• form gap junctions
  • Though differing in sequence to connexins, innexins are similar enough to connexins to state that innexins form gap junctions in vivo in the same way connexins do. (wikipedia.org)
  • Method: To test this hypothesis we expressed connexin 43 (Cx43) in GJIC-deficient mammary epithelial tumor cells (HBL100) and examined their ability to form gap junctions, establish heterocellular GJIC and migrate through monolayers of human microvascular endothelial cells (HMVEC) grown on matrigel-coated coverslips. (uwo.ca)
  • connexin
  • In vertebrates , gap junction hemichannels are primarily homo- or hetero - hexamers of connexin proteins . (wikipedia.org)
  • In general, allows transmembrane movement of molecules smaller than 485 Daltons (1,100 Daltons through invertebrate gap junctions ), although different connexin subunits may impart different pore sizes and different charge selectivity. (wikipedia.org)
  • Large biomolecules, for example, nucleic acid and protein , are precluded from cytoplasmic transfer between cells through gap junction connexin channels. (wikipedia.org)