced by a wide variety of body cells. (wikipedia.org)
  • These factors, which include interleukin 2 (IL2), are secreted by lectin- or antigen-stimulated T cells, and have various physiological effects. (wikipedia.org)
  • Interleukin-21 is also produced by Hodgkin's lymphoma (HL) cancer cells (which is surprising because IL-21 was thought to be produced only in T cells). (wikipedia.org)
  • Interleukin 5 (IL5) is an interleukin produced by type-2 T helper cells and mast cells. (wikipedia.org)
  • Interleukin-5 is also expressed by eosinophils and has been observed in the mast cells of asthmatic airways by immunohistochemistry. (wikipedia.org)
  • acute
  • Interleukin‑6 RNA knockdown ameliorates acute lung injury induced by intestinal ischemia reperfusion in rats by upregulating interleukin‑10 expression. (nih.gov)
  • trigger
  • When psychologically stressed, the human body produces stress hormones like cortisol, which are able to trigger interleukin-6 release into the circulation. (wikipedia.org)